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Protein General Information |
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Full Name |
POU class 5 homeobox 1 (POU5F1)
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UniProt ID |
PO5F1_HUMAN
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Gene Name |
POU5F1
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Gene ID |
5460
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Interacting TTD Target Information |
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Interacting Literature-reported Target(s) |
E3 ubiquitin protein ligase Itchy (ITCH) |
Target Info
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PPI Info
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[1] |
NEDD4-like E3 ubiquitin-protein ligase WWP2 (WWP2) |
Target Info
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PPI Info
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[2] |
References |
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REF 1 |
Itch, an E3 ligase of Oct4, is required for embryonic stem cell self-renewal and pluripotency induction. J Cell Physiol. 2013 Jul;228(7):1443-51.
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REF 2 |
WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cells. Cell Res. 2009 May;19(5):561-73.
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