Protein-Protein Interaction Details
Protein General Information | Top | ||||
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Full Name | Proteasome 26S subunit ATPase 3 (PSMC3) | ||||
UniProt ID | PRS6A_HUMAN | ||||
Gene Name | PSMC3 | ||||
Gene ID | 5702 |
Interacting TTD Target Information | Top | ||||
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Interacting Clinical trial Target(s) | Ubiquitin-protein ligase E3 Mdm2 (MDM2) | Target Info | PPI Info | [1] | |
Interacting Patented-recorded Target(s) | Ubiquitin C-terminal hydrolase UCH37 (UCHL5) | Target Info | PPI Info | [2] | |
Polyubiquitin-C (UBC) | Target Info | PPI Info | [3] | ||
Interacting Preclinical Target(s) | Ubiquitin carboxyl-terminal hydrolase 14 (USP14) | Target Info | PPI Info | [2] | |
Interacting Literature-reported Target(s) | Proto-oncogene c-Myc (MYC) | Target Info | PPI Info | [4] | |
Renal carcinoma antigen NY-REN-54 (UBE3A) | Target Info | PPI Info | [5] | ||
Gankyrin (PSMD10) | Target Info | PPI Info | [6] |
References | Top | ||||
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REF 1 | Mutational analysis reveals a dual role of Mdm2 acidic domain in the regulation of p53 stability. FEBS Lett. 2012 Jul 30;586(16):2225-31. | ||||
REF 2 | Defining the human deubiquitinating enzyme interaction landscape. Cell. 2009 Jul 23;138(2):389-403. | ||||
REF 3 | Large-scale analysis of the human ubiquitin-related proteome. Proteomics. 2005 Nov;5(16):4145-51. | ||||
REF 4 | Toward an understanding of the protein interaction network of the human liver. Mol Syst Biol. 2011 Oct 11;7:536. | ||||
REF 5 | Identification and proteomic analysis of distinct UBE3A/E6AP protein complexes. Mol Cell Biol. 2012 Aug;32(15):3095-106. | ||||
REF 6 | Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 17;525(7569):339-44. |
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