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| Protein General Information |
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| Full Name |
Ubiquitin carboxyl-terminal hydrolase 11 (USP11)
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| UniProt ID |
UBP11_HUMAN
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| Gene Name |
USP11
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| Gene ID |
8237
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| Interacting TTD Target Information |
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| Interacting Clinical trial Target(s) |
Mothers against decapentaplegic homolog 7 (SMAD7) |
Target Info
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PPI Info
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[1] |
| Interacting Patented-recorded Target(s) |
Polyubiquitin-C (UBC) |
Target Info
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PPI Info
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[2] |
| Interacting Literature-reported Target(s) |
Melanoma differentiation-associated protein 6 (CDKN1A) |
Target Info
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PPI Info
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[3] |
| References |
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| REF 1 |
USP11 augments TGF signalling by deubiquitylating ALK5. Open Biol. 2012 Jun;2(6):120063.
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| REF 2 |
An Interaction Landscape of Ubiquitin Signaling. Mol Cell. 2017 Mar 2;65(5):941-955.e8.
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| REF 3 |
Deubiquitylation and stabilization of p21 by USP11 is critical for cell-cycle progression and DNA damage responses. Proc Natl Acad Sci U S A. 2018 May 1;115(18):4678-4683.
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