Target Poor or Non Binder(s) Information
Target General Information | Top | ||||
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Target ID | T61746 | Target Info | |||
Target Name | Cathepsin B (CTSB) | ||||
Synonyms |
Ctsb; Cathepsins B; Cathepsin-B; Cathepsin B1; CPSB; APPS; APP secretase
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Target Type | Preclinical Target | ||||
Gene Name | CTSB | ||||
Biochemical Class | Peptidase | ||||
UniProt ID |
Poor Binders of This Target (in total, 243 binders) | Download | Top | |||
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Compound Name |
Cbz-Ile-t-ButylGln-Ala-LeuVSMe
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Investigative | Compound Info | ||
Synonyms |
CHEMBL438612; Cbz-Ile-t-ButylGln-Ala-LeuVSMe
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Activity |
IC50 = 51000 nM
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[1] | |||
Compound Name |
NSC-622445
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Investigative | Compound Info | ||
Synonyms |
5,5'-Methylenedisalicylic acid; 122-25-8; 5,5'-Methylenebis(2-hydroxybenzoic acid); Methylenebis(salicylic acid); 5,5-Methylenebis(salicylic acid); UNII-2KF4FVV76N; 5,5-Methylenedisalicylic acid; 5-(3-Carboxy-4-hydroxybenzyl)salicylic acid; 4,4'-Dihydroxy-3,3'-dicarboxydiphenylmethane; 3,3'-Dicarboxy-4,4'-dihydroxydiphenylmethane; NSC 14778; NSC-622445; 2KF4FVV76N; 4,4'-Dihydroxydiphenylmethane-3,3'-dicarboxylic acid; 3,3'-Methylenebis(6-hydroxybenzoic acid); CHEMBL115145; Benzoic acid, 3,3'-methylenebis[6-hydroxy-
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Activity |
IC50 = 90200 nM
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[2] | |||
Compound Name |
N-(tert-butoxycarbonyl)-leucyl-glycine-nitrile
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Investigative | Compound Info | ||
Synonyms |
dipeptide-derived nitrile, 7; CHEMBL200160; SCHEMBL6257676; BDBM20087; tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-3-methylbutyl]carbamate
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Activity |
Ki = 94000 nM
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[3] | |||
Compound Name |
N-(benzyloxycarbonyl)-leucyl-glycine-nitrile
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Investigative | Compound Info | ||
Synonyms |
dipeptidyl nitrile, 1; Cbz-Leu-NH-CH2-CN; JMC487688 Compound 8; CHEMBL200161; SCHEMBL6183068; BDBM19768; UFXQLUZNMRVTPU-AWEZNQCLSA-N; 2-[(Z-L-Leu-)Amino]ethanenitrile; benzyl (S)-1-cyanomethylcarbamoyl-3-methylbutylcarbamate; benzyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-3-methylbutyl]carbamate
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Activity |
Ki = 123000 nM
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[4] | |||
Compound Name |
Cbz-Ile-MetO2-Ala-LeuVSMe
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Investigative | Compound Info | ||
Synonyms |
CHEMBL383730; Cbz-Ile-MetO2-Ala-LeuVSMe
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Activity |
IC50 = 140000 nM
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[1] | |||
Compound Name |
Ac-hPhe-Leu-Gly-LeuVSMe
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Investigative | Compound Info | ||
Synonyms |
CHEMBL209243; Ac-hPhe-Leu-Gly-LeuVSMe
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Activity |
IC50 ~ 150000 nM
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[1] | |||
Compound Name |
9-(3-Hydroxypropyl)-6-(3-(1-(phenylsulfonyl)-1H-indol-2-yl)benzylamino)-9H-purine-2-carbonitrile
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Investigative | Compound Info | ||
Synonyms |
CHEMBL574590; BDBM50300783
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Activity |
IC50 ~ 50000 nM
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[5] | |||
Compound Name |
(2S)-N-[(1S)-3-Amino-1-cyano-3-oxopropyl]-1-[4-(4-tert-butylphenyl)phenyl]sulfonylpyrrolidine-2-carboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL3741594; BDBM50499737
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Activity |
IC50 ~ 50000 nM
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[6] | |||
Compound Name |
[(S)-2-Phenyl-1-((2S,7R)-5,5,8-trioxo-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-7-ylcarbamoyl)-ethyl]-carbamic acid benzyl ester
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Investigative | Compound Info | ||
Synonyms |
CHEMBL323704; BDBM50121037
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Activity |
IC50 ~ 50000 nM
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[7] | |||
Compound Name |
(2R)-2-Amino-N-[2-(2-naphthalen-2-yl-2-oxoethyl)sulfanyl-1,3-benzothiazol-6-yl]-2-phenylacetamide;hydrochloride
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Investigative | Compound Info | ||
Synonyms |
CHEMBL3218765
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Activity |
IC50 ~ 50000 nM
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[8] | |||
Compound Name |
6-[[3-(3,4-Dichlorophenyl)phenyl]methylamino]-9-(3-hydroxypropyl)purine-2-carbonitrile
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Investigative | Compound Info | ||
Synonyms |
CHEMBL495017; BDBM50258405; 6-((3'',4''-dichlorobiphenyl-3-yl)methylamino)-9-(3-hydroxypropyl)-9H-purine-2-carbonitrile
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Activity |
IC50 ~ 50000 nM
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[5] | |||
Compound Name |
(2S,3S)-2-N-[(2S)-1-[(2S)-2-[[(2S,3R)-1-Amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]-3-N-[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]oxirane-2,3-dicarboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL3289844; BDBM50020427
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Activity |
Ki ~ 50000 nM
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[9] | |||
Compound Name |
(2R)-2-Amino-N-[(1S,2S)-1-cyano-2-phenylcyclopropyl]-3-thiophen-2-ylpropanamide;2,2,2-trifluoroacetic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL478737
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Activity |
IC50 ~ 50000 nM
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[10] | |||
Compound Name |
[(S)-1-((5R,6S)-7-Oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-ethyl]-carbamic acid benzyl ester
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Investigative | Compound Info | ||
Synonyms |
CHEMBL424441; SCHEMBL7435847; BDBM50121032; (5R,6S)-6alpha-[N-(Benzyloxycarbonyl)-L-alanylamino]-4-oxa-1-azabicyclo[3.2.0]heptane-7-one
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Activity |
IC50 ~ 50000 nM
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[11] | |||
Compound Name |
Methyl 4-[3-[[[2-cyano-9-(3-hydroxypropyl)purin-6-yl]amino]methyl]phenyl]benzoate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL571938; BDBM50300782; methyl 3''-((2-cyano-9-(3-hydroxypropyl)-9H-purin-6-ylamino)methyl)biphenyl-4-carboxylate
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Activity |
IC50 ~ 50000 nM
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[5] | |||
Compound Name |
6-[[3-(4-Ethenylphenyl)phenyl]methylamino]-9-(3-hydroxypropyl)purine-2-carbonitrile
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Investigative | Compound Info | ||
Synonyms |
CHEMBL497019; BDBM50268502; 9-(3-hydroxypropyl)-6-((4''-vinylbiphenyl-3-yl)methylamino)-9H-purine-2-carbonitrile
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Activity |
IC50 ~ 50000 nM
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[5] | |||
Compound Name |
(2S)-2-Amino-N-[(1R,2R)-1-cyano-2-phenylcyclopropyl]-3-thiophen-2-ylpropanamide;2,2,2-trifluoroacetic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL516292
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Activity |
IC50 ~ 50000 nM
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[10] | |||
Compound Name |
(2S,3S)-3-N-[(2S)-1-[[(2S)-1-[[(2S,3R)-1-Amino-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-N-[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]oxirane-2,3-dicarboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL3289841; BDBM50020424
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Activity |
Ki ~ 50000 nM
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[9] | |||
Compound Name |
(2S,3S)-3-N-[(2S)-1-[(2S)-2-[[(2S,3R)-1-Amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]-2-N-[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]oxirane-2,3-dicarboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL3289839; BDBM50020422
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Activity |
Ki ~ 50000 nM
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[9] | |||
Compound Name |
1-Butyl-4-(2-(4''-ethylbiphenyl-3-yl)ethyl)-6-ethynyl-1H-indene
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Investigative | Compound Info | ||
Synonyms |
CHEMBL524075; BDBM50268500; 9-(3-hydroxypropyl)-6-((4''-methoxybiphenyl-3-yl)methylamino)-9H-purine-2-carbonitrile
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Activity |
IC50 ~ 50000 nM
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[5] | |||
Compound Name |
9-(3-Hydroxypropyl)-6-(naphthalen-2-ylmethylamino)-9H-purine-2-carbonitrile
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Investigative | Compound Info | ||
Synonyms |
CHEMBL497234; BDBM50268553; 9-(3-hydroxypropyl)-6-(3-(naphthalen-2-yl)benzylamino)-9H-purine-2-carbonitrile
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Activity |
IC50 ~ 50000 nM
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[5] | |||
Compound Name |
[5-Amino-1-(benzenesulfonyl)pyrazol-3-yl] thiophene-2-carboxylate
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Investigative | Compound Info | ||
Synonyms |
MLS000044152; CHEMBL389130; SMR000021562; 5-amino-1-(phenylsulfonyl)-1H-pyrazol-3-yl thiophene-2-carboxylate; PCMD-CC-MCM-1; BDBM32784; cid_3243128; HMS2312L14; MCULE-1690732147; EU-0020340; PC-0051661; SR-01000543659; SR-01000543659-1; [5-azanyl-1-(phenylsulfonyl)pyrazol-3-yl] thiophene-2-carboxylate; thiophene-2-carboxylic acid (5-amino-1-besyl-pyrazol-3-yl) ester; 2-thiophenecarboxylic acid [5-amino-1-(benzenesulfonyl)-3-pyrazolyl] ester
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Activity |
IC50 ~ 50000 nM
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[12] | |||
Compound Name |
(2R)-2-Amino-3-methyl-N-[2-(2-naphthalen-2-yl-2-oxoethyl)sulfanyl-1,3-benzothiazol-6-yl]butanamide;hydrochloride
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Investigative | Compound Info | ||
Synonyms |
CHEMBL3218764
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Activity |
IC50 ~ 50000 nM
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[8] | |||
Compound Name |
6-[[3-(3-Bromo-2-propan-2-yloxyphenyl)phenyl]methylamino]-9-(3-hydroxypropyl)purine-2-carbonitrile
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Investigative | Compound Info | ||
Synonyms |
CHEMBL497620; BDBM50268620; 6-((3''-bromo-2''-isopropoxybiphenyl-3-yl)methylamino)-9-(3-hydroxypropyl)-9H-purine-2-carbonitrile
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Activity |
IC50 ~ 50000 nM
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[5] | |||
Compound Name |
cis-(S)-2-Amino-N-((1R,2R)-1-cyano-2-phenylcyclopropyl)-3-(thiophen-2-yl)propanamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL1078411; BDBM50310690; (2S)-N-[[(1R)-1alpha-Cyano-2beta-phenylcyclopropane]-1-yl]-2-amino-3-(2-thienyl)propanamide
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Activity |
IC50 ~ 50000 nM
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[13] | |||
Compound Name |
6-[[3-(3-Chlorophenyl)phenyl]methylamino]-9-(3-hydroxypropyl)purine-2-carbonitrile
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Investigative | Compound Info | ||
Synonyms |
CHEMBL566094; BDBM50300781; 6-((3''-chlorobiphenyl-3-yl)methylamino)-9-(3-hydroxypropyl)-9H-purine-2-carbonitrile
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Activity |
IC50 ~ 50000 nM
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[5] | |||
Compound Name |
9-(3-Hydroxypropyl)-6-(3-(1-(phenylsulfonyl)-1H-indol-3-yl)benzylamino)-9H-purine-2-carbonitrile
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Investigative | Compound Info | ||
Synonyms |
CHEMBL582971; BDBM50300784
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Activity |
IC50 ~ 50000 nM
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[5] | |||
Compound Name |
[(S)-((5R,6S)-7-Oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-phenyl-methyl]-carbamic acid benzyl ester
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Investigative | Compound Info | ||
Synonyms |
CHEMBL116910; BDBM50121029; (5R,6S)-6alpha-[N-(Benzyloxycarbonyl)-L-phenylglycylamino]-4-oxa-1-azabicyclo[3.2.0]heptane-7-one
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Activity |
IC50 ~ 50000 nM
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[11] | |||
Compound Name |
(5S,6R)-6alpha-[N-(Benzyloxycarbonyl)-L-phenylalanylamino]-4-thia-1-azabicyclo[3.2.0]heptane-7-one
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Investigative | Compound Info | ||
Synonyms |
CHEMBL421054; BDBM50121036
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Activity |
IC50 ~ 50000 nM
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[7] | |||
Compound Name |
(2S)-N-[(1S)-3-Amino-1-cyano-3-oxopropyl]-1-(4-phenylphenyl)sulfonylpyrrolidine-2-carboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL3740601; BDBM50499736
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Activity |
IC50 ~ 50000 nM
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[6] | |||
Compound Name |
(2S)-N-[(1S)-3-Amino-1-cyano-3-oxopropyl]-1-[4-(4-methoxyphenyl)phenyl]sulfonylpyrrolidine-2-carboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL3740153; BDBM50499738
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Activity |
IC50 ~ 50000 nM
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[6] | |||
Compound Name |
2-Amino-N-[(1R,2R)-1-cyano-2-phenylcyclopropyl]-3-(3-fluorothiophen-2-yl)propanamide;2,2,2-trifluoroacetic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL515494
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Activity |
IC50 ~ 50000 nM
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[10] | |||
Compound Name |
6-[[3-(3,5-Dichlorophenyl)phenyl]methylamino]-9-(3-hydroxypropyl)purine-2-carbonitrile
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Investigative | Compound Info | ||
Synonyms |
CHEMBL495016; BDBM50258404; 6-((3'',5''-dichlorobiphenyl-3-yl)methylamino)-9-(3-hydroxypropyl)-9H-purine-2-carbonitrile
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Activity |
IC50 ~ 50000 nM
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[5] | |||
Compound Name |
(2R,3R)-3-N-[(2S)-1-[(2S)-2-[[(2S,3R)-1-Amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]-2-N-[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]oxirane-2,3-dicarboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL3290107; BDBM50020431
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Activity |
Ki ~ 50000 nM
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[9] | |||
Compound Name |
Chembl4228081
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Investigative | Compound Info | ||
Synonyms |
BDBM50461246
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Activity |
IC50 ~ 50000 nM
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[14] | |||
Compound Name |
(2R,3R)-3-N-[(2S)-1-[(2S)-2-[[(2S,3R)-1-Amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]-2-N-[(2S,3R)-1-[(2S)-2-[(2S)-2-[(2S)-2-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl]oxirane-2,3-dicarboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL3290113; BDBM50020437
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Activity |
Ki ~ 50000 nM
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[9] | |||
Compound Name |
6-[[3-(3-Ethenylphenyl)phenyl]methylamino]-9-(3-hydroxypropyl)purine-2-carbonitrile
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Investigative | Compound Info | ||
Synonyms |
CHEMBL497018; BDBM50268501; 9-(3-hydroxypropyl)-6-((3''-vinylbiphenyl-3-yl)methylamino)-9H-purine-2-carbonitrile
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Activity |
IC50 ~ 50000 nM
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[5] | |||
Compound Name |
[(S)-2-Phenyl-1-((6R,7R)-5,5,8-trioxo-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-7-ylcarbamoyl)-ethyl]-carbamic acid benzyl ester
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Investigative | Compound Info | ||
Synonyms |
CHEMBL115822; BDBM50121033
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Activity |
IC50 ~ 50000 nM
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[7] | |||
Compound Name |
(2R)-N-(Cyanomethyl)-2-[3-[3-[2-[3-(dimethylamino)pyrrolidin-1-yl]-1,3-thiazol-4-yl]phenyl]phenyl]-4-methylpentanamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL213244; BDBM50188298
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Activity |
Ki = 51000 nM
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[15] | |||
Compound Name |
(2R)-N-(Cyanomethyl)-4-methyl-2-[3-[3-[2-(piperazin-1-ylmethyl)-1,3-thiazol-4-yl]phenyl]phenyl]pentanamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL213194; BDBM50188294
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Activity |
Ki = 51000 nM
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[15] | |||
Compound Name |
N-[(2S)-1-[[(2S)-1,6-Diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]piperidine-2-carboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382076; BDBM50491314
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Activity |
Ki = 51000 nM
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[16] | |||
Compound Name |
4-(Benzylthio)-6-((cyanomethyl)thio)-1,3,5-triazin-2(1H)-one
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Investigative | Compound Info | ||
Synonyms |
CHEMBL1836514; BDBM50354251
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Activity |
Ki = 51600 nM
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[17] | |||
Compound Name |
Acetic acid (2S,3S)-3-{[(R)-2-((S)-benzyloxycarbonylamino)-cyclopentanecarbonyl]-amino}-4-oxo-azetidin-2-yl ester
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Investigative | Compound Info | ||
Synonyms |
CHEMBL65990; BDBM50129076
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Activity |
Ki = 52000 nM
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[18] | |||
Compound Name |
(5Z)-5-[(2,4-Dihydroxyphenyl)methylidene]-2-sulfanylideneimidazolidin-4-one
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Investigative | Compound Info | ||
Synonyms |
CHEMBL378575; BDBM11980; BHT102866; chemical diversity library compound 5; AKOS027461626; ST003272; 2-Thioxo-5-[(Z)-2,4-dihydroxybenzylidene]imidazolidine-4-one; 5-[(2,4-dihydroxyphenyl)methylene]-2-thioxo-1,3-diazolidin-4-one
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Activity |
IC50 = 52300 nM
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[2] | |||
Compound Name |
Chembl4247075
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Investigative | Compound Info | ||
Synonyms |
BDBM50463153
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Activity |
IC50 = 52600 nM
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[19] | |||
Compound Name |
Cbz-Ile-Gln-Ala-LeuVSMe
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Investigative | Compound Info | ||
Synonyms |
CHEMBL382180; BDBM50186700
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Activity |
IC50 = 54000 nM
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[1] | |||
Compound Name |
(E)-1-(4-Fluorophenyl)-3-(4-pyrrolidin-1-ylphenyl)prop-2-en-1-one
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382118; BDBM50491481
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Activity |
IC50 = 54290 nM
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[20] | |||
Compound Name |
4-(2,5-Dimethyl-1H-pyrrol-1-yl)-2-hydroxybenzoic acid
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Investigative | Compound Info | ||
Synonyms |
4-(2,5-Dimethyl-pyrrol-1-yl)-2-hydroxy-benzoic acid; 4-(2,5-dimethylpyrrol-1-yl)-2-hydroxybenzoic acid; ML040; Benzoic acid, 4-(2,5-dimethyl-1H-pyrrol-1-yl)-2-hydroxy-; 4-(2,5-dimethylpyrrolyl)-2-hydroxybenzoic acid; CBMicro_001509; Oprea1_441093; Oprea1_541097; CHEMBL212723; SCHEMBL3504906; BDBM11985; CTK1H7721; KS-00003KQH; ZINC29121; DTXSID70953413; ALBB-032581; SMSF0010792; 6453AE; BBL012537; MFCD01874283; NSC727423; SBB007408; STK196773; Salicylic acid derivative, compound 1; AKOS000263211; chemical diversity library compound 10; CB02902; FS-2485; MCULE-2662763432; NSC-727423; ST042187; BIM-0001471.P001; BB 0254003; CS-0118708; EU-0071194; FT-0677052; Z-2173; 4-(2,5-dimethylpyrrol-1-yl)-2-hydroxy-benzoic acid; BRD-K60564032-001-01-7; 2-Hydroxy-4-(2,5-dimethyl-1H-pyrrole-1-yl)benzoic acid
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Activity |
IC50 = 55000 nM
|
[2] | |||
Compound Name |
N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-[4-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]sulfonylphenyl]benzamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL197440; BDBM50410593
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Activity |
Ki = 56000 nM
|
[4] | |||
Compound Name |
CID 10302710
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Investigative | Compound Info | ||
Synonyms |
CHEMBL188563; BDBM50169486
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Activity |
IC50 = 56000 nM
|
[21] | |||
Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]carbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382060; BDBM50491297
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Activity |
Ki = 56000 nM
|
[16] | |||
Compound Name |
N-[1-[[(2S)-1-[5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]-1-oxopentan-2-yl]carbamoyl]cyclohexyl]-4-(trifluoromethoxy)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL210198; SCHEMBL7537053; BDBM50374297
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Activity |
Ki = 57000 nM
|
[22] | |||
Compound Name |
Echinatin
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Investigative | Compound Info | ||
Synonyms |
3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one; 4,4'-DIHYDROXY-2-METHOXYCHALCONE; Retrochalcone; UNII-3816S4UA9R; (E)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one; CHEMBL141530; 3816S4UA9R; (E)-3-(4-Hydroxy-2-methoxy-phenyl)-1-(4-hydroxy-phenyl)-propenone; Echinantin; SCHEMBL618086; 4'-Dihydroxy-2-methoxychalcone; 4',4-dihydroxy-2-methoxychalcone; DTXSID301019928; HY-N0269; ZINC4252572; BDBM50068267; LMPK12120431; MFCD00075719; s9437; 2-Propen-1-one, 3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-, (2E)-; AKOS016010242; CCG-267154; CS-0008288; N2427; ST50331404; Y0074; A14853; Q27256724; (2E)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one; (E)-3-(4-hydroxy-2-methoxy-phenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
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Activity |
IC50 = 57680 nM
|
[20] | |||
Compound Name |
(4As,10S,10aR)-8-(5-chloropyridin-3-yl)-4a-methylspiro[2,3,4,10a-tetrahydropyrano[3,2-b]chromene-10,4'-5H-1,3-thiazole]-2'-amine
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Investigative | Compound Info | ||
Synonyms |
CHEMBL3357666; BDBM50033398
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Activity |
IC50 = 58000 nM
|
[23] | |||
Compound Name |
7-[(Benzylamino)methyl]-5-nitroquinolin-8-ol
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2312212; BDBM50425033
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Activity |
Ki = 58000 nM
|
[24] | |||
Compound Name |
Benzyl N-[(2S)-3-[4-(3-chlorophenyl)phenyl]-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]carbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382000; BDBM50491307
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||||
Activity |
Ki = 58000 nM
|
[16] | |||
Compound Name |
3-[(4As,10R,10aR)-2'-amino-4a-methylspiro[2,3,4,10a-tetrahydropyrano[3,2-b]chromene-10,4'-5H-1,3-oxazole]-8-yl]benzonitrile
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Investigative | Compound Info | ||
Synonyms |
CHEMBL3357669; SCHEMBL9882529; BDBM50033410
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||||
Activity |
IC50 = 58000 nM
|
[23] | |||
Compound Name |
{[4-(2,5-Dimethyl-1H-pyrrol-1-yl)phenyl]sulfanyl}acetic acid
Click to Show/Hide
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Investigative | Compound Info | ||
Synonyms |
Interchim compound 56; CBMicro_038314; ChemDiv2_000618; Oprea1_159453; Oprea1_564740; yl)phenyl]sulfanyl}acetic acid; CHEMBL386313; SCHEMBL9744356; BDBM11994; 2-[4-(2,5-dimethylpyrrol-1-yl)phenyl]sulfanylacetic acid; DTXSID00354237; HMS1370M02; SP734; ZINC244550; 2-[[4-(2,5-dimethyl-1H-pyrrol-1-yl)phenyl]thio]Acetic acid; NSC731231; STL302399; AKOS000100942; CCG-106257; MCULE-5832604129; NSC-731231; 2-{[4-(2,5-dimethyl-1H-pyrrol-1-; DA-18382; BIM-0038342.P001; CS-0117920; FT-0704800; ST50008603; SR-01000430219; 2-[4-(2,5-dimethylpyrrolyl)phenylthio]acetic acid; SR-01000430219-1; 2-[4-(2,5-dimethyl-1H-pyrrol-1-yl)-phenylthio]-acetic acid; 2-{[4-(2,5-dimethyl-1H-pyrrol-1-yl)phenyl]sulfanyl}acetic acid
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Activity |
IC50 = 58300 nM
|
[2] | |||
Compound Name |
(S)-2-((S)-2-(3,3-Dimethylbutanamido)-3,3-dimethylbutanamido)-N4,N4-dimethyl-N1-(1-(oxazolo[4,5-b]pyridin-2-yl)-1-oxopropan-2-yl)succinamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL133016; SCHEMBL6558957; BDBM50061500
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||||
Activity |
IC50 = 59000 nM
|
[25] | |||
Compound Name |
5-Chloro-2-[5-[(Z)-(3,8-dioxo-5,16-dithia-2,7-diazatetracyclo[7.7.0.02,6.010,15]hexadeca-1(9),6,10(15)-trien-4-ylidene)methyl]furan-2-yl]benzoic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL215448
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Activity |
IC50 = 59400 nM
|
[2] | |||
Compound Name |
Chembl4245255
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Investigative | Compound Info | ||
Synonyms |
BDBM50463237
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Activity |
IC50 = 60000 nM
|
[26] | |||
Compound Name |
(S)-3,3-Dimethyl-1-(2-oxo-3-(4-(trifluoromethyl)phenyl)imidazolidin-1-yl)butan-2-yl(S)-1-(1H-pyrazol-5-ylamino)-1,2-dioxoheptan-3-ylcarbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL191178; BDBM50169490
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Activity |
IC50 = 60000 nM
|
[21] | |||
Compound Name |
Dipeptide-derived nitrile, 17
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Investigative | Compound Info | ||
Synonyms |
CHEMBL344174; BDBM20096; benzyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-phenylethyl]carbamate
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Activity |
IC50 = 62000 nM
|
[27] | |||
Compound Name |
Benzyl N-[(2S)-1-(cyanomethylamino)-4,4-dimethyl-1-oxopentan-2-yl]carbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL200529; BDBM50410605
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Activity |
Ki = 63000 nM
|
[4] | |||
Compound Name |
2-Chloro-5-[[(4Z)-4-[(4-methylsulfanylphenyl)methylidene]-5-oxoimidazol-1-yl]sulfamoyl]benzoic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL213158
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Activity |
IC50 = 63100 nM
|
[2] | |||
Compound Name |
(1R,2R,4R)-4-(Benzenesulfonyl)-N-(1-cyanocyclopropyl)-2-(3-hydroxyazetidine-1-carbonyl)cyclopentane-1-carboxamide
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Investigative | Compound Info | ||
Synonyms |
SCHEMBL1139578; CHEMBL3093930
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||||
Activity |
IC50 = 63300 nM
|
[28] | |||
Compound Name |
(4As,10S,10aR)-4a-methyl-8-pyrimidin-5-ylspiro[2,3,4,10a-tetrahydropyrano[3,2-b]chromene-10,4'-5H-1,3-thiazole]-2'-amine
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Investigative | Compound Info | ||
Synonyms |
CHEMBL3357672; BDBM50033413
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Activity |
IC50 = 64000 nM
|
[23] | |||
Compound Name |
Chembl4228186
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Investigative | Compound Info | ||
Synonyms |
BDBM50460483
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Activity |
Ki = 64000 nM
|
[29] | |||
Compound Name |
Benzyl 1-((cyanomethyl)carbamoyl)cyclohexylcarbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL200151; Benzyl N-[1-(cyanomethylcarbamoyl)cyclohexyl]carbamate; SCHEMBL6184084; BDBM50410608
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Activity |
Ki = 64000 nM
|
[4] | |||
Compound Name |
4-{5-[(Z)-(5-Cyano-2-hydroxy-4-methyl-6-oxopyridin-3(6H)-ylidene)methyl]furan-2-yl}benzenesulfonamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL213144; SCHEMBL14680268; HMS1679O11; STK333494; ZINC12730092; AKOS000543589; AKOS003212262; AKOS005153598
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Activity |
IC50 = 64800 nM
|
[2] | |||
Compound Name |
2-((2S,3S)-2-Acetoxy-4-oxo-azetidin-3-ylcarbamoyl)-piperidine-1-carboxylic acid benzyl ester
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Investigative | Compound Info | ||
Synonyms |
CHEMBL62923; BDBM50129074
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Activity |
Ki = 65000 nM
|
[18] | |||
Compound Name |
Chembl4228583
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Investigative | Compound Info | ||
Synonyms |
BDBM50460485
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Activity |
Ki = 66000 nM
|
[29] | |||
Compound Name |
Chembl4228126
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Investigative | Compound Info | ||
Synonyms |
BDBM50460481
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Activity |
Ki = 67000 nM
|
[29] | |||
Compound Name |
8-Hydroxy-5-nitroquinoline-2-carbonitrile
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Investigative | Compound Info | ||
Synonyms |
CHEMBL4228345; BDBM50460494; ZINC225963431; AK00740570
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||||
Activity |
Ki = 68000 nM
|
[29] | |||
Compound Name |
Benzyl N-[(2S,3S)-1-(cyanomethylamino)-3-methyl-1-oxopentan-2-yl]carbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL382971; BDBM50410582
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||||
Activity |
Ki = 70000 nM
|
[4] | |||
Compound Name |
4-Benzylsulfanyl-6-butylsulfanyl-1H-1,3,5-triazin-2-one
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Investigative | Compound Info | ||
Synonyms |
CHEMBL1836513; BDBM50354248
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||||
Activity |
Ki = 70600 nM
|
[17] | |||
Compound Name |
(2S)-N'-(2,2-Dimethylpropyl)-N-[(2S)-1-[[(2S)-4-methyl-1-oxo-1-(5-phenyl-1,3,4-oxadiazol-2-yl)pentan-2-yl]amino]-1-oxopropan-2-yl]-2-[(4-methylphenyl)sulfonylamino]butanediamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL383674; BDBM50410899
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Activity |
Ki = 72000 nM
|
[1] | |||
Compound Name |
5,7-Dinitroquinolin-8-ol
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Investigative | Compound Info | ||
Synonyms |
5,7-Dinitro-8-quinolinol; 8-Quinolinol, 5,7-dinitro-; NSC57103; 8-Quinolinol,5,7-dinitro-; MLS000737318; CHEMBL241898; 8-Quinolinol,5,7-dinitro; NCIOpen2_004142; Oprea1_223273; SCHEMBL8164006; 5,7-dinitro-8-hydroxyquinoline; CTK4A6035; DTXSID30288652; ZINC5813787; AB3684; BDBM50425026; MFCD00024022; NSC-57103; STL573068; AKOS023552893; MCULE-9056199203; SMR000528263; ST092906; DS-006066; SR-01000195513; SR-01000195513-1
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Activity |
Ki = 72000 nM
|
[24] | |||
Compound Name |
2-Hydroxy-5-(5-{(Z)-[2-imino-4-oxo-3-(1,3-thiazol-2-yl)-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)benzoic acid
Click to Show/Hide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL386364; BDBM11987; STK678457; ZINC12428587; AKOS001729321; chemical diversity library compound 12; MCULE-5345662084; ST032629; SR-01000537883; SR-01000537883-1
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Activity |
IC50 = 72300 nM
|
[2] | |||
Compound Name |
N-[1-[[(2S)-1-Oxo-1-(5-phenyl-1,3,4-oxadiazol-2-yl)pentan-2-yl]carbamoyl]cyclohexyl]-4-(trifluoromethoxy)benzamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL211050; BDBM50374293
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||||
Activity |
Ki = 73000 nM
|
[22] | |||
Compound Name |
(1R,2R)-N-[(1S)-1-Cyanoethyl]-2-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indole-2-carbonyl)cyclohexane-1-carboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2164680; BDBM50395222
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Activity |
IC50 = 73500 nM
|
[30] | |||
Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-[4-(4-phenylphenyl)phenyl]propan-2-yl]carbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382004; BDBM50491305
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Activity |
Ki = 74000 nM
|
[16] | |||
Compound Name |
(1r,2s)-Ethyl 2-[[(8-hydroxy-5-nitroquinolin-7-yl)methyl]amino]cyclohexanecarboxylate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2312219; BDBM50425027
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Activity |
Ki = 74000 nM
|
[24] | |||
Compound Name |
Chembl4240103
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Investigative | Compound Info | ||
Synonyms |
BDBM50463224
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Activity |
IC50 = 74000 nM
|
[26] | |||
Compound Name |
2-Oxo-4-phenacylsulfanyl-N-[(1R)-1-phenylethyl]azetidine-1-carboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL433040; BDBM50070438; N-((1R)-1-Phenylethyl)[2-oxo-4-(2-oxo-2-phenylethylthio)azetidinyl]carboxamide; 2-Oxo-4-(2-oxo-2-phenyl-ethylsulfanyl)-azetidine-1-carboxylic acid ((R)-1-phenyl-ethyl)-amide
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Activity |
IC50 ~ 75000 nM
|
[31] | |||
Compound Name |
N-((1S)-2-Hydroxy-1-phenylethyl)[2-oxo-4-(2-pyridylmethylthio)azetidinyl]carboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL36353; BDBM50070449; N-[(1S)-2-hydroxy-1-phenyl-ethyl]-2-oxo-4-(2-pyridylmethylsulfanyl)azetidine-1-carboxamide
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Activity |
IC50 ~ 75000 nM
|
[31] | |||
Compound Name |
(2S)-N-[(1S)-3-Methyl-1-({4-oxo-1-[N-benzylcarbamoyl]azetidin-2-yloxy}methyl)butyl]-2-[(tert-butoxy)carbonylamino]-3,3-dimethylbutanamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL263736; BDBM50070442
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Activity |
IC50 ~ 75000 nM
|
[31] | |||
Compound Name |
N-((1R)-1-Phenylethyl)[2-oxo-4-(2-pyridylmethylthio)azetidinyl]carboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL287467; BDBM50070445; 2-oxo-N-[(1R)-1-phenylethyl]-4-(2-pyridylmethylsulfanyl)azetidine-1-carboxamide; 2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-carboxylic acid ((R)-1-phenyl-ethyl)-amide
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Activity |
IC50 ~ 75000 nM
|
[31] | |||
Compound Name |
N-((1R)-1-Phenylpropyl)[2-oxo-4-(2-pyridylmethylthio)azetidinyl]carboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL35797; BDBM50070435; 2-oxo-N-[(1R)-1-phenylpropyl]-4-(2-pyridylmethylsulfanyl)azetidine-1-carboxamide; 2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-carboxylic acid ((R)-1-phenyl-propyl)-amide
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Activity |
IC50 ~ 75000 nM
|
[31] | |||
Compound Name |
N-((1R)-1-Phenylethyl)(2-oxo-4-phenylthioazetidinyl)carboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL32486; BDBM50065878; 2-oxo-N-[(1R)-1-phenylethyl]-4-phenylsulfanyl-azetidine-1-carboxamide; 2-Oxo-4-phenylsulfanyl-azetidine-1-carboxylic acid ((R)-1-phenyl-ethyl)-amide
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||||
Activity |
IC50 ~ 75000 nM
|
[31] | |||
Compound Name |
N-((1R)-1-Phenylethyl)[2-oxo-4-(3-pyridylmethylthio)azetidinyl]carboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL32171; BDBM50070441; 2-oxo-N-[(1R)-1-phenylethyl]-4-(3-pyridylmethylsulfanyl)azetidine-1-carboxamide; 2-Oxo-4-(pyridin-3-ylmethylsulfanyl)-azetidine-1-carboxylic acid ((R)-1-phenyl-ethyl)-amide
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Activity |
IC50 ~ 75000 nM
|
[31] | |||
Compound Name |
Tert-butyl 2-[4-[[4-oxo-1-[[(1R)-1-phenylethyl]carbamoyl]azetidin-2-yl]sulfanylmethyl]phenyl]acetate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL288793; BDBM50070434; tert-Butyl 2-[4-({1-[N-((1R)-1-phenylethyl)carbamoyl]-4-oxoazetidin-2-ylthio}methyl)phenyl]acetate
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Activity |
IC50 ~ 75000 nM
|
[31] | |||
Compound Name |
[2-Oxo-4-(2-pyridylmethylthio)azetidinyl]-N-[2-(phenylmethoxy)ethyl]carboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL36010; BDBM50070436; 2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-carboxylic acid (2-benzyloxy-ethyl)-amide; N-(2-benzyloxyethyl)-2-oxo-4-(2-pyridylmethylsulfanyl)azetidine-1-carboxamide
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Activity |
IC50 ~ 75000 nM
|
[31] | |||
Compound Name |
{(S)-1-[(S)-1-(1-Benzylcarbamoyl-4-oxo-azetidin-2-ylsulfanylmethyl)-3-methyl-butylcarbamoyl]-2,2-dimethyl-propyl}-carbamic acid tert-butyl ester
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Investigative | Compound Info | ||
Synonyms |
CHEMBL35762; BDBM50070440
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Activity |
IC50 ~ 75000 nM
|
[31] | |||
Compound Name |
2-[(2S)-2-[[(2S)-2-(3,3-Dimethylbutanoylamino)-3,3-dimethylbutanoyl]amino]-4-methylpentyl]sulfanyl-4-oxo-N-[(1S)-1-phenylpropyl]azetidine-1-carboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL35353; BDBM50070439
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|
||||
Activity |
IC50 ~ 75000 nM
|
[31] | |||
Compound Name |
((S)-2,2-Dimethyl-1-{(S)-3-methyl-1-[4-oxo-1-((R)-1-phenyl-ethylcarbamoyl)-azetidin-2-yloxymethyl]-butylcarbamoyl}-propyl)-carbamic acid tert-butyl ester
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Investigative | Compound Info | ||
Synonyms |
CHEMBL285920; BDBM50070443
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||||
Activity |
IC50 ~ 75000 nM
|
[31] | |||
Compound Name |
2-Oxo-4-phenethylsulfanyl-N-[(1R)-1-phenylethyl]azetidine-1-carboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL286322; BDBM50070437; N-((1R)-1-Phenylethyl)[2-oxo-4-(2-phenylethylthio)azetidinyl]carboxamide; 2-Oxo-4-phenethylsulfanyl-azetidine-1-carboxylic acid ((R)-1-phenyl-ethyl)-amide
Click to Show/Hide
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||||
Activity |
IC50 ~ 75000 nM
|
[31] | |||
Compound Name |
N-[(1-Cyanopyrrolidin-2-yl)methyl]benzamide
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|
Investigative | Compound Info | ||
Synonyms |
CHEMBL8480; SCHEMBL6856184; BDBM50095497; N-(1-Cyano-pyrrolidin-2-ylmethyl)-benzamide; N-[(1-cyano-2-pyrrolidinyl)methyl]benzamide; 2-[(Benzoylamino)methyl]pyrrolidine-1-carbonitrile
Click to Show/Hide
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||||
Activity |
IC50 = 75000 nM
|
[32] | |||
Compound Name |
((S)-2,2-Dimethyl-1-{(S)-3-methyl-1-[4-oxo-1-((S)-1-phenyl-ethylcarbamoyl)-azetidin-2-yloxymethyl]-butylcarbamoyl}-propyl)-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL32166; BDBM50070446
Click to Show/Hide
|
||||
Activity |
IC50 ~ 75000 nM
|
[31] | |||
Compound Name |
2-Benzylsulfanyl-4-oxo-N-[(1R)-1-phenylethyl]azetidine-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL32918; BDBM50070448; N-((1R)-1-Phenylethyl)[2-oxo-4-(phenylmethylthio)azetidinyl]carboxamide; 2-Benzylsulfanyl-4-oxo-azetidine-1-carboxylic acid ((R)-1-phenyl-ethyl)-amide
Click to Show/Hide
|
||||
Activity |
IC50 ~ 75000 nM
|
[31] | |||
Compound Name |
(3R,4S)-3-Methyl-2-oxo-N-[(1R)-1-phenylpropyl]-4-(pyridin-2-ylmethylsulfanyl)azetidine-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL34840; BDBM50070444
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|
||||
Activity |
IC50 ~ 75000 nM
|
[31] | |||
Compound Name |
N-((1R)-1-Phenylethyl)[2-oxo-4-(4-pyridylmethylthio)azetidinyl]carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL32559; BDBM50070447; 2-oxo-N-[(1R)-1-phenylethyl]-4-(4-pyridylmethylsulfanyl)azetidine-1-carboxamide; 2-Oxo-4-(pyridin-4-ylmethylsulfanyl)-azetidine-1-carboxylic acid ((R)-1-phenyl-ethyl)-amide
Click to Show/Hide
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||||
Activity |
IC50 ~ 75000 nM
|
[31] | |||
Compound Name |
3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(dimethylamino)-propyl)-2-oxophenylbutanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL1242932; BDBM50326306
Click to Show/Hide
|
||||
Activity |
Ki = 75500 nM
|
[33] | |||
Compound Name |
4-[4-[4-(Tert-butylamino)piperidin-1-yl]phenyl]-N-[1-(cyanomethylcarbamoyl)cyclohexyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL199163; BDBM50177771
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|
||||
Activity |
Ki = 76000 nM
|
[4] | |||
Compound Name |
2-[[(8-Hydroxy-5-nitroquinolin-7-yl)methyl](methyl)amino]acetonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2312215; BDBM50425031
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|
||||
Activity |
Ki = 76000 nM
|
[24] | |||
Compound Name |
(2E)-1-(4-Aminophenyl)-3-(4-hydroxy-2-methoxyphenyl)prop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382114; ALBB-007900; BDBM50491468; MFCD12027527; STK504890; ZINC22864728; AKOS005171835
Click to Show/Hide
|
||||
Activity |
IC50 = 76470 nM
|
[20] | |||
Compound Name |
2-Methyl-5-nitroquinoline-8-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
2-methyl-5-nitroquinolin-8-ol; CHEMBL4229176; SCHEMBL8381316; DTXSID10876218; 8-Quinolinol, 2-methyl-5-nitro-; BDBM50460480
Click to Show/Hide
|
||||
Activity |
Ki = 77000 nM
|
[29] | |||
Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-(4-phenylphenyl)propan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2381998; BDBM50491295
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|
||||
Activity |
Ki = 77000 nM
|
[16] | |||
Compound Name |
Ac-Glu(OtBu)-Ala-LeuVSMe
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Investigative | Compound Info | ||
Synonyms |
CHEMBL383529; BDBM50186689
Click to Show/Hide
|
||||
Activity |
IC50 = 77000 nM
|
[1] | |||
Compound Name |
2-[Benzyl[(8-hydroxy-5-nitroquinolin-7-yl)methyl]amino]acetonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2312214; BDBM50425013
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|
||||
Activity |
Ki = 79000 nM
|
[24] | |||
Compound Name |
N-[(2S)-1-[[(2S)-1,6-Diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyridine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382073; BDBM50491287
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|
||||
Activity |
Ki = 80000 nM
|
[16] | |||
Compound Name |
N-[(2-Cyanopyrimidin-4-yl)methyl]-3-[2-(3,5-dichlorophenyl)-2-methylpropanoyl]-4-[2-(dimethylamino)ethoxy]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3354495; BDBM50042856
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|
||||
Activity |
IC50 = 81000 nM
|
[34] | |||
Compound Name |
4-(5-{(Z)-[1-(4-Chlorophenyl)-3,5-dioxopyrazolidin-4-ylidene]methyl}-2-furyl)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL386614; ZINC6221909; CCG-14524; AKOS000112721; BIM-0016047.P001; SR-01000110231; SR-01000110231-1
Click to Show/Hide
|
||||
Activity |
IC50 = 81500 nM
|
[2] | |||
Compound Name |
7-[(Ethylamino)methyl]-5-nitroquinolin-8-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2312213; BDBM50425032
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|
||||
Activity |
Ki = 82000 nM
|
[24] | |||
Compound Name |
N-[(2S)-1-[[(2S)-1,6-Diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-4-phenylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382065; BDBM50491302
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|
||||
Activity |
Ki = 84000 nM
|
[16] | |||
Compound Name |
4-Nitro-1-naphthol
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
4-nitronaphthalen-1-ol; 1-Naphthalenol, 4-nitro-; 1-Hydroxy-4-nitronaphthalene; 4-nitronaphthol; CHEMBL2312200; 4-Nitronaphthalenol; NSC400336; PubChem13796; ACMC-209mko; 4-nitro-1-naphthalenol; 4-nitro-naphthalen-1-ol; 1-Naphthalenol,4-nitro-; 4-nitro-1-hydroxynaphthalene; SCHEMBL589663; CTK5B1742; DTXSID00209238; ACN-S002712; ALBB-014693; ANW-33526; BBL101777; BDBM50425036; MFCD02179392; SBB067137; STL555574; ZINC35193837; AKOS005174640; MCULE-5007401844; NSC-400336; AC-29203; AS-13065; SC-45968; AB0012922; DB-053652; AM20040822; FT-0632516; N0672; R5601; ST50408514; A832781; F1905-7194; Z2607956390
Click to Show/Hide
|
||||
Activity |
Ki = 84000 nM
|
[24] | |||
Compound Name |
4-(4-Nitronaphthalen-1-yl)morpholine
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|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2312202; SCHEMBL4871412; CTK3C5705; DTXSID00740035; BDBM50425018; Morpholine, 4-(4-nitro-1-naphthalenyl)-
Click to Show/Hide
|
||||
Activity |
Ki = 85000 nM
|
[24] | |||
Compound Name |
2-(2-Ethylphenylsulfonyl)oxirane
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|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2387617; BDBM50491873
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|
||||
Activity |
Ki = 86000 nM
|
[35] | |||
Compound Name |
(2R)-N-(Cyanomethyl)-4-methyl-2-[3-(4-piperazin-1-ylphenyl)phenyl]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL184514; SCHEMBL1587727; BDBM19856; piperazine-containing compound, 11; JMC463709 (R)-2; (2R)-N-(cyanomethyl)-4-methyl-2-{3-[4-(piperazin-1-yl)phenyl]phenyl}pentanamide; (r)-N-(cyanomethyl)-4-methyl-2-(4'-(piperazin-1-yl)-[1,1'-biphenyl]-3-yl)pentanamide
Click to Show/Hide
|
||||
Activity |
IC50 = 86000 nM
|
[36] | |||
Compound Name |
Ethyl 4-[(8-hydroxy-5-nitroquinolin-7-yl)methyl]piperazine-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2312218; BDBM50425028
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|
||||
Activity |
Ki = 87000 nM
|
[24] | |||
Compound Name |
N-[(2-Pyridinyl)methyl]-5-nitroquinoline-8-amine-
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2312209; BDBM50425021; AKOS009153200
Click to Show/Hide
|
||||
Activity |
Ki = 87000 nM
|
[24] | |||
Compound Name |
2-Chloro-5-[(4Z)-4-[[5-(4-chlorophenyl)furan-2-yl]methylidene]-3,5-dioxopyrazolidin-1-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL385899
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|
||||
Activity |
IC50 = 88900 nM
|
[2] | |||
Compound Name |
Chembl4226425
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|
Investigative | Compound Info | ||
Synonyms |
BDBM50460496
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|
||||
Activity |
Ki = 94000 nM
|
[29] | |||
Compound Name |
5-Nitro-7-[[4-(pyridin-4-ylmethyl)piperazin-1-yl]methyl]quinolin-8-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2312211; BDBM50425034
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|
||||
Activity |
Ki = 94000 nM
|
[24] | |||
Compound Name |
Cbz-Phe-[Gly-cis epoxy-Gly]-Ala-AlaOMe
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL525792; BDBM50265074
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|
||||
Activity |
Ki = 94000 nM
|
[37] | |||
Compound Name |
(E)-1-(4-Fluorophenyl)-3-(4-hydroxy-2-methoxyphenyl)prop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382112; BDBM50491469
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|
||||
Activity |
IC50 = 95090 nM
|
[20] | |||
Compound Name |
Chembl4228452
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|
Investigative | Compound Info | ||
Synonyms |
BDBM50460492
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|
||||
Activity |
Ki = 96000 nM
|
[29] | |||
Compound Name |
2-(Morpholin-4-ylmethyl)-4-nitrophenol
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL4226620; Cambridge id 5421315; Oprea1_011956; SCHEMBL922732; ZINC4987106; BDBM50460497; MCULE-8424007523; AB00084657-01; SR-01000208507; SR-01000208507-1
Click to Show/Hide
|
||||
Activity |
Ki = 97000 nM
|
[29] | |||
Compound Name |
4-(Benzylthio)-6-(ethylthio)-1,3,5-triazin-2(1H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL1836511; BDBM50354252
Click to Show/Hide
|
||||
Activity |
Ki = 97100 nM
|
[17] | |||
Compound Name |
N-(Cyanomethyl)-1-(3-phenylpropanoylamino)cyclohexane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL372139; SCHEMBL6183662; BDBM50410610
Click to Show/Hide
|
||||
Activity |
Ki = 99000 nM
|
[4] | |||
Compound Name |
(2S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-4-methyl-2-[[(1S)-2,2,2-trifluoro-1-[4-(4-methylsulfonylphenyl)phenyl]ethyl]amino]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL399359; SCHEMBL4193792; BDBM50214546
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[38] | |||
Compound Name |
(E)-3-(3-Bromo-4-methoxyphenyl)-1-(furan-2-yl)prop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382059; BDBM50491475
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[20] | |||
Compound Name |
(2S)-2-[[2-(3,5-Dichlorophenyl)acetyl]amino]-3,3-dimethyl-N-[2-[[(E)-3-methylsulfonylprop-2-enyl]amino]-2-oxoethyl]butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3354497; BDBM50042854
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[34] | |||
Compound Name |
(2S,3S)-2-N-[(2S)-1-[(2S)-2-[[(2S,3R)-1-Amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]-3-N-[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]oxirane-2,3-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3289843; BDBM50020426
Click to Show/Hide
|
||||
Activity |
Ki ~ 100000 nM
|
[9] | |||
Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382061; BDBM50491294
Click to Show/Hide
|
||||
Activity |
Ki = 100000 nM
|
[16] | |||
Compound Name |
5-((2,3-Dimethylphenoxy)methyl)-3-methyloxazolidin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL397973; SCHEMBL3958229; BDBM50201707; 5-[(2,3-dimethylphenoxy)methyl]-3-methyl-1,3-oxazolidin-2-one
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[39] | |||
Compound Name |
Benzyl N-[(2S,3R)-4-[acetyl(benzyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2179951; SCHEMBL17754419; BDBM50400263
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[40] | |||
Compound Name |
(3R,4R)-4-(2,3-Dimethylphenoxy)piperidin-3-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL230479; SCHEMBL3961271; BDBM50201706; trans-4-(2,3-dimethylphenoxy)-3-hydroxypiperidine
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[39] | |||
Compound Name |
4-Fluoro-2',4'-dihydroxychalcone
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|
Investigative | Compound Info | ||
Synonyms |
CHEMBL1928752; BDBM50491467; (e)-1-(2,4-dihydroxyphenyl)-3-(4-fluorophenyl)prop-2-en-1-one
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[20] | |||
Compound Name |
(2R,3R)-2-N-[(2S)-1-[(2S)-2-[[(2S,3R)-1-Amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]-3-N-[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]oxirane-2,3-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3290112; BDBM50020436
Click to Show/Hide
|
||||
Activity |
Ki ~ 100000 nM
|
[9] | |||
Compound Name |
3-[2-(3,5-Dichlorophenyl)-2-methylpropanoyl]-4-methoxy-N-[2-[[(E)-3-methylsulfonylprop-2-enyl]amino]-2-oxoethyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3354496; BDBM50042855
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[34] | |||
Compound Name |
Diethylcyanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
N,N-Diethylcyanamide; CYANAMIDE, DIETHYL-; N-Cyanodiethylamine; Diethylkyanamid; USAF EK-6326; Diethyl-cyanamide; MFCD00001769; CHEMBL274120; aminodiethylcarbonitrile; Diethylcyanamide, 99+%; Diethylkyanamid [Czech]; cyanodiethylamine; (Diethylamino)carbonitrile; NSC 7768; EINECS 210-532-7; BRN 1741595; NSC7768; Diethylcyanamide, 99%; cyanamide, N,N-diethyl-; ACMC-1B2S1; 4-04-00-00381 (Beilstein Handbook Reference); WLN: NCN2&2; CTK2F3540; DTXSID20210705; ALBB-025897; NSC-7768; ZINC1688361; BDBM50095484; SBB060416; AKOS015915817; MCULE-5340167535; AS-56776; D4965; R1024; ST45029069; J-802191
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[32] | |||
Compound Name |
(2E)-3-(3-Bromo-4-methoxyphenyl)-1-(4-fluorophenyl)prop-2-EN-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382057; ZINC7058678; BDBM50491471
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[20] | |||
Compound Name |
N-[2-(Cyanomethylamino)-2-oxoethyl]-3-[2-(3,5-dichlorophenyl)-2-methylpropanoyl]-4-[2-(dimethylamino)ethoxy]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3354493; BDBM50042858
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[34] | |||
Compound Name |
(2S,3S)-2-N-[(2S)-1-[[(2S)-5-Amino-1-[(2S)-2-[(2S)-2-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-1,5-dioxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]-3-N-[(2S)-1-[(2S)-2-[[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]oxirane-2,3-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3289847; BDBM50020430
Click to Show/Hide
|
||||
Activity |
Ki ~ 100000 nM
|
[9] | |||
Compound Name |
(2R,3R)-3-N-[(2S)-1-[(2S)-2-[[(2S,3R)-1-Amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]-2-N-[(2S)-1-[[(2S)-1-[(2S)-2-[(2S)-2-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]oxirane-2,3-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3290114; BDBM50020438
Click to Show/Hide
|
||||
Activity |
Ki ~ 100000 nM
|
[9] | |||
Compound Name |
(3S)-3-Acetamido-4-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[[(3S)-1-(benzylamino)-1,2-dioxohexan-3-yl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2370179; BDBM50071966
Click to Show/Hide
|
||||
Activity |
IC50 = 100000 nM
|
[41] | |||
Compound Name |
(E)-3-(3-Bromo-4-methoxyphenyl)-1-thiophen-2-ylprop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382058; BDBM50491470
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[20] | |||
Compound Name |
(2S)-2-(3,5-Dichlorophenyl)-N-[(3S)-1-[2-[[(E)-3-methylsulfonylprop-2-enyl]amino]-2-oxoethyl]-2-oxopyrrolidin-3-yl]butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3354499; BDBM50042851
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[34] | |||
Compound Name |
(2S,3S)-3-N-[(2S)-1-[(2S)-2-[[(2S,3R)-1-Amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]-2-N-[(2S)-1-[[(2S)-1-[(2S)-2-[(2S)-2-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]oxirane-2,3-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3289846; BDBM50020429
Click to Show/Hide
|
||||
Activity |
Ki ~ 100000 nM
|
[9] | |||
Compound Name |
(3S,4R)-4-(2,3-Dimethylphenoxy)piperidin-3-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL441907; SCHEMBL3959125; BDBM50201704; (3S,4R)-4-(2,3-Dimethylphenoxy)-3-piperidinol; UNII-LHH887104B component ZHFIAFNZGWCLHU-WCQYABFASA-N
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[39] | |||
Compound Name |
N-[2-(Cyanomethylamino)-2-oxoethyl]-3-[2-(3,5-dichlorophenyl)-2-methylpropanoyl]-4-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3354492; BDBM50042850
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[34] | |||
Compound Name |
N~2~-1,3-Benzoxazol-2-YL-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]ethyl}-L-alaninamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL204785; SCHEMBL5361355; BDBM19614; Heterocyclic arylaminoethyl amide, 3; DB07839; Q27097048
Click to Show/Hide
|
||||
Activity |
Ki ~ 100000 nM
|
[42] | |||
Compound Name |
Arylaminoethyl amide, 20
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL198450; BDBM19582
Click to Show/Hide
|
||||
Activity |
Ki ~ 100000 nM
|
[42] | |||
Compound Name |
(2E)-3-(4-Fluorophenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL8102; (E)-3-(4-fluorophenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one; 4-fluoro-4'-hydroxychalcone; SCHEMBL3004968; ZINC5094118; BDBM50491480; AKOS001032442; JS-2988; NCGC00331493-01; ST45113617; AB01325492-02; AB01325492-03; SR-01000227962; SR-01000227962-1; (E)-1-(4-Hydroxyphenyl)-3-(4-fluorophenyl)-2-propene-1-one
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[20] | |||
Compound Name |
(E)-3-(3-Bromo-4-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382054; BDBM50491477; AKOS008685465
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[20] | |||
Compound Name |
(2R,3R)-2-N-[(2S)-1-[[(2S)-5-Amino-1-[(2S)-2-[(2S)-2-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-1,5-dioxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]-3-N-[(2S)-1-[(2S)-2-[[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]oxirane-2,3-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3290115; BDBM50020439
Click to Show/Hide
|
||||
Activity |
Ki ~ 100000 nM
|
[9] | |||
Compound Name |
(2S)-N-[(2S)-1-Amino-4-methylsulfanyl-1-oxobutan-2-yl]-4-methyl-2-[[(1S)-2,2,2-trifluoro-1-[4-(4-methylsulfonylphenyl)phenyl]ethyl]amino]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL401176; SCHEMBL3814800; BDBM50214539
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[38] | |||
Compound Name |
1-[3-[(2Z)-3,7-Dimethylocta-2,6-dienyl]-2,4,6-trihydroxyphenyl]-3-(4-hydroxyphenyl)propan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3360923; BDBM50032157
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[43] | |||
Compound Name |
(2S)-2-[[(2S)-2-(3,5-Dichlorophenyl)-2-(ethylamino)acetyl]amino]-3,3-dimethyl-N-[2-[[(E)-3-methylsulfonylprop-2-enyl]amino]-2-oxoethyl]butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3354498; BDBM50042852
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[34] | |||
Compound Name |
(E)-3-(4-Fluorophenyl)-1-(2-hydroxy-4-methoxyphenyl)prop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2148111; ZINC4279051; BDBM50491466; STK788253; AKOS002164039; MCULE-6619799912; VU0488971-1; F1190-0598; 3-(4-fluorophenyl)-1-(2-hydroxy-4-methoxyphenyl)prop-2-en-1-one; (2E)-3-(4-fluorophenyl)-1-(2-hydroxy-4-methoxyphenyl)prop-2-en-1-one; (E)-3-(4-fluorophenyl)-1-(2-hydroxy-4-methoxyphenyl)-2-propen-1-one
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[20] | |||
Compound Name |
(2R,3R)-2-N-[(2S)-1-[(2S)-2-[[(2S,3R)-1-Amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]-3-N-[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]oxirane-2,3-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3290110; BDBM50020434
Click to Show/Hide
|
||||
Activity |
Ki ~ 100000 nM
|
[9] | |||
Compound Name |
(E)-3-(3-Bromo-4-methoxyphenyl)-1-(2,4-dihydroxyphenyl)prop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382055; BDBM50491482
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[20] | |||
Compound Name |
N-{(1S)-2,2,2-Trifluoro-1-[4'-(methylsulfonyl)biphenyl-4-yl]ethyl}-L-leucylglycinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL401175; SCHEMBL4205509; BDBM50214537
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[38] | |||
Compound Name |
(E)-3-(3-Bromo-4-methoxyphenyl)-1-(2-hydroxy-4-methoxyphenyl)prop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382056; BDBM50491476
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[20] | |||
Compound Name |
1-(5,7-Dihydroxy-2,2-dimethyl-3,4-dihydrochromen-6-yl)-3-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]propan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3352911; BDBM50032226
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[43] | |||
Compound Name |
(2S,3S)-2-N-[(2S,3R)-1-[(2S)-2-[[(2S,3R)-1-Amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl]-3-N-[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]oxirane-2,3-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3289842; BDBM50020425
Click to Show/Hide
|
||||
Activity |
Ki ~ 100000 nM
|
[9] | |||
Compound Name |
(E)-3-(4-Fluorophenyl)-1-(4-hydroxy-2-methoxyphenyl)prop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382115; BDBM50491479
Click to Show/Hide
|
||||
Activity |
IC50 ~ 100000 nM
|
[20] | |||
Compound Name |
S-Cyclohexyl cyclohexane-1-sulfinothioate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL1224169; BDBM50325649; S-cyclohexyl cyclohexanesulfinothioate; Cyclohexanethiosulfinic acid S-cyclohexyl ester
Click to Show/Hide
|
||||
Activity |
Ki ~ 100000 nM
|
[44] | |||
Compound Name |
2-[4-[[(3S)-3-Cyano-3-[[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]propoxy]methyl]triazol-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3805078; BDBM50168942
Click to Show/Hide
|
||||
Activity |
Ki = 101000 nM
|
[3] | |||
Compound Name |
2-[(3-Chlorophenyl)sulfanylmethyl]-N-(cyanomethyl)cyclohexane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2037484
Click to Show/Hide
|
||||
Activity |
IC50 = 102000 nM
|
[45] | |||
Compound Name |
Chembl4226557
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460491
Click to Show/Hide
|
||||
Activity |
Ki = 102000 nM
|
[29] | |||
Compound Name |
5-Nitro-8-(4-methylpiperidino)quinoline
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2312204; MDK0734; 8-(4-methylpiperidin-1-yl)-5-nitroquinoline; BDBM50425024
Click to Show/Hide
|
||||
Activity |
Ki = 105000 nM
|
[24] | |||
Compound Name |
N,N-Diethyl-1-(5-nitroquinoline-8-yl)piperidine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2312206; BDBM50425012
Click to Show/Hide
|
||||
Activity |
Ki = 105000 nM
|
[24] | |||
Compound Name |
(2S,4R)-1-(2-Nitro-phenyl)-4-(2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic acid [(S)-1-(benzooxazole-2-carbonyl)-propyl]-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3649366; BDBM122475; US8729061, 5
Click to Show/Hide
|
||||
Activity |
IC50 = 105500 nM
|
[46] | |||
Compound Name |
[(S)-1-(Pyridin-2-ylaminooxalyl)-pentyl]-carbamic acid (S)-2,2-dimethyl-1-[3-(4-trifluoromethyl-phenyl)-pyrazol-1-ylmethyl]-propyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL188929; SCHEMBL8371501; BDBM50169485
Click to Show/Hide
|
||||
Activity |
IC50 = 107000 nM
|
[21] | |||
Compound Name |
Chembl4227299
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460499
Click to Show/Hide
|
||||
Activity |
Ki = 109000 nM
|
[29] | |||
Compound Name |
N-[(2S)-1-[5-(Furan-2-yl)-1,3,4-oxadiazol-2-yl]-1-oxopentan-2-yl]-2-phenylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL209294; BDBM50410970
Click to Show/Hide
|
||||
Activity |
Ki = 110000 nM
|
[47] | |||
Compound Name |
(4As,10R,10aR)-8-(5-chloropyridin-3-yl)-4a-methylspiro[2,3,4,10a-tetrahydropyrano[3,2-b]chromene-10,4'-5H-1,3-oxazole]-2'-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3357665; SCHEMBL9933110; BDBM50033399
Click to Show/Hide
|
||||
Activity |
IC50 = 110000 nM
|
[23] | |||
Compound Name |
Benzyl 1-((cyanomethyl)carbamoyl)cyclopentylcarbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL372140; SCHEMBL6183581; Benzyl N-[1-(cyanomethylcarbamoyl)cyclopentyl]carbamate; BDBM50410577
Click to Show/Hide
|
||||
Activity |
Ki = 110000 nM
|
[4] | |||
Compound Name |
Benzyl N-[(2S)-4-methyl-1-[[4-[3-(4-methylpiperazin-1-yl)propylamino]-3,4-dioxo-1-phenylbutan-2-yl]amino]-1-oxopentan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL1240876; BDBM50326307; 3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(4-methylpiperazin-1-yl)propyl)-2-oxophenylbutanamide
Click to Show/Hide
|
||||
Activity |
Ki = 111000 nM
|
[33] | |||
Compound Name |
4-Nitro-1-naphthylamine
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
4-nitronaphthalen-1-amine; 1-Amino-4-nitronaphthalene; 1-Naphthalenamine, 4-nitro-; 1-NAPHTHYLAMINE, 4-NITRO-; 1,4-Nitronaphthylamine; 4-Nitro-1-naphthamine; 4-Nitro-naphthalen-1-ylamine; 4-Nitro-1-naphthalenamine; 4-nitronaphthylamine; NSC 614; 4-Nitro-.alpha.-naphthylamine; (4-nitro-1-naphthyl)amine; CHEMBL2312201; 4-Nitro-alpha-naphthylamine; EINECS 212-277-7; BRN 2211897; AI3-62662; NSC614; ACMC-1BEIO; 4-nitro-1-naphthalamine; 1-Naphthalenamine,4-nitro-; 4-12-00-03114 (Beilstein Handbook Reference); SCHEMBL297029; 4-Nitro-1-naphthylamine, 97%; CTK5E4722; DTXSID60228263; NSC-614; ACN-S002777; ALBB-024928; BCP04287; KS-00000G4T; STR04258; ZINC4284753; ANW-37066; BBL002074; BDBM50425019; MFCD00004026; SBB052081; STK803079; AKOS005609791; MCULE-2930512718; PS-4372; AC-29187; AK-96682; SC-45861; AB0007456; DB-056235; FT-0607331; N0213; R1086; ST45028057; 776N341; A839149; AG-205/01843055
Click to Show/Hide
|
||||
Activity |
Ki = 111000 nM
|
[24] | |||
Compound Name |
1-(5-Nitroquinoline-8-yl)piperidine-4-carboxylic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2312205; BDBM50425023
Click to Show/Hide
|
||||
Activity |
Ki = 113000 nM
|
[24] | |||
Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-3-[4-(4-methylphenyl)phenyl]-1-oxopropan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382003; BDBM50491284
Click to Show/Hide
|
||||
Activity |
Ki = 113000 nM
|
[16] | |||
Compound Name |
(2R,3R)-Dibenzyl 1-((S)-1-((S)-2-(tert-butoxycarbonyl)-4-methylpentanoyl)pyrrolidine-5-carbonyl)aziridine-2,3-dicarboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL383647; BDBM50183767
Click to Show/Hide
|
||||
Activity |
Ki = 114000 nM
|
[48] | |||
Compound Name |
Chembl4227750
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460488
Click to Show/Hide
|
||||
Activity |
Ki = 116000 nM
|
[29] | |||
Compound Name |
7-[[(2R)-2-Methylpiperidin-1-yl]methyl]-5-nitroquinolin-8-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2312217; BDBM50425029
Click to Show/Hide
|
||||
Activity |
Ki = 116000 nM
|
[24] | |||
Compound Name |
8-Hydroxy-5-nitroquinoline-7-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2312221; BDBM50425015
Click to Show/Hide
|
||||
Activity |
Ki = 117000 nM
|
[24] | |||
Compound Name |
Chembl4227143
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460505
Click to Show/Hide
|
||||
Activity |
Ki = 118000 nM
|
[29] | |||
Compound Name |
[(S)-1-((S)-3-Benzyloxy-2-oxo-1-phenethyl-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL100428; BDBM50119066
Click to Show/Hide
|
||||
Activity |
Ki = 119000 nM
|
[49] | |||
Compound Name |
Tert-butyl N-[(2S)-1-oxo-1-(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)pentan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL210315; BDBM50410972
Click to Show/Hide
|
||||
Activity |
Ki = 120000 nM
|
[47] | |||
Compound Name |
2-((2S,3S)-2-Acetoxy-4-oxo-azetidin-3-ylcarbamoyl)-pyrrolidine-1-carboxylic acid benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL411932; BDBM50129078
Click to Show/Hide
|
||||
Activity |
Ki = 120000 nM
|
[18] | |||
Compound Name |
Chembl4226694
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460484
Click to Show/Hide
|
||||
Activity |
Ki = 121000 nM
|
[29] | |||
Compound Name |
Chembl4227268
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460487
Click to Show/Hide
|
||||
Activity |
Ki = 122000 nM
|
[29] | |||
Compound Name |
Chembl4228576
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460502
Click to Show/Hide
|
||||
Activity |
Ki = 124000 nM
|
[29] | |||
Compound Name |
(1R,2S)-2-[(8-Hydroxy-5-nitroquinolin-7-yl)methylamino]cyclohexane-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2312220; BDBM50425016
Click to Show/Hide
|
||||
Activity |
Ki = 125000 nM
|
[24] | |||
Compound Name |
N-Benzyl-5-nitroquinolin-8-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2312207; Oprea1_431051; (5-nitro(8-quinolyl))benzylamine; N-Benzyl-5-nitroquinoline-8-amine; ZINC3880717; BDBM50425022; STK035463; AKOS000424016; MCULE-9246113308; NCGC00324553-01; EU-0043808; ST50011640; AB01225531-03
Click to Show/Hide
|
||||
Activity |
Ki = 127000 nM
|
[24] | |||
Compound Name |
Chembl4227676
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460509
Click to Show/Hide
|
||||
Activity |
Ki = 128000 nM
|
[29] | |||
Compound Name |
N-[(2S)-1-[[(2S)-1,6-Diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2,3,4,5,6-pentafluorobenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382072; BDBM50491320
Click to Show/Hide
|
||||
Activity |
Ki = 134000 nM
|
[16] | |||
Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382062; BDBM50491293
Click to Show/Hide
|
||||
Activity |
Ki = 135000 nM
|
[16] | |||
Compound Name |
(2S)-6-Amino-2-[[(2S)-2-[3-(4-hydroxyphenyl)propanoylamino]-3-phenylpropanoyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382079; BDBM50491292
Click to Show/Hide
|
||||
Activity |
Ki = 135000 nM
|
[16] | |||
Compound Name |
N-Methyl-N-benzyl-5-nitroquinoline-8-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2312208; BDBM50425014
Click to Show/Hide
|
||||
Activity |
Ki = 137000 nM
|
[24] | |||
Compound Name |
Chembl4225182
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460508; ZINC584651169
Click to Show/Hide
|
||||
Activity |
Ki = 139000 nM
|
[29] | |||
Compound Name |
[1-((3S,4S)-2-Oxo-4-phenoxy-azetidin-3-ylcarbamoyl)-cyclohexyl]-carbamic acid benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL64612; BDBM50129073
Click to Show/Hide
|
||||
Activity |
Ki = 140000 nM
|
[18] | |||
Compound Name |
6-Amino-N-[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382074; BDBM50491286
Click to Show/Hide
|
||||
Activity |
Ki = 148000 nM
|
[16] | |||
Compound Name |
Tert-butyl N-[(2S)-1-[5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-1-oxopentan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL378780; BDBM50410969
Click to Show/Hide
|
||||
Activity |
Ki ~ 150000 nM
|
[47] | |||
Compound Name |
Tert-butyl N-[(2S)-1-[5-[4-(dimethylamino)phenyl]-1,3,4-oxadiazol-2-yl]-1-oxopentan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL210523; BDBM50410974
Click to Show/Hide
|
||||
Activity |
Ki ~ 150000 nM
|
[47] | |||
Compound Name |
[(S)-1-((S)-3-Ethoxy-2-oxo-1-phenethyl-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL327290; BDBM50119064
Click to Show/Hide
|
||||
Activity |
Ki ~ 150000 nM
|
[49] | |||
Compound Name |
Benzyl N-[(2R)-1-(cyanomethylamino)-4-methyl-1-oxopentan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL200511; BDBM50410573
Click to Show/Hide
|
||||
Activity |
Ki ~ 150000 nM
|
[4] | |||
Compound Name |
Ac-hPhe-Leu-(D)-Ala-LeuVSMe
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL438442; BDBM50186701
Click to Show/Hide
|
||||
Activity |
IC50 ~ 150000 nM
|
[1] | |||
Compound Name |
Cbz-Glu(OtBu)-Gly-LeuVSMe
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL208019; BDBM50186695
Click to Show/Hide
|
||||
Activity |
IC50 ~ 150000 nM
|
[1] | |||
Compound Name |
Benzyl N-[(2S)-1-(cyanomethylamino)-5,5,5-trifluoro-4-methyl-1-oxopentan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL372977; BDBM50410598
Click to Show/Hide
|
||||
Activity |
Ki ~ 150000 nM
|
[4] | |||
Compound Name |
Benzyl N-[(2S)-1-(cyanomethylamino)-1-oxohexan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL200531; BDBM50410585
Click to Show/Hide
|
||||
Activity |
Ki ~ 150000 nM
|
[4] | |||
Compound Name |
Cbz-Ile-iPrGln-Ala-LeuVSMe
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL437115; BDBM50186711
Click to Show/Hide
|
||||
Activity |
IC50 ~ 150000 nM
|
[1] | |||
Compound Name |
Tert-butyl N-[(2S)-1-oxo-1-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pentan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL209766; BDBM50410975
Click to Show/Hide
|
||||
Activity |
Ki ~ 150000 nM
|
[47] | |||
Compound Name |
Benzyl (2S,3S)-1-((R)-3-(benzylsulfonyl)-1-((S)-1-((S,E)-5-methyl-1-(methylsulfonyl)hex-1-en-3-ylamino)-1-oxopropan-2-ylamino)-1-oxopropan-2-ylamino)-3-methyl-1-oxopentan-2-ylcarbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL377123; BDBM50186723
Click to Show/Hide
|
||||
Activity |
IC50 ~ 150000 nM
|
[1] | |||
Compound Name |
Benzyl 1-((cyanomethyl)carbamoyl)cyclopropylcarbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL200776; SCHEMBL6181261; Benzyl N-[1-(cyanomethylcarbamoyl)cyclopropyl]carbamate; BDBM50410599
Click to Show/Hide
|
||||
Activity |
Ki ~ 150000 nM
|
[4] | |||
Compound Name |
Benzyl N-[(2S)-1-(cyanomethylamino)-3,3-dimethyl-1-oxobutan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL199483; BDBM50410581
Click to Show/Hide
|
||||
Activity |
Ki ~ 150000 nM
|
[4] | |||
Compound Name |
Benzyl N-[(2S)-1-(cyanomethylamino)-3-hydroxy-1-oxobutan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL371059; BDBM50410613
Click to Show/Hide
|
||||
Activity |
Ki ~ 150000 nM
|
[4] | |||
Compound Name |
Methyl (E)-4-[[2-[(3R)-5-(4-bromophenyl)-3-[[4-chloro-2-(trifluoromethyl)phenyl]carbamoyloxymethyl]-2-oxo-3H-1,4-benzodiazepin-1-yl]acetyl]amino]but-2-enoate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL1171633; BDBM50322343
Click to Show/Hide
|
||||
Activity |
Ki ~ 150000 nM
|
[50] | |||
Compound Name |
[1-((3S,4R)-2-Oxo-4-phenoxy-azetidin-3-ylcarbamoyl)-cyclohexyl]-carbamic acid benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL64245; BDBM50129072
Click to Show/Hide
|
||||
Activity |
Ki ~ 150000 nM
|
[18] | |||
Compound Name |
Disodium aurothiomalate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
disodium [2-(sulfanyl-kappaS)butanedioato(3-)]aurate(2-); aurothiomalate dianion; CHEMBL182346; BDBM50153289
Click to Show/Hide
|
||||
Activity |
IC50 = 150000 nM
|
[51] | |||
Compound Name |
Ptosyl-NeopentylAsn-Ser-LeuVSMe
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL204946; BDBM50186707
Click to Show/Hide
|
||||
Activity |
IC50 ~ 150000 nM
|
[1] | |||
Compound Name |
Benzyl N-[(2S)-1-(cyanomethylamino)-2,4-dimethyl-1-oxopentan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL200545; BDBM50410604
Click to Show/Hide
|
||||
Activity |
Ki ~ 150000 nM
|
[4] | |||
Compound Name |
Benzyl N-[(1S)-2-(cyanomethylamino)-2-oxo-1-phenylethyl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL200775; BDBM50410586
Click to Show/Hide
|
||||
Activity |
Ki ~ 150000 nM
|
[4] | |||
Compound Name |
[(S)-1-((S)-3-Methoxy-2-oxo-1-phenethyl-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL100095; SCHEMBL7764593; BDBM50119067
Click to Show/Hide
|
||||
Activity |
Ki ~ 150000 nM
|
[49] | |||
Compound Name |
8-(Morpholin-4-yl)-5-nitroquinoline
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
4-(5-nitroquinolin-8-yl)morpholine; CHEMBL2312224; Oprea1_106135; 5-Nitro-8-morpholinoquinoline; CTK4G5308; DTXSID40385247; ZINC3877851; BDBM50425025; STK067115; AKOS000425733; MCULE-8212134508; Quinoline,8-(4-morpholinyl)-5-nitro-; SR-01000196683; SR-01000196683-1
Click to Show/Hide
|
||||
Activity |
Ki = 153000 nM
|
[24] | |||
Compound Name |
Chembl4227036
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460495
Click to Show/Hide
|
||||
Activity |
Ki = 154000 nM
|
[29] | |||
Compound Name |
Chembl4224831
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460504; N-benzyl-N-(cyanomethyl)-8-hydroxy-5-nitroquinoline-2-carboxamide
Click to Show/Hide
|
||||
Activity |
Ki = 156000 nM
|
[29] | |||
Compound Name |
Chembl4225905
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460500
Click to Show/Hide
|
||||
Activity |
Ki = 160000 nM
|
[29] | |||
Compound Name |
Chembl4249139
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50463231
Click to Show/Hide
|
||||
Activity |
IC50 = 160000 nM
|
[26] | |||
Compound Name |
Chembl4228513
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460486
Click to Show/Hide
|
||||
Activity |
Ki = 168000 nM
|
[29] | |||
Compound Name |
Pyrrolidine, 1-(4-nitro-1-naphthalenyl)-
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL570897; 1-(4-nitronaphthalen-1-yl)pyrrolidine; ACMC-20mc9g; (4-nitronaphthyl)pyrrolidine; Oprea1_221230; SCHEMBL3603749; CTK0D5811; DTXSID10403220; 1-(4-nitro-1-naphthyl)pyrrolidine; ZINC4126409; BDBM50415097; AKOS001483561; MCULE-7970978795; EU-0066932; ST50993708; SR-01000390159; SR-01000390159-1
Click to Show/Hide
|
||||
Activity |
Ki = 170000 nM
|
[24] | |||
Compound Name |
5-Nitro-7-[[4-(pyridin-3-ylmethyl)piperazin-1-yl]methyl]quinolin-8-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2312210; BDBM50425035
Click to Show/Hide
|
||||
Activity |
Ki = 171000 nM
|
[24] | |||
Compound Name |
Chembl4227015
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460501
Click to Show/Hide
|
||||
Activity |
Ki = 171000 nM
|
[29] | |||
Compound Name |
(3S)-3-Acetamido-4-[[(2R)-1-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[[(3S)-1-(benzylamino)-1,2-dioxohexan-3-yl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2370184; BDBM50071968
Click to Show/Hide
|
||||
Activity |
IC50 = 172000 nM
|
[41] | |||
Compound Name |
N-Methyl-N-phenethyl-5-nitroquinoline-8-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2312199; BDBM50425020
Click to Show/Hide
|
||||
Activity |
Ki = 175000 nM
|
[24] | |||
Compound Name |
(2-Hydroxy-5-nitrophenyl)(morpholino)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL4227257; BDBM50460489
Click to Show/Hide
|
||||
Activity |
Ki = 176000 nM
|
[29] | |||
Compound Name |
N-[[1-(1,3-Benzothiazol-2-ylmethyl)piperidin-4-yl]methyl]-8-hydroxy-N-(2-methoxyethyl)-5-nitroquinoline-7-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3593652; BDBM50096251
Click to Show/Hide
|
||||
Activity |
Ki = 181000 nM
|
[29] | |||
Compound Name |
Chembl4228606
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460479
Click to Show/Hide
|
||||
Activity |
Ki = 190000 nM
|
[29] | |||
Compound Name |
Chembl4226671
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460482
Click to Show/Hide
|
||||
Activity |
Ki = 192000 nM
|
[29] | |||
Compound Name |
3-[4-[[(3S)-3-Cyano-3-[[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]propoxy]methyl]triazol-1-yl]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3805060; BDBM50168945
Click to Show/Hide
|
||||
Activity |
Ki = 196000 nM
|
[3] | |||
Compound Name |
2,2',4-Trihydroxybenzophenone
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
1,1,3-Trihydroxybenzophenone; CHEMBL470701; (2,4-dihydroxyphenyl)-(2-hydroxyphenyl)methanone; Methanone, (2,4-dihydroxyphenyl)(2-hydroxyphenyl)-; Benzophenone, 2,2',4-trihydroxy-; SCHEMBL93207; 2,2'',4-trihydroxybenzophenone; CTK0F5619; DTXSID70342106; ZINC136125; BDBM50249353; AKOS022657180; MCULE-9477407393; ST029236; 2,4-dihydroxyphenyl 2-hydroxyphenyl ketone; (2,4-Dihydroxyphenyl)(2-hydroxyphenyl)methanone #
Click to Show/Hide
|
||||
Activity |
IC50 = 198000 nM
|
[52] | |||
Click to Show/Hide the Information of All Poor Binders |
Non Binders of This Target (in total, 75 non binders) | Download | Top | |||
---|---|---|---|---|---|
Compound Name |
dibutyl phthalate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
di-n-butyl phthalate; n-butyl phthalate; nutyl phthalate
Click to Show/Hide
|
||||
Activity |
IC50 = 420000 nM
|
[53] | |||
Compound Name |
(4Ar,10S,10aS)-8-(2-fluoropyridin-3-yl)spiro[3,4,4a,10a-tetrahydro-2H-pyrano[3,2-b]chromene-10,4'-5H-1,3-thiazole]-2'-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3357663; BDBM50033401
Click to Show/Hide
|
||||
Activity |
IC50 > 200000 nM
|
[23] | |||
Compound Name |
(4As,10R,10aR)-4a-methyl-8-pyrimidin-5-ylspiro[2,3,4,10a-tetrahydropyrano[3,2-b]chromene-10,4'-5H-1,3-oxazole]-2'-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL3357671; SCHEMBL9882534; BDBM50033412
Click to Show/Hide
|
||||
Activity |
IC50 > 200000 nM
|
[23] | |||
Compound Name |
Chembl4224754
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460490
Click to Show/Hide
|
||||
Activity |
Ki = 202000 nM
|
[29] | |||
Compound Name |
4-Benzylsulfanyl-6-(cyclopropylmethylsulfanyl)-1H-1,3,5-triazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL1836516; BDBM50354249
Click to Show/Hide
|
||||
Activity |
Ki = 211500 nM
|
[17] | |||
Compound Name |
2-Bromo-4-nitronaphthalen-1-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
2-Bromo-4-nitro-1-naphthalenamine; 2-Bromo-4-nitro-naphthalen-1-ylamine; 2-Bromo-4-nitro-1-naphthylamine; CHEMBL2312203; MFCD00085870; 2-bromo-4-nitro-1-aminonaphthalene; SCHEMBL3609722; CTK2A9597; DTXSID70629368; 1-Amino-2-Bromo-4-nitronaphthalene; 1606AJ; BDBM50425017; ZINC95595255; 1-Naphthalenamine, 2-bromo-4-nitro-; ACN-047841; SB38041; AS-62816; SY129737; CS-0103519; W-3987
Click to Show/Hide
|
||||
Activity |
Ki = 212000 nM
|
[24] | |||
Compound Name |
Chembl4225141
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460498
Click to Show/Hide
|
||||
Activity |
Ki = 224000 nM
|
[29] | |||
Compound Name |
(S)-2-[(S)-2-(3,3-Dimethyl-butanoylamino)-3,3-dimethyl-butanoylamino]-N4,N4-dimethyl-N1-[1-methyl-2-(6-methyl-benzoxazol-2-yl)-2-oxo-ethyl]-succinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL424452; SCHEMBL6560414; BDBM50061528
Click to Show/Hide
|
||||
Activity |
IC50 = 225000 nM
|
[25] | |||
Compound Name |
Ethyl 2-methyl-4,4-diphenylbuta-2,3-dienoate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL443611; SCHEMBL8638044; CTK1F2738; DTXSID80550351; BDBM50292631; 2-Methyl-4,4-diphenyl-2,3-butadienoic acid ethyl ester; 2,3-Butadienoic acid, 2-methyl-4,4-diphenyl-, ethyl ester; alpha-methyl-gamma,gamma-diphenylallenecarboxylic acid ethyl ester
Click to Show/Hide
|
||||
Activity |
IC50 = 232000 nM
|
[54] | |||
Compound Name |
Chembl4228921
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
BDBM50460493
Click to Show/Hide
|
||||
Activity |
Ki = 237000 nM
|
[29] | |||
Compound Name |
Cbz-Phe-[Gly-trans epoxy-Gly]-Ala-AlaOMe
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL500638; BDBM50265073
Click to Show/Hide
|
||||
Activity |
Ki = 244000 nM
|
[37] | |||
Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-3-[4-(2-methylphenyl)phenyl]-1-oxopropan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382002; BDBM50491299
Click to Show/Hide
|
||||
Activity |
Ki = 245000 nM
|
[16] | |||
Compound Name |
Ridaura
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
AURANOFIN; Triethylphosphine gold; SK&F-39162; SK-39162; 2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold; Auranofina; Auranofine; Auranofinum; Auroafen; CHEMBL1366; GTPL6306; BDBM50153291; DB00995; (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold2,3,4,6-tetraacetate
Click to Show/Hide
|
||||
Activity |
IC50 = 250000 nM
|
[51] | |||
Compound Name |
4-Benzylsulfanyl-6-propylsulfanyl-1H-1,3,5-triazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL1836512; BDBM50354250
Click to Show/Hide
|
||||
Activity |
Ki = 259000 nM
|
[17] | |||
Compound Name |
4-Bromo-N-[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2382068; BDBM50491306
Click to Show/Hide
|
||||
Activity |
Ki = 261000 nM
|
[16] | |||
Compound Name |
(3S)-2-[(2S)-2-[[(2S)-2-Cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-N-[1,2-dioxo-1-[[(1R)-1-phenylethyl]amino]hexan-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL184035; BDBM50152751
Click to Show/Hide
|
||||
Activity |
Ki = 283000 nM
|
[55] | |||
Compound Name |
Benzophenone
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
diphenylmethanone; Diphenyl ketone; Methanone, diphenyl-; Benzoylbenzene; Phenyl ketone; Ketone, diphenyl; alpha-Oxoditane; Benzene, benzoyl-; alpha-Oxodiphenylmethane; Diphenylketone; diphenyl-methanone; Kayacure bp; Diphenyl-methanon; NSC 8077; .alpha.-Oxoditane; UNII-701M4TTV9O; Adjutan 6016; MFCD00003076; .alpha.-Oxodiphenylmethane; CHEMBL90039; 701M4TTV9O; DTXSID0021961; FEMA 2134; NCGC00090787-05; DSSTox_CID_1961; Benzophenone, 99%, pure; Benzophenone, 99+%, pure; DSSTox_RID_76429; DSSTox_GSID_21961; Caswell No. 081G; CCRIS 629; FEMA No. 2134; HSDB 6809; WLN: RVR; EINECS 204-337-6; EPA Pesticide Chemical Code 000315; BENZOPHENONE (8CI); phenylketone; Benzopheneone; Benzophenon; benzophenone-; benzoyl-benzene; a-Oxoditane; AI3-00754; meta-benzophenone; alpha -oxoditane; Benzophenone Flakes; di(phenyl)methanone; a-Oxodiphenylmethane; METHANONE, DIPHENYL- (9CI); Ph2CO; Diphenylmethanone, 9CI; PubChem20909; ACMC-20aj4t; alpha -oxodiphenylmethane; Dimenhydrinate Impurity J; UPCMLD-DP071; EC 204-337-6; BIDD:PXR0008; SCHEMBL17745; KSC174M3P; MLS001055400; ADK STAB 1413; BIDD:ER0022; Benzophenone (diphenyl-ketone); Benzophenone (Diphenylmethanone); Diphenylmethanone (Benzophenone); UPCMLD-DP071:001; BDBM22726; Benzophenone, analytical standard; CTK0H4637; KS-00000VHW; TIMTEC-BB SBB040865; NSC8077; OTAVA-BB 1043895; HMS2268A24; LABOTEST-BB LTBB001874; ZINC968233; Benzophenone, >=99%, FCC, FG; HY-Y0546; NSC-8077; AKOS BBS-00004333; Tox21_113465; Tox21_202425; Tox21_300058; Benzophenone, ReagentPlus(R), 99%; SBB040865; STL363250; Benzophenone, for synthesis, 98.0%; AKOS000119029; Tox21_113465_1; AS01184; BENZOPHENONE (DIPHENYL-KETONE); DB01878; EBD2761160; MCULE-7496069620; NE10260; Benzophenone, purum, >=99.0% (GC); Benzophenone, ReagentPlus(R), >=99%; NCGC00090787-01; NCGC00090787-03; NCGC00090787-04; NCGC00090787-06; NCGC00090787-07; NCGC00090787-08; NCGC00254183-01; NCGC00259974-01; BP-21212; SC-65188; SMR000112143; Benzophenone, SAJ first grade, >=99.0%; DB-061602; B0083; CS-0015323; FT-0622720; FT-0693251; ST50214455; Benzophenone, purified by sublimation, >=99%; Benzophenone, Vetec(TM) reagent grade, 98%; C06354; Q409482; Q-200691; F0001-0309; Z1245792986; METTLER-TOLEDO(R) CALIBRATION SUBSTANCE ME 18870
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Activity |
IC50 = 288800 nM
|
[52] | |||
Compound Name |
(S)-N1-((S)-1-Benzyloxy-2-oxo-azetidin-3-yl)-2-[(S)-2-(3,3-dimethyl-butanoylamino)-3,3-dimethyl-butanoylamino]-N4,N4-dimethyl-succinamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL131760; BDBM50061504
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Activity |
IC50 > 300000 nM
|
[25] | |||
Compound Name |
(S)-2-[(S)-2-(3,3-Dimethyl-butanoylamino)-3,3-dimethyl-butanoylamino]-N4,N4-dimethyl-N1-[1-methyl-2-(4-methyl-benzoxazol-2-yl)-2-oxo-ethyl]-succinamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL133638; SCHEMBL6559638; BDBM50061511
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Activity |
IC50 > 300000 nM
|
[25] | |||
Compound Name |
(S)-2-[(S)-2-(3,3-Dimethyl-butanoylamino)-3,3-dimethyl-butanoylamino]-N4,N4-dimethyl-N1-[1-methyl-2-(5-methyl-benzoxazol-2-yl)-2-oxo-ethyl]-succinamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL133854; SCHEMBL6559309; BDBM50061509
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Activity |
IC50 > 300000 nM
|
[25] | |||
Compound Name |
(S)-2-[(S)-2-(3,3-Dimethyl-butanoylamino)-3,3-dimethyl-butanoylamino]-N4,N4-dimethyl-N1-(3,3,4,4,4-pentafluoro-1-methyl-2-oxo-butyl)-succinamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL134167; SCHEMBL6559675; BDBM50061518
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Activity |
IC50 > 300000 nM
|
[25] | |||
Compound Name |
(S)-2-[(S)-2-(3,3-Dimethyl-butanoylamino)-3,3-dimethyl-butanoylamino]-N4,N4-dimethyl-N1-[1-methyl-2-(7-methyl-benzoxazol-2-yl)-2-oxo-ethyl]-succinamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL134131; SCHEMBL6559677; BDBM50061497
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Activity |
IC50 > 300000 nM
|
[25] | |||
Compound Name |
(S)-N1-((S)-3-Benzylcarbamoyl-3,3-difluoro-1-methyl-2-oxo-propyl)-2-[(S)-2-(3,3-dimethyl-butanoylamino)-3,3-dimethyl-butanoylamino]-N4,N4-dimethyl-succinamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL335309; BDBM50061530
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Activity |
IC50 > 300000 nM
|
[25] | |||
Compound Name |
1-[[(2S)-4-(Dimethylamino)-2-[[(2S)-2-(3,3-dimethylbutanoylamino)-3,3-dimethylbutanoyl]amino]-4-oxobutanoyl]amino]ethyl-(diphenoxymethyl)-oxophosphanium
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Investigative | Compound Info | ||
Synonyms |
CHEMBL334303; BDBM50061516
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Activity |
IC50 > 300000 nM
|
[25] | |||
Compound Name |
(S)-2-{[(2S,4R)-1-((S)-2-{(S)-2-[(R)-2-((S)-2-Acetylamino-3-carboxy-propionylamino)-4-carboxy-butyrylamino]-2-cyclohexyl-acetylamino}-3-methyl-butyryl)-4-(naphthalen-2-ylmethoxy)-pyrrolidine-2-carbonyl]-amino}-pentanoic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL432156; BDBM50093010; Ac-D-CyclohexylGly-V-Naphthenylmethoxypro-Nva-OH; Ac-Asp-D-Glu-Cyclohexylglycine-Val-[(4R)-naphthenylmethoxyproline]-Norvaline-OH; Ac-L-Asp-D-Glu-[(S)-2-Cyclohexyl-Gly-]-L-Val-4beta-(2-naphthylmethoxy)-L-Pro-L-Nva-OH
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Activity |
IC50 > 300000 nM
|
[56] | |||
Compound Name |
(S)-2-((S)-2-(3,3-Dimethylbutanamido)-3,3-dimethylbutanamido)-N4,N4-dimethyl-N1-(4,4,4-trifluoro-3-oxobutan-2-yl)succinamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2370698; BDBM50061498
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Activity |
IC50 > 300000 nM
|
[25] | |||
Compound Name |
(S)-N1-(2-Benzylcarbamoyl-1-methyl-2-oxoethyl)-2-[(S)-2-(3,3-dimethyl-butanoylamino)-3,3-dimethyl-butanoylamino]-N4,N4-dimethylsuccinamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL422440; BDBM50061503
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Activity |
IC50 > 300000 nM
|
[25] | |||
Compound Name |
(S)-N1-(1-(Benzo[d]oxazol-2-yl)-1-oxopropan-2-yl)-2-((S)-2-(3,3-dimethylbutanamido)-3,3-dimethylbutanamido)-N4,N4-dimethylsuccinamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL131909; SCHEMBL6560446; BDBM50061512
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Activity |
IC50 > 300000 nM
|
[25] | |||
Compound Name |
N-[(2S)-1-[[(2S)-1,6-Diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]naphthalene-2-carboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382066; BDBM50491290
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Activity |
Ki = 301000 nM
|
[16] | |||
Compound Name |
4-Tert-butyl-N-[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]benzamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382063; BDBM50491289
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Activity |
Ki = 312000 nM
|
[16] | |||
Compound Name |
Chembl4228082
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Investigative | Compound Info | ||
Synonyms |
BDBM50460503
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Activity |
Ki = 322000 nM
|
[29] | |||
Compound Name |
Cbz-l-phenylalanyl-l-arginine amide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2381994; SCHEMBL5929274; BDBM50491298
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Activity |
Ki = 349000 nM
|
[16] | |||
Compound Name |
2-[(4-Benzylsulfanyl-6-oxo-1H-1,3,5-triazin-2-yl)sulfanyl]acetic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL1836515; BDBM50354253
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Activity |
Ki = 351000 nM
|
[17] | |||
Compound Name |
(2S,3S)-1,2-Epoxy-3-(Cbz-amino)-4-phenylbutane
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Investigative | Compound Info | ||
Synonyms |
CHEMBL298965; BENZYL N-[(1S)-1-[(2S)-OXIRAN-2-YL]-2-PHENYLETHYL]CARBAMATE; (1S,2S)-Cbz epoxide; 3(S)-(N-(benzyloxycarbonyl)amino]-1,2(S)-epoxy-4-phenylbutane; 3(S)-[N-(benzyloxycarbonyl)amino]-1,2(S)-epoxy-4-phenylbutane; SCHEMBL2575768; CTK4B5838; erythro-Cbz-phenylalanine epoxide; Carbamic acid,N-[(1S)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-, phenylmethyl ester; BCP25736; BDBM50284944; ZINC21982295; 018E440; N-Cbz-3-(S)-amino-1,2-(S)-epoxy-4-phenylbutane; 3(S)-(benzyloxyformamido)-1,2(S)-epoxy-4-phenylbutane; benzyl (1S)-1-[(2S)-oxiranyl]-2-phenylethylcarbamate; benzyl (S)-1-((S)-oxiran-2-yl)-2-phenylethyl-carbamate; N-benzyloxycarbonyl-3(S)-amino-1,2(S)epoxy-4-phenylbutane; N-benzyloxycarbonyl 3 (S)-amino-1,2-(S)-epoxy-4-phenylbutane; N-benzyloxycarbonyl 3(S)-amino-1,2-(S)-epoxy-4-phenylbutane; N-benzyloxycarbonyl-3 (S)-amino-1,2(S)-epoxy-4-phenylbutane; N-benzyloxycarbonyl-3(S)-amino-1,2 (S) -epoxy-4-phenylbutane; N-benzyloxycarbonyl-3(S)-amino-1,2(S)-epoxy-4- phenylbutane; N-benzyloxycarbonyl-3(S)-amino-1,2(S)-epoxy-4-phenylbutane; ((S)-1-(S)-Oxiranyl-2-phenyl-ethyl)-carbamic acid benzyl ester; 3(S)-[N-(benzyloxycarbonyl) amino]-1,2(S)-epoxy-4-phenylbutane; 3(S)-[N-(benzyloxycarbonyl)amino] -1,2(S) -epoxy-4-phenylbutane; 3(S)-[N-(benzyloxycarbonyl)amino]-1,2(S) -epoxy-4-phenylbutane; N-benzyloxycarbonyl-3 (S) -amino-1, 2 (S) -epoxy-4-phenylbutane; N-benzyloxycarbonyl-3 (S) -amino-1,2(s) -epoxy-4-phenylbutane
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Activity |
Ki = 367000 nM
|
[57] | |||
Compound Name |
Diethylhexylphthalate
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Investigative | Compound Info | ||
Synonyms |
Di-(2-ethylhexyl) phthalate; CHEMBL402794; ZINC3860432; BDBM50371947; 1-O-[(2S)-2-ethylhexyl] 2-O-[(2R)-2-ethylhexyl] benzene-1,2-dicarboxylate; UNII-C42K0PH13C component BJQHLKABXJIVAM-BGYRXZFFSA-N; 1-O-[(2R)-2-ethylhexyl] 2-O-[(2S)-2-ethylhexyl] benzene-1,2-dicarboxylate
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Activity |
IC50 = 380000 nM
|
[53] | |||
Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-3-[4-(3-methylphenyl)phenyl]-1-oxopropan-2-yl]carbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382001; BDBM50491310
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Activity |
Ki = 389000 nM
|
[16] | |||
Compound Name |
Ethyl (2R,3R)-3-[[(1-acetylpyrrolidine-2-carbonyl)amino]-(2-amino-2-oxoethyl)carbamoyl]oxirane-2-carboxylate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL4111487; BDBM228616; US9345789, LI-1
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Activity |
IC50 = 390000 nM
|
[58] | |||
Compound Name |
(S)-3-((S)-2-Acetylamino-3-carboxy-propionylamino)-N-((1S,2S)-2-methyl-1-{(S)-2-methyl-1-[2-((S)-3,3,4,4,4-pentafluoro-2-oxo-1-propyl-butylcarbamoyl)-pyrrolidine-1-carbonyl]-propylcarbamoyl}-butyl)-succinamic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2370192; BDBM50071973
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Activity |
IC50 = 416000 nM
|
[41] | |||
Compound Name |
7-(Cyanomethylaminomethyl)-5-nitro-8-quinolinol
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2312216; MDK7677; 2-{[(8-Hydroxy-5-nitroquinoline-7- yl)methyl]amino}-acetonitrile; BDBM50425030; 2-[[(8-hydroxy-5-nitroquinolin-7-yl)methyl]amino]acetonitrile
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Activity |
Ki = 426000 nM
|
[24] | |||
Compound Name |
3-(Benzyloxycarbonyl-L-leucylamino)-N-(2-(dimethylamino)-ethyl)-2-oxopentanamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL1242933; BDBM50326305
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Activity |
Ki = 475000 nM
|
[33] | |||
Compound Name |
Chembl4251253
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Investigative | Compound Info | ||
Synonyms |
BDBM50463221
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Activity |
IC50 > 500000 nM
|
[26] | |||
Compound Name |
[(S)-3-Methyl-1-((S)-2-oxo-1-phenethyl-propylcarbamoyl)-butyl]-carbamic acid benzyl ester
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Investigative | Compound Info | ||
Synonyms |
CHEMBL98766; BDBM50119068
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Activity |
Ki = 519000 nM
|
[49] | |||
Compound Name |
N-[(2S)-1-[[(2S)-1,6-Diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]cyclopentene-1-carboxamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382077; BDBM50491283
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Activity |
Ki = 623000 nM
|
[16] | |||
Compound Name |
[4-[[(2S)-1-[[(2S)-1,6-Diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]phenyl] acetate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382070; BDBM50491304
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Activity |
Ki = 706000 nM
|
[16] | |||
Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]carbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382080; BDBM50491300
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Activity |
Ki = 835000 nM
|
[16] | |||
Compound Name |
2-[4-[[(2S)-1-[[(2S)-1,6-Diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyridin-2-yl]pyridine-4-carboxylic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382075; BDBM50491281
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Activity |
Ki = 860000 nM
|
[16] | |||
Compound Name |
[(2S)-3,3-Dimethyl-1-[3-[4-(trifluoromethyl)phenyl]pyrazol-1-yl]butan-2-yl] N-[(3S)-1-(1,2-oxazol-5-ylmethylamino)-1,2-dioxoheptan-3-yl]carbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL365049; BDBM50169489
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Activity |
IC50 = 870000 nM
|
[21] | |||
Compound Name |
[(S)-1-(Thiazol-2-ylaminooxalyl)-pentyl]-carbamic acid (S)-2,2-dimethyl-1-[4-(4-trifluoromethyl-phenyl)-imidazol-1-ylmethyl]-propyl ester
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Investigative | Compound Info | ||
Synonyms |
CHEMBL187864; BDBM50169497
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Activity |
IC50 = 870000 nM
|
[21] | |||
Compound Name |
(S)-3-((S)-2-Acetylamino-3-carboxy-propionylamino)-N-[(1S,2S)-2-methyl-1-((S)-2-methyl-1-{2-[(S)-1-(2,2,2-trifluoro-acetyl)-butylcarbamoyl]-pyrrolidine-1-carbonyl}-propylcarbamoyl)-butyl]-succinamic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL310738; Ac-D-d-I-V-P-Nva-CF3; BDBM50071983; Ac-Aspartic acid-D-Isoleucine-Valine-Norvaline-CF3
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Activity |
IC50 > 900000 nM
|
[41] | |||
Compound Name |
Ethyl (E)-4-[[[(2S)-1-acetylpyrrolidine-2-carbonyl]amino]-(2-amino-2-oxoethyl)amino]-4-oxobut-2-enoate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL1950280; BDBM50364365; BDBM228618; US9345789, LI-2
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Activity |
IC50 > 1000000 nM
|
[58] | |||
Compound Name |
(3S)-3-[[(2S)-1-Acetylpyrrolidine-2-carbonyl]amino]-5-(2,6-dimethylbenzoyl)oxy-4-oxopentanoic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL3954843; BDBM228617; US9345789, LI-0
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Activity |
IC50 > 1000000 nM
|
[58] | |||
Compound Name |
(S)-3-((S)-2-Acetylamino-3-carboxy-propionylamino)-N-((1S,2S)-1-{(S)-1-[2-((S)-1-carboxy-propylcarbamoyl)-pyrrolidine-1-carbonyl]-2-methyl-propylcarbamoyl}-2-methyl-butyl)-succinamic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL306027; Ac-D-D-I-V-P-Nva-OH; BDBM50071975; Acetyl-Aspartic-D-Aspartic-Isoleucine-Valine-Proline-Norvaline-OH
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Activity |
IC50 > 1000000 nM
|
[41] | |||
Compound Name |
[2-[(E)-[2-Methylpropyl-[2-[2-methylpropyl(phenylmethoxycarbonylamino)amino]-2-oxoethyl]hydrazinylidene]methyl]phenyl]boronic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL433563; BDBM50159158
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Activity |
IC50 > 1000000 nM
|
[59] | |||
Compound Name |
(R)-3-((S)-2-Acetylamino-3-carboxy-propionylamino)-N-((1S,2S)-1-{(S)-1-[2-((R)-1-benzylcarbamoyl-butylcarbamoyl)-pyrrolidine-1-carbonyl]-2-methyl-propylcarbamoyl}-2-methyl-butyl)-succinamic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2370189; BDBM50071967
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Activity |
IC50 > 1000000 nM
|
[41] | |||
Compound Name |
[3-[(E)-[Benzyl-[2-[2-methylpropyl(phenylmethoxycarbonylamino)amino]-2-oxoethyl]hydrazinylidene]methyl]phenyl]boronic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL179042; BDBM50159149
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Activity |
IC50 > 1000000 nM
|
[59] | |||
Compound Name |
(R)-2-{[1-((S)-2-{(2S,3S)-2-[(R)-2-((S)-2-Acetylamino-3-carboxy-propionylamino)-3-carboxy-propionylamino]-3-methyl-pentanoylamino}-3-methyl-butyryl)-pyrrolidine-2-carbonyl]-amino}-pentanoic acid benzyl ester
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2370171; BDBM50071970
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Activity |
IC50 > 1000000 nM
|
[41] | |||
Compound Name |
Cbz-Phe-Gly-epoxide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL498580; BDBM50265075
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Activity |
Ki = 1018000 nM
|
[37] | |||
Compound Name |
[3-[[(2S)-1-[[(2S)-1,6-Diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]phenyl] acetate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382069; BDBM50491313
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Activity |
Ki = 1020000 nM
|
[16] | |||
Compound Name |
2-{(R)-3-[(R)-3-((S)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-2-oxo-cyclohexyl]-propionylamino}-3-phenyl-propionic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL76087; BDBM50081423; N-[3-[(1R,3R)-3-[[N-(Benzyloxycarbonyl)phenylalanyl]amino]-2-oxocyclohexyl]propionyl]phenylalanine
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Activity |
Ki = 1100000 nM
|
[60] | |||
Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382081; BDBM50491301
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Activity |
Ki = 1185000 nM
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[16] | |||
Compound Name |
Benzyl N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopentan-2-yl]carbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382082; BDBM50491291
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Activity |
Ki = 1303000 nM
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[16] | |||
Compound Name |
Benzyl N-[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxohexan-2-yl]carbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382083; BDBM50491311
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Activity |
Ki = 1494000 nM
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[16] | |||
Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1-amino-6-(methylamino)-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2381989; BDBM50491282
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Activity |
Ki = 1547000 nM
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[16] | |||
Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1,6-diamino-6-hydroxy-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2381990; BDBM50491309
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Activity |
Ki = 1734000 nM
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[16] | |||
Compound Name |
2-Chloro-N-[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-5-nitrobenzamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382071; BDBM50491319
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Activity |
Ki = 1757000 nM
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[16] | |||
Compound Name |
(2S)-6-Amino-2-[[(2S)-3-phenyl-2-(3-phenylpropanoylamino)propanoyl]amino]hexanamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382078; BDBM50491303
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Activity |
Ki = 2035000 nM
|
[16] | |||
Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1,5-diamino-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2381991; BDBM50491317
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Activity |
Ki = 2460000 nM
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[16] | |||
Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1-amino-3-(4-aminophenyl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2381993; BDBM50491316
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Activity |
Ki = 2787000 nM
|
[16] | |||
Compound Name |
N-[(2S)-1-[[(2S)-1,6-Diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2,6-dimethylbenzamide
Click to Show/Hide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382064; BDBM50491312
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Activity |
Ki = 3387000 nM
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[16] | |||
Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Click to Show/Hide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2381988; BDBM50491308
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Activity |
Ki = 3406000 nM
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[16] | |||
Compound Name |
(1r)-1-{[5-(4-Fluorophenyl)-1,3,4-oxadiazol-2-yl]methyl}-2,2-dimethylpropyl(1S)-1-[oxo(1h-pyrazol-5-ylamino)acetyl]pentylcarbamate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL186149; SCHEMBL6616610; BDBM50169491
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Activity |
IC50 = 3500000 nM
|
[21] | |||
Compound Name |
Benzyl N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]carbamate
Click to Show/Hide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL2382084; BDBM50491325
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Activity |
Ki = 3545000 nM
|
[16] | |||
Compound Name |
Carbobenzyloxy-L-phenylalanyl-L-leucinamide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL423787; Z-Phe-Leu-NH2; Z-L-Phe-L-Leu-NH2; CTK0F5300; DTXSID50539037; ZINC4760773; BDBM50491285; AKOS024432266; N-[(Benzyloxy)carbonyl]-L-phenylalanyl-L-leucinamide; L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-phenylalanyl-
Click to Show/Hide
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Activity |
Ki = 4341000 nM
|
[16] | |||
Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
Synonyms |
CHEMBL2381996; BDBM50491296
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Activity |
Ki = 7096000 nM
|
[16] | |||
Compound Name |
(1R,21S,24S)-21-Tert-butyl-N-[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]-16,16-dimethyl-3,19,22-trioxo-2,18-dioxa-4,20,23-triazatetracyclo[21.2.1.14,7.06,11]heptacosa-6(11),7,9-triene-24-carboxamide
Click to Show/Hide
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Investigative | Compound Info | ||
Synonyms |
CHEMBL599872; SCHEMBL3263999; BDBM50326055
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Activity |
IC50 > 10000000 nM
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[61] | |||
Click to Show/Hide the Information of All Non Binders |
References | Top | ||||
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