Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T69494 | Target Info | |||
| Target Name | N-methyl-D-aspartate receptor (NMDAR) | ||||
| Synonyms |
NMDA-R
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|
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| Target Type | Successful Target | ||||
| Gene Name | NO-GeName | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 63 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
NBQX
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|
Phase 1 | Compound Info | ||
| Synonyms |
nbqx; 118876-58-7; FG 9202; 2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline; 2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline; 6-Nitro-7-sulfamoylbenzo(f)quinoxaline-2,3-dione; CHEMBL222519; CHEBI:31073; SBB066176; 6-nitro-2,3-dioxo-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide; 1,2,3,4-Tetrahydro-6-nitro-2,3-dioxobenzo(f)quinoxaline-8-sulfonamide; 6-Nitro-7-sulphamoylbenzo[f]quinoxaline-2,3-dione; 6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-Dione; 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline
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|
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
arcaine
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|
Investigative | Compound Info | ||
| Synonyms |
arcaine; Tetramethylenediguanide; 1,4-Diguanidinobutane; N,N'''-1,4-Butanediylbisguanidine; Arcain; 544-05-8; 1-(4-guanidinobutyl)guanidine; CHEMBL102740; CHEBI:16652; 1,1'-(butane-1,4-diyl)diguanidine; Guanidine, N,N'''-1,4-butanediylbis-; A-8340; 1-(4-carbamimidamidobutyl)guanidine; 58585-47-0; 2,2'-butane-1,4-diyldiguanidine; Tocris-0389; Spectrum_001819; Prestwick2_000876; Spectrum5_001638; Prestwick1_000876; Prestwick0_000876; Spectrum3_001100; Spectrum2_000601; Prestwick3_000876; Spectrum4_001929; Lopac-A-0384
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| Activity |
IC50 = 79980 nM
|
[2] | |||
| Compound Name |
2-[(E)-1H-Indol-5-ylmethylideneamino]guanidine;hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346816; SCHEMBL5703222; BDBM50490853
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|
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| Activity |
IC50 = 50118.72 nM
|
[3] | |||
| Compound Name |
(1S,Alphar)-1,2,3,4-Tetrahydro-2-methyl-6,7-dimethoxy-alpha-(4-chlorophenyl)-1-isoquinolineethanol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL195973
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|
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| Activity |
IC50 = 52000 nM
|
[4] | |||
| Compound Name |
5-Acetoxy-1,4-dihydro-6,7-dimethoxyquinoxaline-2,3-dione
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL295427; SCHEMBL7779824; SCHEMBL8127933; (6,7-dimethoxy-2,3-dioxo-1,4-dihydroquinoxalin-5-yl) Acetate; BDBM50056603; Acetic acid 6,7-dimethoxy-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin-5-yl ester
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|
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| Activity |
IC50 = 53000 nM
|
[5] | |||
| Compound Name |
Amino(2-(2,4-Difluorobenzylidene)Hydrazinyl)Methaniminium Chloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346940; SCHEMBL5702915; BDBM50490858
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|
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| Activity |
IC50 = 54954.09 nM
|
[3] | |||
| Compound Name |
1-[[3-[[Carbamimidoyl(propyl)amino]methyl]-5-methoxyphenyl]methyl]-1-propylguanidine;dihydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL116027
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|
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| Activity |
IC50 = 55260 nM
|
[2] | |||
| Compound Name |
(1R,Alphar)-1,2,3,4-Tetrahydro-2-methyl-6,7-dimethoxy-alpha-(4-chlorophenyl)-1-isoquinolineethanol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL194598
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|
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| Activity |
IC50 = 56000 nM
|
[4] | |||
| Compound Name |
2-[(E)-1H-Indol-2-ylmethylideneamino]guanidine;hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346817; BDBM50490854
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|
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| Activity |
IC50 = 57543.99 nM
|
[3] | |||
| Compound Name |
Amino(2-(3-Phenylallylidene)Hydrazinyl)Methaniminium Chloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346812; BDBM50490870
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|
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| Activity |
IC50 = 58884.37 nM
|
[3] | |||
| Compound Name |
3-[3-(Ethylamino)propanoylamino]propanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3219496; AKOS012130256
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|
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| Activity |
IC50 = 60000 nM
|
[6] | |||
| Compound Name |
2-(4-Aminobutanamido)acetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL557092; N-(4-Amino-butyryl)-glycine; Aminobutyrylglycin; SCHEMBL540700; 2-(4-aminobutanoylamino)acetic acid; BDBM50294730
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|
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| Activity |
IC50 = 61000 nM
|
[6] | |||
| Compound Name |
3-Nitro-4-hydroxy-5-chloroquinolin-2(1H)-one
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL288904
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|
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| Activity |
IC50 = 61000 nM
|
[5] | |||
| Compound Name |
2-[(E)-(3-Hydroxy-4-methoxyphenyl)methylideneamino]guanidine;hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346947; BDBM50490860
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|
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| Activity |
IC50 = 63095.73 nM
|
[3] | |||
| Compound Name |
Amino(2-(4-(Methoxycarbonyl)Benzylidene)Hydrazinyl)Methaniminium Chloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346959; BDBM50490880
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|
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| Activity |
IC50 = 70794.58 nM
|
[3] | |||
| Compound Name |
Amino(2-Benzylidenehydrazinyl)Methaniminium Chloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL296174; SCHEMBL9618642; BDBM50490879
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|
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| Activity |
IC50 = 72443.6 nM
|
[3] | |||
| Compound Name |
Amino(2-(3-(Methoxycarbonyl)Benzylidene)Hydrazinyl)Methaniminium Chloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346958; BDBM50490878
Click to Show/Hide
|
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| Activity |
IC50 = 72443.6 nM
|
[3] | |||
| Compound Name |
Amino(2-(2-Fluorobenzylidene)Hydrazinyl)Methaniminium Chloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346942; SCHEMBL17560818; BDBM50191304
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|
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| Activity |
IC50 = 74131.02 nM
|
[3] | |||
| Compound Name |
1-[[3-[[Carbamimidoyl(ethyl)amino]methyl]phenyl]methyl]-1-ethylguanidine;dihydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL115747
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|
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| Activity |
IC50 = 75800 nM
|
[2] | |||
| Compound Name |
Amino(2-(4-Nitrobenzylidene)Hydrazinyl)Methaniminium Chloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL104315; BDBM50191283
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|
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| Activity |
IC50 = 77624.71 nM
|
[3] | |||
| Compound Name |
Amino(2-(4-Methylbenzylidene)Hydrazinyl)Methaniminium Chloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL320890; SCHEMBL17560739; BDBM50490872
Click to Show/Hide
|
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| Activity |
IC50 = 81283.05 nM
|
[3] | |||
| Compound Name |
Amino(2-(4-Fluorobenzylidene)Hydrazinyl)Methaniminium Chloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346941; SCHEMBL6510878; BDBM50191299
Click to Show/Hide
|
||||
| Activity |
IC50 = 91201.08 nM
|
[3] | |||
| Compound Name |
(1S,Alphar)-1,2,3,4-Tetrahydro-6,7-dimethoxy-alpha-(4-chlorophenyl)-1-isoquinolineethanol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL193980
Click to Show/Hide
|
||||
| Activity |
IC50 = 95000 nM
|
[4] | |||
| Compound Name |
1-[[6-[[Carbamimidoyl(propyl)amino]methyl]pyridin-2-yl]methyl]-1-propylguanidine;dihydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL116333
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|
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| Activity |
IC50 = 95210 nM
|
[2] | |||
| Compound Name |
2-[(E)-1H-Pyrrol-2-ylmethylideneamino]guanidine;hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346933; NSC67609; BDBM50490856; NSC-67609
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|
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| Activity |
IC50 = 95499.26 nM
|
[3] | |||
| Compound Name |
2-Amino-3-[3-hydroxy-5-(1-methyl-1H-tetrazol-5-yl)-isoxazol-4-yl]-propionic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL317790; SCHEMBL13319946; BDBM50059674; (RS)-2-amino-3-[3-hydroxy-5-(1-methyl-2H-5-tetrazolyl)-4-isoxazolyl]propionic acid
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|
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| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
1,3-Bis(4-amino-2-methylphenyl)guanidine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL79165; BDBM50010770; ZINC26480112; N,N''-Bis-(4-amino-2-methyl-phenyl)-guanidine (3HCl)
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|
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| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
6-Chloro-4-hydroxy-3-phenyl-1H-1,8-naphthyridin-2-one
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40555; SCHEMBL8692310; ZINC29345520
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
(2R)-2-Amino-3-(2H-tetrazol-5-yl)propanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL145728; SCHEMBL7354483; ZINC5502361
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
(2S)-2-Amino-3-(2H-tetrazol-5-yl)propanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
NSC-173723; NCIStruc1_000244; NCIStruc2_000262; CHEMBL357426; SCHEMBL1891365; ZINC5502359; CCG-38039; NCGC00014505; NCI173723; NCGC00014505-02; NCGC00097609-01; (2~{S})-2-azanyl-3-(1~{H}-1,2,3,4-tetrazol-5-yl)propanoic acid
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
2-Amino-3-[5-(2-methyl-1,2,4-triazol-3-yl)-3-oxo-1,2-oxazol-4-yl]propanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL328310
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
n,n-Diphenylguanidine
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|
Investigative | Compound Info | ||
| Synonyms |
1,1-diphenylguanidine; Guanidine, N,N-diphenyl-; UNII-CL047JBJ5Q; N,N-Diphenyl-guanidine; CL047JBJ5Q; CHEMBL79616; diphenylguanidin; Guanidine, diphenyl-; 1,1-Di(phenyl)guanidine; ACMC-1CIJ0; SCHEMBL36862; CTK1A5527; DTXSID70174126; ADAL1043435; ZINC4018857; BDBM50010737; Q27275513
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
2-Amino-8-(2H-tetrazol-5-yl)octanoic acid;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL544391
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
5,8-Dihydro-[1,3]dioxolo[4,5-g]quinoxaline-6,7-dione
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43875; 1,3-Dioxolo[4,5-g]quinoxaline-6,7-dione, 5,8-dihydro-; SCHEMBL7786492; SCHEMBL8129028; BDBM50056609; 6,7-Methylenedioxy-1,4-dihydroquinoxaline-2,3-dione; 5,8-Dihydro-1,3-dioxa-5,8-diaza-cyclopenta[b]naphthalene-6,7-dione
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
4-Hydroxy-3-phenyl-1,5-naphthyridin-2(1H)-one
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40193; SCHEMBL8695592; DTXSID50716361; ZINC29347641; DB-082876; FT-0710665; 4-hydroxy-3-phenyl-1H-1,5-naphthyridin-2-one
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
3-Nitro-4-hydroxy-5,6,7,8-tetrafluoroquinolin-2(1H)-one
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL41538; SCHEMBL8896130; 5,6,7,8-Tetrafluoro-4-hydroxy-3-nitro-1H-quinolin-2-one
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
4-Hydroxy-3-phenyl-1,8-naphthyridin-2(1H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
NSC318518; CHEMBL289756; SCHEMBL8692300; CTK5C6801; DTXSID70716005; ZINC1571950; NSC-318518; DB-082664; FT-0710840; 4-hydroxy-3-phenyl-1H-1,8-naphthyridin-2-one; 1,8-Naphthyridin-2(1H)-one,4-hydroxy-3-phenyl-
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
2-[3-(Diethylamino)propyl]-2-methyl-4-phenylfuran-3-one;hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL543587
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|
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| Activity |
Ki = 100000 nM
|
[10] | |||
| Compound Name |
2-Amino-7-(2H-tetrazol-5-yl)heptanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL357463
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5-yl)-isoxazol-4-yl]-propionic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL94859; (S)-2-AMINO-3-[3-HYDROXY-5-(2-METHYL-2H-TETRAZOL-5-YL)ISOXAZOL-4-YL]PROPIONIC ACID; SCHEMBL13319955; BDBM50059672; Q27458470; 2-amino-3-[3-hydroxy-5-(2-methyl-2h-tetrazol-5-yl)isoxazol-4-yl]propionic acid
Click to Show/Hide
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| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
2-Amino-3-[3-oxo-5-(2H-tetrazol-5-yl)-1,2-oxazol-4-yl]propanoic Acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL94860; SCHEMBL7412093
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
2-Amino-3-[3-oxo-5-(1H-1,2,4-triazol-5-yl)-1,2-oxazol-4-yl]propanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL318467
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
2-Amino-3-[5-(1-methyl-1,2,4-triazol-3-yl)-3-oxo-1,2-oxazol-4-yl]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL441460
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
2-Amino-3-[5-(1H-imidazol-2-yl)-3-oxo-1,2-oxazol-4-yl]propanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97742
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
2-Amino-3-[3-oxo-5-(1,3-thiazol-2-yl)-1,2-oxazol-4-yl]propanoic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL310897; SCHEMBL8132958
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
3-Nitro-4-hydroxy-6,7,8-trichloroquinolin-2(1H)-one
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44079; SCHEMBL8897024; 6,7,8-Trichloro-4-hydroxy-3-nitro-1H-quinolin-2-one
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
2-Amino-3-[5-(1-methylimidazol-2-yl)-3-oxo-1,2-oxazol-4-yl]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL98723
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
2(1H)-Quinolinone, 6-chloro-4-hydroxy-3-nitro-
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL404811; CHEMBL295179; ZINC2243886; 6-chloro-4-hydroxy-3-nitrocarbostyril; DA-16726; FT-0753278; 3-Nitro-4-hydroxy-6-chloroquinolin-2(1H)-one; 6-Chloro-4-hydroxy-3-nitro-1H-quinolin-2-one; 6-Chloro-4-hydroxy-3-nitroquinolin-2(1H)-one
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
8-Chloroquinoline-2,3,4(1H)-trione 3-oxime
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43918; BDBM50052632; 8-Chloro-1H-quinoline-2,3,4-trione 3-oxime
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
8-Chloro-4-hydroxy-3-nitroquinolin-2(1H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL296558; SCHEMBL8896132; 3-Nitro-4-hydroxy-8-chloroquinolin-2(1H)-one; 8-Chloro-4-hydroxy-3-nitro-1H-quinolin-2-one
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
2,3-Quinoxalinedione, 1,4-dihydro-6,7-dihydroxy-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43910; 6,7-dihydroxy-1,4-dihydroquinoxaline-2,3-dione; SCHEMBL7784305; SCHEMBL8120664; SCHEMBL16547258; BDBM50056608; 6,7-Dihydroxy-1,4-dihydro-quinoxaline-2,3-dione
Click to Show/Hide
|
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
2-[(E)-[5-(4-Nitrophenyl)furan-2-yl]methylideneamino]guanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346934; BDBM50490857
Click to Show/Hide
|
||||
| Activity |
IC50 = 109647.82 nM
|
[3] | |||
| Compound Name |
Amino(2-(4-Aminobenzylidene)Hydrazinyl)Methaniminium Chloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346948; BDBM50490862
Click to Show/Hide
|
||||
| Activity |
IC50 = 109647.82 nM
|
[3] | |||
| Compound Name |
(1S,Alphar)-1,2,3,4-Tetrahydro-6,7-dimethoxy-alpha-(4-methoxyphenyl)-1-isoquinolineethanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL196080
Click to Show/Hide
|
||||
| Activity |
IC50 = 110000 nM
|
[4] | |||
| Compound Name |
1-[[3-[[Carbamimidoyl(propyl)amino]methyl]-5-hydroxyphenyl]methyl]-1-propylguanidine;dihydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL436361
Click to Show/Hide
|
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| Activity |
IC50 = 110500 nM
|
[2] | |||
| Compound Name |
(2R)-2-(2-Aminoethylamino)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3219495; SCHEMBL15453401; AKOS021520413
Click to Show/Hide
|
||||
| Activity |
IC50 = 112000 nM
|
[6] | |||
| Compound Name |
1-[[3-[[Carbamimidoyl(2-methylpropyl)amino]methyl]phenyl]methyl]-1-(2-methylpropyl)guanidine;dihydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL117468
Click to Show/Hide
|
||||
| Activity |
IC50 = 112030 nM
|
[2] | |||
| Compound Name |
(1R,Alphar)-1,2,3,4-Tetrahydro-6,7-dimethoxy-alpha-(4-methoxyphenyl)-1-isoquinolineethanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL371669
Click to Show/Hide
|
||||
| Activity |
IC50 = 120000 nM
|
[4] | |||
| Compound Name |
(1R,Alphas)-1,2,3,4-Tetrahydro-2-methyl-6,7-dimethoxy-alpha-(4-methoxyphenyl)-1-isoquinolineethanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL196828
Click to Show/Hide
|
||||
| Activity |
IC50 = 120000 nM
|
[4] | |||
| Compound Name |
(1R,Alphas)-1,2,3,4-Tetrahydro-6,7-dimethoxy-alpha-(4-methoxyphenyl)-1-isoquinolineethanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL197106
Click to Show/Hide
|
||||
| Activity |
IC50 = 140000 nM
|
[4] | |||
| Compound Name |
Amino(2-(3-Nitrobenzylidene)Hydrazinyl)Methaniminium Chloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL106177; BDBM50490861
Click to Show/Hide
|
||||
| Activity |
IC50 = 154881.66 nM
|
[3] | |||
| Compound Name |
2-[(E)-Thiophen-3-ylmethylideneamino]guanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346813; BDBM50490882
Click to Show/Hide
|
||||
| Activity |
IC50 = 181970.09 nM
|
[3] | |||
| Compound Name |
Click to Show/Hide
|
Compound Info | |||
| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 81 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Licostinel
Click to Show/Hide
|
Discontinued in Phase 1 | Compound Info | ||
| Synonyms |
Licostinel; 153504-81-5; ACEA 1021; ACEA-1021; UNII-3Z3037LJTC; 6,7-Dichloro-5-nitro-2,3-quinoxalinedione; 5-Nitro-6,7-dichloro-2,3-quinoxalinedione; 5-Nitro-6,7-dichloro-1,4-dihydro-2,3-quinoxalinedione; 6,7-Dichloro-1,4-dihydro-5-nitro-2,3-quinoxalinedione; CHEMBL289832; 3Z3037LJTC; 6,7-dichloro-5-nitro-1,4-dihydroquinoxaline-2,3-dione; 6,7-DICHLORO-5-NITROQUINOXALINE-2,3(1H,4H)-DIONE; 2,3-Quinoxalinedione, 6,7-dichloro-1,4-dihydro-5-nitro-; Licostinel [USAN]; Licostinel [USAN:INN]; C8H3Cl2N3O4; AC1NUOFE; Licostinel (USAN/
Click to Show/Hide
|
||||
| Activity |
IC50 = 5888436.55 nM
|
[5] | |||
| Compound Name |
5,6,7-Trichloro-1,4-dihydro-quinoxaline-2,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5,6,7-trichloro-1,4-dihydroquinoxaline-2,3-dione; CHEMBL43846; 172215-97-3; 5,6,7-Trichloro-1,4-dihydro-quinoxaline-2,3-dione; SCHEMBL8904175
Click to Show/Hide
|
||||
| Activity |
IC50 = 29512092.27 nM
|
[5] | |||
| Compound Name |
6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
25983-13-5; 6,7-Dichloroquinoxaline-2,3(1H,4H)-dione; DCQX; 6,7-dichloroquinoxaline-2,3-diol; 6,7-DICHLORO-1,4-DIHYDRO-2,3-QUINOXALINEDIONE; 6,7-dichloro-1,4-dihydroquinoxaline-2,3-dione; 2,3-Dihydroxy-6,7-dichloroquinoxaline; 6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione; CHEMBL284028; Spectrum_001661; ACMC-209gnv; SpecPlus_000650; Lopac-D-133; AC1L1CDC; Spectrum5_001426; Spectrum4_000630; Spectrum3_001668; Spectrum2_000537; Biomol-NT_000181; AC1Q3Q7M; Lopac0_000418; KBioSS_002141; KBioGR_001220; BSPBio_003455; Benzil-related co
Click to Show/Hide
|
||||
| Activity |
IC50 = 128824955.2 nM
|
[5] | |||
| Compound Name |
5,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL282003; 5,7-dichloroquinoxaline-2,3-diol; 5,7-Dichloro-quinoxaline-2,3-diol; BAS 01357242; 5,7-dichloro-1,4-dihydroquinoxaline-2,3-dione; 5,7-Dichloro-1,4-dihydro-2,3-quinoxalinedione; MLS000026787; AC1LCHFV; 5,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione; Oprea1_426848; SCHEMBL7345532; SCHEMBL2639494; MolPort-002-737-915; DBSHFABBWSZJLZ-UHFFFAOYSA-N; HMS2397P18; ZINC12428297; STK782684; BDBM50008757; AKOS022421131; AKOS005619834; AKOS000543707; MCULE-5094494417; ST088493; ST042190; SMR000010423; 4029-54-3
Click to Show/Hide
|
||||
| Activity |
IC50 = 281838293.1 nM
|
[5] | |||
| Compound Name |
6-Chloro-1,4-dihydro-quinoxaline-2,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
6-chloroquinoxaline-2,3-diol; 6639-79-8; 2,3-Dihydroxy-6-chloroquinoxaline; 6-Chloro-1,4-dihydroquinoxaline-2,3-dione; 6-Chloroquinoxaline-2,3(1H,4H)-dione; 6-Chloro-2,3-dihydroxyquinoxaline; 6-Chloro-1,2,3,4-tetrahydroquinoxaline-2,3-dione; 169-14-2; 2,3-Quinoxalinedione, 6-chloro-1,4-dihydro-; CHEMBL21641; 6-CHLORO-2,3-DIOXO-1,2,3,4-TETRAHYDROQUINOXALINE; 6-chloro-1,4-dihydro-2,3-quinoxalinedione; Oprea1_205811; 2,3-Quinoxalinediol, 6-chloro-; EINECS 229-647-9; NSC 48940; PubChem15426; 2, 6-chloro-; AC1Q3ORE
Click to Show/Hide
|
||||
| Activity |
IC50 = 562341325.2 nM
|
[5] | |||
| Compound Name |
Amino(2-(2,4-Dihydroxybenzylidene)Hydrazinyl)Methaniminium Chloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346951; BDBM50490863
Click to Show/Hide
|
||||
| Activity |
IC50 = 213796.21 nM
|
[3] | |||
| Compound Name |
Amino(2-(3-Aminobenzylidene)Hydrazinyl)Methaniminium Chloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346949; BDBM50490877
Click to Show/Hide
|
||||
| Activity |
IC50 = 223872.11 nM
|
[3] | |||
| Compound Name |
Amino(2-(4-Cyanobenzylidene)Hydrazinyl)Methaniminium Chloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346957; BDBM50490865
Click to Show/Hide
|
||||
| Activity |
IC50 = 229086.77 nM
|
[3] | |||
| Compound Name |
(1R,Alphar)-1,2,3,4-Tetrahydro-6,7-dimethoxy-alpha-(4-chlorophenyl)-1-isoquinolineethanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL196402
Click to Show/Hide
|
||||
| Activity |
IC50 = 290000 nM
|
[4] | |||
| Compound Name |
(S)-3-(Aminomethyl)piperazine-2,5-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1237203; BDBM50414372; ZINC43120518; AKOS006348808; F2147-3002
Click to Show/Hide
|
||||
| Activity |
IC50 = 370000 nM
|
[6] | |||
| Compound Name |
2-[(E)-Pyridin-4-ylmethylideneamino]guanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346931; BDBM50490855
Click to Show/Hide
|
||||
| Activity |
IC50 = 537031.8 nM
|
[3] | |||
| Compound Name |
2-[(E)-Pyridin-3-ylmethylideneamino]guanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346932; NSC18374; BDBM50490874; NSC-18374
Click to Show/Hide
|
||||
| Activity |
IC50 = 676082.98 nM
|
[3] | |||
| Compound Name |
7-Chloro-6-methyl-5-nitro-1,4-dihydro-quinoxaline-2,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL297881; ACEA-1416; 7-chloro-6-methyl-5-nitro-1,4-dihydroquinoxaline-2,3-dione; SCHEMBL7467072; SCHEMBL8113141; BDBM50056605; 7-Chloro-1,4-dihydro-6-methyl-5-nitroquinoxaline-2,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 4677351.41 nM
|
[5] | |||
| Compound Name |
5,6,7-Trichloro-3-hydroxyimino-1H-quinoline-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL288855; SCHEMBL7050694; BDBM50052635; 5,6,7-Trichloro-1H-quinoline-2,3,4-trione 3-oxime; 5,6,7-Trichloroquinoline-2,3,4(1H)-trione 3-oxime
Click to Show/Hide
|
||||
| Activity |
IC50 = 7079457.84 nM
|
[5] | |||
| Compound Name |
7-Bromo-6-methyl-5-nitro-1,4-dihydroquinoxaline-2,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42426; SCHEMBL7779841; SCHEMBL8127659; BDBM50056596; 7-Bromo-6-methyl-5-nitro-1,4-dihydro-quinoxaline-2,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 8709635.9 nM
|
[5] | |||
| Compound Name |
6,7-Dichloro-3-hydroxyimino-1H-quinoline-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40623; SCHEMBL7052285; BDBM50052629; 6,7-Dichloro-1H-quinoline-2,3,4-trione 3-oxime; 6,7-Dichloroquinoline-2,3,4(1H)-trione 3-oxime
Click to Show/Hide
|
||||
| Activity |
IC50 = 12022644.35 nM
|
[5] | |||
| Compound Name |
7-Chloro-4-hydroxy-3-(3-phenylphenoxy)-1H-1,5-naphthyridin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40976
Click to Show/Hide
|
||||
| Activity |
IC50 = 22908676.53 nM
|
[5] | |||
| Compound Name |
3-Nitro-4-hydroxy-6,8-difluoro-7-chloroquinolin-2(1H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL298232
Click to Show/Hide
|
||||
| Activity |
IC50 = 25118864.32 nM
|
[5] | |||
| Compound Name |
6,7-Dimethyl-5-nitro-1,4-dihydroquinoxaline-2,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
ACEA-1328; CHEMBL41460; SCHEMBL7471983; SCHEMBL8113307; ZINC6308; 2,3-Quinoxalinedione, 1,4-dihydro-6,7-dimethyl-5-nitro-; BDBM50056595; 1,4-dihydro-6,7-dimethyl-5-nitroquinoxalin-2,3-dione; 6,7-Dimethyl-5-nitro-1,4-dihydro-quinoxaline-2,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 28840315.03 nM
|
[5] | |||
| Compound Name |
6-Chloro-7-ethyl-5-nitro-1,4-dihydroquinoxaline-2,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40652; SCHEMBL7473960; SCHEMBL8128533; 2,3-Quinoxalinedione, 6-chloro-7-ethyl-1,4-dihydro-5-nitro-; BDBM50056620; 5-Nitro-6-chloro-7-ethylquinoxaline-2,3(1H,4H)-dione; 1,4-dihydro-6-chloro-7-ethyl-5-nitroquinoxalin-2,3-dione; 6-Chloro-7-ethyl-5-nitro-1,4-dihydro-quinoxaline-2,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 28840315.03 nM
|
[5] | |||
| Compound Name |
3-Nitroquinoline-2,4-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2,4-Dihydroxy-3-nitroquinoline; 2(1H)-Quinolinone,4-hydroxy-3-nitro-; 4-hydroxy-3-nitro-1,2-dihydroquinolin-2-one; 4-Hydroxy-3-nitro-1H-quinolin-2-one; 3-NITRO-2,4-QUINOLINEDIOL; 2-hydroxy-3-nitro-1H-quinolin-4-one; 4-hydroxy-3-nitro-2(1H)-quinolinone; Oprea1_323032; 4-Hydroxy-3-nitrocarbostyril; SCHEMBL251627; CHEMBL296577; QUI087; 4-hydroxy-3-nitro-2-quinolone; SCHEMBL13295319; CTK4C7090; DTXSID70715674; CS-B0977; ZINC8737708; MFCD01100327; STK735624; AKOS001736021; AKOS026727289; 3-Nitro-4-hydroxyquinolin-2(1H)-one; 4-Hydroxy-3-nitroquinolin-2(1H)-one; AB08266; CCG-251233; MCULE-7224861585; NE44968; 4-hydroxy-3-nitro-2(I H)-quinolinone; 2(1H)-Quinolinone, 4-hydroxy-3-nitro-; AS-62773; SC-53076; ST057496; 3-Nitro4-hydroxy-1,2-dihydroquinolin-2-one; 2-hydroxy-3-nitro-1,4-dihydroquinolin-4-one; 3-Nitro-4-hydroxy-1,2-dihydroquinolin-2-one; BRD-K19179266-001-01-3; Z1575143776
Click to Show/Hide
|
||||
| Activity |
IC50 = 29512092.27 nM
|
[5] | |||
| Compound Name |
4-Hydroxy-3-(3-phenoxyphenyl)-1H-1,8-naphthyridin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL290321
Click to Show/Hide
|
||||
| Activity |
IC50 = 32359365.69 nM
|
[5] | |||
| Compound Name |
5,7-Dichloro-3-oximinoquinoline-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42915; SCHEMBL7052297; SCHEMBL8874088; BDBM50052625; 5,7-Dichloro-1H-quinoline-2,3,4-trione 3-oxime; 5,7-Dichloroquinoline-2,3,4(1H)-trione 3-oxime; 5,7-dichloro-3-hydroxyimino-1H-quinoline-2,4-dione; 5,7-Dichloro-1,2,3,4-tetrahydroquinoline-2,3,4-trione-3-oxime
Click to Show/Hide
|
||||
| Activity |
IC50 = 33113112.15 nM
|
[5] | |||
| Compound Name |
7-Chloro-4-hydroxy-3-nitro-1H-1,8-naphthyridin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL295178
Click to Show/Hide
|
||||
| Activity |
IC50 = 34673685.05 nM
|
[5] | |||
| Compound Name |
2,3,4(1H)-Quinolinetrione, 5,7-dimethyl-, 3-oxime
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42146; SCHEMBL8873148; BDBM50052626; 5,7-dimethylquinoline-2,3,4-trione-3-oxime; 5,7-Dimethyl-1H-quinoline-2,3,4-trione 3-oxime; 5,7-Dimethylquinoline-2,3,4(1H)-trione 3-oxime; 3-hydroxyimino-5,7-dimethyl-1H-quinoline-2,4-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 37153522.91 nM
|
[5] | |||
| Compound Name |
7-Chloro-3-(2-chlorophenyl)-4-hydroxy-1H-1,5-naphthyridin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43800
Click to Show/Hide
|
||||
| Activity |
IC50 = 41686938.35 nM
|
[5] | |||
| Compound Name |
6-Chloro-7-methyl-5-nitro-1,4-dihydroquinoxaline-2,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL41691; SCHEMBL7345843; SCHEMBL8121622; BDBM50056600; 6-Chloro-7-methyl-5-nitro-1,4-dihydro-quinoxaline-2,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 44668359.22 nM
|
[5] | |||
| Compound Name |
4-Hydroxy-3-(3-phenoxyphenyl)-1H-1,6-naphthyridin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40755; ZINC29344705
Click to Show/Hide
|
||||
| Activity |
IC50 = 50118723.36 nM
|
[5] | |||
| Compound Name |
7-Chloro-3-hydroxyimino-1H-quinoline-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL295154; SCHEMBL7049823; BDBM50052631; 7-Chloro-1H-quinoline-2,3,4-trione 3-oxime; 7-Chloroquinoline-2,3,4(1H)-trione 3-oxime
Click to Show/Hide
|
||||
| Activity |
IC50 = 52480746.02 nM
|
[5] | |||
| Compound Name |
6-Chloro-4-hydroxy-3-(3-phenoxyphenyl)-1H-1,8-naphthyridin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL41939
Click to Show/Hide
|
||||
| Activity |
IC50 = 52480746.02 nM
|
[5] | |||
| Compound Name |
2,3-Quinoxalinedione, 1,4-dihydro-5-hydroxy-6,7-dimethoxy-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42367; SCHEMBL7784652; BDBM50056604; 5-Hydroxy-6,7-dimethoxyquinoxaline-2,3(1H,4H)-dione; 5-hydroxy-6,7-dimethoxy-1,4-dihydroquinoxaline-2,3-dione; 5-Hydroxy-6,7-dimethoxy-1,4-dihydro-quinoxaline-2,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 58884365.54 nM
|
[5] | |||
| Compound Name |
2,3-Dihydroxy-6,7-dimethoxyquinoxaline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
6,7-Dimethoxyquinoxaline-2,3(1H,4H)-dione; 6,7-dimethoxy-1,4-dihydroquinoxaline-2,3-dione; CHEMBL42430; 6,7-Dimethoxy-1,4-dihydro-2,3-quinoxalinedione; MFCD09953682; ACMC-20aogl; SCHEMBL1258372; SCHEMBL8114811; CTK4J0374; KS-00000MLC; DTXSID10346648; BDBM50056599; MFCD04038944; ZINC15020540; DS-9831; AK187853; CS-0084773; FT-0609663; 2,3-Quinoxalinedione,1,4-dihydro-6,7-dimethoxy-; 6,7-Dimethoxy-1,4-dihydro-quinoxaline-2,3-dione; 6,7-Dimethoxy-1,4-dihydro-2,3-quinoxalinedione monohydrate, 98%
Click to Show/Hide
|
||||
| Activity |
IC50 = 58884365.54 nM
|
[5] | |||
| Compound Name |
1,4-Dihydrobenzo[g]quinoxaline-2,3-dione
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL43869; benzo[g]quinoxaline-2,3(1H,4H)-dione; Benzo[g]quinoxaline-2,3-dione, 1,4-dihydro-; SCHEMBL2428383; SCHEMBL8121209; SCHEMBL18397673; CTK0E2210; DTXSID40445375; BDBM50056607; 1,4-Dihydrobenzo[g]quinoxalin-2,3-dione; 1,4-Dihydro-benzo[g]quinoxaline-2,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 63095734.45 nM
|
[5] | |||
| Compound Name |
5-Nitro-6-methoxy-7-bromoquinoxaline-2,3(1H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42248; BDBM50056591; 7-Bromo-6-methoxy-5-nitro-1,4-dihydro-quinoxaline-2,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 64565422.9 nM
|
[5] | |||
| Compound Name |
1H-Cyclopenta[g]quinoxaline-2,3-dione, 4,6,7,8-tetrahydro-
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL442545; BDBM50056619; 4,6,7,8-Tetrahydro-1H-cyclopenta[g]quinoxaline-2,3-dione
Click to Show/Hide
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||||
| Activity |
IC50 = 67608297.54 nM
|
[5] | |||
| Compound Name |
7-Methyl-8-nitro-2,3-dioxo-1,4-dihydroquinoxaline-6-carbonitrile
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL288839; SCHEMBL3674477; SCHEMBL3682032; BDBM50056598; 7-Methyl-8-nitro-2,3-dioxo-1,2,3,4-tetrahydro-quinoxaline-6-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 = 72443596.01 nM
|
[5] | |||
| Compound Name |
7-Chloro-3-(4-chlorophenyl)-4-hydroxy-1H-1,5-naphthyridin-2-one
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL417710
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| Activity |
IC50 = 77624711.66 nM
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[5] | |||
| Compound Name |
5-Nitro-6-bromo-7-ethylquinoxaline-2,3(1H,4H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL291149; SCHEMBL7351960; 6-bromo-7-ethyl-5-nitro-1,4-dihydroquinoxaline-2,3-dione; BDBM50056611; 6-Bromo-7-ethyl-5-nitro-1,4-dihydro-quinoxaline-2,3-dione
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| Activity |
IC50 = 81283051.62 nM
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[5] | |||
| Compound Name |
6-Amino-7-fluoro-5-nitro-1,4-dihydroquinoxaline-2,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL43848; SCHEMBL7786771; BDBM50056612; 5-Nitro-6-amino-7-fluoroquinoxaline-2,3(1H,4H)-dione; 6-Amino-7-fluoro-5-nitro-1,4-dihydro-quinoxaline-2,3-dione
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| Activity |
IC50 = 91201083.94 nM
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[5] | |||
| Compound Name |
7-Fluoro-6-methyl-5-nitro-1,4-dihydroquinoxaline-2,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL291148; SCHEMBL3670047; SCHEMBL3681469; BDBM50056597; 7-Fluoro-6-methyl-5-nitro-1,4-dihydro-quinoxaline-2,3-dione
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| Activity |
IC50 = 95499258.6 nM
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[5] | |||
| Compound Name |
2,3-Dihydroxyquinoxaline
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Investigative | Compound Info | ||
| Synonyms |
Quinoxaline-2,3-diol; Quinoxaline-2,3(1H,4H)-dione; 2,3-QUINOXALINEDIOL; 1,4-Dihydro-2,3-quinoxalinedione; 2,3-Quinoxalinedione, 1,4-dihydro-; 1,4-dihydroquinoxaline-2,3-dione; USAF EK-6232; 2,3(1H,4H)-Quinoxalinedione; Quinoxaline, 2,3-dihydroxy-; NSC 8698; 1,4-Dihydro-quinoxaline-2,3-dione; EINECS 239-901-0; MFCD00006723; UNII-APO55IZ9E1; APO55IZ9E1; AI3-03736; CHEMBL282672; 1,3-quinoxalinedione; 1,2,3,4-tetrahydroquinoxaline-2,3-dione; Quinoxaline,3-dihydroxy-; WLN: T66 BN ENJ CQ DQ; hydroxyquinoxalone; ACMC-209xgn; 2,3-Dihydroxyphenpiazine; ACMC-1B2H3; KSC497G8N; MLS000681641; SCHEMBL239920; ARONIS014393; DTXSID9065946; 2,3-Dihydroxyquinoxaline, 98%; CTK3J7386; KS-00000MLG; NSC8698; NSC9431; Quinoxalin-2,3(1H,4H)-Dione; 2,3(1H, 4H)-Quinoxalinedione; HMS2750H11; KUC106696N; NSC-8698; NSC-9431; 1,4-Dihydro quinoxaline-2,3-dione; 8041AF; ANW-21746; ANW-47637; BBL004435; BBL009202; BDBM50008752; CCG-49235; SBB000138; STK264174; STL125448; ZINC18182210; AKOS000503008; AKOS001280678; AB06251; MCULE-6753530638; NE10454; CIS-11-EICOSENOICACIDMETHYLESTER; KS-000044U8; NCGC00245941-01; 2(1H), 3(4H)-QUINOXALINEDIONE; AK-45516; BR-45516; KSC-11-207-7; SMR000312325; ST003022; DB-043375; LS-143031; AM20070315; BB 0242095; BB 0258963; D1010; EU-0000335; FT-0609673; FT-0609674; FT-0691401; W3434; K-4961; 10.14272/ABJFBJGGLJVMAQ-UHFFFAOYSA-N.2; 804D190; AA-516/30054034; SR-01000391115; doi:10.14272/ABJFBJGGLJVMAQ-UHFFFAOYSA-N.2; SR-01000391115-1; SR-01000391115-2; W-107998; F0266-0994
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| Activity |
IC50 = 102329299.2 nM
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[5] | |||
| Compound Name |
7-Chloro-4-hydroxy-3-thiophen-2-yl-1H-1,5-naphthyridin-2-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL41791
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| Activity |
IC50 = 102329299.2 nM
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[5] | |||
| Compound Name |
7-Methyl-5-nitro-1,4-dihydroquinoxaline-2,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL298284; SCHEMBL3668151; SCHEMBL3681753; BDBM50056601; 7-Methyl-5-nitro-1,4-dihydro-quinoxaline-2,3-dione
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| Activity |
IC50 = 107151930.5 nM
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[5] | |||
| Compound Name |
1,5-Naphthyridin-2(1H)-one, 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-
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Investigative | Compound Info | ||
| Synonyms |
ACEA-762; UNII-C54FJ3ZSAN; C54FJ3ZSAN; CHEMBL41291; SCHEMBL8692957; Q27275202; 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1H-1,5-naphthyridin-2-one
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| Activity |
IC50 = 109647819.6 nM
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[5] | |||
| Compound Name |
2,3-Quinoxalinedione, 7-chloro-6-ethyl-1,4-dihydro-5-nitro-
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL40745; SCHEMBL7466237; SCHEMBL8123618; 7-chloro-6-ethyl-5-nitro-1,4-dihydroquinoxaline-2,3-dione; BDBM50056592; 1,4-dihydro-7-chloro-6-ethyl-5-nitroquinoxalin-2,3-dione; 7-Chloro-6-ethyl-5-nitro-1,4-dihydro-quinoxaline-2,3-dione
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| Activity |
IC50 = 128824955.2 nM
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[5] | |||
| Compound Name |
7-Chloro-4-hydroxy-3-(3-nitrophenyl)-1H-1,5-naphthyridin-2-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL42805
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| Activity |
IC50 = 134896288.3 nM
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[5] | |||
| Compound Name |
7-Chloro-6-methoxy-5-nitro-1,4-dihydroquinoxaline-2,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL42466; SCHEMBL7352780; SCHEMBL8115133; BDBM50056621; 7-Chloro-6-methoxy-5-nitro-1,4-dihydro-quinoxaline-2,3-dione
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| Activity |
IC50 = 151356124.8 nM
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[5] | |||
| Compound Name |
5-Amino-6-methyl-7-chloroquinoxaline-2,3(1H,4H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL295995; SCHEMBL7786483; SCHEMBL8121811; 5-amino-7-chloro-6-methyl-1,4-dihydroquinoxaline-2,3-dione; BDBM50056615; 5-Amino-7-chloro-1,4-dihydro-6-methylquinoxaline-2,3-dione; 5-Amino-7-chloro-6-methyl-1,4-dihydro-quinoxaline-2,3-dione
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| Activity |
IC50 = 151356124.8 nM
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[5] | |||
| Compound Name |
2,3-Quinoxalinedione, 6,7-diethyl-1,4-dihydro-5-nitro-
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL41295; SCHEMBL7786413; SCHEMBL8123143; 6,7-diethyl-5-nitro-1,4-dihydroquinoxaline-2,3-dione; BDBM50056606; 5-Nitro-6,7-diethylquinoxaline-2,3(1H,4H)-dione; 5-Nitro-6,7-diethyl-1,4-dihydroquinoxaline-2,3-dione; 6,7-Diethyl-5-nitro-1,4-dihydro-quinoxaline-2,3-dione
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| Activity |
IC50 = 158489319.3 nM
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[5] | |||
| Compound Name |
5,6-Dichloro-3-(hydroxyimino)quinoline-2,4(1H,3H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL40708; SCHEMBL7048273; BDBM50052621; 5,6-Dichloro-1H-quinoline-2,3,4-trione 3-oxime; 5,6-dichloro-3-hydroxyimino-1H-quinoline-2,4-dione
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| Activity |
IC50 = 169824365.3 nM
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[5] | |||
| Compound Name |
4-Hydroxy-3-(3-phenoxyphenyl)-1H-1,7-naphthyridin-2-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL41501
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| Activity |
IC50 = 186208713.7 nM
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[5] | |||
| Compound Name |
3-Nitro-4-hydroxy-5,6,7-trichloroquinolin-2(1H)-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL42176; SCHEMBL8896128; 5,6,7-Trichloro-4-hydroxy-3-nitro-1H-quinolin-2-one
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| Activity |
IC50 = 218776162.4 nM
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[5] | |||
| Compound Name |
3-Nitro-4-hydroxy-5,7-dichloroquinolin-2(1H)-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL291161; SCHEMBL8897371; 5,7-Dichloro-4-hydroxy-3-nitro-1H-quinolin-2-one; 5,7-dichloro-3-nitro-4-hydroxy-1,2-dihydroquinolin-2-one
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| Activity |
IC50 = 218776162.4 nM
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[5] | |||
| Compound Name |
5-Chloroquinoline-2,3,4(1H)-trione 3-oxime
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL42057; BDBM50052634; 5-Chloro-1H-quinoline-2,3,4-trione 3-oxime
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| Activity |
IC50 = 229086765.3 nM
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[5] | |||
| Compound Name |
6-Butoxy-7-fluoro-5-nitro-1,4-dihydroquinoxaline-2,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL43122; SCHEMBL7779416; SCHEMBL8114124; BDBM50056624; 6-Butoxy-7-fluoro-5-nitro-1,4-dihydro-quinoxaline-2,3-dione
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| Activity |
IC50 = 234422881.5 nM
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[5] | |||
| Compound Name |
7-Chloro-4-hydroxy-3-thiophen-3-yl-1H-1,5-naphthyridin-2-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL289167
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| Activity |
IC50 = 234422881.5 nM
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[5] | |||
| Compound Name |
7-Fluoro-5-nitro-6-(3-phenylpropoxy)-1,4-dihydroquinoxaline-2,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL42307; SCHEMBL7784775; SCHEMBL8121105; BDBM50056617; 7-Fluoro-5-nitro-6-(3-phenyl-propoxy)-1,4-dihydro-quinoxaline-2,3-dione
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| Activity |
IC50 = 251188643.2 nM
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[5] | |||
| Compound Name |
5-Nitro-6-ethoxy-7-fluoroquinoxaline-2,3(1H,4H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL44018; SCHEMBL7779770; SCHEMBL8124073; 6-ethoxy-7-fluoro-5-nitro-1,4-dihydroquinoxaline-2,3-dione; BDBM50056616; 7-Fluoro-6-ethoxy-5-nitro-1,4dihydroquinoxaline-2,3-dione; 6-Ethoxy-7-fluoro-5-nitro-1,4-dihydro-quinoxaline-2,3-dione; 7-Fluoro-6-ethoxy-5-nitro-1,4-dihydroquinoxaline-2,3-dione
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| Activity |
IC50 = 275422870.3 nM
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[5] | |||
| Compound Name |
2(1H)-Quinolinone, 4-hydroxy-5,7-dimethyl-3-nitro-
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL41340; SCHEMBL8897751; 3-Nitro-4-hydroxy-5,7-dimethylquinolin-2(1H)-one; 4-Hydroxy-5,7-dimethyl-3-nitro-1H-quinolin-2-one
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| Activity |
IC50 = 288403150.3 nM
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[5] | |||
| Compound Name |
6-Chloroquinoline-2,3,4(1H)-trione 3-oxime
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL43318; BDBM50052628; 6-Chloro-1H-quinoline-2,3,4-trione 3-oxime
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| Activity |
IC50 = 295120922.7 nM
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[5] | |||
| Compound Name |
6,7-Dimethylquinoxaline-2,3-diol
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Investigative | Compound Info | ||
| Synonyms |
2,3-Dihydroxy-6,7-dimethylquinoxaline; 6,7-dimethyl-1,4-dihydroquinoxaline-2,3-dione; CHEMBL22720; 6,7-dimethylquinoxaline-2,3(1H,4H)-dione; 6,7-dimethyl-2,3-quinoxalinediol; 6,7-Dimethyl-1,4-dihydro-quinoxaline-2,3-dione; 6,7-dimethyl-1,2,3,4-tetrahydroquinoxaline-2,3-dione; NSC62694; Oprea1_492006; Oprea1_683541; SCHEMBL121942; SCHEMBL8128045; CTK4F4299; DTXSID20289673; 2, 1,4-dihydro-6,7-dimethyl-; BDBM50008768; MFCD00085437; NSC-62694; STK508297; STL507438; ZINC15020542; AKOS000446079; AKOS006241275; CCG-321640; MCULE-5863879166; AS-67593; ST053486; EU-0048704; FT-0609664; 1,4-Dihydro-6,7-dimethylquinoxalin-2,3-dione; 2,3-Quinoxalinedione,1,4-dihydro-6,7-dimethyl-; AE-641/14714015; 6,7-Dimethyl-1,4-dihydro-2,3-quinoxalinedione #; J-507024; F0918-4877; 1,2,3,4-Tetrahydroquinoxalin-2,3-dione, 6,7-dimethyl-
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| Activity |
IC50 = 301995172 nM
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[5] | |||
| Compound Name |
7-Chloro-4-hydroxy-3-phenyl-1H-1,5-naphthyridin-2-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL295084; ZINC29391321
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| Activity |
IC50 = 301995172 nM
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[5] | |||
| Compound Name |
5,6,7,8-Tetrafluoroquinoline-2,3,4(1H)-trione 3-oxime
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL291170; BDBM50052622; 5,6,7,8-Tetrafluoro-1H-quinoline-2,3,4-trione 3-oxime
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| Activity |
IC50 = 301995172 nM
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[5] | |||
| Compound Name |
5-Nitro-4,6,7,8-tetrahydro-1H-cyclopenta[g]quinoxaline-2,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL296521; BDBM50056602
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| Activity |
IC50 = 323593656.9 nM
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[5] | |||
| Compound Name |
7-Chloro-3-(3-chlorophenyl)-4-hydroxy-1H-1,5-naphthyridin-2-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL41180
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| Activity |
IC50 = 331131121.5 nM
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[5] | |||
| Compound Name |
7-Chloro-4-hydroxy-3-(3-methoxyphenyl)-1H-1,5-naphthyridin-2-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL297310; SCHEMBL8693246
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| Activity |
IC50 = 346736850.5 nM
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[5] | |||
| Compound Name |
8-Nitro-2,3-dioxo-1,4-dihydroquinoxaline-6-carbonitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL290747; SCHEMBL3671568; SCHEMBL3686797; BDBM50056594; 8-Nitro-2,3-dioxo-1,2,3,4-tetrahydro-quinoxaline-6-carbonitrile
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| Activity |
IC50 = 354813389.2 nM
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[5] | |||
| Compound Name |
6,7-Dichloro-4-hydroxy-3-nitroquinolin-2(1H)-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL41341; SCHEMBL8895544; 6,7-Dichloro-4-hydroxy-3-nitro-1H-quinolin-2-one; 6, 7-Dichloro-3-nitro-4-hydroxy-1,2-dihydroquinolin-2-one
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| Activity |
IC50 = 398107170.6 nM
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[5] | |||
| Compound Name |
5,7-Dimethyl-1,4-dihydroquinoxaline-2,3-dione
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Investigative | Compound Info | ||
| Synonyms |
5,7-dimethylquinoxaline-2,3-diol; CHEMBL296068; 2,3-Quinoxalinedione, 1,4-dihydro-5,7-dimethyl-; 5,7-Dimethyl-quinoxaline-2,3-diol; Cambridge id 5648449; Oprea1_154566; Oprea1_223937; Oprea1_555683; MLS000077267; SCHEMBL7784329; SCHEMBL8123065; CTK2D0901; DTXSID90349617; HMS2423H16; BDBM50052623; STK762700; STL431816; ZINC12410487; AKOS000442335; AKOS005616229; MCULE-7676495849; SMR000010954; ST4055041; 5,7-Dimethylquinoxaline-2,3(1H,4H)-dione; 5,7-dimethyl-1,4-dihydro-2,3-quinoxalinedione; 5,7-Dimethyl-1,4-dihydro-quinoxaline-2,3-dione; SR-01000529394; SR-01000529394-1; 5,7-dimethyl-1,2,3,4-tetrahydroquinoxaline-2,3-dione
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| Activity |
IC50 = 478630092.3 nM
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[5] | |||
| Compound Name |
7-Fluoro-6-methoxy-5-nitro-1,4-dihydroquinoxaline-2,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL40649; SCHEMBL7351103; SCHEMBL8120382; BDBM50056610; 5-Nitro-6-methoxy-7-fluoroquinoxaline-2,3(1H,4H)-dione; 7-Fluoro-6-methoxy-5-nitro-1,4-dihydro-quinoxaline-2,3-dione
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| Activity |
IC50 = 524807460.3 nM
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[5] | |||
| Compound Name |
6,7-Diethyl-1,4-dihydroquinoxaline-2,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL44260; SCHEMBL8090341; BDBM50056623; 6,7-Diethylquinoxaline-2,3(1H,4H)-dione; 6,7-Diethyl-1,4-dihydro-quinoxaline-2,3-dione
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| Activity |
IC50 = 549540873.9 nM
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[5] | |||
| Compound Name |
7-Chloro-4-hydroxy-3-(3-methylphenyl)-1H-1,5-naphthyridin-2-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL42694
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| Activity |
IC50 = 562341325.2 nM
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[5] | |||
| Compound Name |
6-Chloro-5,7-difluoro-1,4-dihydroquinoxaline-2,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL42329; SCHEMBL7346405; SCHEMBL8114807; BDBM50052624; 6,8-Difluoro-7-chloroquinoxaline-2,3(1H,4H)-dione; 6-Chloro-5,7-difluoro-1,4-dihydro-quinoxaline-2,3-dione
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| Activity |
IC50 = 630957344.5 nM
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[5] | |||
| Compound Name |
7-Chloro-6-ethylsulfanyl-5-nitro-1,4-dihydro-quinoxaline-2,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL41399; SCHEMBL7779811; SCHEMBL8121823; 7-chloro-6-ethylsulfanyl-5-nitro-1,4-dihydroquinoxaline-2,3-dione; BDBM50056593; 7-Chloro-1,4-dihydro-6-ethylthio-5-nitroquinoxaline-2,3-dione
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| Activity |
IC50 = 645654229 nM
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[5] | |||
| Compound Name |
7-Chloro-3-nitro-4-hydroxyquinolin-2(1H)-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL42350; SCHEMBL8898836; 7-Chloro-4-hydroxy-3-nitrocarbostyril; 3-Nitro-4-hydroxy-7-chloroquinolin-2(1H)-one; 7-Chloro-4-hydroxy-3-nitro-1H-quinolin-2-one
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| Activity |
IC50 = 660693448 nM
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[5] | |||
| Compound Name |
3-Hydroxyimino-1H-quinoline-2,4-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL42071; NSC97341; 1,2,3,4-tetrahydroquinoline-2,3,4-trione 3-oxime; (3E)-3-hydroxyimino-1H-quinoline-2,4-dione; (3Z)-3-hydroxyimino-1H-quinoline-2,4-dione; 3-nitrosoquinoline-2,4-diol; 3-Nitroso-2,4-quinolinediol; 3-Oximinoquinolin-2,4-dione; 3-nitroso-4-hydroxycarbostyril; SCHEMBL3283059; SCHEMBL7050064; SCHEMBL8874278; BDBM50052636; NSC-97341; ZINC17014699; 1H-Quinoline-2,3,4-trione 3-oxime; AKOS024325855; ZINC100775788; MCULE-3388467334; Quinoline-2,3,4(1H)-trione 3-oxime; (3Z)-2,3,4(1H)-quinolinetrione 3-oxime; 2,4-Quinolinediol, 3-nitroso- (keto form); 1,2,3,4-tetrahydroquinoline-2,3,4-trione-3-oxime
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| Activity |
IC50 = 707945784.4 nM
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[5] | |||
| Compound Name |
6-Chloro-7-ethyl-1,4-dihydroquinoxaline-2,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL42482; SCHEMBL7469933; SCHEMBL8128202; BDBM50056613; 6-Chloro-7-ethylquinoxaline-2,3(1H,4H)-dione; 1,4-Dihydro-6-chloro-7-ethylquinoxalin-2,3-dione; 6-Chloro-7-ethyl-1,4-dihydro-quinoxaline-2,3-dione
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| Activity |
IC50 = 707945784.4 nM
|
[5] | |||
| Compound Name |
5,6,7,8-Tetrafluoro-1,4-dihydro-2,3-quinoxalinedione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL289779; SCHEMBL2639786; SCHEMBL8123612; BDBM50052630; 5,6,7,8-Tetrafluoroquinoxaline-2,3(1H,4H)-dione; 5,6,7,8-tetrafluoro-1,4-dihydroquinoxaline-2,3-dione; 5,6,7,8-Tetrafluoro-1,4-dihydro-quinoxaline-2,3-dione
Click to Show/Hide
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| Activity |
IC50 = 724435960.1 nM
|
[5] | |||
| Compound Name |
6-Chloro-7-methyl-1,4-dihydroquinoxaline-2,3-dione
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL288384; SCHEMBL5769722; BDBM50056622; 6-chloro-7-methyl-2,3(1H, 4H)-quinoxalinedione; 1,4-dihydro-6-chloro-7-methylquinoxalin-2,3-dione; 6-Chloro-7-methyl-1,4-dihydro-quinoxaline-2,3-dione
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| Activity |
IC50 = 776247116.6 nM
|
[5] | |||
| Compound Name |
6,8-Difluoro-7-chloroquinoline-2,3,4(1H)-trione 3-oxime
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL291169; BDBM50052633; 7-Chloro-6,8-difluoro-1H-quinoline-2,3,4-trione 3-oxime
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| Activity |
IC50 = 912010839.4 nM
|
[5] | |||
| Compound Name |
7-Bromo-6-methoxy-1,4dihydroquinoxaline-2,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL553334; BDBM50056614; 6-Bromo-7-methoxy-1,4-dihydro-quinoxaline-2,3-dione
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| Activity |
IC50 = 1000000000 nM
|
[5] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | N-sulfonyl derivatives of 6,7-dichloro 3,4-dihydro-3-oxo-quinoxalinecarboxylate as glycine-site NMDA and AMPA antagonists. Bioorg Med Chem Lett. 1993 Jan;3(1):77-80. | ||||
| REF 2 | Aromatic analogs of arcaine inhibit MK-801 binding to the NMDA receptor. Bioorg Med Chem Lett. 1998 Dec 15;8(24):3459-64. | ||||
| REF 3 | Improving the inhibitory activity of arylidenaminoguanidine compounds at the N-methyl-D-aspartate receptor complex from a recursive computational-experimental structure-activity relationship study. Bioorg Med Chem. 2013 Apr 1;21(7):1764-74. | ||||
| REF 4 | NMDA-NR2B subtype selectivity of stereoisomeric 2-(1,2,3,4-tetrahydro-1-isoquinolyl)ethanol derivatives. Bioorg Med Chem Lett. 2005 May 2;15(9):2231-4. | ||||
| REF 5 | CoMFA and homology-based models of the glycine binding site of N-methyl-d-aspartate receptor. J Med Chem. 2003 Apr 24;46(9):1609-16. | ||||
| REF 6 | Chemical space as a source for new drugs. Medchemcomm. 2010;1:30-8. | ||||
| REF 7 | Heteroaryl analogues of AMPA. Synthesis and quantitative structure-activity relationships. J Med Chem. 1997 Aug 29;40(18):2831-42. | ||||
| REF 8 | Synthesis and structure-activity relationships of N,N'-di-o-tolylguanidine analogues, high-affinity ligands for the haloperidol-sensitive sigma receptor. J Med Chem. 1990 Sep;33(9):2421-9. | ||||
| REF 9 | Tetrazole amino acids as competitive NMDA antagonists. Bioorg Med Chem Lett. 1993 Jan;3(1):43-8. | ||||
| REF 10 | Novel sigma receptor ligands 1.. Bioorg Med Chem Lett. 1993 Feb;3(2):215-20. | ||||
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