| References |
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| REF 1 |
Mechanistic relationship between androgen receptor polyglutamine tract truncation and androgen-dependent transcriptional hyperactivity in prostate cancer cells. J Biol Chem. 2004 Apr 23;279(17):17319-28.
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| REF 2 |
Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping. Mol Cell Proteomics. 2017 Aug;16(8):1462-1474.
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| REF 3 |
Functional screening of FxxLF-like peptide motifs identifies SMARCD1/BAF60a as an androgen receptor cofactor that modulates TMPRSS2 expression. Mol Endocrinol. 2009 Nov;23(11):1776-86.
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| REF 4 |
Prohibitin and the SWI/SNF ATPase subunit BRG1 are required for effective androgen antagonist-mediated transcriptional repression of androgen receptor-regulated genes. Carcinogenesis. 2008 Sep;29(9):1725-33.
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Suppression of androgen receptor transactivation and prostate cancer cell growth by heterogeneous nuclear ribonucleoprotein A1 via interaction with androgen receptor coregulator ARA54. Endocrinology. 2007 Mar;148(3):1340-9.
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The FXXLF motif mediates androgen receptor-specific interactions with coregulators. J Biol Chem. 2002 Mar 22;277(12):10226-35.
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Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor. J Biol Chem. 1999 Mar 26;274(13):8570-6.
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| REF 8 |
Expression of RAC 3, a steroid hormone receptor co-activator in prostate cancer. Br J Cancer. 2001 Dec 14;85(12):1928-36.
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Thyroid receptor activator molecule, TRAM-1, is an androgen receptor coactivator. Endocrinology. 2000 Sep;141(9):3440-50.
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Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination. Cancer Cell. 2009 Apr 7;15(4):270-82.
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Ring Finger Protein 6 Mediates Androgen-Induced Granulosa Cell Proliferation and Follicle Growth via Modulation of Androgen Receptor Signaling. Endocrinology. 2017 Apr 1;158(4):993-1004.
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The neuroendocrine-derived peptide parathyroid hormone-related protein promotes prostate cancer cell growth by stabilizing the androgen receptor. Cancer Res. 2009 Sep 15;69(18):7402-11.
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The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process. EMBO J. 2011 Feb 2;30(3):468-79.
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An androgen receptor NH2-terminal conserved motif interacts with the COOH terminus of the Hsp70-interacting protein (CHIP). J Biol Chem. 2004 Jul 16;279(29):30643-53.
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| REF 15 |
Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells. J Biol Chem. 2002 Oct 11;277(41):38087-94.
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A novel variant of the putative demethylase gene, s-JMJD1C, is a coactivator of the AR. Arch Biochem Biophys. 2007 Apr 1;460(1):56-66.
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| REF 17 |
Recruitment of beta-catenin by wild-type or mutant androgen receptors correlates with ligand-stimulated growth of prostate cancer cells. Mol Endocrinol. 2004 Oct;18(10):2388-401.
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| REF 18 |
PATZ attenuates the RNF4-mediated enhancement of androgen receptor-dependent transcription. J Biol Chem. 2002 Feb 1;277(5):3280-5.
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Identification of a novel RING finger protein as a coregulator in steroid receptor-mediated gene transcription. Mol Cell Biol. 1998 Sep;18(9):5128-39.
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p300 acetyltransferase regulates androgen receptor degradation and PTEN-deficient prostate tumorigenesis. Cancer Res. 2014 Mar 15;74(6):1870-1880.
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p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation. J Biol Chem. 2000 Jul 7;275(27):20853-60.
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| REF 22 |
TRIM24 mediates ligand-dependent activation of androgen receptor and is repressed by a bromodomain-containing protein, BRD7, in prostate cancer cells. Biochim Biophys Acta. 2009 Dec;1793(12):1828-36.
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| REF 23 |
Differential interaction of nuclear receptors with the putative human transcriptional coactivator hTIF1. J Biol Chem. 1997 May 2;272(18):12062-8.
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Multifunction steroid receptor coactivator, E6-associated protein, is involved in development of the prostate gland. Mol Endocrinol. 2006 Mar;20(3):544-59.
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| REF 25 |
Identification of a novel K311 ubiquitination site critical for androgen receptor transcriptional activity. Nucleic Acids Res. 2017 Feb 28;45(4):1793-1804.
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Ubiquitylation of epsilon-COP by PIRH2 and regulation of the secretion of PSA. Mol Cell Biochem. 2008 Jan;307(1-2):73-82.
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| REF 27 |
Cloning and characterization of an androgen receptor N-terminal-interacting protein with ubiquitin-protein ligase activity. J Mol Endocrinol. 2002 Aug;29(1):41-60.
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| REF 28 |
Suppression of androgen receptor transactivation by Pyk2 via interaction and phosphorylation of the ARA55 coregulator. J Biol Chem. 2002 May 3;277(18):15426-31.
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| REF 29 |
DDB2 is a novel AR interacting protein and mediates AR ubiquitination/degradation. Int J Biochem Cell Biol. 2012 Nov;44(11):1952-61.
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| REF 30 |
NRIP/DCAF6 stabilizes the androgen receptor protein by displacing DDB2 from the CUL4A-DDB1 E3 ligase complex in prostate cancer. Oncotarget. 2017 Mar 28;8(13):21501-21515.
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| REF 31 |
Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation. Nucleic Acids Res. 2005 Jan 7;33(1):13-26.
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| REF 32 |
Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor. J Biol Chem. 2002 Jul 19;277(29):25904-13.
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| REF 33 |
Inhibition of androgen receptor activity by histone deacetylase 4 through receptor SUMOylation. Oncogene. 2011 May 12;30(19):2207-18.
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| REF 34 |
Interaction of nuclear receptor zinc finger DNA binding domains with histone deacetylase. Mol Cell Endocrinol. 2003 Aug 29;206(1-2):1-12.
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| REF 35 |
Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway. Cell. 2006 Feb 10;124(3):615-29.
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| REF 36 |
A central domain of cyclin D1 mediates nuclear receptor corepressor activity. Oncogene. 2005 Jan 13;24(3):431-44.
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| REF 37 |
Cooperative interactions between androgen receptor (AR) and heat-shock protein 27 facilitate AR transcriptional activity. Cancer Res. 2007 Nov 1;67(21):10455-65.
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| REF 38 |
Association of the 90-kDa heat shock protein does not affect the ligand-binding ability of androgen receptor. J Steroid Biochem Mol Biol. 1992 Sep;42(8):803-12.
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| REF 39 |
Androgen receptor specifically interacts with a novel p21-activated kinase, PAK6. J Biol Chem. 2001 May 4;276(18):15345-53.
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| REF 40 |
AR and ER interaction with a p21-activated kinase (PAK6). Mol Endocrinol. 2002 Jan;16(1):85-99.
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| REF 41 |
Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7200-5.
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| REF 42 |
From androgen receptor to the general transcription factor TFIIH. Identification of cdk activating kinase (CAK) as an androgen receptor NH(2)-terminal associated coactivator. J Biol Chem. 2000 Mar 31;275(13):9308-13.
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| REF 43 |
Identification and characterization of a novel androgen receptor coregulator ARA267-alpha in prostate cancer cells. J Biol Chem. 2001 Nov 2;276(44):40417-23.
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| REF 44 |
A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors. Nucleic Acids Res. 2013 Nov;41(21):9663-79.
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| REF 45 |
The mutational landscape of lethal castration-resistant prostate cancer. Nature. 2012 Jul 12;487(7406):239-43.
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| REF 46 |
CACUL1 functions as a negative regulator of androgen receptor in prostate cancer cells. Cancer Lett. 2016 Jul 1;376(2):360-6.
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| REF 47 |
Regulation of androgen receptor activity by the nuclear receptor corepressor SMRT. J Biol Chem. 2003 Feb 14;278(7):5052-61.
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| REF 48 |
Electrostatic modulation in steroid receptor recruitment of LXXLL and FXXLF motifs. Mol Cell Biol. 2003 Mar;23(6):2135-50.
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| REF 49 |
p54nrb acts as a transcriptional coactivator for activation function 1 of the human androgen receptor. Biochem Biophys Res Commun. 2003 Jul 4;306(3):660-5.
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| REF 50 |
Antiandrogen effects of mifepristone on coactivator and corepressor interactions with the androgen receptor. Mol Endocrinol. 2004 Jan;18(1):70-85.
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| REF 51 |
Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor. Mol Endocrinol. 2002 Jul;16(7):1492-501.
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| REF 52 |
Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor. Cancer Cell. 2010 Jun 15;17(6):535-46.
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| REF 53 |
CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1. J Biol Chem. 1998 Nov 27;273(48):31853-9.
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| REF 54 |
The role of protein kinase A pathway and cAMP responsive element-binding protein in androgen receptor-mediated transcription at the prostate-specific antigen locus. J Mol Endocrinol. 2005 Feb;34(1):107-18.
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| REF 55 |
The androgen receptor represses transforming growth factor-beta signaling through interaction with Smad3. J Biol Chem. 2002 Jan 11;277(2):1240-8.
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| REF 56 |
SMAD3 represses androgen receptor-mediated transcription. Cancer Res. 2001 Mar 1;61(5):2112-8.
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| REF 57 |
Tumor suppressor PAX6 functions as androgen receptor co-repressor to inhibit prostate cancer growth. Prostate. 2010 Feb 1;70(2):190-9.
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| REF 58 |
Pax6 represses androgen receptor-mediated transactivation by inhibiting recruitment of the coactivator SPBP. PLoS One. 2011;6(9):e24659.
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| REF 59 |
Cross-talk between signal transducer and activator of transcription 3 and androgen receptor signaling in prostate carcinoma cells. Biochem Biophys Res Commun. 2001 Apr 27;283(1):179-87.
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| REF 60 |
Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways. J Biol Chem. 2002 Mar 1;277(9):7076-85.
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| REF 61 |
Zipper-interacting protein kinase is involved in regulation of ubiquitination of the androgen receptor, thereby contributing to dynamic transcription complex assembly. Oncogene. 2013 Oct 10;32(41):4981-8.
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| REF 62 |
Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins. EMBO J. 1999 Oct 1;18(19):5380-8.
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| REF 63 |
Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells. Proc Natl Acad Sci U S A. 1996 May 28;93(11):5517-21.
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| REF 64 |
Interaction of the putative androgen receptor-specific coactivator ARA70/ELE1alpha with multiple steroid receptors and identification of an internally deleted ELE1beta isoform. Mol Endocrinol. 1999 Jan;13(1):117-28.
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| REF 65 |
Melanoma antigen gene protein MAGE-11 regulates androgen receptor function by modulating the interdomain interaction. Mol Cell Biol. 2005 Feb;25(4):1238-57.
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| REF 66 |
A direct beta-catenin-independent interaction between androgen receptor and T cell factor 4. J Biol Chem. 2003 Aug 15;278(33):30828-34.
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| REF 67 |
Destruction of full-length androgen receptor by wild-type SPOP, but not prostate-cancer-associated mutants. Cell Rep. 2014 Feb 27;6(4):657-69.
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| REF 68 |
Regulation of the transcriptional activation of the androgen receptor by the UXT-binding protein VHL. Biochem J. 2013 Nov 15;456(1):55-66.
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| REF 69 |
The von hippel-lindau protein suppresses androgen receptor activity. Mol Endocrinol. 2014 Feb;28(2):239-48.
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| REF 70 |
NRIP, a novel nuclear receptor interaction protein, enhances the transcriptional activity of nuclear receptors. J Biol Chem. 2005 May 20;280(20):20000-9.
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| REF 71 |
Targeting the BAF57 SWI/SNF subunit in prostate cancer: a novel platform to control androgen receptor activity. Cancer Res. 2008 Jun 15;68(12):4551-8.
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