Protein-Protein Interaction Details
Protein General Information (TTD Target) | Top | ||||
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Full Name | Renal carcinoma antigen NY-REN-54 (UBE3A) | Literature-reported | Target Info | ||
UniProt ID | UBE3A_HUMAN | ||||
Gene Name | UBE3A | ||||
Gene ID | 7337 |
Interacting TTD Target Information | Top | ||||
---|---|---|---|---|---|
Interacting Successful Target(s) | Androgen receptor (AR) | Target Info | PPI Info | [1] | |
Interacting Clinical trial Target(s) | Cellular tumor antigen p53 (TP53) | Target Info | PPI Info | [2] | |
Interacting Patented-recorded Target(s) | Proteasome beta-2 (PS beta-2) | Target Info | PPI Info | [3] | |
Proteasome beta-5 (PS beta-5) | Target Info | PPI Info | [3] | ||
Proteasome beta-1 (PS beta-1) | Target Info | PPI Info | [3] | ||
Ubiquitin C-terminal hydrolase UCH37 (UCHL5) | Target Info | PPI Info | [3] | ||
Interacting Preclinical Target(s) | Ubiquitin carboxyl-terminal hydrolase 14 (USP14) | Target Info | PPI Info | [4] | |
Interacting Literature-reported Target(s) | Renal carcinoma antigen NY-REN-54 (UBE3A) | Target Info | PPI Info | [3] |
References | Top | ||||
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REF 1 | Multifunction steroid receptor coactivator, E6-associated protein, is involved in development of the prostate gland. Mol Endocrinol. 2006 Mar;20(3):544-59. | ||||
REF 2 | Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53. Nature. 2016 Jan 28;529(7587):541-5. | ||||
REF 3 | Identification and proteomic analysis of distinct UBE3A/E6AP protein complexes. Mol Cell Biol. 2012 Aug;32(15):3095-106. | ||||
REF 4 | Network Analysis of UBE3A/E6AP-Associated Proteins Provides Connections to Several Distinct Cellular Processes. J Mol Biol. 2018 Mar 30;430(7):1024-1050. |
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