Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| Cathepsin K --- MEP | [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid (1S,3S,5R)-3,5-dimethyl-cyclohexyl ester | Drug Info |
| Cathepsin K --- MEP | N-((S)-3-(7,7-dimethylbicyclo[2.2.1]heptan-1-yl)-1-((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)-1-oxopropan-2-yl)morpholine-4-carboxamide | Drug Info |
| Cathepsin K --- MEP | benzyl (S)-1-oxo-1-((3R,4R)-2-oxo-4-phenoxyazetidin-3-ylamino)-3-phenylpropan-2-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | (S)-N-((S)-1-(5-(furan-2-yl)-1,3,4-oxadiazol-2-yl)-1-oxopentan-2-yl)-4-methyl-2-(2,2,2-trifluoroethylamino)pentanamide | Drug Info |
| Cathepsin K --- MEP | (R)-2-{3'-[2-(4-tert-butyl-piperazin-1-yl)-thiazol-4-yl]-biphenyl-3-yl}-4-methyl-pentanoic acid cyanomethyl-amide | Drug Info |
| Cathepsin K --- MEP | N-((S)-3-cyclohexyl-1-((S)-1-(5-fluoroindolin-1-yl)propan-2-ylamino)-1-oxopropan-2-yl)morpholine-4-carboxamide | Drug Info |
| Cathepsin K --- MEP | 2',3',4'-trifluoro-biphenyl-2-yloxy-acetaldehyde | Drug Info |
| Cathepsin K --- MEP | (S)-N-(3-cyclohexyl-1-oxo-1-(2-(4-(trifluoromethoxy)phenylamino)ethylamino)propan-2-yl)furan-3-carboxamide | Drug Info |
| Cathepsin K --- MEP | (S)-3-cyclohexyl-1-morpholino-1-oxopropan-2-yl (S)-4-phenyl-1-(4-(trifluoromethoxy)phenylamino)butan-2-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | (S)-3,3-dimethyl-1-(4-(4-(trifluoromethyl)phenyl)-1H-imidazol-1-yl)butan-2-yl(S)-1-(1H-pyrazol-5-ylamino)-1,2-dioxoheptan-3-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | {(S)-1-[2-(4-Cyclopentyloxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | 6-Cyclohexylamino-9-{2-[(2-methoxy-ethyl)-methyl-amino]-ethyl}-9H-purine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid adamantan-2-yl ester | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-(2,2-dimethyl-propylamino)-pyrimidine-5-carboxylic acid {2-[4-(2-imidazol-1-yl-ethoxy)-phenyl]-ethyl}-amide | Drug Info |
| Cathepsin K --- MEP | 4-(3-Cyano-benzenesulfonylamino)-N-[1-(2S-ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-benzamide | Drug Info |
| Cathepsin K --- MEP | (S)-N-(3-(3-chlorophenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)-2,5-dimethyloxazole-4-carboxamide | Drug Info |
| Cathepsin K --- MEP | (S)-3-tert-butyl-N-(1-(cyanomethylamino)-3-(3-(5-methyl-1,3,4-thiadiazol-2-yl)phenyl)-1-oxopropan-2-yl)-1-methyl-1H-pyrazole-5-carboxamide | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((S)-3-Hydroxy-2-oxo-1-phenethyl-propylcarbamoyl)-2-methyl-butyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | N-((S)-3-cyclopentyl-1-oxo-1-((S)-1-(4-(trifluoromethoxy)phenylamino)propan-2-ylamino)propan-2-yl)morpholine-4-carboxamide | Drug Info |
| Cathepsin K --- MEP | (1-phenethylcyclobutyl)methyl(S)-1,2-dioxo-1-((R)-1-phenylethylamino)heptan-3-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | 6-(4-chlorobenzyl)-7-(3,3-dimethylbutyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | (S)-N-(3-(3-(1,3,4-thiadiazol-2-yl)phenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)benzamide | Drug Info |
| Cathepsin K --- MEP | Benzoic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-4-oxo-azetidin-2-yl ester | Drug Info |
| Cathepsin K --- MEP | (R)-2-(cyclohexylmethyl)-4-morpholino-4-oxo-N-((S)-4-phenyl-1-(4-(trifluoromethoxy)phenylamino)butan-2-yl)butanamide | Drug Info |
| Cathepsin K --- MEP | (R,S)-4-methyl-2-{3'-[2-(4-methyl-piperazin-1-yl)-thiazol-4-yl]-biphenyl-3-yl}-pentanoic acid cyanomethyl-amide | Drug Info |
| Cathepsin K --- MEP | (S)-N-(3-cyclohexyl-1-oxo-1-(2-(4-(trifluoromethoxy)phenylamino)ethylamino)propan-2-yl)benzofuran-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | 4-Methyl-2-(3-pyridin-3-yl-phenyl)-pentanoic acid cyanomethyl-amide | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-((cyclohexylmethyl)(methyl)amino)-N-phenethylpyrimidine-5-carboxamide | Drug Info |
| Cathepsin K --- MEP | [3-Methyl-1-(3-oxo-tetrahydro-pyran-4-ylcarbamoyl)-butyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | {(S)-1-[(S)-1-Benzyl-2-(biphenyl-4-ylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | (S)-3-cyclohexyl-1-morpholino-1-oxopropan-2-yl (S)-1-(4-(trifluoromethoxy)phenylamino)pentan-2-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | 5-Methyl-1-phenyl-1H-pyrazole-4-carboxylic acid {(S)-2-cyclohexyl-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-ethyl}-amide | Drug Info |
| Cathepsin K --- MEP | (S)-N-(1-(2-(4-methoxy-3,5-dimethylphenylamino)ethylamino)-4-methyl-1-oxopentan-2-yl)-3-methylbenzamide | Drug Info |
| Cathepsin K --- MEP | 6-[4-(4-Acetyl-piperazin-1-yl)-2-fluoro-phenoxymethyl]-7-(2-cyclohexyl-ethyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | N-((S)-3-cyclohexyl-1-oxo-1-((S)-1-(4-(trifluoromethoxy)phenylamino)propan-2-ylamino)propan-2-yl)morpholine-4-carboxamide | Drug Info |
| Cathepsin K --- MEP | N-((S)-1-((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)-3-(1-methylcyclopentyl)-1-oxopropan-2-yl)furan-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | SID14739111 | Drug Info |
| Cathepsin K --- MEP | 2-Cyano-4-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrimidine-5-carboxylic acid (1-methyl-4-phenyl-piperidin-4-ylmethyl)-amide | Drug Info |
| Cathepsin K --- MEP | N-((S)-3-cyclohexyl-1-((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)-1-oxopropan-2-yl)furan-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | N-((S)-4-methyl-1-((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)-1-oxopentan-2-yl)furan-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | 3-Phenyl-propionic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-4-oxo-azetidin-2-yl ester | Drug Info |
| Cathepsin K --- MEP | N-[1-(2S-Ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-4-(pyridine-3-sulfonylamino)-benzamide | Drug Info |
| Cathepsin K --- MEP | N-[1-((S)-(S)-4-Benzoyl-6-(S)-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl)-3-methyl-butyl]-4-dimethylamino-benzamide | Drug Info |
| Cathepsin K --- MEP | 6-(4-chlorobenzyl)-7-phenethyl-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | (R,S)-4-methyl-2-[4'-(2-piperazin-1-yl-thiazol-4-yl)-biphenyl-3-yl]-pentanoic acid cyanomethyl-amide | Drug Info |
| Cathepsin K --- MEP | 6-[4-(4-Acetyl-piperazin-1-yl)-phenoxymethyl]-7-[2-(4,4-difluoro-cyclohexyl)-ethyl]-7Hpyrrolo[2,3-d]pyrimidine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | 2-Cyano-4-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrimidine-5-carboxylic acid ((S)-1-benzyl-2-pyrrolidin-1-yl-ethyl)-amide | Drug Info |
| Cathepsin K --- MEP | benzyl (S)-1-((R)-2-(benzyloxy)-1-cyanoethylamino)-4-methyl-1-oxopentan-2-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((S)-3-Benzyloxy-2-oxo-1-phenethyl-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | 2,2-dimethyl-3-phenylpropyl(S)-1,2-dioxo-1-((R)-1-phenylethylamino)heptan-3-ylcarbamate | Drug Info |
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