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| Protein General Information |
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| Full Name |
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B)
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| UniProt ID |
BUB1B_HUMAN
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| Gene Name |
BUB1B
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| Gene ID |
701
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| Interacting TTD Target Information |
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| Interacting Clinical trial Target(s) |
Polo-like kinase 1 (PLK1) |
Target Info
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PPI Info
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[1] |
| Interacting Patented-recorded Target(s) |
BUB1 mitotic checkpoint serine/threonine kinase (BUB1) |
Target Info
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PPI Info
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[2] |
| Interacting Literature-reported Target(s) |
Breast cancer type 2 susceptibility protein (BRCA2) |
Target Info
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PPI Info
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[3] |
| References |
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| REF 1 |
BubR1 localizes to centrosomes and suppresses centrosome amplification via regulating Plk1 activity in interphase cells. Oncogene. 2009 Aug 6;28(31):2806-20.
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| REF 2 |
Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science. 2010 Apr 30;328(5978):593-9.
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| REF 3 |
HDAC2/3 binding and deacetylation of BubR1 initiates spindle assembly checkpoint silencing. FEBS J. 2017 Dec;284(23):4035-4050.
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