Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T36059 | Target Info | |||
| Target Name | Adenosine A3 receptor (ADORA3) | ||||
| Synonyms |
Adenosine receptor A3A; Adenosine receptor A3; Adenosine 3 receptor; A3AR; A3 Adenosine receptor
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| Target Type | Clinical trial Target | ||||
| Gene Name | ADORA3 | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 103 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Enprofylline
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|
Approved | Compound Info | ||
| Synonyms |
Enprofilina; Enprofyllinum; Nilyph; Oxeze; P 5679; D-4028; Enprofilina [INN-Spanish]; Enprofylline [USAN:INN]; Enprofyllinum [INN-Latin]; Enprofylline (USAN/INN); 3,7-Dihydro-3-propyl-1H-purine-2,6-dione; 3-Propyl-3,7-dihydro-purine-2,6-dione; 3-Propylxanthine; 3-n-Propylxanthine; 3-propyl-3,7-dihydro-1H-purine-2,6-dione; 3-propyl-7H-purine-2,6-dione
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| Activity |
Ki = 92600 nM
|
[1] | |||
| Compound Name |
Flavanone
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Phase 1 | Compound Info | ||
| Synonyms |
FLAVANONE; 487-26-3; 2-Phenylchroman-4-one; 2,3-Dihydroflavone; 2-Phenyl-4-chromanone; 4-Flavanone; 2,3-Dihydro-2-phenyl-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 2,3-dihydro-2-phenyl-; 2-Phenyl-2,3-dihydro-4H-chromen-4-one; NSC-50393; 2,3-Dihydro-2-phenyl-4H-benzopyran-4-one; 2-Phenyl-chroman-4-one; 2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one; EINECS 207-654-8; NSC 50393; BRN 0183227; MLS002667384; CHEMBL274318; CHEBI:5070; ZONYXWQDUYMKFB-UHFFFAOYSA-N; NSC50393; 2-phenyl-2,3-dihydrochromen-4-one; MFCD00006841; (-)-Flavanone
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| Activity |
Ki = 50100 nM
|
[2] | |||
| Compound Name |
PMID28870136-Compound-48
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Patented | Compound Info | ||
| Activity |
Ki = 52300 nM
|
[3] | |||
| Compound Name |
PMID28870136-Compound-52
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Patented | Compound Info | ||
| Activity |
Ki ~ 100000 nM
|
[4] | |||
| Compound Name |
CGS-15943
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Investigative | Compound Info | ||
| Synonyms |
104615-18-1
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| Activity |
Ki = 84918.05 nM
|
[5] | |||
| Compound Name |
9-(sec-Butyl)-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL466044; 9-(sec-Butyl)-9H-adenine; SCHEMBL240049
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| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
8-Bromo-9-propyl-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL506450; 8-bromo-9-propyl-9H-purin-6-ylamine; 908355-66-8; 8-Bromo-9-propyl-9H-adenine; BDBM50256893; 8-Bromo-9-propyl-9H-purine-6-amine
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| Activity |
Ki ~ 100000 nM
|
[7] | |||
| Compound Name |
9-Benzyl-8-bromo-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
9-benzyl-8-bromoadenine; CHEMBL151071; 9-benzyl-8-bromo-9H-purin-6-amine; 56046-34-5; 9-Benzyl-8-bromo-9H-adenine; 8-bromo-9-benzyladenine; N9-benzyl-8-bromoadenine; 8-Bromo-N9-benzyladenine; SCHEMBL4341941; OUPAEJUFVKPEHM-UHFFFAOYSA-N; BDBM50240851; 6-Amino-8-bromo-9-benzyl-9H-purine; 9-Benzyl-8-bromo-9H-purin-6-ylamine; 9-benzyl-8-bromo-9H-purin-6-yl amine
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| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
(S)-DHPA
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Investigative | Compound Info | ||
| Synonyms |
S-Dihydroxypropyladenine; (S)-9-(2,3-Dihydroxypropyl)adenine; (S)-DHPA; 9-D-(2,3-Dihydroxypropyl)adenine; 54262-83-8; BRN 0990757; (2s)-3-(6-amino-9h-purin-9-yl)propane-1,2-diol; (2S)-3-(6-aminopurin-9-yl)propane-1,2-diol; (S)-3-(6-Amino-9H-purin-9-yl)-1,2-propanediol; 1,2-Propanediol, 3-(6-amino-9H-purin-9-yl)-, (S)-; 9-(S)-(2,3-Dihydroxypropyl)adenine; AC1Q4VGK; DHPA, (S)-DHPA; AC1L2JB5; 5-26-16-00201 (Beilstein Handbook Reference); SCHEMBL936286; CHEMBL494759; CTK5A0230; 9-(1,2-dihydroxypropyl)adenine; ZINC370772
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| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
9-Ethyl-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
9-ethyl-9h-purin-6-amine; 2715-68-6; 9-Ethyladenine; 9H-Purin-6-amine,9-ethyl; N9-Ethyladenine; 9-ethylpurin-6-amine; 9H-Purin-6-amine, 9-ethyl-; 9-ethyl adenine; 9-Ethyl-9H-purin-6-ylamine; 9H-Purin-6-amine,9-ethyl-; CHEMBL304009; Adenine, 9-ethyl-; 9-Ethyl-9H-adenine; N9 -ethyladenine; NSC 14580; 6-Amino-9-ethylpurine; AC1Q4VHH; ACMC-1CJP6; (9-ethylpurin-6-yl)amine; Adenine, 9-ethyl- (8CI); AC1L189M; SCHEMBL1924594; CTK4F9170; DTXSID50181616; MUIPLRMGAXZWSQ-UHFFFAOYSA-N; MolPort-004-964-357; ZINC402896; NSC14580; KS-000000ID
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| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
9-Methyl-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
9-Methyl-9H-purin-6-ylamine
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| Activity |
Ki ~ 100000 nM
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[6] | |||
| Compound Name |
9-Propyl-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
9-propyl-9h-purin-6-amine; CHEMBL475023; 707-98-2; 9-propyl-9H-purin-6-ylamine; 9-Propyl-9H-adenine; 9-propylpurin-6-amine; 9-propyladenine; NSC61961; AC1Q4VHN; AC1L6K9K; SCHEMBL233405; 9-Propyl-9H-purine-6-amine; CTK5D3013; DTXSID10289561; BDBM50256891; NSC-61961
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| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
9-Butyl-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
2715-70-0; 9-butyl-9H-purin-6-ylamine; 9H-Purin-6-amine, 9-butyl-; 9-Butyl-9H-purin-6-amine; 9H-Purin-6-amine, 9-butyl- (9CI); CHEMBL449628; 9-Butyl-9H-adenine; 9-butylpurin-6-amine; 9-butyladenine; NSC19094; NSC 19094; Adenine, 9-butyl-; AC1L2PTM; AC1Q4VHO; 9H-Purin-6-amine,9-butyl-; SCHEMBL1074972; CTK4F9171; DTXSID10181617; MolPort-011-342-029; BKXMJMZKKNIYRD-UHFFFAOYSA-N; ZINC1562338; NSC-19094; BDBM50256951; AKOS012922662; MCULE-9977877843; 9-Butyl-9H-purin-6-amine, AldrichCPR
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| Activity |
Ki ~ 100000 nM
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[6] | |||
| Compound Name |
7-Propyl-7H-adenine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL449108; 7-Propyl-7H-adenine; 7H-Purin-6-amine, 7-propyl-; BDBM50256892
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| Activity |
Ki ~ 100000 nM
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[6] | |||
| Compound Name |
9-(3-Hydroxypropyl)-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
711-64-8; 9H-Purine-9-propanol, 6-amino-; CHEMBL445974; 9-(3-Hydroxypropyl)-9H-adenine; 3-(6-Amino-9H-purin-9-yl)propan-1-ol; 9-(3-Hydroxypropyl)adenine; Oprea1_108729; 9-(3'-hydroxypropyl)adenine; SCHEMBL1635576; CTK2H3970; DTXSID10500041; MolPort-014-160-140; ZINC5391161; BDBM50257052; 3-(6-aminopurin-9-yl)propan-1-ol; AKOS010941287; 3-(6-Amino-9H-purine-9-yl)-1-propanol
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| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
9-Isopropyl-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL67199; 9-isopropyl-9H-purin-6-amine; 31601-35-1; 9-Isopropyl-9H-adenine; 9-propan-2-ylpurin-6-amine; SCHEMBL754007; AC1L987T; 6-Amino-9-isopropyl-9H-purine; 9-Isopropyl-9H-purin-6-ylamine; BDBM50013685; AKOS022639673; 9H-Purin-6-amine, 9-(1-methylethyl)-
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| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
9-Phenylethyl-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
9-Phenethyladenine; CHEMBL445696; 7051-86-7; 9-Phenylethyl-9H-adenine; NSC211638; AC1L7EWL; Maybridge3_003004; 9-phenethylpurin-6-amine; 9-(2-phenylethyl)adenine; MLS001181918; SCHEMBL1230786; 6-Amino-9-phenethyl-9H-purine; DTXSID10309298; MolPort-002-902-800; ZINC158322; HMS1439I12; HMS2852H03; BDBM50257097; CCG-51741; AKOS012923591; NSC-211638; MCULE-7488166280; IDI1_014391; SMR000567667
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| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
9-But-3-enyl-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL510907; 9-But-3-enyl-9H-adenine; BDBM50256954
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| Activity |
Ki ~ 100000 nM
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[6] | |||
| Compound Name |
8-Bromo-9-(2,3-dihydroxypropyl)-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL505633; 3-(6-amino-8-bromopurin-9-yl)propane-1,2-diol; 3-(6-Amino-8-bromo-purin-9-yl)-propane-1,2-diol; AC1MCMJY; 8-Bromo-9-(2,3-dihydroxypropyl)-9H-adenine; C8H10BrN5O2; Oprea1_182885; Oprea1_060925; MolPort-000-712-951; 3-(6-AMINO-8-BROMO-9H-PURIN-9-YL)PROPANE-1,2-DIOL; STL558390; CCG-18677; BDBM50257096; AKOS001644314; MCULE-9507586118; BAS 00110783; 69369-04-6; ST50975882
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| Activity |
Ki ~ 100000 nM
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[6] | |||
| Compound Name |
9-(2-Hydroxyethyl)-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
2-(6-aminopurin-9-yl)ethanol; 707-99-3; 9-(2-Hydroxyethyl)adenine; 9h-purine-9-ethanol, 6-amino-; 9-(2-hydroxyethyl) adenine; CHEMBL95897; 6-Amino-9H-purin-9-ethanol; VAQOTZQDXZDBJK-UHFFFAOYSA-N; 6-Amino-9-(2-hydroxyethyl)purine; 2-(6-Amino-9H-purin-9-yl)ethanol; 9-(2-Hydroxyethyl)-9H-adenine; NSC51467; N9 -hydroxyethyladenine; AC1Q4VHV; 9-(2hydroxyethyl)adenine; ACMC-209og5; TimTec1_003634; 9-(2'-hydroxyethyl)adenine; 9-(2-Hydroxyethyl)adenine.; SCHEMBL984944; 6-Amino-9h-purine-9-ethanol; AC1L69W8; ZINC36416; KS-00000VZR
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| Activity |
Ki ~ 100000 nM
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[6] | |||
| Compound Name |
9-Cyclopropyl-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL469409; 9-Cyclopropyl-9H-adenine; 9-cyclopropylpurin-6-amine; AC1L987W
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| Activity |
Ki ~ 100000 nM
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[6] | |||
| Compound Name |
2-(6-amino-8-bromo-9H-purin-9-yl)ethanol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL474058; 43047-77-4; 8-Bromo-9-(2-hydroxyethyl)-9H-adenine; 2-(6-amino-8-bromo-9H-purin-9-yl)ethanol; SCHEMBL987368; CTK1C8207; DTXSID50659527; HPCQLQBYCLLETI-UHFFFAOYSA-N; BDBM50257051; AKOS030562477; 9H-Purine-9-ethanol, 6-amino-8-bromo-; 2-(6-amino-8-bromo-purin-9-yl)ethanol; 6-amino-8-bromo-9-(2-hydroxyethyl)-9H-purine
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| Activity |
Ki ~ 100000 nM
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[7] | |||
| Compound Name |
9-(2-Hydroxypropyl)-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
9-(2-Hydroxypropyl)adenine; 1-(6-aminopurin-9-yl)propan-2-ol; CHEMBL504495; MJZYTEBKXLVLMY-UHFFFAOYSA-N; 9-(2-Hydroxypropyl)-9H-adenine; AC1L1CKL; 9H-Purine-9-ethanol, 6-amino-.alpha.-methyl-; SCHEMBL904363; CTK6A8458; 9-(2-Hydroxy-1-propyl)adenine; BCP14341; BDBM50257055; 3-(6-Amino-9-purinyl)-2-propanol; AKOS010941288; TRA0093894; AN-7936; 1-(6-Amino-purin-9-yl)-propan-2-ol; SY022843; A3032; 4CH-024207; 4CH-018216; 1-(6-Amino-9H-purin-9-yl)-2-propanol #; MFCD07369451 (97+%)
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| Activity |
Ki ~ 100000 nM
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[6] | |||
| Compound Name |
8-Bromo-9-methyl-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
8-Bromo-9-methyl-9H-adenine; 8-bromo-9-methyladenine; CHEMBL510288; 56489-40-8; AC1LGJ6D; Oprea1_555380; SCHEMBL8832637; 8-bromo-9-methylpurin-6-amine; CTK1E1875; DTXSID90356366; ICJDGKILGBQWGF-UHFFFAOYSA-N; BDBM50256842; AKOS022687396; 6-Amino-8-bromo-9-methyl-9H-purine; 9H-Purin-6-amine, 8-bromo-9-methyl-
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| Activity |
Ki ~ 100000 nM
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[7] | |||
| Compound Name |
9-BENZYL-9H-ADENINE
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Investigative | Compound Info | ||
| Synonyms |
9-Benzyladenine; 4261-14-7; 9-benzyl-9H-purin-6-amine; N9-Benzyladenine; 9-Benzylaminopurine; ADENINE, 9-BENZYL-; 9-Bap; 9-Benzyl-6-aminopurine; N(sup 9)-Benzyladenine; 9-BENZYL-9H-ADENINE; 9-Benzyl-9H-purin-6-ylamine; 9H-Purin-6-amine, 9-(phenylmethyl)-; CCRIS 6908; SQ 21611; 9-benzylpurin-6-amine; NSC 35649; 9-(Phenylmethyl)-9H-purin-6-amine; CHEMBL266094; 9H-Purin-6-amine,9-(phenylmethyl)-; AC1L2FWA; MLS000660735; SCHEMBL104932; 9-Benzyl-9H-purine-6-amine; CTK4I6467; DTXSID70195371; MRHCSNNEUHXNIC-UHFFFAOYSA-N; HMS2676M21
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| Activity |
Ki ~ 100000 nM
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[6] | |||
| Compound Name |
8-Bromo-9-(2-butyl)-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL505089; 202136-43-4; (8-bromo-9-butyl-9H-purin-6-yl)amine; 8-Bromo-9-(2-butyl)-9H-adenine; 8-bromo-9-butyladenine; SCHEMBL1965296; CTK4E3576; DTXSID80469393; FKNNQOCJLMQVAV-UHFFFAOYSA-N; BDBM50256953; AKOS015965383; 9H-Purin-6-amine,8-bromo-9-butyl-
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| Activity |
Ki ~ 100000 nM
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[6] | |||
| Compound Name |
9-Cycloheptyl-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
9-cycloheptylpurin-6-amine; 9-cycloheptyl-9h-purin-6-amine; CHEMBL62835; 6961-60-0; 9-Cycloheptyl-9H-adenine; NSC62733; AC1L6KRZ; AC1Q4VH9; CTK5D0614; DTXSID20289678; 6-Amino-9-cycloheptyl-9H-purine; 9-Cycloheptyl-9H-purin-6-ylamine; 9H-Purin-6-amine, 9-cycloheptyl-; BDBM50013702; NSC-62733
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| Activity |
Ki ~ 100000 nM
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[6] | |||
| Compound Name |
8-Bromo-9-(2-hydroxypropyl)-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
8-Bromo-9-(2-hydroxypropyl)-9H-adenine; CHEMBL475617; 98411-78-0
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| Activity |
Ki ~ 100000 nM
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[6] | |||
| Compound Name |
8-Bromo-9-(but-3-enyl)-9H-adenine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL508561; 8-Bromo-9-(but-3-enyl)-9H-adenine
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| Activity |
Ki ~ 100000 nM
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[6] | |||
| Compound Name |
7-Isopropyl-7H-adenine
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Investigative | Compound Info | ||
| Synonyms |
7-Isopropyl-7H-adenine; CHEMBL448396; 55146-09-3; SCHEMBL756635
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| Activity |
Ki ~ 100000 nM
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[6] | |||
| Compound Name |
3-Hydroxy-2-(2,4,6-trimethoxyphenyl)chromen-4-one
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Investigative | Compound Info | ||
| Synonyms |
NSC78634; CHEMBL76933; MLS002701916; 3-Hydroxy-2-(2,4,6-trimethoxyphenyl)-4H-chromen-4-one; CTK6J9289; ZINC1718914; BDBM50051339; 2',4',6'-Trimethoxy-3-hydroxyflavone; NCI60_041736; SMR001565500; 4H-1-Benzopyran-4-one,4,6-trimethoxyphenyl)-; 3-Hydroxy-2-(2,4,6-trimethoxy-phenyl)-chromen-4-one; 4H-1-Benzopyran-4-one, 3-hydroxy- 2-(2,4,6-trimethoxyphenyl)-
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| Activity |
Ki = 50100 nM
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[2] | |||
| Compound Name |
1-(3-Chlorophenyl)-3-[4-(furan-2-yl)-11-(2-naphthalen-1-ylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL145123; BDBM50094698
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| Activity |
Ki = 51286.14 nM
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[5] | |||
| Compound Name |
1-(3-Chlorophenyl)-3-[4-(furan-2-yl)-11-(3-methylbut-2-enyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL342500; BDBM50094685
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| Activity |
Ki = 54954.09 nM
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[5] | |||
| Compound Name |
1-[4-(Furan-2-yl)-11-(3-phenylpropyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-propan-2-ylurea
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL366864; BDBM50158778
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| Activity |
Ki = 54954.09 nM
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[5] | |||
| Compound Name |
5-(Cyclohexylcarbamoylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3314886; BDBM50047989
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| Activity |
Ki = 59400 nM
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[8] | |||
| Compound Name |
4-Chloro-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidin-6-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3114141; BDBM50495621
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| Activity |
Ki ~ 60000 nM
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[9] | |||
| Compound Name |
N-(4-Chloro-2-propan-2-ylpyrazolo[3,4-d]pyrimidin-6-yl)-4-fluorobenzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3114148; BDBM50495610
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| Activity |
Ki ~ 60000 nM
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[9] | |||
| Compound Name |
(2S,3S,4R,5R)-5-[6-Amino-2-[2-[4-[(3,5-ditert-butylbenzoyl)amino]phenyl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2042301; BDBM50385945
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| Activity |
IC50 = 60097 nM
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[10] | |||
| Compound Name |
1-(3-Chlorophenyl)-3-[4-(furan-2-yl)-11-(3-phenylpropyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL342906; SCHEMBL1389176; BDBM50082420
Click to Show/Hide
|
||||
| Activity |
Ki = 60255.96 nM
|
[5] | |||
| Compound Name |
(1S,2S,3R,4R,5S)-1-(6-Aminopurin-9-yl)-4-(hydroxymethyl)bicyclo[3.1.0]hexane-2,3-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2112095
Click to Show/Hide
|
||||
| Activity |
Ki = 62500 nM
|
[11] | |||
| Compound Name |
1-Tert-butyl-3-[4-(furan-2-yl)-11-(3-phenylpropyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL177524; BDBM50158788
Click to Show/Hide
|
||||
| Activity |
Ki = 64565.42 nM
|
[5] | |||
| Compound Name |
1-[4-(Furan-2-yl)-11-(3-methylbutyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-propan-2-ylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL179638; BDBM50158775
Click to Show/Hide
|
||||
| Activity |
Ki = 64565.42 nM
|
[5] | |||
| Compound Name |
3,4-Dimethyl-N-(3-(pyridin-2-yl)isoquinolin-1-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL127383; BDBM50067097; 3,4-Dimethyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide; N-[3-(2-Pyridinyl)isoquinoline-1-yl]-3,4-dimethylbenzamide
Click to Show/Hide
|
||||
| Activity |
Ki = 69000 nM
|
[12] | |||
| Compound Name |
1-(3-Chlorophenyl)-3-[4-(furan-2-yl)-11-[2-(2,4,5-tribromophenyl)ethyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL341852; BDBM50094681
Click to Show/Hide
|
||||
| Activity |
Ki = 70794.58 nM
|
[5] | |||
| Compound Name |
3-Amino-N-[4-(furan-2-yl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]propanamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL366737
Click to Show/Hide
|
||||
| Activity |
Ki = 79983.43 nM
|
[5] | |||
| Compound Name |
1-Phenyl-3-(2-(pyrrolidin-1-yl)quinazolin-4-yl)urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL71726; BDBM50088473; 1-(2-Pyrrolizino-4-quinazolinyl)-3-phenylurea; 1-Phenyl-3-(2-pyrrolidin-1-yl-quinazolin-4-yl)-urea
Click to Show/Hide
|
||||
| Activity |
Ki = 82300 nM
|
[13] | |||
| Compound Name |
1-(2-Methoxy-phenyl)-3-(2-phenyl-quinazolin-4-yl)-urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
VUF-5386; CHEMBL308087; BDBM50088471
Click to Show/Hide
|
||||
| Activity |
Ki = 87300 nM
|
[13] | |||
| Compound Name |
4-Methoxy-5-oxo-5H-furo[3,2-g]chromene-7-carbaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL75514; SCHEMBL1663878; BDBM50051341; ZINC13776565
Click to Show/Hide
|
||||
| Activity |
Ki = 88900 nM
|
[2] | |||
| Compound Name |
4-Methyl-N-(3-(pyridin-2-yl)isoquinolin-1-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL339261; Benzamide, 4-methyl-N-[3-(2-pyridinyl)-1-isoquinolinyl]-; ACMC-20mgjx; SCHEMBL936187; 4-methyl-N-(3-pyridin-2-ylisoquinolin-1-yl)benzamide; CTK0G1474; DTXSID40438727; VUF-8502; BDBM50067111; 4-Methyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide; 4-methyl-N-[3-(2-pyridinyl)-1-isoquinolinyl]benzamide
Click to Show/Hide
|
||||
| Activity |
Ki = 96000 nM
|
[12] | |||
| Compound Name |
N-(4-Chloro-2-propan-2-ylpyrazolo[3,4-d]pyrimidin-6-yl)-4-methylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3114150; BDBM50495615
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[9] | |||
| Compound Name |
7-(2-Hydroxypropyl)-7H-adenine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL475456; 1-(6-aminopurin-7-yl)propan-2-ol; BDBM50257056
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
Ethyl 6-(dibenzoylamino)-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410317; BDBM50072929
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[14] | |||
| Compound Name |
2-Chloro-N6-cyclopentyl-9H-(2-C-methyl-5-Nmethylcarbamoyl-beta-D-ribofuranosyl)adenine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254064; BDBM50224760
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[15] | |||
| Compound Name |
Ethyl 6-[bis(3,4-difluorobenzoyl)amino]-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410319; BDBM50072927
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[14] | |||
| Compound Name |
(1S,3R,4R,7S)-1-(Hydroxymethyl)-3-[6-[(3-iodophenyl)methylamino]purin-9-yl]-2,5-dioxabicyclo[2.2.1]heptan-7-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL235317; SCHEMBL3231369; BDBM50215118
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
(1R,3R,4R,7S)-1-(Hydroxymethyl)-3-[6-[(3-iodophenyl)methylamino]purin-9-yl]-2-oxa-5-azabicyclo[2.2.1]heptan-7-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL235543; SPN-0234; BDBM50215111
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
6-Amino-2-propan-2-ylpyrazolo[3,4-d]pyrimidine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410295; BDBM50072919
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[14] | |||
| Compound Name |
2'-O-Methyladenosine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Adenosine, 2'-O-methyl-; cordysinin B; 2'-O-Methyl adenosine; UNII-02YX82IHZ5; CHEMBL73237; 2'-O-METHYL-ADENOSINE; 02YX82IHZ5; (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol; MFCD00056002; 2`-O-Methyladenosine; 2''-O-Methyladenosine; 2'-O-Me-Ado; SCHEMBL25936; 2'-O-Me-A; CTK1A7124; DTXSID50175671; BCP17411; ZINC3776540; 0883AB; ANW-64052; BDBM50144945; HG1274; PDSP1_001054; PDSP2_001038; AKOS016003815; AC-8216; CS-W012268; HY-W011552; DS-14586; SC-43502; K-6125; 140M796; Q63392855; 5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
(1R,3R,4R,7S)-3-(6-Amino-purin-9-yl)-1-hydroxymethyl-2-oxa-5-aza-bicyclo[2.2.1]heptan-7-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL235542; BDBM50215112
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-Chloro-N6-cyclopentyl-9H-(2-C-methyl-5-N-methylthiocarbamoyl-beta-D-ribofuranosyl)adenine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399514; BDBM50224769
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[15] | |||
| Compound Name |
Ethyl 6-(dibenzoylamino)-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410321; BDBM50072925
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[14] | |||
| Compound Name |
6-Amino-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410294; BDBM50072920
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[14] | |||
| Compound Name |
[(2R,3R,4R,5R)-5-[2-Chloro-6-[[(3R)-oxolan-3-yl]amino]purin-9-yl]-3,4-dihydroxy-4-methyloxolan-2-yl]methyl N-methylcarbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254693; BDBM50224773; 2-chloro-N6-(R)-3-tetrahydrofuranyl-9H-(2-C-methyl-5-N-methylcarbamoyl-beta-D-ribofuranosyl)adenine
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[15] | |||
| Compound Name |
8-Bromo-9-cycloheptyl-9H-adenine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL474396; BDBM50257003
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
N6-(3-Iodobenzyl)-9-(3-deoxy-3-ureido-B-D-ribofuranosyl)adenine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL382194; MRS-3481; BDBM50185932
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[17] | |||
| Compound Name |
(1S,3R,4R,7S)-7-Hydroxy-3-[6-[(3-iodophenyl)methylamino]purin-9-yl]-N-methyl-2-oxa-5-azabicyclo[2.2.1]heptane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL391483; BDBM50215110
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
7-Methyladenine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
7-Methyl-7H-purin-6-amine; 6-Amino-7-methylpurine; N7-Methyladenine; 7H-Purin-6-amine, 7-methyl-; Adenine, 7-methyl-; 7-methylpurin-6-amine; 7H-Purin-6-amine, 7-methyl- (9CI); CHEMBL449346; MFCD00127790; NSC 7857; 7-Methyl-7H-adenine; 7-methyl-6-purinamine; 7-Methyladenine, 97%; 7-methylpurine-6-ylamine; 7-methyl-N7-Methyladenine; DSSTox_CID_29335; DSSTox_RID_83451; DSSTox_GSID_49376; SCHEMBL26976; Adenine, 7-methyl- (8CI); 7-Methyl-7H-purin-6-ylamine; DTXSID9049376; 7-Methyl-7H-purin-6-amine #; CTK5H2669; NSC7857; ZINC901320; KS-000018VI; NSC-7857; Tox21_202951; 5887AC; BDBM50240579; AKOS000320617; AKOS006378195; NCGC00260497-01; SY250877; TS-00058; N-ACETYL-DL-2-AMINO-N-BUTYRICACID; FT-0657514; ST50298865; 7-methyl-7H-purin-6-amine (ACD/Name 4.0); C02241; 7-methyl-7H-purin-6-ylamine (ACD/Name 4.0); 935M693; A844638; J-640190; J-800191; W-204088; 6-Amino-7-methylpurine, 7-Methyl-7H-purin-6-amine; Q27103966
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
N-(4-Chlorophenyl)-7-morpholin-4-yl-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3088347; BDBM50189095
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[18] | |||
| Compound Name |
(1S,3R,4R,7S)-3-(6-Aminopurin-9-yl)-7-hydroxy-N-methyl-2-oxa-5-azabicyclo[2.2.1]heptane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL391279; BDBM50215109; (1R,3R,4R,7S)-(7-hydroxy-3-(adenin-9-yl)-2-oxa-5-azabicyclo[2:2:1]hept-1-yl)-N-methylcarboxamide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Ethyl 2-propan-2-yl-6-[[4-(trifluoromethyl)benzoyl]amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410308; BDBM50072941
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[14] | |||
| Compound Name |
N-[4-Chloro-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-6-yl]-4-fluorobenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3114156; BDBM50495611
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[9] | |||
| Compound Name |
Ethyl 6-[(4-fluorobenzoyl)amino]-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410303; BDBM50072936
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[14] | |||
| Compound Name |
4-Chloro-2-methylpyrazolo[3,4-d]pyrimidin-6-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3114139; BDBM50495603
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[9] | |||
| Compound Name |
1-Ethoxymethyl-2-methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90733; SCHEMBL1663983; BDBM50059388
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[19] | |||
| Compound Name |
9H-Purin-6-amine, 9-(2-methylpropyl)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL503566; 9-Isobutyladenine; 9-Isobutyl-9H-adenine; SCHEMBL12620928; BDBM50256948; AKOS012922846
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
7-Isobutyl-7H-adenine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL472147; BDBM50256949
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
9-Cyclohexyladenine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
9-cyclohexylpurin-6-amine; 9-Cyclohexyl-9H-purin-6-amine; 9H-Purin-6-amine, 9-cyclohexyl-; CHEMBL63783; NSC 19201; BRN 0220522; SQ 22244; N9-Cyclohexyladenine; 9-Cyclohexyl-9H-adenine; 6-Amino-9-cyclohexylpurine; Purine, 6-amino-9-cyclohexyl; SCHEMBL3245641; ZINC12513; 6-Amino-9-cyclohexyl-9H-purine; DTXSID20195164; 9-Cyclohexyl-9H-purin-6-ylamine; NSC19201; BDBM50013711; NSC-19201; DS-006123; WLN: T56 BN DN FN HNJ D- AL6TJ& IZ
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
2,5,7,9-Tetramethylpyrido[3,4-b]indol-2-ium-6-ol;iodide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL540656
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[20] | |||
| Compound Name |
7-Ethylpurin-6-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
7-ethyl-7h-purin-6-amine; CHEMBL451363; 7-Ethyl Adenine; 7H-Purin-6-amine,7-ethyl-; 7-ethyladenine; 7H-Purin-6-amine, 7-ethyl-; 7-Ethyl-7H-adenine; 6-Amino-7-ethyl-7H-purine; SCHEMBL5801729; CTK4F3335; DTXSID00947143; BDBM50256843
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
O-[[(2R,3R,4R,5R)-5-[2-Chloro-6-[[(3R)-oxolan-3-yl]amino]purin-9-yl]-3,4-dihydroxy-4-methyloxolan-2-yl]methyl] N-methylcarbamothioate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254896; BDBM50224763
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[15] | |||
| Compound Name |
7-(Sec-Butyl)-7H-adenine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL475030; BDBM50256897
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
Ethyl 6-benzamido-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410302; BDBM50072935
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[14] | |||
| Compound Name |
LNA-Adenosine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL393578; 2'-O,4'-C-Methyleneadenosine; SCHEMBL858866; adenosine, 2'-O,4'-methylene-; BDBM50215117
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
7-(2,3-Dihydroxypropyl)-7H-adenine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL474623; BDBM50257095
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
N-[(4-Fluorophenyl)methyl]-2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3753103; BDBM50137533
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[21] | |||
| Compound Name |
5'-N-[(2-Amino)ethyl Carboxamido] Adenosine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL129903; Adenosine analog, 1; BDBM50106539; 5'-Deoxy-5'-(2-aminoethyl)amino-5'-oxoadenosine; 5''-N-[(2-AMINO)ETHYL CARBOXAMIDO] ADENOSINE; Q27463678
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[17] | |||
| Compound Name |
4-Chloro-2-propan-2-ylpyrazolo[3,4-d]pyrimidin-6-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3114140; BDBM50495617
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[9] | |||
| Compound Name |
N-Phenyl-7-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3088346; BDBM50189094
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[18] | |||
| Compound Name |
4-Chloro-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-6-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3114142; BDBM50495608
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[9] | |||
| Compound Name |
(1S,3R,4R,7S)-3-(6-Aminopurin-9-yl)-7-hydroxy-N-methyl-2,5-dioxabicyclo[2.2.1]heptane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL410746; BDBM50215114; (1R,3R,4R,7S)-(7-hydroxy-3-(adenin-9-yl)-2,5-dioxabicyclo[2:2:1]hept-1-yl)-N-methylcarboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
(1S,3R,4R,7S)-7-Hydroxy-3-[6-[(3-iodophenyl)methylamino]purin-9-yl]-N-methyl-2,5-dioxabicyclo[2.2.1]heptane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL391278; BDBM50215113
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
7-(3-Hydroxypropyl)-7H-adenine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL447623; BDBM50257053
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
7-Chloro-N-(2-morpholin-4-ylethyl)-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3828675; BDBM50189176
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[18] | |||
| Compound Name |
7-(2-Hydroxyethyl)adenine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(6-aminopurin-7-yl)ethanol; 7-(2-Hydroxyethyl)-7H-adenine; CHEMBL466850; SCHEMBL4815870; DTXSID60452081; BDBM50257050; ZINC40913978; 2-(6-Amino-7H-purin-7-yl)ethanol; FT-0669615
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[6] | |||
| Compound Name |
Ethyl 2-methyl-6-[[4-(trifluoromethyl)benzoyl]amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410304; BDBM50072937
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[14] | |||
| Compound Name |
Ethyl 2-methyl-6-[(4-methylbenzoyl)amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410305; BDBM50072938
Click to Show/Hide
|
||||
| Activity |
Ki = 100000 nM
|
[14] | |||
| Compound Name |
1-(2-Phenyl-quinazolin-4-yl)-3-o-tolyl-urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL71756; BDBM50088477; 1-(2-Phenyl-4-quinazolinyl)-3-(2-methylphenyl)urea
Click to Show/Hide
|
||||
| Activity |
Ki = 115000 nM
|
[13] | |||
| Compound Name |
3-Benzylsulfanyl-4-oxo-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL336968; BDBM50048453
Click to Show/Hide
|
||||
| Activity |
Ki = 117000 nM
|
[22] | |||
| Compound Name |
1-(4-Methoxy-phenyl)-3-(4-pyridin-2-yl-thiazol-2-yl)-urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL162271; BDBM50097437
Click to Show/Hide
|
||||
| Activity |
Ki = 147000 nM
|
[23] | |||
| Compound Name |
3-Methoxy-N-(3-(pyridin-2-yl)isoquinolin-1-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL130888; BDBM50067099; 3-Methoxy-N-[3-(2-pyridinyl)-1-isoquinolinyl]benzamide; 3-Methoxy-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide
Click to Show/Hide
|
||||
| Activity |
Ki = 150000 nM
|
[12] | |||
| Compound Name |
2-Amino-N-[4-(furan-2-yl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]acetamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL176010
Click to Show/Hide
|
||||
| Activity |
Ki = 162929.6 nM
|
[5] | |||
| Compound Name |
1-Methoxymethyl-2-methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-(2-trimethylsilanyl-ethyl) ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL89391; SCHEMBL1663975; BDBM50059408
Click to Show/Hide
|
||||
| Activity |
Ki = 170000 nM
|
[19] | |||
| Compound Name |
4-Chloro-N-(3-(pyridin-2-yl)isoquinolin-1-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL440339; BDBM50067114; 4-Chloro-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide; 4-Chloro-N-[3-(2-pyridinyl)-1-isoquinolinyl]benzamide
Click to Show/Hide
|
||||
| Activity |
Ki = 200000 nM
|
[12] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 65 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
3,4-Dichloro-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL131532; BDBM50067113; 3,4-Dichloro-N-[3-(2-pyridinyl)-1-isoquinolinyl]benzamide
Click to Show/Hide
|
||||
| Activity |
Ki = 210000 nM
|
[12] | |||
| Compound Name |
1-(2-Phenyl-4-quinazolinyl)-3-(2-chlorophenyl)urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL70955; BDBM50088460; 1-(2-Chloro-phenyl)-3-(2-phenyl-quinazolin-4-yl)-urea
Click to Show/Hide
|
||||
| Activity |
Ki = 220000 nM
|
[13] | |||
| Compound Name |
N-(2-Pyridin-2-yl-quinazolin-4-yl)-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL424259; SCHEMBL10708288; BDBM50067107; N-(2-pyridin-2-ylquinazolin-4-yl)benzamide; N-[2-(2-Pyridyl)-4-quinazolinyl]benzamide
Click to Show/Hide
|
||||
| Activity |
Ki = 230000 nM
|
[12] | |||
| Compound Name |
N-Benzoyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL128396; BDBM50067084; N-[3-(2-Pyridinyl)-1-isoquinolinyl]-N-benzoylbenzamide
Click to Show/Hide
|
||||
| Activity |
Ki = 230000 nM
|
[12] | |||
| Compound Name |
3-Methyl-N-(3-(pyridin-2-yl)isoquinolin-1-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL424071; BDBM50067095; 3-Methyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide; 3-Methyl-N-[3-(2-pyridinyl)-1-isoquinolinyl]benzamide
Click to Show/Hide
|
||||
| Activity |
Ki = 240000 nM
|
[12] | |||
| Compound Name |
1-[2-(2-Furyl)-4-quinazolinyl]-3-phenylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL69841; BDBM50088468; 1-(2-Furan-2-yl-quinazolin-4-yl)-3-phenyl-urea
Click to Show/Hide
|
||||
| Activity |
Ki = 257000 nM
|
[13] | |||
| Compound Name |
1-[2-(6-Methyl-2-pyridyl)-4-quinazolinyl]-3-phenylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL70948; BDBM50088474; 1-[2-(6-Methyl-pyridin-2-yl)-quinazolin-4-yl]-3-phenyl-urea
Click to Show/Hide
|
||||
| Activity |
Ki = 264000 nM
|
[13] | |||
| Compound Name |
4-(Furan-2-yl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL16867; SCHEMBL4759270; BDBM50051234; 2-(2-Furyl)-7-phenethyl-7H-1,3,3a,5,6,7-hexaaza-as-indacene-4-amine; 2-(furan-2-yl)-8-phenethyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Click to Show/Hide
|
||||
| Activity |
Ki = 281838.29 nM
|
[5] | |||
| Compound Name |
1-(2-Phenyl-4-quinazolinyl)-3-phenylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL310534; SCHEMBL1083798; BDBM50088467; 1-Phenyl-3-(2-phenyl-quinazolin-4-yl)-urea
Click to Show/Hide
|
||||
| Activity |
Ki = 287000 nM
|
[13] | |||
| Compound Name |
5-Amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e] 1,2,4-triazolo[1,5-c]pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL342059; SCHEMBL4758522; BDBM50094701; 7-Methyl-2-(2-furyl)-7H-1,3,3a,5,6,7-hexaaza-as-indacene-4-amine; 2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine; 2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine; 5-amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Click to Show/Hide
|
||||
| Activity |
Ki = 301995.17 nM
|
[5] | |||
| Compound Name |
[(4-Methoxyphenyl)iminomethyl](3-(2-pyridyl)isoquinolyl)amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL339967; VUF8505; VUF-8505; BDBM50067080; 4-methoxy-N-[3-(2-pyridyl)-1-isoquinolyl]benzamidine; 4-Methoxy-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 310000 nM
|
[24] | |||
| Compound Name |
3,4-Dimethoxy-N-(3-(pyridin-2-yl)isoquinolin-1-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL130130; BDBM50067098; 3,4-Dimethoxy-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide; N-[3-(2-Pyridinyl)isoquinoline-1-yl]-3,4-dimethoxybenzamide
Click to Show/Hide
|
||||
| Activity |
Ki = 310000 nM
|
[12] | |||
| Compound Name |
3,5-Dimethyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL340615; BDBM50067101
Click to Show/Hide
|
||||
| Activity |
Ki = 320000 nM
|
[12] | |||
| Compound Name |
4-(Furan-2-yl)-11-propyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL344706; SCHEMBL4759841; BDBM50082416; 7-Propyl-2-(2-furyl)-7H-1,3,3a,5,6,7-hexaaza-as-indacene-4-amine; 2-(furan-2-yl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine; 2-Furan-2-yl-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine; amino-8-propyl-2-(2-furyl) pyrazolo (4,3-e)-1,2,4-triazolo (1,5-c)pyrimidine
Click to Show/Hide
|
||||
| Activity |
Ki = 331131.12 nM
|
[5] | |||
| Compound Name |
1-[2-(4-Pyridyl)-4-quinazolinyl]-3-phenylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL72183; BDBM50088470; 1-Phenyl-3-(2-pyridin-4-yl-quinazolin-4-yl)-urea
Click to Show/Hide
|
||||
| Activity |
Ki = 336000 nM
|
[13] | |||
| Compound Name |
2-Furan-2-yl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL276738; 2-(Furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine; C10H7N7O; SCHEMBL2307829; SCHEMBL2307837; SCHEMBL8281893; 1727AJ; BDBM50051230; MFCD18914402; ZINC13835600; 5-Amino-2-(2-furyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine; SB34079; 7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-; SY164414; Z-6790; 2-(2-Furyl)-6H-1,3,3a,5,6,7-hexaaza-as-indacene-4-amine; 2-(2-Furanyl)-7H-1,3,3a,5,6,7-hexaaza-as-indacene-4-amine; 2-Furan-2-yl-7H-pyrazolo[4,3-e[1,2,4triazolo[1,5-cpyrimidin-5-ylamine; 2-Furan-2-yl-7H-pyrazolo4,3-e1,2,4triazolo1,5-cpyrimidin-5-ylamine; 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine; 2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine; 2-Furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Click to Show/Hide
|
||||
| Activity |
Ki = 346736.85 nM
|
[5] | |||
| Compound Name |
2,4-Dimethyl-N-(3-(pyridin-2-yl)isoquinolin-1-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL128886; BDBM50067105; 2,4-Dimethyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide
Click to Show/Hide
|
||||
| Activity |
Ki = 360000 nM
|
[12] | |||
| Compound Name |
1-Phenyl-2-(3-pyridin-2-yl-isoquinolin-1-yl)-propan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL334876; BDBM50067075; alpha-[3-(2-Pyridinyl)isoquinolin-1-yl]propiophenone
Click to Show/Hide
|
||||
| Activity |
Ki = 370000 nM
|
[24] | |||
| Compound Name |
5-Amino-8-ethyl-2-(2-furyl)-pyrazolo[4,3-e] 1,2,4-triazolo[1,5-c]pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL137879; SCHEMBL4759566; BDBM50082417; 7-Ethyl-2-(2-furyl)-7H-1,3,3a,5,6,7-hexaaza-as-indacene-4-amine; 5-amino-8-ethyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine; 8-ethyl-2-(2-furyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine; 8-ethyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine; 8-Ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Click to Show/Hide
|
||||
| Activity |
Ki = 407380.28 nM
|
[5] | |||
| Compound Name |
4-(Furan-2-yl)-11-(3-phenylpropyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL423542; SCHEMBL4824435; BDBM50082423; 2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine; 2-Furan-2-yl-8-(3-phenyl-propyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Click to Show/Hide
|
||||
| Activity |
Ki = 426579.52 nM
|
[5] | |||
| Compound Name |
2,5-Dimethyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL128715; BDBM50067103
Click to Show/Hide
|
||||
| Activity |
Ki = 430000 nM
|
[12] | |||
| Compound Name |
N-Benzoyl-N-(2-pyridin-2-yl-quinazolin-4-yl)-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL130054; BDBM50067100; N-[2-(2-Pyridinyl)quinazoline-4-yl]-N-benzoylbenzamide
Click to Show/Hide
|
||||
| Activity |
Ki = 470000 nM
|
[12] | |||
| Compound Name |
4-Methyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL128152; Benzenecarboximidamide, 4-methyl-N-[3-(2-pyridinyl)-1-isoquinolinyl]-; ACMC-20mnmm; CTK0F9980; DTXSID50434699; VUF-8503; BDBM50067092; 4-Methyl-N-(3-(pyridin-2-yl)isoquinolin-1-yl)benzimidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 580000 nM
|
[24] | |||
| Compound Name |
11-Butyl-4-(furan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL16894; SCHEMBL4758498; BDBM50051242; 2-(2-Furyl)-7-butyl-7H-1,3,3a,5,6,7-hexaaza-as-indacene-4-amine; 8-butyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine; 8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Click to Show/Hide
|
||||
| Activity |
Ki = 602559.59 nM
|
[5] | |||
| Compound Name |
alpha-[3-(2-Pyridinyl)-1-isoquinolinyl]acetophenone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL72287; BDBM50067079; 1-Phenyl-2-(3-pyridin-2-yl-isoquinolin-1-yl)-ethanone
Click to Show/Hide
|
||||
| Activity |
Ki = 660000 nM
|
[12] | |||
| Compound Name |
4-(Furan-2-yl)-11-(3-methylbutyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL315150; SCHEMBL4758537; BDBM50094688; 2-(2-Furyl)-7-isopentyl-7H-1,3,3a,5,6,7-hexaaza-as-indacene-4-amine; 2-(furan-2-yl)-8-isopentyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine; 2-Furan-2-yl-8-(3-methyl-butyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Click to Show/Hide
|
||||
| Activity |
Ki = 707945.78 nM
|
[5] | |||
| Compound Name |
N'-(3-Pyridin-2-ylisoquinolin-1-yl)benzenecarboximidamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL72897; VUF8501; SCHEMBL10711811; VUF-8501; BDBM50067089; N-[3-(2-pyridyl)-1-isoquinolyl]benzamidine; N-(3-Pyridin-2-yl-isoquinolin-1-yl)-benzamidine; (Iminophenylmethyl)(3-(2-pyridyl)isoquinolyl)amine
Click to Show/Hide
|
||||
| Activity |
Ki = 740000 nM
|
[12] | |||
| Compound Name |
3-Chloro-N-(3-(pyridin-2-yl)isoquinolin-1-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
TCMDC-123886; CHEMBL128538; DNDI1417645; VUF-8512; BDBM50067102; 3-Chloro-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide
Click to Show/Hide
|
||||
| Activity |
Ki = 770000 nM
|
[12] | |||
| Compound Name |
6,7-Dimethoxy-4H-indeno[1,2-d][1,3]thiazol-2-amine;hydroiodide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43299; SCHEMBL3990222; BDBM50451379
Click to Show/Hide
|
||||
| Activity |
EC50 = 794328.23 nM
|
[25] | |||
| Compound Name |
4-(Furan-2-yl)-11-(3-methylbut-2-enyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL145623; BDBM50094682; 7-(3-Methyl-2-butenyl)-2-(2-furanyl)-7H-1,3,3a,5,6,7-hexaaza-as-indacene-4-amine; 2-(furan-2-yl)-8-(3-methylbut-2-enyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine; 2-Furan-2-yl-8-(3-methyl-but-2-enyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Click to Show/Hide
|
||||
| Activity |
Ki = 812830.52 nM
|
[5] | |||
| Compound Name |
[(3-Methoxyphenyl)iminomethyl](3-(2-pyridyl)isoquinolyl)amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL339715; VUF8510; VUF-8510; BDBM50067088; 3-methoxy-N-[3-(2-pyridyl)-1-isoquinolyl]benzamidine; 3-Methoxy-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamidine
Click to Show/Hide
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||||
| Activity |
Ki = 980000 nM
|
[24] | |||
| Compound Name |
5'-Amino-5'-deoxyadenosine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Adenosine, 5'-amino-5'-deoxy-; (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(aminomethyl)tetrahydrofuran-3,4-diol; CHEMBL302376; (2R,3S,4R,5R)-2-(AMINOMETHYL)-5-(6-AMINOPURIN-9-YL)OXOLANE-3,4-DIOL; NSC 238990; 5'-NH2-Ado; SCHEMBL506313; 5'-amino-5'-deoxy-adenosine; 2-Aminomethyl-5-(6-amino-purin-9-yl)-tetrahydro-furan-3,4-diol; 5''-amino-5''-deoxyadenosine; Adenosine,5'-amino-5'-deoxy-; CTK8F6723; 5'-Amino-5'-deoxy-D-adenosine; ZINC3814316; 7053AA; BDBM50090850; MFCD04118083; AKOS016009578; SDCCGSBI-0633680.P001; AC-27389; Adenosine, 5'-amino-5'-deoxy- (8CI)(9CI); adenosine, 5'-amino-5'-deoxy-, hydrochloride; Q27455878; 5''-Amino-5''-deoxyadenosine; NSC 238990; AC1L37DI;; (2R,3S,4R,5R)-2-Aminomethyl-5-(6-amino-purin-9-yl)-tetrahydro-furan-3,4-diol
Click to Show/Hide
|
||||
| Activity |
Ki = 1000000 nM
|
[26] | |||
| Compound Name |
2'-Amino-2'-deoxyadenosine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2'-Deoxy-2'-aminoadenosine; (2R,3S,4R,5R)-4-amino-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol; CHEMBL133809; MFCD06657636; 4-Amino-5-(6-amino-purin-9-yl)-2-hydroxymethyl-tetrahydro-furan-3-ol; Adenosine, 2'-amino-2'-deoxy-; 2''-AMINO-2''-DEOXYADENOSINE; NSC 324326; ADENOSINE, 2'-AMINO,-2'-DEOXY-; 2-Amino-2-deoxyadenosine; SCHEMBL598130; cid_100053; Adenosine,2'-amino-2'-deoxy-; CTK4A2778; KS-00000Y8O; 0963AA; ANW-64049; BDBM50106536; HG1019; ZINC53204366; 9-(2-Amino-2-deoxyfuranosyl)adenine; AKOS016003830; DB04102; AS-49373; AB0088000; DB-020372; X-1456; 414A810; Q27452838
Click to Show/Hide
|
||||
| Activity |
Ki = 1000000 nM
|
[26] | |||
| Compound Name |
7-Tert-Butyl-2-(2-furanyl)-7H-1,3,3a,5,6,7-hexaaza-as-indacene-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL414620; BDBM50094693; 8-tert-butyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine; 8-tert-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Click to Show/Hide
|
||||
| Activity |
Ki = 1148153.62 nM
|
[5] | |||
| Compound Name |
1-[2-(4,6-Dimethyl-2-pyrimidinyl)-4-quinazolinyl]-3-phenylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL72030; BDBM50088459; 1-[2-(4,6-Dimethyl-pyrimidin-2-yl)-quinazolin-4-yl]-3-phenyl-urea
Click to Show/Hide
|
||||
| Activity |
Ki = 1260000 nM
|
[13] | |||
| Compound Name |
[Imino(3-methylphenyl)methyl](3-(2-pyridyl)isoquinolyl)amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL129373; VUF8514; VUF-8514; BDBM50067086; 3-methyl-N-[3-(2-pyridyl)-1-isoquinolyl]benzamidine; 3-Methyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 1300000 nM
|
[24] | |||
| Compound Name |
Tert-butyl N-[4-[[4-(furan-2-yl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]-4-oxobutyl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL359531; BDBM50158782
Click to Show/Hide
|
||||
| Activity |
Ki = 1479108.39 nM
|
[5] | |||
| Compound Name |
11-(Cyclohexylmethyl)-4-(furan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL179349; BDBM50158779; 8-Cyclohexylmethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Click to Show/Hide
|
||||
| Activity |
Ki = 1737800.83 nM
|
[5] | |||
| Compound Name |
1-(2-Phenyl-4-quinazolinyl)-3-(3-methoxyphenyl)urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL74112; BDBM50088461; 1-(3-Methoxy-phenyl)-3-(2-phenyl-quinazolin-4-yl)-urea
Click to Show/Hide
|
||||
| Activity |
Ki = 2040000 nM
|
[13] | |||
| Compound Name |
4-(Furan-2-yl)-11-octyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL360448; BDBM50158760; 2-Furan-2-yl-8-octyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Click to Show/Hide
|
||||
| Activity |
Ki = 2041737.94 nM
|
[5] | |||
| Compound Name |
[(3,4-Dichlorophenyl)iminomethyl](3-(2-pyridyl)isoquinolyl)amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL338501; VUF8471; VUF-8471; BDBM50067087; 3,4-dichloro-N-[3-(2-pyridyl)-1-isoquinolyl]benzamidine; 3,4-Dichloro-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 2300000 nM
|
[24] | |||
| Compound Name |
4-Chloro-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL339097; VUF-8470; BDBM50067094
Click to Show/Hide
|
||||
| Activity |
Ki = 2300000 nM
|
[24] | |||
| Compound Name |
Tert-butyl N-[4-[[4-(furan-2-yl)-11-(3-methylbutyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]-4-oxobutyl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL367773; BDBM50158768
Click to Show/Hide
|
||||
| Activity |
Ki = 2511886.43 nM
|
[5] | |||
| Compound Name |
2,6-Dimethyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL420517; BDBM50067110
Click to Show/Hide
|
||||
| Activity |
Ki = 2600000 nM
|
[12] | |||
| Compound Name |
1-Chloro-3-pyridin-2-ylisoquinoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL128517; 1-chloro-3-(pyridin-2-yl)isoquinoline; SCHEMBL4766375; 1-chloro-3-(2-pyridyl)isoquinoline; BDBM50067074; 1-Chloro-3-pyridin-2-yl-isoquinoline; DA-04619; FT-0711621
Click to Show/Hide
|
||||
| Activity |
Ki = 2600000 nM
|
[24] | |||
| Compound Name |
N-(2,6-Dimethyl-benzoyl)-2,6-dimethyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL128269; BDBM50067090; N-[3-(2-Pyridinyl)isoquinoline-1-yl]-N-(2,6-dimethylbenzoyl)-2,6-dimethylbenzamide
Click to Show/Hide
|
||||
| Activity |
Ki = 3200000 nM
|
[24] | |||
| Compound Name |
4-(Furan-2-yl)-11-(2-naphthalen-1-ylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL146658; BDBM50094684; 7-[2-(1-Naphthyl)ethyl]-2-(2-furanyl)-7H-1,3,3a,5,6,7-hexaaza-as-indacene-4-amine
Click to Show/Hide
|
||||
| Activity |
Ki = 3388441.56 nM
|
[5] | |||
| Compound Name |
1-(Methylthio)-3-pyridin-2-ylisoquinoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL129027; BDBM50067073; ZINC13781342; 1-(Methylthio)-3-(2-pyridinyl)isoquinoline; 1-Methylsulfanyl-3-pyridin-2-yl-isoquinoline; isoquinoline, 1-(methylthio)-3-(2-pyridinyl)-
Click to Show/Hide
|
||||
| Activity |
Ki = 3900000 nM
|
[24] | |||
| Compound Name |
N-(2-Pyridin-2-yl-quinazolin-4-yl)-formamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL131713; SCHEMBL10709371; BDBM50067108; N'-(2-pyridin-2-ylquinazolin-4-yl)methanimidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 4000000 nM
|
[12] | |||
| Compound Name |
4-(Furan-2-yl)-11-[2-(2,4,5-tribromophenyl)ethyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL144972; BDBM50094678; 2-Furan-2-yl-8-(2,4,5-tribromo-benzyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine; 7-[2-(2,4,5-Tribromophenyl)ethyl]-2-(2-furanyl)-7H-1,3,3a,5,6,7-hexaaza-as-indacene-4-amine
Click to Show/Hide
|
||||
| Activity |
Ki = 4466835.92 nM
|
[5] | |||
| Compound Name |
1-Ethyl-3-(2-pyridinyl)isoquinoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL129406; SCHEMBL11366714; 1-ethyl-3-pyridin-2-ylisoquinoline; BDBM50067093; 1-Ethyl-3-pyridin-2-yl-isoquinoline
Click to Show/Hide
|
||||
| Activity |
Ki = 5100000 nM
|
[24] | |||
| Compound Name |
1-Methoxy-3-(2-pyridinyl)isoquinoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL340231; BDBM50067078; 1-Methoxy-3-pyridin-2-yl-isoquinoline
Click to Show/Hide
|
||||
| Activity |
Ki = 5600000 nM
|
[24] | |||
| Compound Name |
3-Chloro-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
TCMDC-123745; CHEMBL339050; DNDI1417638; BDBM50067077; 3-Chloro-N-[3-(2-pyridinyl)-1-isoquinolinyl]benzenecarbimide amide
Click to Show/Hide
|
||||
| Activity |
Ki = 7800000 nM
|
[24] | |||
| Compound Name |
N-(2-Pyridin-2-ylquinazolin-4-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL131068; SCHEMBL10705748; BDBM50067106; N-(2-Pyridin-2-yl-quinazolin-4-yl)-acetamide; N-[2-(2-Pyridinyl)quinazoline-4-yl]acetamide
Click to Show/Hide
|
||||
| Activity |
Ki = 11000000 nM
|
[12] | |||
| Compound Name |
1-Phenyl-3-pyridin-2-ylisoquinoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL128841; NSC608425; SCHEMBL11366802; BDBM50067072; ZINC12940228; 1-Phenyl-3-(2-pyridinyl)isoquinoline; 1-Phenyl-3-pyridin-2-yl-isoquinoline; NSC-608425
Click to Show/Hide
|
||||
| Activity |
Ki = 12000000 nM
|
[24] | |||
| Compound Name |
N-(3-Pyridin-2-yl-isoquinolin-1-yl)-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL128520; SCHEMBL10704613; VUF-8346; BDBM50067104; ZINC13781353; N-(3-pyridin-2-ylisoquinolin-1-yl)acetamide
Click to Show/Hide
|
||||
| Activity |
Ki = 13000000 nM
|
[12] | |||
| Compound Name |
1-(Methylsulfonyl)-3-pyridin-2-ylisoquinoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL128179; BDBM50067083; 1-Methanesulfonyl-3-pyridin-2-yl-isoquinoline; 1-(Methylsulfonyl)-3-(2-pyridinyl)isoquinoline; isoquinoline, 1-(methylsulfonyl)-3-(2-pyridinyl)-
Click to Show/Hide
|
||||
| Activity |
Ki = 15000000 nM
|
[24] | |||
| Compound Name |
(2-Amino-4H-indeno[1,2-d][1,3]thiazol-5-yl) acetate;hydroiodide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL39388; BDBM50451380
Click to Show/Hide
|
||||
| Activity |
EC50 = 15848931.92 nM
|
[25] | |||
| Compound Name |
N-(3-Pyridin-2-yl-isoquinolin-1-yl)-formamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL341025; BDBM50067076; ZINC13781344
Click to Show/Hide
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||||
| Activity |
Ki = 20000000 nM
|
[12] | |||
| Compound Name |
4-Hydroxy-2-(2-pyridyl)quinazoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL128427; MFCD01330934; 2-pyridin-2-yl-1H-quinazolin-4-one; 2-(pyridin-2-yl)quinazolin-4(3H)-one; SMR000058004; MLS000036917; SCHEMBL10709261; 2-(7-pyridyl) quinazol-4-one; CTK0J1954; DTXSID90349793; 2-Pyridin-2-yl-quinazolin-4-ol; 2-(2-Pyridinyl)quinazoline-4-ol; HMS2185A03; ZINC8579987; BDBM50067109; STL026532; AKOS005640087; AKOS030521189; MCULE-1548013743; NCGC00019934-01; NCGC00019934-02; 2-(Pyridin-2-yl)quinazolin-4(1H)-one; CS-12642; SY129053; 4(1H)-Quinazolinone, 2-(2-pyridinyl)-; DB-086638; 2-(pyridin-2-yl)-3,4-dihydroquinazolin-4-one; Z666587004
Click to Show/Hide
|
||||
| Activity |
Ki = 22000000 nM
|
[12] | |||
| Compound Name |
3-Pyridin-2-yl-2H-isoquinolin-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL128943; SCHEMBL4772827; 3-Pyridin-2-yl-isoquinolin-1-ol; 3-(2-Pyridinyl)isoquinoline-1-ol; ZINC8855193; BDBM50067091
Click to Show/Hide
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||||
| Activity |
Ki = 27000000 nM
|
[12] | |||
| Compound Name |
N-Acetyl-N-(3-pyridin-2-ylisoquinolin-1-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL340806; BDBM50067085; N-Acetyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-acetamide; acetamide, N-acetyl-N-[3-(2-pyridinyl)-1-isoquinolinyl]-; 1,1'-[[3-(2-Pyridinyl)isoquinoline-1-yl]imino]bisethanone
Click to Show/Hide
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||||
| Activity |
Ki = 35000000 nM
|
[24] | |||
| Compound Name |
N-(3-Pyridin-2-yl-isoquinolin-1-yl)-isobutyramide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL335744; BDBM50067115; N-[3-(2-Pyridinyl)-1-isoquinolinyl]-2-methylpropanamide
Click to Show/Hide
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||||
| Activity |
Ki = 48000000 nM
|
[12] | |||
| Compound Name |
1-(2-Tert-Butyl-4-quinazolinyl)-3-phenylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL72007; BDBM50088464; 1-(2-tert-Butyl-quinazolin-4-yl)-3-phenyl-urea
Click to Show/Hide
|
||||
| Activity |
Ki = 78700000 nM
|
[13] | |||
| Compound Name |
2,2,2-Trifluoro-N-(2-pyridin-2-yl-quinazolin-4-yl)-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL419797; SCHEMBL10706033; BDBM50067112; 2,2,2-trifluoro-N-(2-pyridin-2-ylquinazolin-4-yl)acetamide; 2,2,2-Trifluoro-N-[2-(2-pyridinyl)quinazoline-4-yl]acetamide
Click to Show/Hide
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||||
| Activity |
Ki = 86000000 nM
|
[12] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Novel 1,3-disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) xanthines: high affinity and selective A2B adenosine receptor antagonists. J Med Chem. 2006 Jun 15;49(12):3682-92. | ||||
| REF 2 | Synthesis and biological activities of flavonoid derivatives as A3 adenosine receptor antagonists. J Med Chem. 1996 Jun 7;39(12):2293-301. | ||||
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| REF 4 | Synthesis and biological activity of tricyclic cycloalkylimidazo-, pyrimido- and diazepinopurinediones. Eur J Med Chem. 2011 Sep;46(9):3590-607. | ||||
| REF 5 | QSAR of adenosine receptor antagonists: Exploring physicochemical requirements for binding of pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives with human adenosine A(3) receptor subtype. Bioorg Med Chem Lett. 2011 Jan 15;21(2):818-23. | ||||
| REF 6 | 8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A2A and A2B receptors ligands. Bioorg Med Chem. 2009 Apr 1;17(7):2812-22. | ||||
| REF 7 | 8-(2-Furyl)adenine derivatives as A1 adenosine receptor ligands. Eur J Med Chem. 2013;70:525-35. | ||||
| REF 8 | Scaffold decoration at positions 5 and 8 of 1,2,4-triazolo[1,5-c]pyrimidines to explore the antagonist profiling on adenosine receptors: a preliminary structure-activity relationship study. J Med Chem. 2014 Jul 24;57(14):6210-25. | ||||
| REF 9 | Discovery of simplified N?substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: efficient synthetic approaches, biological evaluations and molecular docking studies. Bioorg Med Chem. 2014 Mar 1;22(5):1751-65. | ||||
| REF 10 | Synthesis and pharmacological evaluation of dual acting antioxidant A(2A) adenosine receptor agonists. J Med Chem. 2012 Apr 12;55(7):3521-34. | ||||
| REF 11 | Methanocarba analogues of purine nucleosides as potent and selective adenosine receptor agonists. J Med Chem. 2000 Jun 1;43(11):2196-203. | ||||
| REF 12 | A novel class of adenosine A3 receptor ligands. 2. Structure affinity profile of a series of isoquinoline and quinazoline compounds. J Med Chem. 1998 Oct 8;41(21):3994-4000. | ||||
| REF 13 | Isoquinoline and quinazoline urea analogues as antagonists for the human adenosine A(3) receptor. J Med Chem. 2000 Jun 1;43(11):2227-38. | ||||
| REF 14 | A facile and novel synthesis of N(2)-, C(6)-substituted pyrazolo[3,4-d]pyrimidine-4 carboxylate derivatives as adenosine receptor antagonists. Eur J Med Chem. 2015 Mar 6;92:784-98. | ||||
| REF 15 | 5'-Carbamoyl derivatives of 2'-C-methyl-purine nucleosides as selective A1 adenosine receptor agonists: affinity, efficacy, and selectivity for A1 ... Bioorg Med Chem. 2008 Jan 1;16(1):336-53. | ||||
| REF 16 | Design, synthesis, and biological evaluation of LNA nucleosides as adenosine A3 receptor ligands. Bioorg Med Chem. 2007 Aug 15;15(16):5440-7. | ||||
| REF 17 | Orthogonal activation of the reengineered A3 adenosine receptor (neoceptor) using tailored nucleoside agonists. J Med Chem. 2006 May 4;49(9):2689-702. | ||||
| REF 18 | Discovery of 7-(Prolinol-N-yl)-2-phenylamino-thiazolo[5,4-d]pyrimidines as Novel Non-Nucleoside Partial Agonists for the A2A Adenosine Receptor: Prediction from Molecular Modeling. J Med Chem. 2016 Jun 23;59(12):5922-8. | ||||
| REF 19 | Structure-activity relationships of 4-(phenylethynyl)-6-phenyl-1,4-dihydropyridines as highly selective A3 adenosine receptor antagonists. J Med Chem. 1997 Aug 1;40(16):2596-608. | ||||
| REF 20 | Synthesis of eudistomin D analogues and its effects on adenosine receptors. Bioorg Med Chem. 2008 Apr 1;16(7):3825-30. | ||||
| REF 21 | 5,7-Disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazines as pharmacological tools to explore the antagonist selectivity profiles toward adenosine receptors. Eur J Med Chem. 2016 Jan 27;108:529-541. | ||||
| REF 22 | Tetrahydrobenzothiophenone derivatives as a novel class of adenosine receptor antagonists. J Med Chem. 1996 Jan 19;39(2):398-406. | ||||
| REF 23 | Thiazole and thiadiazole analogues as a novel class of adenosine receptor antagonists. J Med Chem. 2001 Mar 1;44(5):749-62. | ||||
| REF 24 | A novel class of adenosine A3 receptor ligands. 1. 3-(2-Pyridinyl)isoquinoline derivatives. J Med Chem. 1998 Oct 8;41(21):3987-93. | ||||
| REF 25 | 2-Aminothiazoles: a new class of agonist allosteric enhancers of A(1) adenosine receptors. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1563-6. | ||||
| REF 26 | Neoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides. J Med Chem. 2001 Nov 22;44(24):4125-36. | ||||
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