Target Interacting Proteins |
Top |
Acyltransferases |
[+] 5 Acyltransferases |
+ |
Interacting Target Name |
Histone acetyltransferase p300 (EP300) |
Clinical trial Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Protein propionyltransferase p300; p300 HAT; P300; Histone crotonyltransferase p300; Histone butyryltransferase p300; E1A-associated protein p300; E1Aassociated protein p300 |
Evidence Score (E-score) |
5 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[1] |
2 |
Fluorescence Resonance Energy Transfer |
[2] |
3 |
Protein-peptide |
[3] |
4 |
Reconstituted Complex |
[1] |
5 |
Yeast two hybrid |
[1] |
Interacting Protein Name |
Nuclear receptor coactivator 1 (NCOA1) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
F.SRC.1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74 |
Evidence Score (E-score) |
4 Experimental Evidences |
+ |
1 |
Fluorescence Resonance Energy Transfer |
[2] |
2 |
Protein-peptide |
[3] |
3 |
Reconstituted Complex |
[4] |
4 |
Yeast two hybrid |
[5] |
Interacting Target Name |
Nuclear receptor coactivator 3 (NCOA3) |
Literature-reported Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
TRAM-1; TRAM1; Thyroid hormone receptor activator molecule 1; Steroid receptor coactivator protein 3; SRC-3; Receptor-associated coactivator 3; RAC-3; RAC3; PCIP; NCoA-3; Class E basic helix-loop-helix protein 42; CBP-interacting protein; bHLHe42; Amplified in breast cancer-1 protein; Amplified in breast cancer 1 protein; AIB1 (SRC-3); AIB-1; AIB1; ACTR |
Evidence Score (E-score) |
3 Experimental Evidences |
+ |
1 |
Fluorescence Resonance Energy Transfer |
[2] |
2 |
Protein-peptide |
[3] |
3 |
Reconstituted Complex |
[4] |
Interacting Target Name |
Tripartite motif-containing 24 (TRIM24) |
Literature-reported Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Tripartite motif-containing protein 24; Transcription intermediary factor 1-alpha; TIF1-alpha; TIF1A; TIF1; RNF82; RING-type E3 ubiquitin transferase TIF1-alpha; RING finger protein 82; E3 ubiquitin-protein ligase TRIM24 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Fluorescence Resonance Energy Transfer |
[2] |
2 |
Protein-peptide |
[6] |
Interacting Protein Name |
Histone acetyltransferase KAT5 (KAT5) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
ESA1; HTATIP; HTATIP1; PLIP; TIP; TIP60; ZC2HC5; cPLA2 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Protein-peptide |
[6] |
2 |
Reconstituted Complex |
[7] |
Auxiliary transporters |
[+] 1 Auxiliary transporters |
+ |
Interacting Target Name |
Caveolin 1 (CAV1) |
Literature-reported Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Caveolin-1; Caveolin1; Cav-1; CAV |
Evidence Score (E-score) |
4 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[8] |
2 |
Co-fractionation |
[8] |
3 |
Co-localization |
[8] |
4 |
Yeast two hybrid |
[8] |
Carbon-nitrogen hydrolases |
[+] 2 Carbon-nitrogen hydrolases |
+ |
Interacting Target Name |
Histone deacetylase 4 (HDAC4) |
Clinical trial Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
KIAA0288; HD4 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[9] |
2 |
Reconstituted Complex |
[10] |
Interacting Target Name |
Histone deacetylase 3 (HDAC3) |
Clinical trial Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
SMAP45; RPD3-2; RPD32; HD3 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[11] |
2 |
Reconstituted Complex |
[10] |
Kinases |
[+] 2 Kinases |
+ |
Interacting Target Name |
ERK activator kinase 1 (MEK1) |
Clinical trial Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
PRKMK1; MKK1; Mitogen-activated protein kinase kinase 1; MEK 1; MAPKK 1; MAPK/ERKkinase 1; MAPK/ERK kinase 1; MAP kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 1 |
Evidence Score (E-score) |
3 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[8] |
2 |
Co-fractionation |
[8] |
3 |
Reconstituted Complex |
[12] |
Interacting Target Name |
Cyclin-dependent kinase 5 (CDK5) |
Patented-recorded Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
TPKII catalytic subunit; Tau protein kinase II catalytic subunit; Serine/threonine-protein kinase PSSALRE; Serine/threonine protein kinase PSSALRE; Proline-directed protein kinase F(A) (PDPK F(A)); Proline-directed protein kinase 33 kDa subunit; PDPK; Cyclin-dependent-like kinase 5; Cyclin-dependent kinase 5 (CDK5); Cell division protein kinase 5; CDKN5 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[13] |
2 |
Biochemical Activity |
[14] |
Mediator complexes |
[+] 1 Mediator complexes |
+ |
Interacting Protein Name |
Mediator of RNA polymerase II transcription subunit 1 (MED1) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
CRSP1; CRSP200; DRIP205; DRIP230; PBP; PPARBP; PPARGBP; RB18A; TRAP220; TRIP2 |
Evidence Score (E-score) |
4 Experimental Evidences |
+ |
1 |
Fluorescence Resonance Energy Transfer |
[2] |
2 |
Protein-peptide |
[3] |
3 |
Reconstituted Complex |
[4] |
4 |
Yeast two hybrid |
[15] |
Nuclear hormone receptors |
[+] 4 Nuclear hormone receptors |
+ |
Interacting Target Name |
Retinoic acid receptor RXR-alpha (RXRA) |
Successful Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
RXRalpha; Retinoid X receptor alpha; Nuclear receptor subfamily 2 group B member 1; NR2B1 |
Evidence Score (E-score) |
6 Experimental Evidences |
+ |
1 |
Affinity Capture-MS |
[16] |
2 |
Affinity Capture-Western |
[17] |
3 |
Co-crystal Structure |
[18] |
4 |
Co-localization |
[19] |
5 |
Reconstituted Complex |
[20] |
6 |
Yeast two hybrid |
[21] |
Interacting Target Name |
Orphan nuclear receptor SHP (NR0B2) |
Literature-reported Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Small heterodimer partner; SHP; Short heterodimer partner; Nuclear receptor subfamily 0 group B member 2 |
Evidence Score (E-score) |
3 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[22] |
2 |
Protein-peptide |
[3] |
3 |
Reconstituted Complex |
[22] |
Interacting Target Name |
Retinoic acid receptor RXR-beta (RXRB) |
Successful Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Retinoid X receptor beta; Nuclear receptor subfamily 2 group B member 2; NR2B2 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-MS |
[16] |
2 |
Affinity Capture-Western |
[23] |
Interacting Target Name |
Orphan nuclear receptor DAX-1 (NR0B1) |
Literature-reported Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Nuclear receptor subfamily 0 group B member 1; Nuclear receptor DAX-1; DSS-AHC critical region on the X chromosome protein 1; DAX1; AHC |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Protein-peptide |
[3] |
2 |
Reconstituted Complex |
[24] |
Oxidoreductases |
[+] 1 Oxidoreductases |
+ |
Interacting Protein Name |
Probable JmjC domain-containing histone demethylation protein 2C (JMJD1C) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
TRIP8 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Fluorescence Resonance Energy Transfer |
[2] |
2 |
Protein-peptide |
[3] |
Transcription regulators |
[+] 10 Transcription regulators |
+ |
Interacting Protein Name |
Nuclear receptor corepressor 1 (NCOR1) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
N.CoR; N.CoR1; PPP1R109; TRAC1; hN.CoR |
Evidence Score (E-score) |
6 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[19] |
2 |
Co-localization |
[25] |
3 |
Fluorescence Resonance Energy Transfer |
[26] |
4 |
Protein-peptide |
[3] |
5 |
Reconstituted Complex |
[27] |
6 |
Yeast two hybrid |
[13] |
Interacting Protein Name |
Nuclear receptor corepressor 2 (NCOR2) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
CTG26; N.CoR2; SMAP270; SMRT; SMRTE; SMRTE.tau; TNRC14; TRAC; TRAC.1; TRAC1 |
Evidence Score (E-score) |
4 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[19] |
2 |
Co-localization |
[25] |
3 |
Protein-peptide |
[3] |
4 |
Yeast two hybrid |
[21] |
Interacting Protein Name |
PPAR-gamma coactivator 1-alpha (PPARGC1A) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
LEM6; PGC.1(alpha); PGC.1v; PGC1; PGC1A; PPARGC1 |
Evidence Score (E-score) |
4 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[28] |
2 |
Protein-peptide |
[3] |
3 |
Reconstituted Complex |
[29] |
4 |
Yeast two hybrid |
[15] |
Interacting Protein Name |
Transcription factor p65 (RELA) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
NFKB3; p65 |
Evidence Score (E-score) |
4 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[30] |
2 |
Biochemical Activity |
[31] |
3 |
Reconstituted Complex |
[30] |
4 |
Yeast two hybrid |
[32] |
Interacting Target Name |
CREB-binding protein (CREBBP) |
Clinical trial Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
CREBbinding protein; CBP |
Evidence Score (E-score) |
3 Experimental Evidences |
+ |
1 |
Protein-peptide |
[3] |
2 |
Reconstituted Complex |
[33] |
3 |
Yeast two hybrid |
[34] |
Interacting Protein Name |
Nuclear receptor coactivator 2 (NCOA2) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
GRIP1; KAT13C; NCoA.2; SRC2; TIF2; bHLHe75 |
Evidence Score (E-score) |
3 Experimental Evidences |
+ |
1 |
Fluorescence Resonance Energy Transfer |
[2] |
2 |
Protein-peptide |
[3] |
3 |
Yeast two hybrid |
[15] |
Interacting Target Name |
Transcription factor Sp1 (SP1) |
Clinical trial Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
TSFP1 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[35] |
2 |
Reconstituted Complex |
[36] |
Interacting Target Name |
CCAAT/enhancer binding protein beta (CEBPB) |
Literature-reported Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Transcription factor CCAAT/enhancer-binding protein beta; Transcription factor 5; TCF-5; TCF5; PP9092; Nuclear factor NF-IL6; Liver-enriched inhibitory protein; Liver activator protein; LIP; LAP; CCAAT/enhancer-binding protein beta; C/EBP beta |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[37] |
2 |
Reconstituted Complex |
[36] |
Interacting Target Name |
High mobility group protein HMG-I/Y (HMGA1) |
Literature-reported Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
HMGIY; HMG-I(Y); High mobility group protein R; High mobility group protein HMG-I/HMG-Y; High mobility group protein A1; High mobility group AT-hook protein 1 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Reconstituted Complex |
[36] |
2 |
Yeast two hybrid |
[38] |
Interacting Protein Name |
Activating signal cointegrator 1 (TRIP4) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
ASC.1; ASC1; HsT17391; ZC2HC5 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Fluorescence Resonance Energy Transfer |
[2] |
2 |
Protein-peptide |
[3] |
Other proteins |
[+] 5 Other proteins |
+ |
Interacting Target Name |
Nuclear receptor coactivator 4 (NCOA4) |
Literature-reported Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
RFG; Ret-activating protein ELE1; Nuclear receptor coactivator 4; NCoA-4; ELE1; ARA70 (dARA70N); ARA70; Androgen receptor-associated protein of 70 kDa; Androgen receptor coactivator 70 kDa protein; 70 kDa AR-activator; 70 kDa androgen receptor coactivator |
Evidence Score (E-score) |
3 Experimental Evidences |
+ |
1 |
Protein-peptide |
[6] |
2 |
Reconstituted Complex |
[5] |
3 |
Yeast two hybrid |
[5] |
Interacting Protein Name |
Nuclear receptor-interacting protein 1 (NRIP1) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
RIP140 |
Evidence Score (E-score) |
3 Experimental Evidences |
+ |
1 |
Fluorescence Resonance Energy Transfer |
[2] |
2 |
Protein-peptide |
[3] |
3 |
Reconstituted Complex |
[39] |
Interacting Protein Name |
Zinc finger HIT domain-containing protein 3 (ZNHIT3) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
TRIP3 |
Evidence Score (E-score) |
3 Experimental Evidences |
+ |
1 |
Fluorescence Resonance Energy Transfer |
[2] |
2 |
Protein-peptide |
[3] |
3 |
Reconstituted Complex |
[3] |
Interacting Protein Name |
Glutamate receptor-interacting protein 1 (GRIP1) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
GRIP |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Reconstituted Complex |
[4] |
2 |
Yeast two hybrid |
[40] |
Interacting Protein Name |
Nuclear receptor coactivator 6 (NCOA6) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
AIB3; ASC2; NRC; PRIP; RAP250; TRBP |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[41] |
2 |
Protein-peptide |
[3] |