Protein-Protein Interaction Details
Protein General Information (TTD Target) | Top | ||||
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Full Name | High mobility group protein HMG-I/Y (HMGA1) | Literature-reported | Target Info | ||
UniProt ID | HMGA1_HUMAN | ||||
Gene Name | HMGA1 | ||||
Gene ID | 3159 |
Interacting TTD Target Information | Top | ||||
---|---|---|---|---|---|
Interacting Successful Target(s) | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) | Target Info | PPI Info | [1] | |
Interacting Clinical trial Target(s) | Casein kinase II alpha (CSNK2A1) | Target Info | PPI Info | [2] | |
CREB-binding protein (CREBBP) | Target Info | PPI Info | [3] | ||
Transcription factor Sp1 (SP1) | Target Info | PPI Info | [4] |
References | Top | ||||
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REF 1 | The insulin receptor: a new anticancer target for peroxisome proliferator-activated receptor-gamma (PPARgamma) and thiazolidinedione-PPARgamma agonists. Endocr Relat Cancer. 2008 Mar;15(1):325-35. | ||||
REF 2 | A bead-based approach for large-scale identification of in vitro kinase substrates. Proteomics. 2011 Dec;11(24):4632-7. | ||||
REF 3 | Acetylation of HMG I(Y) by CBP turns off IFN beta expression by disrupting the enhanceosome. Mol Cell. 1998 Oct;2(4):457-67. | ||||
REF 4 | A nucleoprotein complex containing Sp1, C/EBP beta, and HMGI-Y controls human insulin receptor gene transcription. Mol Cell Biol. 2003 Apr;23(8):2720-32. |
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