| References |
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| REF 1 |
Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. Sci Signal. 2013 Nov 19;6(302):rs15.
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| REF 2 |
Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in -Catenin-Active Cancers. Cell Syst. 2016 Sep 28;3(3):302-316.e4.
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| REF 3 |
OncoPPi-informed discovery of mitogen-activated protein kinase kinase 3 as a novel binding partner of c-Myc. Oncogene. 2017 Oct 19;36(42):5852-5860.
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| REF 4 |
Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1. Mol Syst Biol. 2013 Dec 22;9:713.
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| REF 5 |
Aerobic glycolysis tunes YAP/TAZ transcriptional activity. EMBO J. 2015 May 12;34(10):1349-70.
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| REF 6 |
PTPN14 is required for the density-dependent control of YAP1. Genes Dev. 2012 Sep 1;26(17):1959-71.
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| REF 7 |
Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family. Mol Cell Proteomics. 2016 Sep;15(9):3030-44.
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| REF 8 |
Ligand binding to WW tandem domains of YAP2 transcriptional regulator is under negative cooperativity. FEBS J. 2014 Dec;281(24):5532-51.
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| REF 9 |
Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway. Cancer Res. 2008 Apr 15;68(8):2789-94.
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| REF 10 |
Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP. Genes Dev. 2010 Nov 1;24(21):2430-9.
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| REF 11 |
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP). J Biol Chem. 2008 Oct 10;283(41):27534-46.
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| REF 12 |
Tumor suppressor LATS1 is a negative regulator of oncogene YAP. J Biol Chem. 2008 Feb 29;283(9):5496-509.
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| REF 13 |
RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein. Mol Cell. 2007 Sep 21;27(6):962-75.
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| REF 14 |
RAR Downregulation Contributes to Colorectal Tumorigenesis and Metastasis by Derepressing the Hippo-Yap Pathway. Cancer Res. 2016 Jul 1;76(13):3813-25.
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| REF 15 |
Kpm/Lats2 is linked to chemosensitivity of leukemic cells through the stabilization of p73. Blood. 2008 Nov 1;112(9):3856-66.
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| REF 16 |
Hippo pathway-dependent and -independent roles of RASSF6. Sci Signal. 2009 Sep 29;2(90):ra59.
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| REF 17 |
The E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradation. Mol Cell Biol. 2009 Feb;29(3):892-906.
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| REF 18 |
WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus. J Biol Chem. 2003 Aug 29;278(35):33334-41.
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| REF 19 |
Ligand-regulated association of ErbB-4 to the transcriptional co-activator YAP65 controls transcription at the nuclear level. Exp Cell Res. 2004 Apr 1;294(2):469-79.
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| REF 20 |
MEK1 promotes YAP and their interaction is critical for tumorigenesis in liver cancer. FEBS Lett. 2013 Dec 11;587(24):3921-7.
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| REF 21 |
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. Cell. 2012 Aug 17;150(4):780-91.
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| REF 22 |
The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73. Cell Death Differ. 2007 Apr;14(4):743-51.
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| REF 23 |
The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage. Mol Cell. 2005 May 13;18(4):447-59.
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| REF 24 |
PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop. Mol Cell. 2008 Dec 26;32(6):803-14.
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| REF 25 |
Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage. Mol Cell. 2008 Feb 15;29(3):350-61.
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| REF 26 |
TGF- Targets the Hippo Pathway Scaffold RASSF1A to Facilitate YAP/SMAD2 Nuclear Translocation. Mol Cell. 2016 Jul 7;63(1):156-66.
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| REF 27 |
Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signaling. Oncogene. 2002 Jul 25;21(32):4879-84.
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| REF 28 |
Structural basis for the versatile interactions of Smad7 with regulator WW domains in TGF- Pathways. Structure. 2012 Oct 10;20(10):1726-36.
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| REF 29 |
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways. Cell. 2009 Nov 13;139(4):757-69.
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| REF 30 |
A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev. 2011 Jun 15;25(12):1275-88.
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| REF 31 |
A regulatory circuit controlling Itch-mediated p73 degradation by Runx. J Biol Chem. 2008 Oct 10;283(41):27462-8.
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| REF 32 |
A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator. EMBO J. 1999 May 4;18(9):2551-62.
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| REF 33 |
A high-throughput approach for measuring temporal changes in the interactome. Nat Methods. 2012 Sep;9(9):907-9.
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| REF 34 |
A single point mutation in a group I WW domain shifts its specificity to that of group II WW domains. J Biol Chem. 1999 Jun 11;274(24):17284-9.
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| REF 35 |
Yes-associated protein and p53-binding protein-2 interact through their WW and SH3 domains. J Biol Chem. 2001 Apr 27;276(17):14514-23.
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| REF 36 |
Amot130 adapts atrophin-1 interacting protein 4 to inhibit yes-associated protein signaling and cell growth. J Biol Chem. 2013 May 24;288(21):15181-93.
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| REF 37 |
Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases. Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17368-73.
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| REF 38 |
The Nedd4-like ubiquitin E3 ligases target angiomotin/p130 to ubiquitin-dependent degradation. Biochem J. 2012 Jun 1;444(2):279-89.
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| REF 39 |
The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1. Mol Cell Biol. 2001 Nov;21(22):7617-28.
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