Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| MEP --- Cathepsin B | 4'-dimethylamino-biphenyl-4-carboxylic acid [1-(cyanomethyl-carbamoyl)-cyclohexyl]-amide | Drug Info |
| MEP --- Cathepsin B | (S)-3-Methyl-2-(toluene-4-sulfonylamino)-pentanoic acid [(R)-1-formyl-2-(1H-indol-3-yl)-ethyl]-amide | Drug Info |
| MEP --- Cathepsin B | 2-((3,5-bis(trifluoromethyl)phenyl)(p-tolyl)methylene)hydrazinecarbothioamide | Drug Info |
| MEP --- Cathepsin B | SID24801614 | Drug Info |
| MEP --- Cathepsin B | (S)-N-((S)-1-cyano-2-phenylethyl)-3-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)butanamide | Drug Info |
| MEP --- Cathepsin B | (S)-N-[(R)-1-Formyl-2-(1H-indol-3-yl)-ethyl]-2-(naphthalene-1-sulfonylamino)-propionamide | Drug Info |
| MEP --- Cathepsin B | (S)-benzyl 1-(cyanomethylamino)-3-(naphthalen-2-yl)-1-oxopropan-2-ylcarbamate | Drug Info |
| MEP --- Cathepsin B | N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(4-methylpiperazin-1-yl)benzamide | Drug Info |
| MEP --- Cathepsin B | (S)-3-Methyl-2-(naphthalene-1-sulfonylamino)-pentanoic acid [(S)-1-(4-hydroxy-benzyl)-2-oxo-ethyl]-amide | Drug Info |
| MEP --- Cathepsin B | 6-(biphenyl-3-ylmethylamino)-9-(3-hydroxypropyl)-9H-purine-2-carbonitrile | Drug Info |
| MEP --- Cathepsin B | (S)-2-(3-Isopropyl-ureido)-3-methyl-pentanoic acid [(R)-1-formyl-2-(1H-indol-3-yl)-ethyl]-amide | Drug Info |
| MEP --- Cathepsin B | benzyl (S)-1-((S)-4-(isopropylthio)-3-oxo-1-phenylbutan-2-ylamino)-4-methyl-1-oxopentan-2-ylcarbamate | Drug Info |
| MEP --- Cathepsin B | (4-Chloro-2-trifluoromethyl-phenyl)-carbamic acid 1-[(3-dimethylcarbamoyl-(1S)-1-phenethyl-allylcarbamoyl)-methyl]-(3R)-2-oxo-5-phenyl-2,3-dihydro-1Hbenzo[e][1,4]diazepin-3-ylmethyl ester | Drug Info |
| MEP --- Cathepsin B | (1S,2S)-2-bromo-7-oxa-5-aza-bicyclo[3.2.1]octan-6-one | Drug Info |
| MEP --- Cathepsin B | (S)-N-(1-(cyanomethylamino)-1-oxo-3-(3-(pyridin-4-yl)phenyl)propan-2-yl)benzamide | Drug Info |
| MEP --- Cathepsin B | {(S)-1-[(R)-1-Formyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butyl}-carbamic acid benzyl ester | Drug Info |
| MEP --- Cathepsin B | (R)-3-(2,3-difluorobenzylsulfonyl)-N-(1-cyanocyclopropyl)-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)propanamide | Drug Info |
| MEP --- Cathepsin B | [(3-Bromophenyl)-(3-acetoxyphenyl)-ketone]thiosemicarbazone | Drug Info |
| MEP --- Cathepsin B | (S)-N-(3-(3-chlorophenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)-1-naphthamide | Drug Info |
| MEP --- Cathepsin B | 4'-Iodo-biphenyl-4-carboxylic acid {1-[(S)-1-(2-diazo-acetyl)-butylcarbamoyl]-3-methyl-butyl}-amide | Drug Info |
| MEP --- Cathepsin B | (S)-N-((S)-1-cyano-3,3,3-trifluoropropyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)pentanamide | Drug Info |
| MEP --- Cathepsin B | 1-((3,5-bis(trifluoromethyl)phenyl)(thiophen-2-yl)methylene)thiosemicarbazide | Drug Info |
| MEP --- Cathepsin B | 3-[(R)-2-Cyano-2-((S)-2-phenylamino-3-m-tolyl-propionylamino)-ethoxymethyl]-benzoic acid | Drug Info |
| MEP --- Cathepsin B | (S)-4,4-dichloro-N-((S)-1-cyano-2-phenylethyl)-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)butanamide | Drug Info |
| MEP --- Cathepsin B | N-[2-(3-Morpholin-4-yl-ureido)-1-naphthalen-2-ylmethyl-2-oxo-ethyl]-2-[(E)-2-(naphthalene-2-sulfonyl)-vinylamino]-4-phenyl-butyramide | Drug Info |
| MEP --- Cathepsin B | (S)-3-Methyl-2-[3-(2-trifluoromethyl-phenyl)-ureido]-pentanoic acid [(R)-1-formyl-2-(1H-indol-3-yl)-ethyl]-amide | Drug Info |
| MEP --- Cathepsin B | 1-(4-Methoxyphenyl)-6,7-methylenedioxy-2-(4-methylthiophenyl-ureido)-2H-isoquinolin-3-one | Drug Info |
| MEP --- Cathepsin B | N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(2-(morpholinomethyl)thiazol-4-yl)benzamide | Drug Info |
| MEP --- Cathepsin B | [(S)-1-(2,5-Dioxo-1-phenethyl-piperidin-4-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester | Drug Info |
| MEP --- Cathepsin B | 9-(3-hydroxypropyl)-6-(3-(thiophen-2-yl)benzylamino)-9H-purine-2-carbonitrile | Drug Info |
| MEP --- Cathepsin B | 4'-(Piperazine-1-sulfonyl)-biphenyl-4-carboxylic acid [1-(cyanomethyl-carbamoyl)-cyclohexyl]-amide | Drug Info |
| MEP --- Cathepsin B | (S)-3-Methyl-2-(3-m-tolyl-ureido)-pentanoic acid [(R)-1-formyl-2-(1H-indol-3-yl)-ethyl]-amide | Drug Info |
| MEP --- Cathepsin B | 5-[(R)-2-Cyano-2-((S)-2-phenylamino-3-m-tolyl-propionylamino)-ethoxymethyl]-2-fluoro-benzoic acid | Drug Info |
| MEP --- Cathepsin B | benzyl (S)-1-((S)-4-(benzylthio)-3-oxo-1-phenylbutan-2-ylamino)-1-oxo-3-phenylpropan-2-ylcarbamate | Drug Info |
| MEP --- Cathepsin B | (S)-N-(3-(3-(1H-pyrazol-5-yl)phenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)benzamide | Drug Info |
| MEP --- Cathepsin B | [(3-Bromophenyl)-p-tolyl-ketone]thiosemicarbazone | Drug Info |
| MEP --- Cathepsin B | (S)-N-((S)-1-cyano-2-phenylethyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(1-(morpholine-4-carbonyl)cyclopropyl)biphenyl-4-yl)ethylamino)pentanamide | Drug Info |
| MEP --- Cathepsin B | 4'-[1-(2-Hydroxy-ethyl)-piperidin-4-yloxy]-biphenyl-4-carboxylic acid [1-(cyanomethyl-carbamoyl)-cyclohexyl]-amide | Drug Info |
| MEP --- Cathepsin B | (S)-N-(cyanomethyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)pentanamide | Drug Info |
| MEP --- Cathepsin B | Bis(3-bromophenyl)(4-hydroxy)thiosemicarbazone | Drug Info |
| MEP --- Cathepsin B | 6-(3-(furan-2-yl)benzylamino)-9-(3-hydroxypropyl)-9H-purine-2-carbonitrile | Drug Info |
| MEP --- Cathepsin B | (S)-3-Methyl-2-(3-naphthalen-1-yl-ureido)-pentanoic acid [(R)-1-formyl-2-(1H-indol-3-yl)-ethyl]-amide | Drug Info |
| MEP --- Cathepsin B | {(S)-1-[(R)-1-Formyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butyl}-carbamic acid tert-butyl ester | Drug Info |
| MEP --- Cathepsin B | (4-Chloro-2-trifluoromethyl-phenyl)-carbamic acid 1-[(3-dimethylcarbamoylallylcarbamoyl)-methyl]-(3R)-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylmethyl ester | Drug Info |
| MEP --- Cathepsin B | 2-(3-phenyl-1-(3-(trifluoromethyl)phenyl)allylidene)hydrazinecarbothioamide | Drug Info |
| MEP --- Cathepsin B | (S)-N-[(R)-1-Formyl-2-(1H-indol-3-yl)-ethyl]-2-(naphthalene-1-sulfonylamino)-3-phenyl-propionamide | Drug Info |
| MEP --- Cathepsin B | 2-((3,5-dichlorophenyl)(thiophen-2-yl)methylene)hydrazinecarbothioamide | Drug Info |
| MEP --- Cathepsin B | 4'-Isoxazol-5-yl-biphenyl-4-carboxylic acid [1-(cyanomethyl-carbamoyl)-cyclohexyl]-amide | Drug Info |
| MEP --- Cathepsin B | (E)-methyl4-(2-((R,Z)-3-((4-chloro-2-(trifluoromethyl)phenylcarbamoyloxy)methyl)-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-1-yl)acetamido)but-2-enoate | Drug Info |
| MEP --- Cathepsin B | 3-{(R)-2-Cyano-2-[(S)-2-(1,1-dimethyl-3-oxo-1,3-dihydro-isobenzofuran-5-ylamino)-3-m-tolyl-propionylamino]-ethoxymethyl}-benzoic acid | Drug Info |
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