Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CDK2 --- CDK1 | (3S,4S)-1-(3-(2-amino-6-ethylpyrimidin-4-yl)-4-hydroxyphenyl)pyrrolidine-3,4-diol | Drug Info |
| CDK2 --- CDK1 | (R)-1-amino-3-(6-(benzylamino)-9-isopropyl-9H-purin-2-ylamino)propan-2-ol | Drug Info |
| CDK2 --- CDK1 | 2-(pyridin-3-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one | Drug Info |
| CDK2 --- CDK1 | CHEMBL453629 | Drug Info |
| CDK2 --- CDK1 | GW416469X | Drug Info |
| CDK2 --- CDK1 | 4-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-N-methyl-benzenesulfonamide | Drug Info |
| CDK2 --- CDK4 | (8-Cyclopentyl-7-methoxy-quinazolin-2-yl)-(4-piperidin-1-yl-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | N*4*-[4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-N*1*,N*1*-dimethyl-2-nitro-benzene-1,4-diamine | Drug Info |
| CDK2 --- CDK4 | (3-Chloro-phenyl)-[4-(2,4-dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-amine | Drug Info |
| CDK2 --- CDK4 | 4-[2-(4-Hydroxy-phenylamino)-pyrimidin-4-yl]-3,5-dimethyl-1H-pyrrole-2-carbonitrile | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((5-(3-methoxyphenyl)thiophen-2-yl)methyl)-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | 3-(4-tert-Butylamino-2-trifluoromethyl-quinazolin-6-yl)-phenol | Drug Info |
| CDK2 --- Cyclin E | 3-Ethyl-6-isobutyl-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
| CDK2 --- Cyclin E | N-(trans-4-(6-(biphenyl-4-ylmethylamino)-9-isopropyl-9H-purin-2-ylamino)cyclohexyl)methanesulfonamide | Drug Info |
| CDK2 --- Cyclin E | N2-(3-aminocyclohexyl)-N6-(biphenyl-4-ylmethyl)-9-isopropyl-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | CHEMBL1197552 | Drug Info |
| CDK2 --- Cyclin E | 4-Butoxy-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethylamide | Drug Info |
| CDK2 --- GSK3 | N*5*-(4-Amino-cyclohexyl)-3-chloro-N*7*-[4-(thiophene-2-sulfonyl)-phenyl]-pyrazolo[1,5-a]pyrimidine-5,7-diamine | Drug Info |
| CAII --- CAI | 3-Bromo-4-(3-pentafluorophenyl-ureido)-benzenesulfonamide | Drug Info |
| CDK4 --- Cyclin E | N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)-4-oxo-2,4-dihydroindeno[1,2-c]pyrazol-5-yl]-2,2-dimethylhydrazinecarboxamide | Drug Info |
| CAII --- CAI | 4-Chloro-3-sulfamoyl-N-(4-sulfamoyl-benzyl)-benzamide | Drug Info |
| Ckit --- BRaf | 4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carbamoyl)phenylamino)methyl)-N-(3-morpholinopropyl)picolinamide | Drug Info |
| CAII --- CAI | (S)-2-(4-Chloro-3-sulfamoyl-benzoylamino)-pentanedioic acid | Drug Info |
| Cmet --- Ckit | N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenylcarbamothioyl)-2-phenylacetamide | Drug Info |
| CAII --- CAI | 1-(4-Aminophenyl)-4-benzoyl-5-phenyl-N-(5-sulfamoyl-1,3,4-thiadiazole-2-yl)-1H-pyrazole-3-carboxamide | Drug Info |
| COX2 --- 5LOX | 2,6-Dimethyl-4-(2-naphthalen-1-yl-vinyl)-phenol | Drug Info |
| CAII --- CAI | 4-(4-phenyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide | Drug Info |
| COX2 --- 5LOX | 2-Methoxy-6-propyl-4-(2-thiophen-2-yl-vinyl)-phenol | Drug Info |
| CAII --- CAI | 2,6-Diisopropyl-4-phenyl-1-{[4-(3-sulfamoyl-phenylsulfamoyl)-phenylcarbamoyl]-methyl}-pyridinium; perchlorate | Drug Info |
| CSrc --- CABL | (S)-1-(2-chloro-2-phenylethyl)-6-(2-morpholinoethylthio)-N-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| CAII --- CAI | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-Heptadecafluoro-nonanoic acid [2-(4-sulfamoyl-phenyl)-ethyl]-amide | Drug Info |
| CSrc --- CABL | N-(5-(4-bromobenzylthio)-1,3,4-thiadiazol-2-yl)-4-chlorobenzamide | Drug Info |
| CAII --- CAI | {[2-(Bis-carboxymethyl-amino)-ethyl]-[(4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-acetic acid | Drug Info |
| CSrc --- CABL | N-(5-(3-fluorobenzylthio)-1,3,4-thiadiazol-2-yl)-2-chlorobenzamide | Drug Info |
| CAII --- CAI | 4-(4-p-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide | Drug Info |
| CSrc --- CABL | N-benzyl-1-[2-chloro-2-(4-fluorophenyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| CAII --- CAI | 5-valproylamido-1,3,4-thiamidazole-2-sulfonamide | Drug Info |
| CSrc --- CABL | 1-(2-chloro-2-phenylethyl)-N-(3-chlorophenyl)-6-(ethylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| CAII --- CAI | 3-Fluoro-4-(nonafluorobutane-1-sulfonylamino)-benzenesulfonamide | Drug Info |
| CSrc --- CD221 | 2-(1H-Indol-3-yl)-2-oxo-N'-[4-(trifluoromethyl)benzoyl]acetohydrazide | Drug Info |
| CAII --- CAI | 5-(4-tert-butylphenylsulfonamido)-1,3,4-thiadiazole-2-sulfonamide | Drug Info |
| CSrc --- MEK | 4-(4-benzylphenylamino)-6-(2-morpholinoethylamino)-1,7-naphthyridine-3-carbonitrile | Drug Info |
| CAII --- CAI | 2,4,6-Trimethyl-1-[(3-methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-2-ylidenecarbamoyl)-methyl]-pyridinium; perchlorate | Drug Info |
| DHFR --- TYMS | N-{4-[(2-amino-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl)sulfanyl]benzoyl}-L-glutamic acid | Drug Info |
| CAII --- CAI | 2,6-Diethyl-4-phenyl-1-[(5-sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-methyl]-pyridinium; perchlorate | Drug Info |
| EGFR --- HER2 | CHEMBL532686 | Drug Info |
| CAII --- CAI | 2-Amino-N-({4-[3-methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2Z)-ylidenesulfamoyl]-phenylcarbamoyl}-methyl)-acetamide | Drug Info |
| EGFR --- Src | 2,2'-Dithiobis(1-methyl-5-hydroxy-N-phenyl-1H-indole-3-carboxamide) | Drug Info |
| CAII --- CAI | 5-{4-[(7-Chloro-2-oxo-2H-chromen-4-ylmethyl)-amino]-benzenesulfonylamino}-[1,3,4]thiadiazole-2-sulfonic acid amide | Drug Info |
| EGFR3 --- CSrc | 7-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.