Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CCKBR --- CCKAR | (+/-)-2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-4-chloro-N-(2-(4-chlorophenyl)propyl)benzamide | Drug Info |
| CCKBR --- CCKAR | {[(S)-2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-yl)-2-methyl-propionyl]-phenethyl-amino}-acetic acid | Drug Info |
| CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(2-nitro-phenyl)-ureido]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid | Drug Info |
| CCKBR --- CCKAR | {[2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-yl)-propionyl]-phenethyl-amino}-acetic acid | Drug Info |
| CD135 --- Ckit | N3-(4-morpholinophenyl)-1-(pyridin-2-yl)-1H-1,2,4-triazole-3,5-diamine | Drug Info |
| CD221 --- JNK1 | 2-fluoro-6-(2-(5-methoxy-1-(2-morpholinoacetyl)indolin-6-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzamide | Drug Info |
| CDK1 --- AuroraA | N-(4-(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylamino)phenyl)-N-(3-(piperidin-1-yl)propyl)methanesulfonamide | Drug Info |
| CDK1 --- CDK2 | 4-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-N,N-dimethyl-benzamide | Drug Info |
| CDK1 --- CDK4 | 2-(2-Bromo-phenyl)-5,7-dihydroxy-8-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-chromen-4-one | Drug Info |
| CDK1 --- GSK3 | 9-Bromo-2-iodo-5,12-dihydro-7H-benzo[2,3]azepino[4,5-b]indol-6-one | Drug Info |
| CDK1 --- GSK3 | SID530149 | Drug Info |
| CDK1 --- VEGFR | 4-(4-(2-aminopropan-2-yl)phenyl)-N-(3-bromophenyl)-5-chloropyrimidin-2-amine | Drug Info |
| CDK2 --- AKT | (R)-N-((3,4-dichlorophenyl)(1-methylazetidin-3-yl)methyl)isoquinoline-6-carboxamide | Drug Info |
| CDK2 --- AuroraA | (S)-4-{2-(4-Chloro-2-fluorophenylamino)-5-methylpyrimidin-4-yl}-N-{1-(3-chlorophenyl)-2-hydroxyethyl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- AuroraA | N,1,4,4-Tetramethyl-8-[(3-morpholin-4-ylphenyl)amino]-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- CDK1 | 2-oxo-3-[(4-sulfamoyl-phenyl)-hydrazono]-2,3-dihydro-1H-indole-5-carboxylic acid dimethylamide | Drug Info |
| CDK2 --- CDK1 | Xylocydine | Drug Info |
| CDK2 --- CDK1 | (6-Cyclohexylmethoxy-9H-purin-2-yl)-isopropyl-amine | Drug Info |
| CDK2 --- CDK1 | K00054 | Drug Info |
| CDK2 --- CDK1 | 4-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-N-methyl-benzamide | Drug Info |
| CDK2 --- CDK1 | 8-(1,1-dioxo-1lambda*6*-isothiazolidin-2-yl)-3-hydroxy-2-(4-hydroxy-phenyl)-6-methyl-chromen-4-one | Drug Info |
| CDK2 --- CDK1 | CHEMBL509406 | Drug Info |
| CDK2 --- CDK4 | 4-{[(6-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino]-methylene}-6-iodo-4H-isoquinoline-1,3-dione | Drug Info |
| CDK2 --- CDK4 | GW683003X | Drug Info |
| CDK2 --- CDK4 | [4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-phenyl-amine | Drug Info |
| CDK2 --- CSrc | 3-(4-(thiazol-2-yl)pyrimidin-2-ylamino)-5-(trifluoromethyl)phenol | Drug Info |
| CDK2 --- Cyclin E | (4-Butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)-m-tolyl-methanone | Drug Info |
| CDK2 --- Cyclin E | 3-Ethyl-6-(4-hydroxy-3-methyl-benzyl)-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((5-(pyridin-3-yl)thiophen-2-yl)methyl)-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | N-[5-(5-tert-Butyl-oxazol-2-ylmethylsulfanyl)-thiazol-2-yl]-benzenesulfonamide | Drug Info |
| CDK2 --- Cyclin E | 5-(2-chlorophenyl)-7-nitro-3-phenyl-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine | Drug Info |
| CDK2 --- Cyclin E | [4-(2-Hydroxy-ethoxy)-1H-pyrazolo[3,4-b]pyridin-5-yl]-phenyl-methanone | Drug Info |
| CDK2 --- Cyclin E | 5-Fluoro-3-(3-methoxy-1H-pyrrol-2-ylmethylene)-4-(S)-2-pyrrolidin-2-ylethynyl-1,3-dihydro-indol-2-one | Drug Info |
| CDK2 --- GSK3 | (Z)-N-(2-(dimethylamino)ethyl)-4-(5-((2-imino-4-oxothiazolidin-5-ylidene)methyl)furan-2-yl)benzenesulfonamide | Drug Info |
| CAII --- CAI | 1-[(5-Chloro-2,4-disulfamoyl-phenylcarbamoyl)-methyl]-2,6-diisopropyl-4-phenyl-pyridinium; perchlorate | Drug Info |
| CDK4 --- Cyclin E | 1-[3-(5-Methyl-thiophen-2-yl)-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl]-3-morpholin-4-yl-urea | Drug Info |
| CAII --- CAI | 1-[(2-Chloro-4-sulfamoyl-phenylcarbamoyl)-methyl]-2,6-diisopropyl-4-phenyl-pyridinium; perchlorate | Drug Info |
| Ckit --- BRaf | 4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carbamoyl)phenylamino)methyl)-N-ethylpicolinamide | Drug Info |
| CAII --- CAI | 4-Benzoyl-1-(3-(2-(1,3-dioxo-1-phenylbutan-2-ylidene)hydrazinyl)phenyl)-5-phenyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-1H-pyrazole-3-carboxamide | Drug Info |
| COX2 --- 5LOX | 3-(4-Biphenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide | Drug Info |
| CAII --- CAI | {Carboxymethyl-[(2-chloro-4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-acetic acid | Drug Info |
| COX2 --- 5LOX | 2,6-Dimethyl-4-[2-(5-methyl-thiophen-2-yl)-vinyl]-phenol | Drug Info |
| CAII --- CAI | 2-hydroxycinnamic acid | Drug Info |
| COX2 --- 5LOX | 3-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(Z)-ylidene]-dihydro-furan-2-one | Drug Info |
| CAII --- CAI | 2-(N-Methyl-guanidino)-N-[4-(5-sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-phenyl]-acetamide | Drug Info |
| CSrc --- CABL | 9-(2,6-dimethylstyryl)-N-(4-(dipropylphosphoryl)phenyl)-9H-purin-6-amine | Drug Info |
| CAII --- CAI | [(2-Hydroxy-phenyl)-(2-{(2-hydroxy-phenyl)-[2-(4-sulfamoyl-phenyl)-ethoxycarbonylmethyl]-amino}-ethyl)-amino]-acetic acid | Drug Info |
| CSrc --- CABL | 4-(7-(5-amino-2-chlorophenyl)-5-methylbenzo[e][1,2,4]triazin-3-ylamino)-N-(2-(pyrrolidin-1-yl)ethyl)benzenesulfonamide | Drug Info |
| CAII --- CAI | 2,4,6-Trimethyl-1-(2-sulfamoyl-benzothiazol-6-yloxycarbonylmethyl)-pyridinium; perchlorate | Drug Info |
| CSrc --- CABL | 2-(4-(phenethylamino)-1-styryl-1H-pyrazolo[3,4-d]pyrimidin-6-ylamino)ethanol | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.