Search for pathway correlated target
You are searching for: hsa04115
| T85799 Target Info |
Target Name | Cyclin-dependent kinase 4 (CDK4) | |
|---|---|---|---|
| Target type | Successful Target | ||
| Disease | Hormone receptor positive and HER2-negative advanced or metastatic breast cancer; Psoriasis vulgaris; | ||
| Drugs | Palbociclib | Drug Info | |
| T89361 Target Info |
Target Name | Cyclin-dependent kinase 6 (CDK6) | |
|---|---|---|---|
| Target type | Successful Target | ||
| Disease | Hormone receptor positive and HER2-negative advanced or metastatic breast cancer; Small-cell lung cancer; | ||
| Drugs | Palbociclib | Drug Info | |
| T38301 Target Info |
Target Name | Ribonucleoside-diphosphate reductase M2 (RRM2) | |
|---|---|---|---|
| Target type | Successful Target | ||
| Disease | Chronic myelogenous leukaemia; Pancreatic cancer; | ||
| Drugs | Gemcitabine | Drug Info | |
| T31309 Target Info |
Target Name | Apoptosis regulator Bcl-2 (BCL-2) | |
|---|---|---|---|
| Target type | Successful Target | ||
| Disease | Amyotrophic lateral sclerosis; Breast cancer; | ||
| Drugs | MCI-186 | Drug Info | |
| T12819 Target Info |
Target Name | E3 ubiquitin-protein ligase COP1 (RFWD2) | |
|---|---|---|---|
| Target type | Literature-reported Target | ||
| Disease | Not Available | ||
| Drugs | Not Available | ||
| T62449 Target Info |
Target Name | Checkpoint kinase-1 (CHK1) | |
|---|---|---|---|
| Target type | Clinical trial Target | ||
| Disease | Non-small-cell lung cancer; Small-cell lung cancer; | ||
| Drugs | UCN-01 | Drug Info | |
| T49898 Target Info |
Target Name | Cyclin-dependent kinase 1 (CDK1) | |
|---|---|---|---|
| Target type | Clinical trial Target | ||
| Disease | Breast cancer; Non-small-cell lung cancer; | ||
| Drugs | P276-00 | Drug Info | |
| T70176 Target Info |
Target Name | Cyclin-dependent kinase 2 (CDK2) | |
|---|---|---|---|
| Target type | Clinical trial Target | ||
| Disease | Thymic cancer; Anaplastic astrocytoma; | ||
| Drugs | R-roscovitine | Drug Info | |
| T00176 Target Info |
Target Name | Ubiquitin-protein ligase E3 Mdm2 (MDM2) | |
|---|---|---|---|
| Target type | Clinical trial Target | ||
| Disease | Haematological malignancy; Prolymphocytic leukaemia; | ||
| Drugs | RG7388 | Drug Info | |
| T56510 Target Info |
Target Name | Apoptosis regulator Bcl-xL (BCL-xL) | |
|---|---|---|---|
| Target type | Clinical trial Target | ||
| Disease | Myelofibrosis; Relapsed or refractory chronic lymphocytic leukaemia; | ||
| Drugs | ABT-263 | Drug Info | |
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