Drug Information
Drug General Information | Top | |||
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Drug ID |
D02UWB
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Former ID |
DIB018642
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Drug Name |
5-CT
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Synonyms |
5-carboxamidotryptamine
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C11H13N3O
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Canonical SMILES |
C1=CC2=C(C=C1C(=O)N)C(=CN2)CCN
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InChI |
1S/C11H13N3O/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10/h1-2,5-6,14H,3-4,12H2,(H2,13,15)
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InChIKey |
WKZLNEWVIAGNAW-UHFFFAOYSA-N
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CAS Number |
CAS 74885-09-9
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PubChem Compound ID | ||||
PubChem Substance ID |
4829303, 7978607, 8151296, 11110879, 11113509, 15244333, 26751726, 29221008, 46530749, 47216985, 47515530, 47589185, 48110665, 48334714, 49689464, 49983500, 50104421, 53787336, 57321033, 80484291, 81054984, 85208924, 90341410, 103122975, 103183384, 104298785, 117562347, 124749645, 124879478, 124879479, 124879480, 126407200, 126730181, 129596750, 135066550, 135649828, 137005038, 139296926, 162908950, 179235696, 198944795, 204422531, 224826810, 228766706, 241134527
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ChEBI ID |
CHEBI:48292
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References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4). | |||
REF 2 | Agonist activity of antimigraine drugs at recombinant human 5-HT1A receptors: potential implications for prophylactic and acute therapy. Naunyn Schmiedebergs Arch Pharmacol. 1997 Jun;355(6):682-8. | |||
REF 3 | Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):3020-4. | |||
REF 4 | Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor. Mol Pharmacol. 1991 Aug;40(2):143-8. | |||
REF 5 | Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor. Eur J Pharmacol. 2004 Jan 26;484(2-3):127-39. | |||
REF 6 | Cloning and characterization of the guinea pig 5-HT1F receptor subtype: a comparison of the pharmacological profile to the human species homolog. Neuropharmacology. 1997 Apr-May;36(4-5):569-76. | |||
REF 7 | Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. Naunyn Schmiedebergs Arch Pharmacol. 2004 Aug;370(2):114-23. | |||
REF 8 | Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor. Mol Pharmacol. 1993 Mar;43(3):419-26. | |||
REF 9 | Agonist high and low affinity state ratios predict drug intrinsic activity and a revised ternary complex mechanism at serotonin 5-HT(2A) and 5-HT(2C) receptors. Synapse. 2000 Feb;35(2):144-50. | |||
REF 10 | Expression of functional mouse 5-HT5A serotonin receptor in the methylotrophic yeast Pichia pastoris: pharmacological characterization and localization. FEBS Lett. 1995 Dec 27;377(3):451-6. | |||
REF 11 | Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. J Neurochem. 1996 Jan;66(1):47-56. | |||
REF 12 | Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. Mol Pharmacol. 1993 Aug;44(2):229-36. |
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