| Target and Pathway |
Top |
| Target(s) |
Epidermal growth factor receptor (EGFR) |
Target Info
|
Inhibitor |
[2] |
| Erbb2 tyrosine kinase receptor (HER2) |
Target Info
|
Inhibitor |
[2] |
| Erbb4 tyrosine kinase receptor (Erbb-4) |
Target Info
|
Inhibitor |
[2] |
| Fyn tyrosine protein kinase (FYN) |
Target Info
|
Inhibitor |
[3] |
| LCK tyrosine protein kinase (LCK) |
Target Info
|
Inhibitor |
[2] |
| Tyrosine-protein kinase Lyn (JTK8) |
Target Info
|
Inhibitor |
[2] |
| Vascular endothelial growth factor receptor 3 (FLT-4) |
Target Info
|
Inhibitor |
[2] |
| Yes tyrosine kinase (YES) |
Target Info
|
Inhibitor |
[2] |
|
KEGG Pathway
|
Chemokine signaling pathway
|
|
NF-kappa B signaling pathway
|
|
Platelet activation
|
|
B cell receptor signaling pathway
|
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Fc epsilon RI signaling pathway
|
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Fc gamma R-mediated phagocytosis
|
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Long-term depression
|
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Epithelial cell signaling in Helicobacter pylori infection
|
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Epstein-Barr virus infection
|
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Viral carcinogenesis
|
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MAPK signaling pathway
|
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ErbB signaling pathway
|
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Ras signaling pathway
|
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Rap1 signaling pathway
|
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Calcium signaling pathway
|
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Cytokine-cytokine receptor interaction
|
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HIF-1 signaling pathway
|
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FoxO signaling pathway
|
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Endocytosis
|
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PI3K-Akt signaling pathway
|
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Dorso-ventral axis formation
|
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Focal adhesion
|
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Adherens junction
|
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Gap junction
|
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Regulation of actin cytoskeleton
|
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GnRH signaling pathway
|
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Estrogen signaling pathway
|
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Oxytocin signaling pathway
|
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Hepatitis C
|
|
Pathways in cancer
|
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Proteoglycans in cancer
|
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MicroRNAs in cancer
|
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Pancreatic cancer
|
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Endometrial cancer
|
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Glioma
|
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Prostate cancer
|
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Melanoma
|
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Bladder cancer
|
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Non-small cell lung cancer
|
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Central carbon metabolism in cancer
|
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Choline metabolism in cancer
|
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Sphingolipid signaling pathway
|
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Axon guidance
|
|
Osteoclast differentiation
|
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Natural killer cell mediated cytotoxicity
|
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T cell receptor signaling pathway
|
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Cholinergic synapse
|
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Prion diseases
|
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Pathogenic Escherichia coli infection
|
|
Measles
|
|
Viral myocarditis
|
|
HTLV-I infection
|
|
Primary immunodeficiency
|
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Tight junction
|
|
NetPath Pathway
|
IL2 Signaling Pathway
|
|
IL4 Signaling Pathway
|
|
EGFR1 Signaling Pathway
|
|
TNFalpha Signaling Pathway
|
|
TSH Signaling Pathway
|
|
TGF_beta_Receptor Signaling Pathway
|
|
TCR Signaling Pathway
|
|
IL5 Signaling Pathway
|
|
Panther Pathway
|
B cell activation
|
|
Parkinson disease
|
|
CCKR signaling map ST
|
|
Cadherin signaling pathway
|
|
EGF receptor signaling pathway
|
|
Axon guidance mediated by semaphorins
|
|
Integrin signalling pathway
|
|
T cell activation
|
|
Alzheimer disease-presenilin pathway
|
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Pathwhiz Pathway
|
Fc Epsilon Receptor I Signaling in Mast Cells
|
|
Phosphatidylinositol Phosphate Metabolism
|
|
Pathway Interaction Database
|
Fc-epsilon receptor I signaling in mast cells
|
|
BCR signaling pathway
|
|
LPA receptor mediated events
|
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GMCSF-mediated signaling events
|
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Glypican 1 network
|
|
Signaling events mediated by PTP1B
|
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Regulation of p38-alpha and p38-beta
|
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Thromboxane A2 receptor signaling
|
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CXCR4-mediated signaling events
|
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IL5-mediated signaling events
|
|
Class I PI3K signaling events
|
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amb2 Integrin signaling
|
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EPHA forward signaling
|
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PDGFR-beta signaling pathway
|
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IL8- and CXCR2-mediated signaling events
|
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Signaling events mediated by Stem cell factor receptor (c-Kit)
|
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EPO signaling pathway
|
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IL8- and CXCR1-mediated signaling events
|
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Ephrin B reverse signaling
|
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Alpha-synuclein signaling
|
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Arf6 signaling events
|
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Signaling events mediated by TCPTP
|
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SHP2 signaling
|
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Regulation of Telomerase
|
|
EGF receptor (ErbB1) signaling pathway
|
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EGFR-dependent Endothelin signaling events
|
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Posttranslational regulation of adherens junction stability and dissassembly
|
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Direct p53 effectors
|
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ErbB1 downstream signaling
|
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Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
|
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E-cadherin signaling in keratinocytes
|
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ErbB receptor signaling network
|
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Internalization of ErbB1
|
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Stabilization and expansion of the E-cadherin adherens junction
|
|
a6b1 and a6b4 Integrin signaling
|
|
Syndecan-3-mediated signaling events
|
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VEGF and VEGFR signaling network
|
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VEGFR3 signaling in lymphatic endothelium
|
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ErbB4 signaling events
|
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TCR signaling in naï
|
|
|
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Ephrin A reverse signaling
|
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Reelin signaling pathway
|
|
TCR signaling in naï
|
|
|
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Angiopoietin receptor Tie2-mediated signaling
|
|
Netrin-mediated signaling events
|
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IL2-mediated signaling events
|
|
Nephrin/Neph1 signaling in the kidney podocyte
|
|
Signaling events mediated by VEGFR1 and VEGFR2
|
|
Signaling events mediated by focal adhesion kinase
|
|
ErbB2/ErbB3 signaling events
|
|
Validated targets of C-MYC transcriptional repression
|
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Atypical NF-kappaB pathway
|
|
IL12-mediated signaling events
|
|
IL2 signaling events mediated by PI3K
|
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IL2 signaling events mediated by STAT5
|
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Noncanonical Wnt signaling pathway
|
|
CDC42 signaling events
|
|
Reactome
|
GPVI-mediated activation cascade
|
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Regulation of KIT signaling
|
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Cell surface interactions at the vascular wall
|
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FCGR activation
|
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PECAM1 interactions
|
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Fc epsilon receptor (FCERI) signaling
|
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EPH-Ephrin signaling
|
|
Role of LAT2/NTAL/LAB on calcium mobilization
|
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FCERI mediated MAPK activation
|
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FCERI mediated Ca+2 mobilization
|
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FCERI mediated NF-kB activation
|
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CD28 co-stimulation
|
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CTLA4 inhibitory signaling
|
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EPHB-mediated forward signaling
|
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EPHA-mediated growth cone collapse
|
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EPH-ephrin mediated repulsion of cells
|
|
Dectin-2 family
|
|
CD209 (DC-SIGN) signaling
|
|
Platelet Adhesion to exposed collagen
|
|
Regulation of signaling by CBL
|
|
Growth hormone receptor signaling
|
|
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
|
|
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
|
|
SHC1 events in ERBB2 signaling
|
|
PLCG1 events in ERBB2 signaling
|
|
PIP3 activates AKT signaling
|
|
GRB2 events in EGFR signaling
|
|
GAB1 signalosome
|
|
SHC1 events in EGFR signaling
|
|
EGFR downregulation
|
|
GRB2 events in ERBB2 signaling
|
|
PI3K events in ERBB2 signaling
|
|
EGFR Transactivation by Gastrin
|
|
Constitutive Signaling by Aberrant PI3K in Cancer
|
|
Constitutive Signaling by EGFRvIII
|
|
RAF/MAP kinase cascade
|
|
VEGF binds to VEGFR leading to receptor dimerization
|
|
DAP12 signaling
|
|
Nephrin interactions
|
|
NCAM signaling for neurite out-growth
|
|
CD28 dependent PI3K/Akt signaling
|
|
CD28 dependent Vav1 pathway
|
|
CRMPs in Sema3A signaling
|
|
DCC mediated attractive signaling
|
|
Netrin mediated repulsion signals
|
|
VEGFA-VEGFR2 Pathway
|
|
Sema4D induced cell migration and growth-cone collapse
|
|
Phosphorylation of CD3 and TCR zeta chains
|
|
Translocation of ZAP-70 to Immunological synapse
|
|
Generation of second messenger molecules
|
|
PD-1 signaling
|
|
Interleukin-2 signaling
|
|
WikiPathways
|
Kit receptor signaling pathway
|
|
IL-3 Signaling Pathway
|
|
Fc epsilon receptor (FCERI) signaling
|
|
Signaling by the B Cell Receptor (BCR)
|
|
Signaling by SCF-KIT
|
|
Growth hormone receptor signaling
|
|
B Cell Receptor Signaling Pathway
|
|
TSLP Signaling Pathway
|
|
RANKL/RANK Signaling Pathway
|
|
Platelet Adhesion to exposed collagen
|
|
GPVI-mediated activation cascade
|
|
Costimulation by the CD28 family
|
|
Cell surface interactions at the vascular wall
|
|
IL-5 Signaling Pathway
|
|
ErbB Signaling Pathway
|
|
Regulation of Actin Cytoskeleton
|
|
EGF/EGFR Signaling Pathway
|
|
MAPK Signaling Pathway
|
|
Focal Adhesion
|
|
Aryl Hydrocarbon Receptor Pathway
|
|
Extracellular vesicle-mediated signaling in recipient cells
|
|
TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer
|
|
Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
|
|
Bladder Cancer
|
|
Hair Follicle Development: Induction (Part 1 of 3)
|
|
Signaling by ERBB4
|
|
Signaling by ERBB2
|
|
Gastrin-CREB signalling pathway via PKC and MAPK
|
|
PIP3 activates AKT signaling
|
|
Nanoparticle-mediated activation of receptor signaling
|
|
Aryl Hydrocarbon Receptor
|
|
Spinal Cord Injury
|
|
Integrated Pancreatic Cancer Pathway
|
|
Gastric cancer network 2
|
|
AGE/RAGE pathway
|
|
Signaling Pathways in Glioblastoma
|
|
Arylhydrocarbon receptor (AhR) signaling pathway
|
|
miR-targeted genes in muscle cell - TarBase
|
|
miR-targeted genes in lymphocytes - TarBase
|
|
miR-targeted genes in epithelium - TarBase
|
|
Integrated Breast Cancer Pathway
|
|
Signaling by EGFR
|
|
L1CAM interactions
|
|
Signaling by VEGF
|
|
TCR Signaling Pathway
|
|
Interferon type I signaling pathways
|
|
IL-2 Signaling Pathway
|
|
Ectoderm Differentiation
|
|
DAP12 interactions
|
|
Host Interactions of HIV factors
|
|
T-Cell Receptor and Co-stimulatory Signaling
|
|
Primary Focal Segmental Glomerulosclerosis FSGS
|
|
BDNF signaling pathway
|
|
Interleukin-11 Signaling Pathway
|
|
Pathogenic Escherichia coli infection
|
|
IL-7 Signaling Pathway
|
|
Leptin signaling pathway
|
|
Semaphorin interactions
|
|
Netrin-1 signaling
|
|
Nephrin interactions
|
|
NCAM signaling for neurite out-growth
|
|
Integrin-mediated Cell Adhesion
|
|
DNA Damage Response (only ATM dependent)
|
|
Notch Signaling Pathway
|
|
Inflammatory Response Pathway
|
|
TCR signaling
|
|
EV release from cardiac cells and their functional effects
|
