Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CCKBR --- CCKAR | N-tert-Butyl-2-{(3R,5R)-3-[3-(3-chloro-phenyl)-ureido]-5-isopropyl-8-methyl-2-oxo-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-acetamide | Drug Info |
| CCKBR --- CCKAR | 4-[3-(4-Chloro-phenyl)-ureido]-4-dipentylcarbamoyl-butyric acid ethyl ester: (0.1chloroform) | Drug Info |
| CCKBR --- CCKAR | 3-(3-{5-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-5-[1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-carboxy-ethylcarbamoyl]-pentyl}-ureido)-benzoic acid methyl ester | Drug Info |
| CCKBR --- CCKAR | (S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-[(S)-2-[(S)-3-1H-indol-3-yl-2-(3-phenyl-ureido)-propionylamino]-6-(3-o-tolyl-ureido)-hexanoylamino]-N-methyl-succinamic acid | Drug Info |
| CD221 --- JNK1 | 2-fluoro-6-(2-(2-methoxy-5-(1-propylpiperidin-4-yloxy)phenylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzamide | Drug Info |
| CDK1 --- AuroraA | N-(4-(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylamino)phenyl)-N-(3-morpholinopropyl)methanesulfonamide | Drug Info |
| CDK1 --- CDK2 | (3-Chloro-phenyl)-(6-cyclohexylmethoxy-9H-purin-2-yl)-amine | Drug Info |
| CDK1 --- CDK4 | 4-amino-6-bromo-7-(b-L-xylofuranosyl)pyrrolo[2,3-d]pyrimidine-5-carboxamide | Drug Info |
| CDK1 --- GSK3 | N-(9-bromo-7,12-dihydro-benzo[2,3]azepino[4,5-b]indol-6-yl)-hydroxylamine | Drug Info |
| CDK1 --- GSK3 | 2-Bromo-9-nitro-5,12-dihydro-7H-benzo[2,3]azepino[4,5-b]indol-6-one | Drug Info |
| CDK1 --- VEGFR | 5-chloro-4-(1H-indol-6-yl)-N-(4-(2-(pyrrolidin-1-yl)ethyl)phenyl)pyrimidin-2-amine | Drug Info |
| CDK2 --- AKT | (R)-4-(3-(isoquinolin-6-yl)isoxazol-5-yl)-1-(4-(trifluoromethyl)phenyl)butan-2-amine | Drug Info |
| CDK2 --- AuroraA | 4-methyl-N-(5-(quinoline-8-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)benzamide | Drug Info |
| CDK2 --- AuroraA | N-(2,6-Diethylphenyl)-8-({2-methoxy-4-[(4-methyl-1,4-diazepan-1-yl)carbonyl]phenyl}amino)-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- CDK1 | (Z)-4-(2-(4-((E)-4-hydroxystyryl)-2-oxoindolin-3-ylidene)hydrazinyl)benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | (R)-2-amino-N-(4-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-ylamino)phenylsulfonyl)-3-hydroxypropanamide | Drug Info |
| CDK2 --- CDK1 | GW300657X | Drug Info |
| CDK2 --- CDK1 | 4-[(7-Oxo-6,7-dihydro-thiazolo[5,4-e]indol-8-ylidenemethyl)-amino]-N-phenyl-benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | 2,4,5-trichloro-N-(3-(trifluoromethyl)phenyl)benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | 3-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | 3-(6-Cyclopentylamino-9-isopropyl-9H-purin-2-ylamino)-propan-1-ol | Drug Info |
| CDK2 --- CDK4 | GW801372X | Drug Info |
| CDK2 --- CDK4 | CHEMBL101468 | Drug Info |
| CDK2 --- CDK4 | GW778894X | Drug Info |
| CDK2 --- CDK4 | [4-(6-Methoxy-pyrazolo[1,5-b]pyridazin-3-yl)-pyrimidin-2-yl]-(4-nitro-phenyl)-amine | Drug Info |
| CDK2 --- Cyclin E | 5-Benzenesulfonyl-4-butoxy-1H-pyrazolo[3,4-b]pyridine | Drug Info |
| CDK2 --- Cyclin E | tert-Butyl-(2-trichloromethyl-quinazolin-4-yl)-amine | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((5-phenylthiophen-3-yl)methyl)-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-N6-((5-(furan-2-yl)thiophen-2-yl)methyl)-9-isopropyl-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | N2-(3-aminocyclohexyl)-N6-(biphenyl-4-ylmethyl)-9-isopropyl-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | CHEMBL1197552 | Drug Info |
| CDK2 --- Cyclin E | 4-Butoxy-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethylamide | Drug Info |
| CDK2 --- GSK3 | N*5*-(4-Amino-cyclohexyl)-3-chloro-N*7*-[4-(thiophene-2-sulfonyl)-phenyl]-pyrazolo[1,5-a]pyrimidine-5,7-diamine | Drug Info |
| CAII --- CAI | 3-Bromo-4-(3-pentafluorophenyl-ureido)-benzenesulfonamide | Drug Info |
| CDK4 --- Cyclin E | N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)-4-oxo-2,4-dihydroindeno[1,2-c]pyrazol-5-yl]-2,2-dimethylhydrazinecarboxamide | Drug Info |
| CAII --- CAI | 4-Chloro-3-sulfamoyl-N-(4-sulfamoyl-benzyl)-benzamide | Drug Info |
| Ckit --- BRaf | 4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carbamoyl)phenylamino)methyl)-N-(3-morpholinopropyl)picolinamide | Drug Info |
| CAII --- CAI | (S)-2-(4-Chloro-3-sulfamoyl-benzoylamino)-pentanedioic acid | Drug Info |
| Cmet --- Ckit | N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenylcarbamothioyl)-2-phenylacetamide | Drug Info |
| CAII --- CAI | 1-(4-Aminophenyl)-4-benzoyl-5-phenyl-N-(5-sulfamoyl-1,3,4-thiadiazole-2-yl)-1H-pyrazole-3-carboxamide | Drug Info |
| COX2 --- 5LOX | 2,6-Dimethyl-4-(2-naphthalen-1-yl-vinyl)-phenol | Drug Info |
| CAII --- CAI | 4-(4-phenyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide | Drug Info |
| COX2 --- 5LOX | 2-Methoxy-6-propyl-4-(2-thiophen-2-yl-vinyl)-phenol | Drug Info |
| CAII --- CAI | 2,6-Diisopropyl-4-phenyl-1-{[4-(3-sulfamoyl-phenylsulfamoyl)-phenylcarbamoyl]-methyl}-pyridinium; perchlorate | Drug Info |
| CSrc --- CABL | (S)-1-(2-chloro-2-phenylethyl)-6-(2-morpholinoethylthio)-N-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| CAII --- CAI | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-Heptadecafluoro-nonanoic acid [2-(4-sulfamoyl-phenyl)-ethyl]-amide | Drug Info |
| CSrc --- CABL | N-(5-(4-bromobenzylthio)-1,3,4-thiadiazol-2-yl)-4-chlorobenzamide | Drug Info |
| CAII --- CAI | {[2-(Bis-carboxymethyl-amino)-ethyl]-[(4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-acetic acid | Drug Info |
| CSrc --- CABL | N-(5-(3-fluorobenzylthio)-1,3,4-thiadiazol-2-yl)-2-chlorobenzamide | Drug Info |
| CAII --- CAI | 4-(4-p-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide | Drug Info |
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