Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(4-hydroxy-phenyl)-propionylamino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid; hydrate | Drug Info |
| CCKBR --- CCKAR | Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-NMeNle-D-Trp-Boc | Drug Info |
| CCKBR --- CCKAR | CCK7 analogue | Drug Info |
| CCKBR --- CCKAR | CCK7 analogue | Drug Info |
| CCKBR --- CCKAR | (S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-[(S)-2-[(S)-3-1H-indol-3-yl-2-(2,2,2-trifluoro-acetylamino)-propionylamino]-6-(3-o-tolyl-ureido)-hexanoylamino]-N-methyl-succinamic acid | Drug Info |
| CCKBR --- CCKAR | {2-(1H-Indol-3-yl)-1-methyl-1-[2-(4-nitro-phenyl)-ethylcarbamoyl]-ethyl}-carbamic acid adamantan-2-yl ester | Drug Info |
| CCKBR --- CCKAR | CCK7 analogue | Drug Info |
| CCKBR --- CCKAR | N-{(S)-1-[(S)-1-{1-[(S)-((S)-1-Carbamoyl-2-phenyl-ethyl)-methyl-carbamoyl]-2-carboxy-ethylcarbamoyl}-5-(3-o-tolyl-ureido)-pentylcarbamoyl]-2-1H-indol-3-yl-ethyl}-phthalamic acid | Drug Info |
| CCKBR --- CCKAR | D-Tyr-Gly-[(Nle28,31,Bpa29)CCK-26-33] | Drug Info |
| CCKBR --- CCKAR | (S)-N-[5-(2-Fluoro-phenyl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-2-iodo-benzamide | Drug Info |
| CD135 --- Ckit | N3-(2-methoxyphenyl)-1-(pyridin-2-yl)-1H-1,2,4-triazole-3,5-diamine | Drug Info |
| CD221 --- JNK1 | 2-fluoro-6-(2-(6-methoxy-1-(2-(piperidin-1-yl)acetyl)-1,2,3,4-tetrahydroquinolin-7-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzamide | Drug Info |
| CDK1 --- CDK2 | GW301784X | Drug Info |
| CDK1 --- CDK2 | 2-oxo-3-[(4-sulfamoyl-phenyl)-hydrazono]-2,3-dihydro-1H-indole-5-sulfonic acid amide | Drug Info |
| CDK1 --- GSK3 | SID515252 | Drug Info |
| CDK1 --- GSK3 | Dimethyl-sulfamic acid 4-(7-methyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)-phenyl ester | Drug Info |
| CDK1 --- GSK3 | 2-Iodo-5,12-dihydro-7H-benzo[2,3]azepino[4,5-b]indol-6-one | Drug Info |
| CDK1 --- VEGFR | 5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1H-indol-7-yl)pyrimidin-2-amine | Drug Info |
| CDK2 --- AKT | (S)-N1-(2-(isoquinolin-6-yl)thiazol-5-yl)-3-(4-(trifluoromethyl)phenyl)propane-1,2-diamine | Drug Info |
| CDK2 --- AuroraA | (S)-4-{2-(2-Fluorophenylamino)-5-methylpyrimidin-4-yl}-N-{1-phenyl-2-hydroxyethyl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- AuroraA | N,1-Dimethyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- CDK1 | 4-{N'-[7-oxo-6,7-dihydro-thiazolo[5,4-e]indol-(8Z)-ylidene]-hydrazino}-benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | DNDI1417312 | Drug Info |
| CDK2 --- CDK1 | 2-oxo-3-[1-(4-sulfamoyl-phenylamino)-meth-(Z)-ylidene]-2,3-dihydro-1H-indole-5-carboxylic acid | Drug Info |
| CDK2 --- CDK1 | 2-amino-N-(4-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-ylamino)phenylsulfonyl)acetamide | Drug Info |
| CDK2 --- CDK1 | (Z)-4-(2-(2-oxo-4-(1H-pyrazol-3-yl)indolin-3-ylidene)hydrazinyl)benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | 4-[5-(4-Amino-phenyl)-2H-pyrazol-3-ylamino]-benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | (Z)-4-((4-(hydroxymethyl)-2-oxoindolin-3-ylidene)methylamino)benzenesulfonamide | Drug Info |
| CDK2 --- CDK4 | 1-(dimethylamino)-3-(4-(4-(6-morpholinopyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-ylamino)phenoxy)propan-2-ol | Drug Info |
| CDK2 --- CDK4 | CHEMBL101119 | Drug Info |
| CDK2 --- CDK4 | N-cyclopropyl-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine | Drug Info |
| CDK2 --- CSrc | (2-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)thiazol-4-yl)methanol | Drug Info |
| CDK2 --- Cyclin E | [6-(3-Amino-phenyl)-2-trifluoromethyl-quinazolin-4-yl]-tert-butyl-amine | Drug Info |
| CDK2 --- Cyclin E | 2-[2-[Bis-(2-hydroxy-ethyl)-amino]-6-(4-methoxy-benzylamino)-purin-9-yl]-ethanol | Drug Info |
| CDK2 --- Cyclin E | 2-[[6-(4-Bromo-phenylamino)-9-isopropyl-9H-purin-2-yl]-(2-hydroxy-ethyl)-amino]-ethanol | Drug Info |
| CDK2 --- Cyclin E | N2-(trans-4-aminocyclohexyl)-9-isopropyl-N6-((3'-methylbiphenyl-4-yl)methyl)-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | tert-Butyl-[6-(3-methoxy-phenyl)-2-trifluoromethyl-quinazolin-4-yl]-amine | Drug Info |
| CDK2 --- Cyclin E | (E)-N'-benzylidene-2-(5-((2-(2-chloroacetamido)thiazol-4-yl)methyl)-4-(4-chlorobenzamido)-4H-1,2,4-triazol-3-ylthio)acetohydrazide | Drug Info |
| CDK2 --- Cyclin E | 3-Methylsulfanyl-6-methylsulfanylmethyl-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
| CDK2 --- JNK1 | 4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-N-(4-methylpiperidin-1-yl)piperidine-1-carboxamide | Drug Info |
| CAII --- CAI | 2,4,6-trimethyl-1-(3-phenyl-5-sulfamoyl-1H-indole-2-carboxamido)pyridinium perchlorate | Drug Info |
| Chk --- Met | CHEMBL1197529 | Drug Info |
| CAII --- CAI | {Carboxymethyl-[2-(4-sulfamoyl-phenyl)-ethoxycarbonylmethyl]-amino}-acetic acid | Drug Info |
| Ckit --- BRaf | 2-(pyridin-4-ylmethylamino)-N-(2,2,3,3-tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzamide | Drug Info |
| CAII --- CAI | (R)-4-((8S,10S,12S,14R,15R,17S)-3,12-Di(R)-hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid (2-bromo-4-sulfamoyl-phenyl)-amide | Drug Info |
| COX2 --- 5LOX | 1-(4-Bromo-phenyl)-5-nitro-1lambda(4)-benzo[1,3,2]dithiazole 3,3-dioxide | Drug Info |
| CAII --- CAI | 4-[(Heptadecafluorooctane-1-sulfonylamino)-methyl]-benzenesulfonamide | Drug Info |
| COX2 --- 5LOX | 1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-2-cyclopropyl-ethanone | Drug Info |
| CAII --- CAI | 4-((5S,6S,7S,8R,11S,15R,17S)-3,7-Dihydroxy-10-methyl-13-(R)-methyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid (2,3-dichloro-4,6-disulfamoyl-phenyl)-amide | Drug Info |
| COX2 --- HRH1 | 11-{2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-ethylsulfanyl}-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid | Drug Info |
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