Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CAII --- CAI | [(S)-3-(3H-Imidazol-4-yl)-2-(4-sulfamoyl-benzoylamino)-propionylamino]-acetic acid | Drug Info |
| EGFR3 --- HER2 | 4-[(3-chlorophenyl)amino]-6-(methylamino)quinazoline | Drug Info |
| CAII --- CAI | 5-(Heptadecafluorooctane-1-sulfonylimino)-4-methyl-4,5-dihydro-[1,3,4]thiadiazole-2-sulfonic acid amide | Drug Info |
| CAII --- CAI | {{2-[Carboxymethyl-(2-{carboxymethyl-[(5-chloro-2,4-disulfamoyl-phenylcarbamoyl)-methyl]-amino}-ethyl)-amino]-ethyl}-[(5-chloro-2,4-disulfamoyl-phenylcarbamoyl)-methyl]-amino}-acetic acid | Drug Info |
| CAII --- CAI | N-(2,3-Dichloro-4,6-disulfamoyl-phenyl)-2-(N-methyl-guanidino)-acetamide | Drug Info |
| CAII --- CAI | 3-(1H-Imidazol-4-yl)-2-{3-[3-(4-sulfamoyl-phenyl)-thioureido]-propionylamino}-propionic acid | Drug Info |
| CAII --- CAI | {{2-[2-(2-{Carboxymethyl-[(4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-ethoxy)-ethoxy]-ethyl}-[(4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-acetic acid | Drug Info |
| CAII --- CAI | 6-Pentafluorobenzenesulfonylamino-benzothiazole-2-sulfonic acid amide | Drug Info |
| CAII --- CAI | (S)-2-[3-(4-Sulfamoyl-phenyl)-thioureido]-succinamic acid methylcarbamoylmethyl with resin | Drug Info |
| CAII --- CAI | 6-(2-Sulfamoyl-benzothiazol-6-ylcarbamoyl)-pyridine-2-carboxylic acid | Drug Info |
| CAII --- CAIX | 4-(bis(4-methylpiperidin-1-yl)amino)-N-(4-sulfamoylphenyl)butanamide | Drug Info |
| CAIX --- CAXII | 2'-(2-oxo-2H-chromen-7-yloxy)ethyl4''-methylbenzenesulfonate | Drug Info |
| CALM2 --- Cathepsin B | (R)-1-(naphthalen-1-ylsulfonyl)-N-((R,S)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide | Drug Info |
| CALM2 --- Cathepsin B | (R)-1-(4-methoxyphenylsulfonyl)-N-((R,S)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide | Drug Info |
| CALM2 --- Cathepsin B | [1-(1-Benzylaminooxalyl-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- Cathepsin B | (R)-N-(1-cyano-cyclopropyl)-3-methanesulfonyl-2-[(S)-2,2,2-trifluoro-1-(4'-fluoro-biphenyl-4-yl)-ethylamino]-propionamide | Drug Info |
| Cathepsin K --- MEP | N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]benzoyl}-leucyl-glycine-nitrile | Drug Info |
| Cathepsin K --- MEP | N-((S)-1-((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)-3-(1-methylcyclohexyl)-1-oxopropan-2-yl)furan-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | [1-(3-Methoxy-1-methyl-2-oxo-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | 2-(cyclohexylmethyl)-4-morpholino-4-oxo-N-(1-(4-(trifluoromethoxy)phenylamino)propan-2-yl)butanamide | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-cyclohexylamino-pyrimidine-5-carboxylic acid [2-(3-methoxyphenyl)-ethyl]-amide | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-(2,2-dimethyl-propylamino)-pyrimidine-5-carboxylic acid [2-(3-methoxy-phenyl)-ethyl]-amide | Drug Info |
| Cathepsin K --- MEP | N-(tert-butoxycarbonyl)-phenylalanyl-glycine-nitrile | Drug Info |
| Cathepsin K --- MEP | N-[1-(2S-Ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-3-fluoro-4-methanesulfonylamino-benzamide | Drug Info |
| CCKBR --- CCKAR | {1-[5-(2-Fluoro-phenyl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester | Drug Info |
| CCKBR --- CCKAR | (S)-4-Bromo-N-[5-(2-fluoro-phenyl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-benzamide | Drug Info |
| CCKBR --- CCKAR | N-(1-Carbamoyl-2-phenyl-ethyl)-3-{[(3R,13R)-3-(1H-indol-3-ylmethyl)-3-methyl-2,5,7-trioxo-1,4,8triaza-cyclotridecane-13-carbonyl]-amino}-succinamic acid | Drug Info |
| CCKBR --- CCKAR | Phenyl-carbamic acid (R)-3-(4-benzoyl-piperidin-1-yl)-3-oxo-2-(3-m-tolyl-ureido)-propyl ester | Drug Info |
| CCKBR --- CCKAR | (S)-3-{(S)-2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[(E)-3-(4-hydroxy-phenyl)-acryloylamino]-hexanoylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-N-methyl-succinamic acid | Drug Info |
| CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(3-sulfooxy-phenyl)-propionylamino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid; NH40H.hydrate | Drug Info |
| CCKBR --- CCKAR | H-Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-Nle-D-Trp-1-Adoc | Drug Info |
| CCKBR --- CCKAR | CHEMBL1172251 | Drug Info |
| CCKBR --- CCKAR | 3-{(S)-2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(2-chloro-phenyl)-ureido]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid | Drug Info |
| CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(2,4-dichloro-phenyl)-acryloylamino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid; hydrate | Drug Info |
| CCKBR --- CCKAR | (S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-[(S)-2-[(S)-3-(1H-indol-3-yl)-2-methoxycarbonylamino-propionylamino]-6-(3-o-tolyl-ureido)-hexanoylamino]-N-methyl-succinamic acid | Drug Info |
| CD221 --- JNK1 | GSK1751853A | Drug Info |
| CDK1 --- AuroraA | N-(4-(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylamino)phenyl)-N-(3-hydroxypropyl)methanesulfonamide | Drug Info |
| CDK1 --- CDK2 | [3-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-phenyl]-methanol | Drug Info |
| CDK1 --- CDK2 | (Z)-4-((5-(3-methylbutanoyl)-2-oxoindolin-3-ylidene)methylamino)benzenesulfonamide | Drug Info |
| CDK1 --- GSK3 | 9-Bromo-3-hydroxy-5,12-dihydro-7H-benzo[2,3]azepino[4,5-b]indol-6-one | Drug Info |
| CDK1 --- GSK3 | 8-Chloro-6,11-dihydro-thieno[3',2':2,3]azepino[4,5-b]indol-5(4H)-one | Drug Info |
| CDK1 --- GSK3 | 2-(2-Oxo-propyl)-9-trifluoromethyl-5,12-dihydro-7H-benzo[2,3]azepino[4,5-b]indol-6-one | Drug Info |
| CDK2 --- AKT | GSK269962A | Drug Info |
| CDK2 --- AuroraA | 8-(Phenylamino)-1-[2-(piperidin-1-yl)ethyl]-4,5-dihydro-1Hpyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | 1-Methyl-8-{[3-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- Beta PDGFR | 1-(5-Chloro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-6,7-dihydro-2H-pyrano[3,4-c]pyrrol-4-one | Drug Info |
| CDK2 --- CDK1 | (Z)-4-(2-(4-ethoxy-2-oxoindolin-3-ylidene)hydrazinyl)benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | 6-[(Cyclohexylmethyl)oxy]purine | Drug Info |
| CDK2 --- CDK1 | SID537003 | Drug Info |
| CDK2 --- CDK1 | (Z)-4-(2-(4-isopropyl-2-oxoindolin-3-ylidene)hydrazinyl)benzenesulfonamide | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.