Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CAII --- CAIX | 2-(4-chlorobenzyloxyamino)-N-hydroxyhexanamide | Drug Info |
| CAII --- CAXII | Catechol | Drug Info |
| CAIX --- CAXII | SID144213440 | Drug Info |
| CALM2 --- Cathepsin B | (R)-1-(4-chlorophenylsulfonyl)-N-((R,S)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide | Drug Info |
| CALM2 --- Cathepsin B | (1-{1-[2-(3-Methoxy-phenyl)-ethylaminooxalyl]-propylcarbamoyl}-3-methyl-butyl)-carbamic acid benzyl ester | Drug Info |
| CALM2 --- Cathepsin B | {3-Methyl-1-[1-(pyridin-3-ylmethyl)-aminooxalyl]-propylcarbamoyl}-butyl)-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- Cathepsin B | N-Cyanomethyl-3-cyclopropyl-2-[4'-(4-methyl-piperazin-1-yl)-biphenyl-3-yl]-propionamide | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-benzyl-cyclopentylmethyl ester | Drug Info |
| Cathepsin K --- MEP | 4-Benzenesulfonylamino-3-chloro-N-[1-(2S-ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-benzamide | Drug Info |
| Cathepsin K --- MEP | 1-(2-Chloro-phenyl)-1H-[1,2,4]triazole-3-carboxylic acid {1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-amide | Drug Info |
| Cathepsin K --- MEP | 4-Methoxy-N-{1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-benzamide | Drug Info |
| Cathepsin K --- MEP | (S)-2-(7-chlorobenzo[d]oxazol-2-ylamino)-3-cyclohexyl-N-((S)-1-(4-(methylsulfonyl)phenylamino)propan-2-yl)propanamide | Drug Info |
| Cathepsin K --- MEP | (S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanesulfonyl-biphenyl-4-yl)-ethylamino]-pentanoic acid (cyano-dicyclopropyl-methyl)-amide | Drug Info |
| Cathepsin K --- MEP | (S)-2-(7-chlorobenzo[d]oxazol-2-ylamino)-3-cyclohexyl-N-((S)-1-(5-fluoro-3,3-dimethylindolin-1-yl)propan-2-yl)propanamide | Drug Info |
| Cathepsin K --- MEP | 9-Cyclopentyl-6-{2-[3-(4-methyl-piperazin-1-yl)-propoxy]-phenylamino}-9H-purine-2-carbonitrile | Drug Info |
| CCKBR --- CCKAR | (S)-2-(2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-4-chlorobenzamido)-3-(3-bromo-4-chlorophenyl)propanoic acid | Drug Info |
| CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[(6-hydroxy-naphthalene-2-carbonyl)-amino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-N-methyl-succinamic acid; hydrate | Drug Info |
| CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(4-dimethylamino-phenyl)-acryloylamino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid; hydrate | Drug Info |
| CCKBR --- CCKAR | (R)-2-(2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-4-chlorobenzamido)-3-phenylpropanoic acid | Drug Info |
| CCKBR --- CCKAR | (S)-2-[3-(3-Methoxy-phenyl)-ureido]-5-oxo-5-pyrrolidin-1-yl-pentanoic acid dipentylamide | Drug Info |
| CCKBR --- CCKAR | N-tert-Butyl-2-{(3R,5R)-8-methyl-2-oxo-5-phenyl-3-[3-(3-phenylmethanesulfonylaminocarbonyl-phenyl)-ureido]-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-acetamide | Drug Info |
| CCKBR --- CCKAR | (3S,6S,9S,15S,18S,21S)-9-((1H-indol-3-yl)methyl)-21-amino-3-((S)-1-amino-1-oxo-3-phenylpropan-2-ylcarbamoyl)-6,15-bis(2-(methylthio)ethyl)-5,8,11,14,17,20-hexaoxo-18-(4-(sulfooxy)benzyl)-4,7,10,13,16,19-hexaazatricosane-1,23-dioic acid | Drug Info |
| CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(4-sulfooxy-phenyl)-propionylamino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid,NH4OH | Drug Info |
| CCKBR --- CCKAR | Boc-Tyr(So3-)-Nle-Gly-Trp-Nle-Asp-psi(CH2NH)-Phe-NH2 | Drug Info |
| CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[2-(4-hydroxy-phenyl)-acetylamino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid; hydrate | Drug Info |
| CCKBR --- CCKAR | 2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-4-chloro-N-(3,4-dichlorophenethyl)benzamide | Drug Info |
| CD221 --- JNK1 | 2-fluoro-6-(2-(5-methoxy-1-(2-(methoxy(methyl)amino)acetyl)indolin-6-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzamide | Drug Info |
| CDK1 --- AuroraA | N-(4-(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylamino)phenyl)-N-(pyridin-4-ylmethyl)methanesulfonamide | Drug Info |
| CDK1 --- CDK2 | K00613a | Drug Info |
| CDK1 --- CDK4 | (2,6-Dichloro-phenyl)-[2-(4-methylsulfanyl-phenylamino)-imidazo[1,2-a]pyridin-6-yl]-methanone | Drug Info |
| CDK1 --- GSK3 | SID527126 | Drug Info |
| CDK1 --- GSK3 | 6-(3,4-Dimethoxy-phenyl)-7-methyl-5H-pyrrolo[2,3-b]pyrazine | Drug Info |
| CDK1 --- VEGFR | 3-{4-[6-(3-Chloro-phenylamino)-pyrazin-2-yl]-pyridin-3-ylamino}-propan-1-ol | Drug Info |
| CDK2 --- AKT | (S)-N1-(5-(3-methyl-1H-indazol-5-yl)-1,3,4-thiadiazol-2-yl)-3-(3-(trifluoromethyl)phenyl)propane-1,2-diamine | Drug Info |
| CDK2 --- AuroraA | 8-(Phenylamino)-1-(2,2,2-trifluoroethyl)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | (S)-4-{2-(2-Methylphenylamino)-5-methylpyrimidin-4-yl}-N-{1-phenyl-2-hydroxyethyl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- CD221 | CHEMBL1809191 | Drug Info |
| CDK2 --- CDK1 | N-Acetyl-4-[(7-oxo-6,7-dihydro-thiazolo[5,4-e]indol-8-ylidenemethyl)-amino]-benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | N-(2-Hydroxy-ethyl)-4-[(7-oxo-6,7-dihydro-thiazolo[5,4-e]indol-8-ylidenemethyl)-amino]-benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | 2-(2-aminopyrimidin-4-yl)-4-morpholinophenol | Drug Info |
| CDK2 --- CDK1 | CHEMBL1187319 | Drug Info |
| CDK2 --- CDK1 | (6-Cyclohexylmethoxy-9H-purin-2-yl)-(4-methoxy-phenyl)-amine | Drug Info |
| CDK2 --- CDK1 | 5-[(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-methyl]-thiophene-2-sulfonic acid amide | Drug Info |
| CDK2 --- CDK4 | CHEMBL485240 | Drug Info |
| CDK2 --- CDK4 | [4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-pyrimidin-2-yl]-[5-(3,3-dimethyl-piperazin-1-yl)-pyridin-2-yl]-amine | Drug Info |
| CDK2 --- CDK4 | 4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)pyrimidin-2-amine | Drug Info |
| CDK2 --- CDK4 | CHEMBL99689 | Drug Info |
| CDK2 --- Cyclin E | N-[5-(2-Hydroxy-4,4-dimethyl-pentylsulfanyl)-thiazol-2-yl]-acetamide | Drug Info |
| CDK2 --- Cyclin E | 6-(3-Hydroxy-propyl)-3-methylsulfanyl-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
| CDK2 --- Cyclin E | 6-(4-Bromo-benzyl)-3-ethyl-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
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