Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CAII --- CAI | Ethyl1-(3-iodophenyl)-5-phenyl-3-(5-sulfamoyl-1,3,4-thiadiazol-2-ylcarbamoyl)-1H-pyrazole-4-carboxylate | Drug Info |
| EGFR --- Src | 3-{2-[3-(2-Carbamoyl-ethyl)-1H-indol-2-yldisulfanyl]-1H-indol-3-yl}-propionamide | Drug Info |
| CAII --- CAI | N-(4-sulfamoylbenzyl)pivalamide | Drug Info |
| EGFR3 --- CSrc | 4-{2-[3-(4-carboxybenzoyl)-1-methyl-1H-2-indolyldisulfanyl]-1-methyl-1H-3-indolylcarbonyl}benzoic acid2 H2O | Drug Info |
| CAII --- CAI | 2,6-Diisopropyl-4-phenyl-1-{[4-(4-sulfamoyl-phenylamino)-pyrimidin-2-ylcarbamoyl]-methyl}-pyridinium; perchlorate | Drug Info |
| EGFR3 --- HER2 | CHEMBL402339 | Drug Info |
| CAII --- CAI | Trans-1(R)S,2S(R)-2-(2,3-dibromo-4,5-dimethoxybenzyl)cyclohexanol | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-5-(5-(pyrrolidin-1-yl)pent-1-ynyl)pyrimidin-4-amine | Drug Info |
| CAII --- CAI | 2-(N-Methyl-guanidino)-N-{4-[3-methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2Z)-ylidenesulfamoyl]-phenyl}-acetamide | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(thiophen-2-yl)thieno[3,2-d]pyrimidin-4-amine | Drug Info |
| CAII --- CAI | 4-methoxybenzoic acid | Drug Info |
| EGFR3 --- HER2 | {4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl}-carbamic acid piperidin-4-ylmethyl ester | Drug Info |
| CAII --- CAI | 3-(4-sulfamoylphenyl)propanoic acid | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid [4-(1-benzyl-1H-indazol-5-ylamino)-3-cyano-7-methoxy-quinolin-6-yl]-amide | Drug Info |
| CAII --- CAI | Trifluoro-methanesulfonic acid 2-sulfamoyl-benzothiazol-6-yl ester | Drug Info |
| EGFR3 --- HER2 | 2-(2-Methyl-5-nitro-1H-imidazol-1-yl)-N-(phenylsulfonyl)acetamide | Drug Info |
| CAII --- CAI | {(2-{Carboxymethyl-[(2-fluoro-4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-ethyl)-[(2-fluoro-4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-acetic acid | Drug Info |
| EGFR3 --- HER2 | But-2-enedioic acid [4-(3-bromo-phenylamino)-pyrido[3,4-d]pyrimidin-6-yl]-amide (3-diethylamino-propyl)-amide | Drug Info |
| CAII --- CAI | sodium iminodisulfate | Drug Info |
| CAII --- CAI | (1R,2R)-4-((8S,9S,12R,14R,17S)-3-(R)-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid 4-sulfamoyl-benzyl ester | Drug Info |
| CAII --- CAI | 4-Methyl-5-(4-pentafluorobenzenesulfonylamino-benzenesulfonylimino)-4,5-dihydro-[1,3,4]thiadiazole-2-sulfonic acid amide | Drug Info |
| CAII --- CAI | [[2-(2-{2-[Carboxymethyl-(2-sulfamoyl-benzothiazol-6-yloxycarbonylmethyl)-amino]-ethoxy}-ethoxy)-ethyl]-(2-sulfamoyl-benzothiazol-6-yloxycarbonylmethyl)-amino]-acetic acid | Drug Info |
| CAII --- CAI | (2-{[(4-Sulfamoyl-benzylcarbamoyl)-methyl]-amino}-ethylamino)-acetic acid | Drug Info |
| CAII --- CAI | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-Heptadecafluoro-nonanoic acid (2,3-dichloro-4,6-disulfamoyl-phenyl)-amide | Drug Info |
| CAII --- CAI | 2-[(1E)-{[2-(4-sulfamoylphenyl)ethyl]imino}methyl]phenyl N-(benzenesulfonyl)carbamate | Drug Info |
| CAII --- CAI | 2-Butyl-hexanoic acid (5-sulfamoyl-indan-2-yl)-amide | Drug Info |
| CAII --- CAIX | 1,4-phenylene disulfamate | Drug Info |
| CAIX --- CAXII | N-[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]sulfamide | Drug Info |
| CALM2 --- Cathepsin B | Benzenesulfonic acid (3S,5R)-1-benzenesulfonyl-5-((S)-1-benzyl-2-oxo-ethylcarbamoyl)-pyrrolidin-3-yl ester | Drug Info |
| CALM2 --- Cathepsin B | (R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-ethanesulfonylamino-propionamide | Drug Info |
| CALM2 --- Cathepsin B | (3-Methyl-1-{1-[3-(3,4,4a,8a-tetrahydro-1H-isoquinolin-2-yl)-propylaminooxalyl]-propylcarbamoyl}-butyl)-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- Cathepsin B | Benzofuran-2-carboxylic acid {3-methyl-1-[2-oxo-3-(pyridine-2-sulfonylamino)-propylcarbamoyl]-butyl}-amide | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-(2,2-dimethyl-propylamino)-pyrimidine-5-carboxylic acid {2-[3-(2-imidazol-1-yl-ethoxy)-phenyl]-ethyl}-amide | Drug Info |
| Cathepsin K --- MEP | SID85147302 | Drug Info |
| Cathepsin K --- MEP | (S)-N-((R)-2-(benzyloxy)-1-cyanoethyl)-4-methyl-2-(2-(4-phenylpiperidin-1-yl)acetamido)pentanamide | Drug Info |
| Cathepsin K --- MEP | (S)-2-((S)-1-(4-benzoylphenyl)-2,2,2-trifluoroethylamino)-N-(cyanomethyl)-4-methylpentanamide | Drug Info |
| Cathepsin K --- MEP | (S)-4,4-dimethyl-2-oxo-tetrahydrofuran-3-yl (S)-1,2-dioxo-1-((R)-1-phenylethylamino)heptan-3-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | (S)-N-(1-(2-(4-chlorophenylamino)ethylamino)-4-methyl-1-oxopentan-2-yl)-3-methylbenzamide | Drug Info |
| Cathepsin K --- MEP | N-[1-(2S-Ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2-(1-methyl-cyclopentyl)-ethyl]-4-methanesulfonylamino-3-methyl-benzamide | Drug Info |
| Cathepsin K --- MEP | N-[1-(2S-Ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-4-(toluene-2-sulfonylamino)-benzamide | Drug Info |
| CCKBR --- CCKAR | 3-(2-{[2-(3-tert-Butoxycarbonylamino-propionylamino)-3-(1H-indol-3-yl)-propionyl]-methyl-amino}-hexanoylamino)-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid | Drug Info |
| CCKBR --- CCKAR | [1-[2-(2,4-Dichloro-phenyl)-ethylcarbamoyl]-2-(1H-indol-3-yl)-1-methyl-ethyl]-carbamic acid adamantan-2-yl ester | Drug Info |
| CCKBR --- CCKAR | 1H-Indole-2-carboxylic acid ((R)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-amide | Drug Info |
| CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(4-chloro-phenyl)-acryloylamino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid; hydrate | Drug Info |
| CCKBR --- CCKAR | Morpholine-4-carboxylic acid (R)-3-(4-benzoyl-piperidin-1-yl)-3-oxo-2-(3-m-tolyl-ureido)-propyl ester | Drug Info |
| CCKBR --- CCKAR | N-(1-Carbamoyl-2-phenyl-ethyl)-3-{2-[3-(1H-indol-3-yl)-2-(2-{2-[3-(4-sulfonyl-oxy-phenyl)-propionylamino]-hexanoylamino}-acetylamino)-propionylamino]-hexanoylamino}-succinamic acid | Drug Info |
| CCKBR --- CCKAR | N-(1-Carbamoyl-2-phenyl-ethyl)-3-{[(5R,8R)-8-(1H-indol-3-ylmethyl)-8-methyl-7,10-dioxo-1,2-dithia-6,9-diaza-cyclotetradecane-5-carbonyl]-amino}-succinamic acid | Drug Info |
| CCKBR --- CCKAR | 4-(4-Benzoyl-piperidin-1-yl)-4-(R)-oxo-3-(3-m-tolyl-ureido)-butyric acid benzyl ester | Drug Info |
| CCKBR --- CCKAR | (S)-3-Bromo-N-[5-(2-fluoro-phenyl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-benzamide | Drug Info |
| CCKBR --- CCKAR | N-{1-[1-[({2-[2-tert-Butoxycarbonylamino-3-(4-sulfooxy-phenyl)-propionylamino]-hexanoylamino}-methyl)-carbamoyl]-2-(1H-indol-3-yl)-ethylcarbamoyl]-pentyl}-3-(2-carbamoyl-3-phenyl-propionylamino)-succinamic acid | Drug Info |
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