Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CCKBR --- CCKAR | 3-tert-Butoxycarbonylamino-N-[1-[1-({[1-{1-[1-(2-carbamoyl-3-phenyl-propionylamino)-2-carboxy-ethylcarbamoyl]-pentylcarbamoyl}-2-(1H-indol-3-yl)-ethylcarbamoyl]-methyl}-carbamoyl)-pentylcarbamoyl]-2-(4-sulfooxy-phenyl)-ethyl]-succinamic acid | Drug Info |
| CCKBR --- CCKAR | N-[5-(2-Fluoro-phenyl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-2-(3-methoxy-phenyl)-acetamide: 0.16CH2Cl2 | Drug Info |
| CCKBR --- CCKAR | [2-(1H-Indol-3-yl)-1-methyl-1-(2-naphthalen-1-yl-ethylcarbamoyl)-ethyl]-carbamic acid adamantan-2-yl ester | Drug Info |
| CCKBR --- CCKAR | N-tert-Butyl-2-{(3R,5S,7R)-3-[3-(4-methoxy-phenyl)-ureido]-2-oxo-7-phenyl-5-o-tolyl-azepan-1-yl}-acetamide | Drug Info |
| CCKBR --- CCKAR | 3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-5-(3-o-tolyl-ureido)-pentanoylamino]-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid | Drug Info |
| CCKBR --- CCKAR | (S)-Quinoline-3-carboxylic acid [1-dipentylcarbamoyl-2-(1H-indol-3-yl)-ethyl]-amide | Drug Info |
| CCKBR --- CCKAR | (Benzyl-{3-(1H-indol-3-yl)-2-[(quinoline-3-carbonyl)-amino]-propionyl}-amino)-acetic acid ethyl ester | Drug Info |
| CCKBR --- CCKAR | (+/-)-2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-4-chloro-N-(2-(3,4-dichlorophenyl)propyl)benzamide | Drug Info |
| CCKBR --- CCKAR | 3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-(3-tert-butyl-ureido)-hexanoylamino]-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid | Drug Info |
| CD135 --- Ckit | N-(3-(5-amino-1-(pyridin-2-yl)-1H-1,2,4-triazol-3-ylamino)phenyl)acetamide | Drug Info |
| CD221 --- JNK1 | 2-(2-(1-(2-(azetidin-1-yl)acetyl)-5-methoxyindolin-6-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-6-fluorobenzamide | Drug Info |
| CDK1 --- CDK2 | (Z)-4-(2-(5-(methylsulfonyl)-2-oxoindolin-3-ylidene)hydrazinyl)benzenesulfonamide | Drug Info |
| CDK1 --- CDK2 | SID103904953 | Drug Info |
| CDK1 --- GSK3 | SID103905441 | Drug Info |
| CDK1 --- GSK3 | 3-(4-Amino-butoxy)-9-bromo-5,12-dihydro-7H-benzo[2,3]azepino[4,5-b]indol-6-one; hydrochloride | Drug Info |
| CDK1 --- GSK3 | SID527397 | Drug Info |
| CDK1 --- VEGFR | 3-{5-[4-(4-Morpholin-4-yl-phenylamino)-[1,3,5]triazin-2-yl]-pyridin-3-ylamino}-propan-1-ol | Drug Info |
| CDK2 --- AKT | (S)-6-(2-(2-amino-3-(4-(trifluoromethyl)phenyl)propylamino)thiazol-5-yl)benzo[d]oxazol-2(3H)-one | Drug Info |
| CDK2 --- AuroraA | N,1,4,4-Tetramethyl-8-({4-[(1-methylpiperidin-4-yl)oxy]phenyl}-amino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | (S)-N-{1-(3-Chlorophenyl)-2-hydroxyethyl}-4-{5-methyl-2-(phenylamino)pyrimidin-4-yl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- CDK1 | GW301784X | Drug Info |
| CDK2 --- CDK1 | 4-[N'-(6-Cyclohexylmethoxy-9H-purin-2-yl)-hydrazino]-benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | CHEMBL462385 | Drug Info |
| CDK2 --- CDK1 | (6-Cyclohexylmethoxy-9H-purin-2-yl)-thiophen-2-ylmethyl-amine | Drug Info |
| CDK2 --- CDK1 | 3-[(2,2-Dioxo-2,3-dihydro-1H-2lambda*6*-benzo[c]thiophen-5-ylamino)-methylene]-5-oxazol-5-yl-1,3-dihydro-indol-2-one | Drug Info |
| CDK2 --- CDK1 | (Z)-4-(2-(5-amino-2-oxoindolin-3-ylidene)hydrazinyl)benzenesulfonamide | Drug Info |
| CDK2 --- CDK4 | 8-Cyclopentyl-5-methyl-7-oxo-2-(4-piperazin-1-yl-phenylamino)-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid methyl ester | Drug Info |
| CDK2 --- CDK4 | (8-Isopropyl-7-methoxy-quinazolin-2-yl)-(4-pyrrolidin-1-yl-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | 1-(5-Cyclopentylaminomethyl-1H-pyrazol-3-yl)-3-(5-oxo-2,3,5,9b-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-urea | Drug Info |
| CDK2 --- CDK4 | [4-(2-Methyl-imidazo[1,2-a]pyridin-3-yl)-pyrimidin-2-yl]-phenyl-amine | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((5-m-tolylthiophen-2-yl)methyl)-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | 2-{(2-Hydroxy-ethyl)-[6-(4-methoxy-benzylamino)-9-(4-nitro-benzyl)-9H-purin-2-yl]-amino}-ethanol | Drug Info |
| CDK2 --- Cyclin E | 5-(2-chlorophenyl)-7-nitro-3-phenethyl-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine | Drug Info |
| CDK2 --- Cyclin E | N-[5-(5-tert-Butyl-oxazol-2-ylmethylsulfanyl)-thiazol-2-yl]-2-phenyl-acetamide | Drug Info |
| CDK2 --- Cyclin E | 4-((R)-Amino-5-hydroxy-3-(S)-4-hydroxy-hex-1-ynyl)-5-fluoro-3-(3-methoxy-1H-pyrrol-2-ylmethylene)-1,3-dihydro-indol-2-one | Drug Info |
| CDK2 --- Cyclin E | 1-[5-(5-tert-Butyl-oxazol-2-ylmethylsulfanyl)-thiazol-2-yl]-3-ethyl-urea | Drug Info |
| CDK2 --- Cyclin E | N-[5-(4,5-Dimethyl-oxazol-2-ylmethylsulfanyl)-thiazol-2-yl]-acetamide | Drug Info |
| CDK2 --- GSK3 | SB-725317 | Drug Info |
| CAII --- CAI | SID49680046 | Drug Info |
| CDK2 --- JNK1 | 4-(5-chloro-4-(1H-indol-1-yl)pyrimidin-2-ylamino)-N-ethylpiperidine-1-carboxamide | Drug Info |
| CAII --- CAI | 4-(3-Pyridin-2-ylmethyl-thioureido)-benzenesulfonamide | Drug Info |
| Chk --- Met | CHEMBL1197528 | Drug Info |
| CAII --- CAI | 2-methyl-N-(4-sulfamoylphenyl)pentanamide | Drug Info |
| Ckit --- BRaf | 2-((2-acetamidopyridin-4-yl)methylamino)-N-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)benzamide | Drug Info |
| CAII --- CAI | 4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-benzoic acid 2-hydroxy-ethyl ester | Drug Info |
| COX2 --- 5LOX | 2,6-Di-tert-butyl-4-((Z)-2-thiophen-2-yl-vinyl)-phenol | Drug Info |
| CAII --- CAI | {{2-[2-(2-{Carboxymethyl-[2-(2-sulfamoyl-benzothiazol-6-yloxy)-ethoxycarbonylmethyl]-amino}-ethoxy)-ethoxy]-ethyl}-[2-(2-sulfamoyl-benzothiazol-6-yloxy)-ethoxycarbonylmethyl]-amino}-acetic acid | Drug Info |
| COX2 --- 5LOX | 2-Chloro-6-methyl-4-(2-thiophen-2-yl-vinyl)-phenol | Drug Info |
| CAII --- CAI | [2-({[2-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-ethylcarbamoyl]-methyl}-amino)-ethylamino]-acetic acid | Drug Info |
| COX2 --- HRH1 | 11-(2-Morpholin-4-yl-ethylsulfanyl)-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid | Drug Info |
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