Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CAII --- CAI | [(2-{[2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-ethyl)-(4-sulfamoyl-benzyloxycarbonylmethyl)-amino]-acetic acid | Drug Info |
| COX2 --- 5LOX | 5-(4-Chloro-phenyl)-3-[3-fluoro-5-(4-methoxy-tetrahydro-pyran-4-yl)-phenoxymethyl]-pyrazole-1-sulfonic acid amide | Drug Info |
| CAII --- CAI | 5-(4-Amino-3-iodo-benzenesulfonylamino)-[1,3,4]thiadiazole-2-sulfonic acid amide | Drug Info |
| COX2 --- 5LOX | 2-Fluoro-6-methoxy-4-(2-thiophen-2-yl-vinyl)-phenol | Drug Info |
| CAII --- CAI | N-(2-Chloro-4-sulfamoyl-phenyl)-2-(N-methyl-guanidino)-acetamide | Drug Info |
| CSrc --- CABL | 6-Methoxy-4-(5-methoxy-2-methyl-phenylamino)-7-(1-methyl-piperidin-4-ylmethoxy)-quinoline-3-carbonitrile | Drug Info |
| CAII --- CAI | 2-(N-Methyl-guanidino)-N-[3-methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-ylidene]-acetamide | Drug Info |
| CSrc --- CABL | 4-(2,4-Dimethyl-phenylamino)-6-methoxy-7-(1-methyl-piperidin-4-ylmethoxy)-quinoline-3-carbonitrile | Drug Info |
| CAII --- CAI | (S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-methoxyphenyl)acrylate | Drug Info |
| CSrc --- CABL | 1-(2-chloro-2-phenylethyl)-N-(3-chlorophenethyl)-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| CAII --- CAI | 2-Propyl-pentanoic acid 2-(2-sulfamoyl-benzothiazol-6-yloxy)-ethyl ester | Drug Info |
| CSrc --- CABL | N-(3-(6-(2,6-dichlorophenyl)-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-ylamino)phenyl)acetamide | Drug Info |
| CAII --- CAI | (S)-2-(4-Chloro-3-sulfamoyl-benzoylamino)-3-hydroxy-propionic acid | Drug Info |
| CSrc --- CABL | N-benzyl-1-(2-chloro-2-phenylethyl)-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| CAII --- CAI | 2,4-dichloro-5-sulfamoylbenzoic acid | Drug Info |
| CSrc --- CDK1 | (S)-6-(5-(2-amino-3-(1H-indol-3-yl)propoxy)pyridin-3-yl)isoquinolin-3-amine | Drug Info |
| CAII --- CAI | 2,4,6-Trimethyl-1-[(5-sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-methyl]-pyridinium; perchlorate | Drug Info |
| DHFR --- TYMS | N-[4-[(2,4-Diamino-5-methyl-furo[2,3-d]pyrimidin-6-yl)-thio]-benzoyl]-L-glutamic acid | Drug Info |
| CAII --- CAI | 1-[(5-Chloro-2,4-disulfamoyl-phenylcarbamoyl)-methyl]-2,6-diethyl-4-phenyl-pyridinium; perchlorate | Drug Info |
| DHFR --- TYMS | N-(4-{[(2-Amino-4-oxo-3,4-dihydro[1]benzothieno[2,3-d]pyrimidin-5-yl)methyl]amino}benzoyl)-L-glutamic acid | Drug Info |
| CAII --- CAI | 2,6-Diethyl-1-{[4-(3-methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-2-ylidenesulfamoyl)-phenylcarbamoyl]-methyl}-4-phenyl-pyridinium; perchlorate | Drug Info |
| EGFR --- HER2 | 2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)acrylamide | Drug Info |
| CAII --- CAI | 2-Amino-N-(2-bromo-4-sulfamoyl-phenyl)-acetamide | Drug Info |
| EGFR --- Src | 2,2'-Dithiobis(1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid phenylamide) | Drug Info |
| CAII --- CAI | 1-[(2,3-Dichloro-4,6-disulfamoyl-phenylcarbamoyl)-methyl]-2,6-diisopropyl-4-phenyl-pyridinium; perchlorate | Drug Info |
| EGFR3 --- CSrc | 6-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile | Drug Info |
| CAII --- CAI | (R)-4-((5S,6R,8S,9S,12S,14R,17S)-7-Hydroxy-3-(R)-hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid (2-bromo-4-sulfamoyl-phenyl)-amide | Drug Info |
| EGFR3 --- HER2 | Pentanedioic acid (2R,5R)-5-(6-amino-purin-9-yl)-3,4-diisopropoxy-tetrahydro-furan-2-ylmethyl ester 4-((E)-2-nitro-vinyl)-phenyl ester | Drug Info |
| CAII --- CAI | 3-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-ylidenesulfamoyl]-benzoic acid 2-methoxy-ethyl ester | Drug Info |
| EGFR3 --- HER2 | Lapatinib tosylate | Drug Info |
| CAII --- CAI | N,N-dialkylthio-carbonylsulfenylamino derivative | Drug Info |
| EGFR3 --- HER2 | N-[4-(3-Chloro-4-fluoro-phenylamino)-7-(4-morpholin-4-yl-but-1-enyl)-pyrido[3,2-d]pyrimidin-6-yl]-acrylamide | Drug Info |
| CAII --- CAI | 6-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-pyridine-2-carboxylic acid | Drug Info |
| EGFR3 --- HER2 | CANERTINIB DIHYDROCHLORIDE | Drug Info |
| CAII --- CAI | N-(5-Mercapto-[1,3,4]thiadiazol-2-yl)-4-sulfamoyl-benzamide | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(naphthalen-1-ylmethoxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide | Drug Info |
| CAII --- CAI | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-Heptadecafluoro-nonanoic acid [4-(4-sulfamoyl-phenylamino)-pyrimidin-2-yl]-amide | Drug Info |
| EGFR3 --- HER2 | 7-(4-(3-chloro-4-fluorophenylamino)-6-methoxyquinazolin-7-yloxy)-N-hydroxyheptanamide | Drug Info |
| CAII --- CAI | 4-Methylsulfanyl-2-[3-(4-sulfamoyl-phenyl)-thioureido]-butyric acid | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid [4-(3-chloro-4-cyclohexylmethoxy-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| CAII --- CAI | {{2-[Carboxymethyl-(2-{carboxymethyl-[(2-chloro-4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-ethyl)-amino]-ethyl}-[(2-chloro-4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-acetic acid | Drug Info |
| CAII --- CAI | N-(3-benzoylphenyl)sulfamide | Drug Info |
| CAII --- CAI | (2-{[(3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-2-ylidenecarbamoyl)-methyl]-amino}-ethylamino)-acetic acid | Drug Info |
| CAII --- CAI | 4-(4-m-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide | Drug Info |
| CAII --- CAI | SID24793716 | Drug Info |
| CAII --- CAI | 3-[2-(2-Amino-acetylamino)-acetylamino]-N-(5-sulfamoyl-[1,3,4]thiadiazol-2-yl)-propionamide | Drug Info |
| CAII --- CAI | 4-(4-(4-methoxy-2-methylphenyl)-1H-1,2,3-triazol-1-yl)benzenesulfonamide | Drug Info |
| CAII --- CAI | 3-Hydroxy-2-[3-(4-sulfamoyl-phenyl)-thioureido]-propionic acid | Drug Info |
| CAII --- CAIX | 2-(N''-Acetyl-hydrazino)-benzenesulfonamide | Drug Info |
| CAIX --- CAXII | SID170466302 | Drug Info |
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