Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CAII --- CAI | 2,3,4,5,6-Pentafluoro-N-(2-iodo-4-sulfamoyl-phenyl)-benzamide | Drug Info |
| CSrc --- CD221 | N-{[4'-({2-[2-(1H-Indol-3-yl)-2-oxoacetyl]hydrazino}carbonyl)[1,1'-biphenyl]-3-yl]methyl}methanesulfonamide | Drug Info |
| CAII --- CAI | (R)-4-((1R,5S,7S,8R,12S,15S)-10,13-Dimethyl-3,7,12-trioxo-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid (2,3-dichloro-4,6-disulfamoyl-phenyl)-amide | Drug Info |
| CSrc --- TEK | 3-{4-[(Furan-2-ylmethyl)-amino]-3-methoxy-phenyl}-1-[4-(4-methyl-piperazin-1-yl)-cyclohexyl]-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine | Drug Info |
| CAII --- CAI | (R)-4-((8S,10S,12S,14R,15R,17S)-3,12-Di(R)-hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid 2-sulfamoyl-benzothiazol-6-yl ester | Drug Info |
| DHFR --- TYMS | 2-Amino-5-[(3-chlorophenyl)sulfanyl]-6-ethylthieno[2,3-d]pyrimidin-4(3H)-one | Drug Info |
| CAII --- CAI | (2-{[(2-Bromo-4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-ethylamino)-acetic acid | Drug Info |
| EGFR --- HER2 | 2-[(E)-2-Cyano-3-(3,4-dihydroxy-phenyl)-acryloylamino]-3-phenyl-propionic acid ethyl ester | Drug Info |
| CAII --- CAI | (Z)-5-(((1R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methylsulfonylimino)-4-methyl-4,5-dihydro-1,3,4-thiadiazole-2-sulfonamide | Drug Info |
| EGFR --- Src | CHEMBL1739089 | Drug Info |
| CAII --- CAI | (R)-4-((8S,10S,12S,14R,15R,17S)-10,13-Dimethyl-3,7,12-trioxo-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid 2-sulfamoyl-benzothiazol-6-yl ester | Drug Info |
| EGFR3 --- CSrc | N-(2-chloro-6-methylphenyl)-2-[(cyclopropylcarbonyl)amino]-1,3-thiazole-5-carboxamide | Drug Info |
| CAII --- CAI | [(2-Hydroxy-phenyl)-(2-{(2-hydroxy-phenyl)-[(2-iodo-4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-ethyl)-amino]-acetic acid | Drug Info |
| EGFR3 --- HER2 | But-2-enedioic acid [4-(3-bromo-phenylamino)-pyrido[3,4-d]pyrimidin-6-yl]-amide (3-imidazol-1-yl-propyl)-amide | Drug Info |
| CAII --- CAI | (S)-3-(4-Hydroxy-phenyl)-2-(4-sulfamoyl-benzoylamino)-propionic acid | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(naphthalen-2-ylmethoxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide | Drug Info |
| CAII --- CAI | (S)-3-(1H-Indol-3-yl)-2-[3-(4-sulfamoyl-phenyl)-thioureido]-propionic acid methylcarbamoylmethyl with resin | Drug Info |
| EGFR3 --- HER2 | 2-(2-(5-Fluoro-2-hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one | Drug Info |
| CAII --- CAI | {2-[(4-Sulfamoyl-benzyloxycarbonylmethyl)-amino]-ethylamino}-acetic acid | Drug Info |
| EGFR3 --- HER2 | 4-Morpholin-4-yl-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| CAII --- CAI | N,N-dialkylthio-carbonylsulfenylamino derivative | Drug Info |
| EGFR3 --- HER2 | 1-(2-(4-(3-fluoro-4-(6-methylpyridin-3-yloxy)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3-yloxy)ethyl)piperidin-4-ol | Drug Info |
| CAII --- CAI | 4-nitrophenylsulfamide | Drug Info |
| EGFR3 --- HER2 | (E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(naphthalen-2-yl)acrylate | Drug Info |
| CAII --- CAI | 6-Amino-2-[3-(4-sulfamoyl-phenyl)-thioureido]-hexanoic acid | Drug Info |
| EGFR3 --- HER2 | But-2-enedioic acid [4-(3-bromo-phenylamino)-pyrido[3,4-d]pyrimidin-6-yl]-amide (3-diethylamino-propyl)-amide | Drug Info |
| CAII --- CAI | sodium iminodisulfate | Drug Info |
| CAII --- CAI | (1R,2R)-4-((8S,9S,12R,14R,17S)-3-(R)-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid 4-sulfamoyl-benzyl ester | Drug Info |
| CAII --- CAI | 4-Methyl-5-(4-pentafluorobenzenesulfonylamino-benzenesulfonylimino)-4,5-dihydro-[1,3,4]thiadiazole-2-sulfonic acid amide | Drug Info |
| CAII --- CAI | [[2-(2-{2-[Carboxymethyl-(2-sulfamoyl-benzothiazol-6-yloxycarbonylmethyl)-amino]-ethoxy}-ethoxy)-ethyl]-(2-sulfamoyl-benzothiazol-6-yloxycarbonylmethyl)-amino]-acetic acid | Drug Info |
| CAII --- CAI | (2-{[(4-Sulfamoyl-benzylcarbamoyl)-methyl]-amino}-ethylamino)-acetic acid | Drug Info |
| CAII --- CAI | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-Heptadecafluoro-nonanoic acid (2,3-dichloro-4,6-disulfamoyl-phenyl)-amide | Drug Info |
| CAII --- CAI | 2-[(1E)-{[2-(4-sulfamoylphenyl)ethyl]imino}methyl]phenyl N-(benzenesulfonyl)carbamate | Drug Info |
| CAII --- CAI | 2-Butyl-hexanoic acid (5-sulfamoyl-indan-2-yl)-amide | Drug Info |
| CAII --- CAIX | 1,4-phenylene disulfamate | Drug Info |
| CAIX --- CAXII | N-[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]sulfamide | Drug Info |
| CALM2 --- Cathepsin B | Benzenesulfonic acid (3S,5R)-1-benzenesulfonyl-5-((S)-1-benzyl-2-oxo-ethylcarbamoyl)-pyrrolidin-3-yl ester | Drug Info |
| CALM2 --- Cathepsin B | (R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-ethanesulfonylamino-propionamide | Drug Info |
| CALM2 --- Cathepsin B | (3-Methyl-1-{1-[3-(3,4,4a,8a-tetrahydro-1H-isoquinolin-2-yl)-propylaminooxalyl]-propylcarbamoyl}-butyl)-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- Cathepsin B | Benzofuran-2-carboxylic acid {3-methyl-1-[2-oxo-3-(pyridine-2-sulfonylamino)-propylcarbamoyl]-butyl}-amide | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-(2,2-dimethyl-propylamino)-pyrimidine-5-carboxylic acid {2-[3-(2-imidazol-1-yl-ethoxy)-phenyl]-ethyl}-amide | Drug Info |
| Cathepsin K --- MEP | SID85147302 | Drug Info |
| Cathepsin K --- MEP | (S)-N-((R)-2-(benzyloxy)-1-cyanoethyl)-4-methyl-2-(2-(4-phenylpiperidin-1-yl)acetamido)pentanamide | Drug Info |
| Cathepsin K --- MEP | (S)-2-((S)-1-(4-benzoylphenyl)-2,2,2-trifluoroethylamino)-N-(cyanomethyl)-4-methylpentanamide | Drug Info |
| Cathepsin K --- MEP | N-((S)-3-cyclohexyl-1-((S)-4-(methylsulfonyl)-1-(4-(trifluoromethoxy)phenylamino)butan-2-ylamino)-1-oxopropan-2-yl)morpholine-4-carboxamide | Drug Info |
| Cathepsin K --- MEP | 4-[2-(1-Methyl-piperidin-4-yl)-ethoxy]-6-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrimidine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | (S)-ethyl 3-(4-cyclohexyl-2-(3-methoxybenzamido)butanamido)-4-(5-fluoroindolin-1-yl)butanoate | Drug Info |
| Cathepsin K --- MEP | {(S)-1-[(S)-1-Benzyl-2-(4-morpholin-4-yl-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | 4-Isopropyl-N-{1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-benzamide | Drug Info |
| CCKBR --- CCKAR | 4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-butyric acid | Drug Info |
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