Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CAII --- CAI | (4-Sulfamoyl-benzoylamino)-acetic acid | Drug Info |
| CAII --- CAI | (S)-2-[3-(4-Sulfamoyl-phenyl)-thioureido]-propionic acid 4-methylcarbamoylmethoxy-benzyl with resin | Drug Info |
| CAII --- CAI | (S)-2-(4-Chloro-3-sulfamoyl-benzoylamino)-3-(4-hydroxy-phenyl)-propionic acid | Drug Info |
| CAII --- CAI | 2-Propyl-pentanoic acid 2-sulfamoyl-benzothiazol-6-yl ester | Drug Info |
| CAII --- CAIX | 4-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl)-1-[alpha-(4-N,N-dimethylaminophenyl)methylene]semicarbazide | Drug Info |
| CAIX --- CAXII | 7-Benzyloxycoumarin | Drug Info |
| CALM2 --- Cathepsin B | (R)-1-(4-bromophenylsulfonyl)-N-((R,S)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide | Drug Info |
| CALM2 --- Cathepsin B | (3-Methyl-1-{1-[2-(1-methyl-1H-pyrrol-2-yl)-ethylaminooxalyl]-propylcarbamoyl}-butyl)-carbamic acid benzyl ester | Drug Info |
| CALM2 --- Cathepsin B | (R)-2-(4-fluorophenylsulfonamido)-3-methyl-N-((R)-4-methyl-1-oxopentan-2-yl)butanamide | Drug Info |
| Cathepsin K --- Cathepsin B | [(S)-2-(3-Fluoro-phenyl)-1-((5S,6R)-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-ethyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | CHEMBL1672434 | Drug Info |
| Cathepsin K --- MEP | N-{(S)-2-Cyclohexyl-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-ethyl}-4-piperazin-1-yl-benzamide | Drug Info |
| Cathepsin K --- MEP | benzyl (S)-1-((S)-1-cyano-2-m-tolylethylamino)-4-methyl-1-oxopentan-2-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | 3-Methoxy-N-{(S)-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-benzamide | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((2S,3S)-2-tert-Butoxy-4-oxo-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | (R,S)-4-methyl-2-[3'-(2-piperazin-1-yl-thiazol-4-yl)-biphenyl-3-yl]-pentanoic acid cyanomethyl-amide | Drug Info |
| Cathepsin K --- MEP | (S)-N-(cyanomethyl)-4-methyl-2-((S)-1,1,1-trifluorohexan-2-ylamino)pentanamide | Drug Info |
| Cathepsin K --- MEP | ((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-cyclohexyl ester | Drug Info |
| CCKBR --- CCKAR | 2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-N-((1S,2R)-1-(3-bromophenyl)-1-hydroxypropan-2-yl)-4-chlorobenzamide | Drug Info |
| CCKBR --- CCKAR | 3-({1-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionyl]-3-propyl-pyrrolidine-2-carbonyl}-amino)-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid | Drug Info |
| CCKBR --- CCKAR | Tyr-D-Nle-Gly-D-Trp-NMeNle-Asp-Phe-NH2 | Drug Info |
| CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[(quinoline-3-carbonyl)-amino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid | Drug Info |
| CCKBR --- CCKAR | N-(1-Methyl-cyclohexyl)-2-[(3R,5S,7R)-2-oxo-7-phenyl-5-o-tolyl-3-(3-m-tolyl-ureido)-azepan-1-yl]-acetamide | Drug Info |
| CCKBR --- CCKAR | H-Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-Nle-D-Trp-2-Adoc | Drug Info |
| CCKBR --- CCKAR | N-[5-(2-Fluoro-phenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-3-phenyl-acrylamide: 0.65H2O | Drug Info |
| CCKBR --- CCKAR | 3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-(3-phenyl-propionylamino)-hexanoylamino]-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid.2AcOH | Drug Info |
| CCKBR --- CCKAR | CCK7 analogue | Drug Info |
| CCKBR --- CCKAR | H-Tyr-D-Ala-Gly-Phe-NH-NH-D-Phe-D-Asp-D-Nle-Trp-H | Drug Info |
| CCKBR --- CCKAR | [(S)-1-((4aR,5R)-2-Benzyl-1,3-dioxo-octahydro-pyrido[1,2-c]pyrimidin-5-ylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-carbamic acid tert-butyl ester | Drug Info |
| CD135 --- Ckit | 1-(4-(3-aminobenzo[d]isoxazol-4-yl)phenyl)urea | Drug Info |
| CD221 --- JNK1 | 2-(2-(4-chloro-5-(3-(dimethylamino)propoxy)-2-methoxyphenylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-6-fluorobenzamide | Drug Info |
| CDK1 --- CDK2 | 4-{N'-[7-oxo-6,7-dihydro-thiazolo[5,4-e]indol-(8Z)-ylidene]-hydrazino}-benzenesulfonamide | Drug Info |
| CDK1 --- CDK2 | 4-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-benzoic acid | Drug Info |
| CDK1 --- CDK4 | (S)-2(1-Hydroxybut-2-ylamino)-6-[(2-pyridyl)methylamino]-9-iso-propylpurine | Drug Info |
| CDK1 --- GSK3 | 8-Isopropyl-9-oxo-8,9-dihydro-thiazolo[5,4-f]quinazoline-2-carboximidic acid benzyl ester | Drug Info |
| CDK1 --- GSK3 | SID526486 | Drug Info |
| CDK1 --- VEGFR | 5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1H-indol-6-yl)pyrimidin-2-amine | Drug Info |
| CDK2 --- AKT | (S)-3-(2-chlorophenyl)-N1-(5-(3-methyl-1H-indazol-5-yl)-1,3,4-thiadiazol-2-yl)propane-1,2-diamine | Drug Info |
| CDK2 --- AuroraA | 1-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylic acid | Drug Info |
| CDK2 --- AuroraA | 8-[(3-Methoxyphenyl)amino]-1-methyl-4,5-dihydro-1H-pyrazolo-[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- CDK1 | 2-oxo-3-[1-(4-sulfamoyl-phenylamino)-meth-(Z)-ylidene]-2,3-dihydro-1H-indole-5-carboxylic acid methyl ester | Drug Info |
| CDK2 --- CDK1 | CHEMBL451462 | Drug Info |
| CDK2 --- CDK1 | 4-[5-(3-Methoxy-phenyl)-2H-pyrazol-3-ylamino]-benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | 4-[6-Amino-5-(2,6-difluoro-benzoyl)-pyridin-2-ylamino]-benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | 2-[4-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-phenyl]-acetamide | Drug Info |
| CDK2 --- CDK1 | 2-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-ethanol | Drug Info |
| CDK2 --- CDK1 | (Z)-4-(2-(4-(4-hydroxyphenethyl)-2-oxoindolin-3-ylidene)hydrazinyl)benzenesulfonamide | Drug Info |
| CDK2 --- CDK4 | GW781673X | Drug Info |
| CDK2 --- CDK4 | (3-Methoxy-5-trifluoromethyl-phenyl)-(4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-yl)-amine | Drug Info |
| CDK2 --- CDK4 | N-(5-(2-(cyclohexyloxy)-5-methylpyrimidin-4-yl)thiazol-2-yl)pyridin-2-amine | Drug Info |
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