Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(4-trifluoromethyl-phenyl)-acryloylamino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid; hydrate | Drug Info |
| CCKBR --- CCKAR | 1-Methyl-1H-indole-2-carboxylic acid [5-(2-fluoro-phenyl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-amide | Drug Info |
| CCKBR --- CCKAR | (S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-[(S)-2-((S)-3-1H-indol-3-yl-2-isobutoxycarbonylamino-propionylamino)-6-(3-o-tolyl-ureido)-hexanoylamino]-N-methyl-succinamic acid | Drug Info |
| CCKBR --- CCKAR | {3-[(1H-Indole-2-carbonyl)-amino]-2-oxo-5-phenyl-2,3-dihydro-benzo[e][1,4]diazepin-1-yl}-acetic acid: 0.3C4H10O. CH2Cl3 | Drug Info |
| CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(4-hydroxy-phenyl)-propionylamino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-N-methyl-succinamic acidAcOH; hydrate | Drug Info |
| CD221 --- JNK1 | 2-(2-(5-(3-(dimethylamino)propyl)-2-methoxy-4-methylphenylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-6-fluorobenzamide | Drug Info |
| CDK1 --- AuroraA | N-(5-(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylamino)pyridin-2-yl)-N-(2-(pyrrolidin-1-yl)ethyl)methanesulfonamide | Drug Info |
| CDK1 --- CDK2 | GW290597X | Drug Info |
| CDK1 --- CDK4 | 2-(2,4-Dichloro-phenyl)-5,7-dihydroxy-8-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-chromen-4-one | Drug Info |
| CDK1 --- GSK3 | 9-Trifluoromethyl-5,12-dihydro-7H-4,5,12-triaza-dibenzo[a,e]azulen-6-one | Drug Info |
| CDK1 --- GSK3 | 3-(3-hydroxy-4-methoxyphenyl)-8H-thieno[2,3-b]pyrrolizin-8-one | Drug Info |
| CDK1 --- VEGFR | 5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1H-indol-3-yl)pyrimidin-2-amine | Drug Info |
| CDK2 --- AKT | (R)-4-(3-(isoquinolin-6-yl)-1,2,4-oxadiazol-5-yl)-1-(4-(trifluoromethyl)phenyl)butan-2-amine | Drug Info |
| CDK2 --- AuroraA | (S)-4-{2-(4-Chloro-2-methylphenylamino)-5-methylpyrimidin-4-yl}-N-{1-(3-chlorophenyl)-2-hydroxyethyl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- AuroraA | (S)-4-{2-(2,3-Dimethylphenylamino)-5-methylpyrimidin-4-yl}-N-{1-(3-chlorophenyl)-2-hydroxyethyl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- CDK1 | 1-[4-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-phenyl]-ethanone | Drug Info |
| CDK2 --- CDK1 | (3S,4S)-1-(3-(2-amino-6-(piperidin-3-yl)pyrimidin-4-yl)-4-hydroxyphenyl)pyrrolidine-3,4-diol | Drug Info |
| CDK2 --- CDK1 | CHEMBL455468 | Drug Info |
| CDK2 --- CDK1 | (Z)-4-(2-(5-iodo-2-oxoindolin-3-ylidene)hydrazinyl)benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | 2-oxo-3-[1-(4-sulfamoyl-phenylamino)-meth-(Z)-ylidene]-2,3-dihydro-1H-indole-4-carboxylic acid ethyl ester | Drug Info |
| CDK2 --- CDK1 | [4-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-phenyl]-acetonitrile | Drug Info |
| CDK2 --- CDK1 | (Z)-4-((5-(3-methylbutanoyl)-2-oxoindolin-3-ylidene)methylamino)benzenesulfonamide | Drug Info |
| CDK2 --- CDK4 | 4-(4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-ylamino)benzonitrile | Drug Info |
| CDK2 --- CDK4 | 8-Cyclopentyl-5-methyl-7-oxo-2-(4-piperazin-1-yl-phenylamino)-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester | Drug Info |
| CDK2 --- CDK4 | (2,3-Dihydro-benzo[1,4]dioxin-6-yl)-[4-(6-methyl-pyrazolo[1,5-b]pyridazin-3-yl)-pyrimidin-2-yl]-amine | Drug Info |
| CDK2 --- CDK4 | 1-{4-[4-(2-Bromo-phenylamino)-pyrimidin-2-ylamino]-phenoxy}-3-dimethylamino-propan-2-ol | Drug Info |
| CDK2 --- Cyclin E | tert-Butyl-(6-furan-2-yl-2-trifluoromethyl-quinazolin-4-yl)-amine | Drug Info |
| CDK2 --- Cyclin E | 2-(5-((2-benzamidothiazol-4-yl)methyl)-4-(4-chlorobenzamido)-4H-1,2,4-triazol-3-ylthio)acetohydrazide | Drug Info |
| CDK2 --- Cyclin E | 4-tert-Butylamino-2-trifluoromethyl-quinazolin-6-ol | Drug Info |
| CDK2 --- Cyclin E | N-[3-(4-Methoxy-phenyl)-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl]-2-thiomorpholin-4-yl-acetamide | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-(4-(4-methylthiophen-2-yl)benzyl)-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | 4-(1-Hydroxy-2-{[9-isopropyl-6-(4-methoxy-benzylamino)-9H-purin-2-yl]-methyl-amino}-ethyl)-benzene-1,2-diol | Drug Info |
| CDK2 --- Cyclin E | N-(3-((2-acetamidothiazol-4-yl)methyl)-5-(cyanomethylthio)-4H-1,2,4-triazol-4-yl)-4-chlorobenzamide | Drug Info |
| CDK2 --- GSK3 | N-(6-(3-hydroxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)cyclopropanecarboxamide | Drug Info |
| CAII --- CAI | 1-[(2-Iodo-4-sulfamoyl-phenylcarbamoyl)-methyl]-2,6-diisopropyl-4-phenyl-pyridinium; perchlorate | Drug Info |
| CDK4 --- Cyclin E | N-[3-(5-chlorothien-3-yl)-4-oxo-2,4-dihydroindeno[1,2-c]pyrazol-5-yl]-2,2-dimethylhydrazinecarboxamide | Drug Info |
| CAII --- CAI | [Carboxymethyl-(2-sulfamoyl-benzothiazol-6-yloxycarbonylmethyl)-amino]-acetic acid | Drug Info |
| Ckit --- BRaf | 5-(pyridin-4-ylmethylamino)-N-(2,2,3,3-tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)thiazole-4-carboxamide | Drug Info |
| CAII --- CAI | 2,6-Diisopropyl-1-{[4-(3-methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-2-ylidenesulfamoyl)-phenylcarbamoyl]-methyl}-4-phenyl-pyridinium; perchlorate | Drug Info |
| Cmet --- CD135 | 2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)nicotinamide | Drug Info |
| CAII --- CAI | 3-Hydroxy-2-(4-sulfamoyl-benzoylamino)-propionic acid | Drug Info |
| COX2 --- 5LOX | Tebufelone | Drug Info |
| CAII --- CAI | N-(2-Fluoro-4-sulfamoyl-phenyl)-2-(N-methyl-guanidino)-acetamide | Drug Info |
| COX2 --- 5LOX | 5-((Z)-3,5-di-tert-butyl-4-hydroxybenzylidene)-2-amino-4-thiazolidinone | Drug Info |
| CAII --- CAI | 2-Propyl-pentanoic acid (2-bromo-4-sulfamoyl-phenyl)-amide | Drug Info |
| CSrc --- AuroraA | K00244 | Drug Info |
| CAII --- CAI | 6,6,7,7,7-Pentafluoro-heptanoic acid [3-methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-ylidene]-amide | Drug Info |
| CSrc --- CABL | (E)-N-(4-Methyl-3-(2-(6-(pyridine-2-yl-amino)-9H-purin-9-yl)vinyl)phenyl)-3-(trifluoromethyl)-benzamide | Drug Info |
| CAII --- CAI | 6-[2-(2-Sulfamoyl-benzothiazol-6-yloxy)-ethoxycarbamoyl]-pyridine-2-carboxylic acid | Drug Info |
| CSrc --- CABL | N-(5-(benzylthio)-1,3,4-thiadiazol-2-yl)-2-chlorobenzamide | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.