Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CCKBR --- CCKAR | N-tert-Butyl-2-[(3R,5S,7R)-5-(2-methoxy-phenyl)-2-oxo-7-phenyl-3-(3-m-tolyl-ureido)-azepan-1-yl]-acetamide | Drug Info |
| CCKBR --- CCKAR | 2-{(3R,5R)-3-[3-(3-Benzenesulfonylaminocarbonyl-phenyl)-ureido]-8-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-N-tert-butyl-acetamide | Drug Info |
| CCKBR --- CCKAR | (S)-N-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-phenyl-acrylamide: 0.25H2O | Drug Info |
| CCKBR --- CCKAR | CHEMBL1172246 | Drug Info |
| CCKBR --- CCKAR | 3-{1-[1-aminobutyl oxycarbonylamino-2-(1H-3-indolyl)ethylcarboxamido]-5-formamido-ortho-methoxy phenylaminopentylcarboxamido}-3-(1-carbamoyl-2-phenylethylcarbamoyl)propanoic acid | Drug Info |
| CCKBR --- CCKAR | N-tert-Butyl-2-[(3R,5S,7R)-2-oxo-7-phenyl-5-p-tolyl-3-(3-m-tolyl-ureido)-azepan-1-yl]-acetamide | Drug Info |
| CD221 --- JNK1 | 2-(2-(1-acetyl-5-methoxyindolin-6-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-6-fluorobenzamide | Drug Info |
| CDK1 --- AuroraA | N-(4-(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylamino)phenyl)-N-isopropylmethanesulfonamide | Drug Info |
| CDK1 --- CDK2 | 4-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-2-methoxy-benzenesulfonamide | Drug Info |
| CDK1 --- CDK4 | 4-[2-(2-Chloro-phenyl)-5,7-dihydroxy-4-oxo-4H-chromen-8-yl]-1-methyl-piperidin-3-one | Drug Info |
| CDK1 --- GSK3 | 9-Bromo-5,12-dihydro-7H-4,5,12-triaza-dibenzo[a,e]azulen-6-one | Drug Info |
| CDK1 --- GSK3 | 3-[({5-[1-(4-Methoxyphenyl)-1H-benzimidazol-6-yl]-1,3,4-oxadiazol-2-yl}sulfanyl)methyl]benzonitrile | Drug Info |
| CDK1 --- HER2 | 1-(5-(3-(5-methoxy-1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl)pyridin-3-yl)-N-methylmethanamine | Drug Info |
| CDK2 --- AKT | (S)-6-(2-(2-amino-3-(4-(trifluoromethyl)phenyl)propylamino)thiazol-5-yl)benzo[d]thiazol-2(3H)-one | Drug Info |
| CDK2 --- AuroraA | 8-(Phenylamino)-1-(propan-2-yl)-4,5-dihydro-1H-pyrazolo[4,3-h]-quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | (S)-N-{1-(3-Methylphenyl)-2-hydroxyethyl}-4-{5-methyl-2-(phenylamino)pyrimidin-4-yl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- CD221 | CHEMBL73303 | Drug Info |
| CDK2 --- CDK1 | N-Methyl-C-{4-[N'-(7-oxo-6,7-dihydro-thiazolo[5,4-e]indol-8-ylidene)-hydrazino]-phenyl}-methanesulfonamide | Drug Info |
| CDK2 --- CDK1 | (3S,4S)-1-(3-(2-amino-6-(cyclohexylamino)pyrimidin-4-yl)-4-hydroxyphenyl)pyrrolidine-3,4-diol | Drug Info |
| CDK2 --- CDK1 | 3-{[2-(1-Hydroxymethyl-2-methyl-propylamino)-9-isopropyl-9H-purin-6-ylamino]-methyl}-phenol | Drug Info |
| CDK2 --- CDK1 | ethyl 4-(4-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-ylamino)phenylsulfonamido)-4-oxobutanoate | Drug Info |
| CDK2 --- CDK1 | 2-oxo-3-[(4-sulfamoyl-phenyl)-hydrazono]-2,3-dihydro-1H-indole-5-sulfonic acid amide | Drug Info |
| CDK2 --- CDK1 | (Z)-4-(2-(5-amino-2-oxoindolin-3-ylidene)hydrazinyl)benzenesulfonamide | Drug Info |
| CDK2 --- CDK4 | 8-Cyclopentyl-5-methyl-7-oxo-2-(4-piperazin-1-yl-phenylamino)-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid methyl ester | Drug Info |
| CDK2 --- CDK4 | (8-Isopropyl-7-methoxy-quinazolin-2-yl)-(4-pyrrolidin-1-yl-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | 1-(5-Cyclopentylaminomethyl-1H-pyrazol-3-yl)-3-(5-oxo-2,3,5,9b-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-urea | Drug Info |
| CDK2 --- CDK4 | [4-(2-Methyl-imidazo[1,2-a]pyridin-3-yl)-pyrimidin-2-yl]-phenyl-amine | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((5-m-tolylthiophen-2-yl)methyl)-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | 2-{(2-Hydroxy-ethyl)-[6-(4-methoxy-benzylamino)-9-(4-nitro-benzyl)-9H-purin-2-yl]-amino}-ethanol | Drug Info |
| CDK2 --- Cyclin E | N2-(trans-4-aminocyclohexyl)-N6-((4'-chlorobiphenyl-4-yl)methyl)-9-isopropyl-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | tert-Butyl-[6-(4-methoxy-phenyl)-2-trifluoromethyl-quinazolin-4-yl]-amine | Drug Info |
| CDK2 --- Cyclin E | (R)-2-(6-(Biphenyl-4-ylmethylamino)-9-propyl-9H-purin-2-ylamino)butan-1-ol | Drug Info |
| CDK2 --- Cyclin E | N6-((6-(1H-pyrazol-1-yl)pyridin-3-yl)methyl)-N2-(4-aminocyclohexyl)-9-isopropyl-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | N2-(4-Aminocyclohexyl)-9-cyclopentyl-N6-(biphenyl-4-ylmethyl)-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | 5-Hydroxy-3-(4-methoxy-phenyl)-2H-indeno[1,2-c]pyrazol-4-one | Drug Info |
| CDK2 --- GSK3 | N-(6-(4-hydroxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)cyclopropanecarboxamide | Drug Info |
| CAII --- CAI | 5-chloro-2-hydroxybenzoic acid | Drug Info |
| CDK4 --- Cyclin E | 1-[3-(2,5-Dimethyl-thiophen-3-yl)-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl]-3-(4-methyl-piperazin-1-yl)-urea | Drug Info |
| CAII --- CAI | sodium 4-(dimethylamino)benzoate | Drug Info |
| Ckit --- BRaf | 1-(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carbamoyl)phenylamino)methyl)pyridin-2-yl)-3-benzylurea | Drug Info |
| CAII --- CAI | 4-(2-(pyridin-4-ylmethyleneamino)ethyl)benzenesulfonamide | Drug Info |
| COX --- PDE | kuraridin | Drug Info |
| CAII --- CAI | 4-(2-{[({[(3,4-dichlorophenyl)amino]carbonyl}amino)carbonothioyl]amino}ethyl)benzenesulfonamide | Drug Info |
| COX2 --- 5LOX | 1-(3,4-dichlorophenyl)-3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)phenoxymethyl]-5-phenyl-1H-pyrazole | Drug Info |
| CAII --- CAI | 3-(Nonafluorobutane-1-sulfonylamino)-N-(5-sulfamoyl-[1,3,4]thiadiazol-2-yl)-propionamide | Drug Info |
| COX2 --- 5LOX | 3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)phenoxymethyl]-1-(4-fluorophenyl)-5-phenyl-1H-pyrazole | Drug Info |
| CAII --- CAI | 2-Methylamino-N-[3-methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2Z)-ylidene]-acetamide | Drug Info |
| CSrc --- CABL | N-(3-fluorobenzyl)-1-(2-phenylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| CAII --- CAI | 2-Amino-N-{2-[4-(2-hydroxy-ethyl)-benzenesulfonylamino]-2-oxo-ethyl}-acetamide | Drug Info |
| CSrc --- CABL | (S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)-propionylamino]-4-carboxy-butyrylamino}-4-carboxy-butyrylamino)-3-methyl-pentanoylamino]-pentanedioic acid | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.