Multi-target agents
Target Pair | Drug Name | |
---|---|---|
CCKBR --- CCKAR | 3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-(3-naphthalen-2-yl-ureido)-hexanoylamino]-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid | Drug Info |
CCKBR --- CCKAR | N-Isopropyl-2-[(3R,5S,7R)-2-oxo-7-phenyl-5-o-tolyl-3-(3-m-tolyl-ureido)-azepan-1-yl]-acetamide | Drug Info |
CCKBR --- CCKAR | (S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-[(S)-2-((S)-3-1H-indol-3-yl-2-phenylacetylamino-propionylamino)-6-(3-o-tolyl-ureido)-hexanoylamino]-N-methyl-succinamic acid | Drug Info |
CCKBR --- CCKAR | (S)-3-[(S)-2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-((E)-3-pyridin-3-yl-acryloylamino)-hexanoylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-N-methyl-succinamic acid | Drug Info |
CCKBR --- CCKAR | CHEMBL2372623 | Drug Info |
CCKBR --- CCKAR | (R)-4-Dipentylcarbamoyl-4-[3-(3-methoxy-phenyl)-ureido]-butyric acid | Drug Info |
CCKBR --- CCKAR | (S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-[(S)-2-[(S)-2-(2,2-dimethyl-propionylamino)-3-1H-indol-3-yl-propionylamino]-6-(3-o-tolyl-ureido)-hexanoylamino]-N-methyl-succinamic acid | Drug Info |
CCKBR --- CCKAR | N-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-4-trifluoromethyl-benzamide | Drug Info |
CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(4-hydroxy-phenyl)-acryloylamino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid | Drug Info |
CD135 --- Ckit | N3-(2-methoxy-5-morpholinophenyl)-1-(pyridin-2-yl)-1H-1,2,4-triazole-3,5-diamine | Drug Info |
CD221 --- JNK1 | 2-(2-(1-(3-(dimethylamino)propanoyl)-5-methoxyindolin-6-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-6-fluorobenzamide | Drug Info |
CDK1 --- AuroraA | N-(5-(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylamino)pyridin-2-yl)-N-(2-(dimethylamino)ethyl)methanesulfonamide | Drug Info |
CDK1 --- CDK2 | 4-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-benzamide | Drug Info |
CDK1 --- CDK4 | 8-Cyclopentyl-5-methyl-2-(4-morpholin-4-yl-phenylamino)-8H-pyrido[2,3-d]pyrimidin-7-one | Drug Info |
CDK1 --- GSK3 | 7-Cyclohexylmethyl-6-(4-methoxy-phenyl)-5H-pyrrolo[2,3-b]pyrazine | Drug Info |
CDK1 --- GSK3 | 6-(4-Methoxy-phenyl)-7-propyl-5H-pyrrolo[2,3-b]pyrazine | Drug Info |
CDK1 --- HER2 | (2-(5-(isoquinolin-4-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-1H-benzo[d]imidazol-4-yl)methanol | Drug Info |
CDK2 --- AKT | (S)-N1-(5-(1H-indazol-5-yl)-1,3,4-thiadiazol-2-yl)-3-(4-(trifluoromethyl)phenyl)propane-1,2-diamine | Drug Info |
CDK2 --- AuroraA | 8-[(4-Carbamoyl-2-methoxyphenyl)amino]-N-(2,6-diethylphenyl)-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
CDK2 --- AuroraA | N-(5-acetyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-4-methoxybenzamide | Drug Info |
CDK2 --- CD221 | CHEMBL1809195 | Drug Info |
CDK2 --- CDK1 | 3-(2-(4-(N-(2-(2-hydroxyethoxy)ethyl)sulfamoyl)phenyl)hydrazono)-2-oxoindoline-5-carboxamide | Drug Info |
CDK2 --- CDK1 | 4-(4-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-ylamino)phenylsulfonamido)-4-oxobutanoic acid | Drug Info |
CDK2 --- CDK1 | 3-(pyridin-4-yl)-2,4-dihydroindeno[1,2-c]pyrazole | Drug Info |
CDK2 --- CDK1 | 4-(5-(4-aminocyclohexylamino)-[1,2,4]triazolo[1,5-a]pyrimidin-7-ylamino)-N,N-dimethylbenzenesulfonamide | Drug Info |
CDK2 --- CDK1 | 8-[1-(2,2-dioxo-2,3-dihydro-1H-2lambda*6*-benzo[c]thiophen-5-ylamino)-meth-(Z)-ylidene]-6,8-dihydro-thiazolo[5,4-e]indol-7-one | Drug Info |
CDK2 --- CDK1 | N-Methyl-4-[(7-oxo-6,7-dihydro-thiazolo[5,4-e]indol-8-ylidenemethyl)-amino]-benzenesulfonamide | Drug Info |
CDK2 --- CDK4 | CHEMBL453655 | Drug Info |
CDK2 --- CDK4 | 4-[(4-Furan-2-yl-3-hydroxy-benzylamino)-methylene]-6-iodo-4Hisoquinoline-1,3-dione | Drug Info |
CDK2 --- CDK4 | CHEMBL100391 | Drug Info |
CDK2 --- CDK4 | 1-(5-Oxo-2,3,5,9b-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-3-(5-pyrrolidin-1-ylmethyl-1H-pyrazol-3-yl)-urea | Drug Info |
CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((6-phenylpyridin-3-yl)methyl)-9H-purine-2,6-diamine | Drug Info |
CDK2 --- Cyclin E | N6-(biphenyl-4-ylmethyl)-N2-(trans-4-(cyclopropylmethylamino)cyclohexyl)-9-isopropyl-9H-purine-2,6-diamine hydrochloride | Drug Info |
CDK2 --- Cyclin E | 5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine-7-carboxamide | Drug Info |
CDK2 --- Cyclin E | N*2*,N*6*-Bis-(4-bromo-phenyl)-9-isopropyl-9H-purine-2,6-diamine | Drug Info |
CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((6-(thiophen-3-yl)pyridin-3-yl)methyl)-9H-purine-2,6-diamine | Drug Info |
CDK2 --- Cyclin E | 6-Fluoromethyl-3-methylsulfanyl-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
CDK2 --- Cyclin E | 1-[(3-Isopropyl-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-ylcarbamoyl)-methyl]-piperidine-4-carboxylic acid amide | Drug Info |
CDK2 --- GSK3 | N-(6-(thiophen-2-yl)-1H-indazol-3-yl)cyclopropanecarboxamide | Drug Info |
CAII --- CAI | 3-Chloro-4-(5,7-dioxo-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-benzenesulfonamide | Drug Info |
CDK4 --- Cyclin E | 2,2-dimethyl-N-(4-oxo-3-thien-2-yl-2,4-dihydroindeno[1,2-c]pyrazol-5-yl)hydrazinecarboxamide | Drug Info |
CAII --- CAI | 4-fluoro-N-(4-sulfamoylphenyl)benzenesulfonamide | Drug Info |
Chk --- Met | CHEMBL1197326 | Drug Info |
CAII --- CAI | (Carboxymethyl-{2-[carboxymethyl-(2-sulfamoyl-benzothiazol-6-yloxycarbonylmethyl)-amino]-ethyl}-amino)-acetic acid | Drug Info |
Ckit --- BRaf | 4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carbamoyl)phenylamino)methyl)picolinamide | Drug Info |
CAII --- CAI | 2-{3-Carboxy-2-[3-(4-sulfamoyl-phenyl)-thioureido]-propionylamino}-succinic acid | Drug Info |
COX2 --- 5LOX | 2,6-Diisopropyl-4-[2-(4-methoxy-phenyl)-vinyl]-phenol | Drug Info |
CAII --- CAI | {(2-{Carboxymethyl-[(2,3-dichloro-4,6-disulfamoyl-phenylcarbamoyl)-methyl]-amino}-ethyl)-[(2,3-dichloro-4,6-disulfamoyl-phenylcarbamoyl)-methyl]-amino}-acetic acid | Drug Info |
COX2 --- 5LOX | 2-Ethyl-6-methoxy-4-(2-thiophen-2-yl-vinyl)-phenol | Drug Info |
CAII --- CAI | N-(2-adamantyl)sulfamide | Drug Info |
Pagination
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