Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CSrc --- Ckit | 3-(2-aminoquinazolin-6-yl)-1-(4-methoxyphenyl)-4-methylpyridin-2(1H)-one | Drug Info |
| CAII --- CAI | 4-{1-[4-(aminosulfonyl)phenyl]-1H-1,2,3-triazol-4-yl}benzenesulfonamide | Drug Info |
| DHFR --- TYMS | CHEMBL3303081 | Drug Info |
| CAII --- CAI | (1R,2R)-4-((8S,9S,12R,14R,17S)-3-(R)-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid (2-sulfamoyl-benzothiazol-6-yl)-amide | Drug Info |
| DHFR --- TYMS | N-{4-[(2-amino-6-methyl-4-oxo-3,4-dihydro-5 H-pyrrolo[3,2-d]pyrimidin-5-yl)methyl]benzoyl}-l-glutamic acid | Drug Info |
| CAII --- CAI | 1-[(2-Chloro-4-sulfamoyl-phenylcarbamoyl)-methyl]-2,6-dimethyl-4-phenyl-pyridinium; perchlorate | Drug Info |
| EGFR --- HER2 | GW284372X | Drug Info |
| CAII --- CAI | 4-amino-5,6-dichlorobenzene-1,3-disulfonamide | Drug Info |
| EGFR3 --- CDK1 | SID11110934 | Drug Info |
| CAII --- CAI | {(2-{Carboxymethyl-[(2-chloro-4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-ethyl)-[(2-chloro-4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-acetic acid | Drug Info |
| EGFR3 --- HER2 | N-[4-(3-Bromo-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide | Drug Info |
| CAII --- CAI | {Carboxymethyl-[(5-sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-methyl]-amino}-acetic acid | Drug Info |
| EGFR3 --- HER2 | 4-(3-chloro-4-fluorobenzylamino)-6-aminopyrimidine-5-carbaldehyde O-methyl oxime | Drug Info |
| CAII --- CAI | N-(2-Bromo-4-sulfamoyl-phenyl)-2,3,4,5,6-pentafluoro-benzenesulfonamide | Drug Info |
| EGFR3 --- HER2 | (S)-N-(3-ethynylphenyl)-5-((morpholin-2-ylmethoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine | Drug Info |
| CAII --- CAI | (R)-4-((8S,10S,12S,14R,15R,17S)-3,12-Di(R)-hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid [2-(4-sulfamoyl-phenyl)-ethyl]-amide | Drug Info |
| EGFR3 --- HER2 | (E)-ethyl 4-(3-(6-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)pyrimidin-4-yloxy)phenylamino)-4-oxobut-2-enoate | Drug Info |
| CAII --- CAI | SID47201870 | Drug Info |
| EGFR3 --- HER2 | N-{4-(3-Chloro-4-fluoro-phenylamino)-7-[3-(4-methyl-piperazin-1-yl)-propoxy]-pyrido[3,2-d]pyrimidin-6-yl}-acrylamide | Drug Info |
| CAII --- CAI | N-[5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl]sulfamide | Drug Info |
| EGFR3 --- HER2 | N-(4-Bromophenylsulfonyl)-2-(4-fluorophenyl)acetamide | Drug Info |
| CAII --- CAI | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-Heptadecafluoro-nonanoic acid (5-chloro-2,4-disulfamoyl-phenyl)-amide | Drug Info |
| EGFR3 --- HER2 | 1-(3,5-Dichloro-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea | Drug Info |
| CAII --- CAI | 4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-benzoic acid 2-methoxy-ethyl ester | Drug Info |
| EGFR3 --- HER2 | N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((2-methoxyethoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine | Drug Info |
| CAII --- CAI | 3-methyl-N-(4-sulfamoylphenyl)pentanamide | Drug Info |
| CAII --- CAI | Ethyl1-(3-(2-(1-ethoxy-1,3-dioxobutan-2-ylidene)hydrazinyl)phenyl)-5-phenyl-3-(5-sulfamoyl-1,3,4-thiadiazol-2-ylcarbamoyl)-1H-pyrazole-4-carboxylate | Drug Info |
| CAII --- CAI | (2-{[(2,3-Dichloro-4,6-disulfamoyl-phenylcarbamoyl)-methyl]-amino}-ethylamino)-acetic acid | Drug Info |
| CAII --- CAI | 4-Benzoyl-1-(3-hydroxyphenyl)-5-phenyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-1H-pyrazole-3-carboxamide | Drug Info |
| CAII --- CAI | 4-[4-(4-Fluoro-phenyl)-[1,2,3]triazol-1-yl]-benzenesulfonamide | Drug Info |
| CAII --- CAI | 3-(Heptadecafluorooctane-1-sulfonylamino)-N-(5-sulfamoyl-[1,3,4]thiadiazol-2-yl)-propionamide | Drug Info |
| CAII --- CAI | 4-(4-o-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide | Drug Info |
| CAII --- CAI | 2-ethyl-N-(4-sulfamoylphenyl)pentanamide | Drug Info |
| CAII --- CAIX | 4-{4-[2-(4-methylhexahydro-1-pyrazinyl)ethylamino(thioxo)methylamino]phenylsulfonamido}-1-benzenesulfonamide | Drug Info |
| CAIX --- CAXII | 1-(3',5'-dimethylphenyl)-3-(4-methyl-2-oxo-2H-chromen-7-yl)urea | Drug Info |
| CALM2 --- Cathepsin B | (R)-3-Benzyloxy-N-[(S)-1-(4-benzyloxy-benzyl)-2-oxo-ethyl]-2-methanesulfonylamino-propionamide | Drug Info |
| CALM2 --- Cathepsin B | (4S)-N-(1-oxo-3-phenylpropan-2-yl)-3-tosylthiazolidine-4-carboxamide | Drug Info |
| CALM2 --- Cathepsin B | [(1S,2S)-1-((S)-1-Benzyl-2-oxo-2-phenethylcarbamoyl-ethylcarbamoyl)-2-isopropyl-cyclopropyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- Cathepsin B | (R)-1-(5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl)-3,3-dimethylbutan-2-yl(S)-1,2-dioxo-1-((R)-1-phenylethylamino)heptan-3-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | 3-Chloro-N-[1-(2S-ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-4-methanesulfonylamino-benzamide | Drug Info |
| Cathepsin K --- MEP | 5-(3-(4,5-dichloro-1H-imidazol-1-yl)prop-1-ynyl)-4-(neopentylamino)pyrimidine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | (S)-2-(7-chlorobenzo[d]oxazol-2-ylamino)-3-cyclohexyl-N-((S)-1-(4-methoxyphenylamino)propan-2-yl)propanamide | Drug Info |
| Cathepsin K --- MEP | N-((S)-3-(4,4-dimethylcyclohexyl)-1-((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)-1-oxopropan-2-yl)furan-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | N-{(S)-2-(2-Chloro-phenyl)-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-ethyl}-3-methyl-benzamide | Drug Info |
| Cathepsin K --- MEP | benzyl (2S,3S)-1-(cyanomethylamino)-3-methyl-1-oxopentan-2-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-(2,2-dimethyl-propylamino)-pyrimidine-5-carboxylic acid {2-[4-(1-methyl-piperidin-4-yloxy)-phenyl]-ethyl}-amide | Drug Info |
| Cathepsin K --- MEP | N-((S)-1-((S)-1-(4-methoxyphenylamino)propan-2-ylamino)-4-methyl-1-oxopentan-2-yl)-3-methylbenzamide | Drug Info |
| CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(3-hydroxy-phenyl)-propionylamino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid; hydarte | Drug Info |
| CCKBR --- CCKAR | (S)-2-(4-bromo-2-(quinoxaline-5-sulfonamido)benzamido)-3-(3-bromo-4-fluorophenyl)propanoic acid | Drug Info |
| CCKBR --- CCKAR | 2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-4-bromo-N-phenethylbenzamide | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.