Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| 5HT1a --- SERT | 6-((1-(2-(6-fluoro-2-methylquinolin-5-yloxy)ethyl)piperidin-4-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one | Drug Info |
| 5HT1a --- SERT | 6-((1-(2-(7-chloro-2-methylquinolin-5-yloxy)ethyl)piperidin-4-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one | Drug Info |
| 5HT1a --- SERT | 6-{2-[2-Hydroxy-3-(1H-indol-4-yloxy)-propylamino]-propoxy}-4H-benzo[1,4]oxazin-3-one | Drug Info |
| 5HT1b --- SERT | (+/-)-(2-(1-(3,4-dichlorophenyl)ethyl)phenyl)-N,N-dimethylmethanamine | Drug Info |
| 5LOX --- HRH1 | 1-{4-[4-(4-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}butoxy)phenyl]but-3-yn-1-yl}-1-hydroxyurea | Drug Info |
| ADRA1A --- HRH1 | 2-{[(2R)-1-methyl-2-pyrrolidinyl]methyl}-4-(2-phenylethyl)-1(2H)-phthalazinone | Drug Info |
| ADRA1A --- HRH1 | SID170465966 | Drug Info |
| ADRA1A --- HRH1 | (R)-4-(3,4-Difluoro-phenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-cyano-4-(2-cyano-phenyl)-piperidin-1-yl]-propyl}-amide | Drug Info |
| CABL --- Ckit | PD-0166326 | Drug Info |
| CABL --- PI3K gamma | PP121 | Drug Info |
| Aurora --- Chk | 2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydro-5Hdibenzo[b,e][1,4]diazepin-8-yl]-N-[4-(4-morpholinyl)phenyl]acetamide | Drug Info |
| Aurora --- VEGFR | 5-(2-(3-(6-methoxy-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)vinyl)nicotinonitrile | Drug Info |
| AuroraA --- STK1 | (R)-tert-butyl 1-(2-amino-6-(3-amino-1H-indazol-6-yl)pyrimidin-4-yl)piperidin-3-ylcarbamate | Drug Info |
| AuroraA --- STK1 | 4-[3-(4-N-Phenylcarbamylaminophenyl)-1-ethyl-1H-pyrazol-4-yl]-2-[3-(N-pyrrolidinylmethyl)phenyl]-1H-pyrrolo[2,3-b]pyridine | Drug Info |
| AuroraA --- STK1 | ALISERTIB | Drug Info |
| AuroraA --- STK1 | 4-[3-(4-N,N-Dimethylcarbamylaminophenyl)-1-ethyl-1H-pyrazol-4-yl]-2-[4-(N-morpholinylmethyl)phenyl]-1H-pyrrolo[2,3-b]-pyridine | Drug Info |
| AuroraA --- STK1 | (Z)-3-(4-Oxo-2-{[2-oxo-5-(pyrrolidin-1-ylsulfonyl)indolin-3-ylidene]methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic Acid | Drug Info |
| AuroraA --- STK1 | (Z)-Ethyl 3-(4-Oxo-2-{[2-oxo-5-(phenylsulfonamido)indolin-3-ylidene]methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoate | Drug Info |
| AuroraA --- STK1 | (Z)-3-(2-{[5-(Morpholinosulfonyl)-2-oxoindolin-3-ylidene]-methyl}-4-oxo-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic Acid | Drug Info |
| AuroraA --- STK1 | 4-[1-Ethyl-3-(4-{[(phenylamino)carbonyl]amino}phenyl)-1Hpyrazol-4-yl]-N-[2-(4-methyl-1-piperazinyl)ethyl]-1H-pyrrolo-[2,3-b]pyridine-2-carboxamide | Drug Info |
| B1R --- B2R | Lys-Lys-[deltaPhe7] Bradykinin | Drug Info |
| Beta PDGFR --- CD135 | (1H-indol-2-yl)(6-methoxy-1H-indol-2-yl)methanone | Drug Info |
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