Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CDK1 --- CDK4 | R547 | Drug Info |
| Beta PDGFR --- CD135 | (4-Methyl-1H-indol-2-yl)-[5-(2-piperidin-1-yl-ethoxy)-1H-indol-2-yl]-methanone | Drug Info |
| BNOS --- Hepatocyte NOS | 5-Ethyl-4-methyl-pyrrolidin-(2Z)-ylideneamine | Drug Info |
| BNOS --- Hepatocyte NOS | 7,8-Difluoro-4-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-quinolin-2(1H)-one | Drug Info |
| BNOS --- Hepatocyte NOS | [1,4]Thiazepan-(3E)-ylideneamine | Drug Info |
| BNOS --- Hepatocyte NOS | 3-(2-Amino-ethyl)-5-imino-[1,4]oxazepane | Drug Info |
| BNOS --- Hepatocyte NOS | CHEMBL1221702 | Drug Info |
| BNOS --- Hepatocyte NOS | 3-Ethyl-azepan-(2Z)-ylideneamine; hydrochloride | Drug Info |
| BNOS --- Hepatocyte NOS | 4-chloro-2-((ethyl(piperidin-4-yl)amino)methyl)benzonitrile | Drug Info |
| BNOS --- Hepatocyte NOS | 4-(((3-chlorophenyl)(6-methoxypyrimidin-4-yl)amino)methyl)-7,8-difluoroquinolin-2(1H)-one | Drug Info |
| BNOS --- Hepatocyte NOS | 1-(2-(2-(1H-imidazol-1-yl)-6-methylpyrimidin-4-yl)pyrrolidin-1-yl)-2-(benzo[d][1,3]dioxol-5-ylmethylamino)ethanone | Drug Info |
| CABL --- Ckit | 4-(chloromethyl)-N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)benzamide | Drug Info |
| 5HT1a --- SERT | (S)-1-(1H-Indol-4-yloxy)-3-[4-(3-methyl-benzo[b]thiophen-2-yl)-piperidin-1-yl]-propan-2-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-[(4S,6R)-4-(6-Chloro-benzo[b]thiophen-2-yl)-2-methyl-piperidin-1-yl]-3-(1H-indol-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-[4-(6-Chloro-benzo[b]thiophen-2-yl)-piperidin-1-yl]-3-(1H-indol-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1b --- SERT | (2-(4-(trifluoromethoxy)benzyl)phenyl)-N,N-dimethylmethanamine | Drug Info |
| AChE --- NMDA | CHEMBL1199290 | Drug Info |
| ADRA1A --- HRH1 | 5-Methoxy-3-{4-[4-(4-methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole | Drug Info |
| ADRA1A --- HRH1 | 2-{2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethoxy}-ethanol | Drug Info |
| ADRA1A --- HRH1 | 4-(4-chlorobenzyl)-2-(2-(1-methylpyrrolidin-2-yl)ethyl)phthalazin-1(2H)-one | Drug Info |
| CABL --- FGFR1 | PD-0173956 | Drug Info |
| CABL --- VEGFR1 | NVP-TAE684 | Drug Info |
| Aurora --- GSK | 3-(4-(3-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-ylamino)phenyl)acrylic acid | Drug Info |
| AuroraA --- CDK4 | N-4-4-methylpiperazin-1-yl-phenyl-7-pyridin-3-yl-7H-pyrrolo[2,3-d]pyrimidin-2-amine | Drug Info |
| AuroraA --- STK1 | 3-methyl-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | 2-phenyl-N-(3-(2-phenylcyclopropyl)-1H-indazol-5-yl)acetamide | Drug Info |
| AuroraA --- STK1 | CHEMBL215203 | Drug Info |
| AuroraA --- STK1 | N-(6-methyl-3-(3-((4-methylpiperazin-1-yl)methyl)styryl)-1H-indazol-5-yl)-2-(thiophen-2-yl)acetamide | Drug Info |
| AuroraA --- STK1 | 4-[3-(4-N,N-Dimethylcarbamylaminophenyl)-1-ethyl-1H-pyrazol-4-yl]-2-[4-(dimethylaminomethyl)phenyl]-1H-pyrrolo[2,3-b]-pyridine | Drug Info |
| AuroraA --- STK1 | N-(4-(benzo[d]thiazol-2-yl)phenyl)thieno[3,2-d]pyrimidin-4-amine | Drug Info |
| AuroraA --- STK1 | (Z)-3-({3-[3-(Diethylamino)propyl]-4-oxo-4,5,6,7-tetrahydro-1H-indol-2-yl}methylene)-5-(indolin-1-ylsulfonyl)indolin-2-one | Drug Info |
| AuroraA --- STK1 | 3-((2,2-dimethylmorpholino)methyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine | Drug Info |
| Beta PDGFR --- CABL | 4-chloro-N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)benzamide | Drug Info |
| Beta PDGFR --- Ckit | 4-[6-Methoxy-7-(3-piperidin-1-yl-propoxy)-quinazolin-4-yl]-piperazine-1-carbothioic acid (5-methyl-pyrazin-2-ylmethyl)-amide | Drug Info |
| BNOS --- Hepatocyte NOS | 4-(6-(4-(4-(((2R,4S)-2-((1H-1,2,4-triazol-1-yl)methyl)-2-(2,4-difluorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)pyridin-3-yl)-1-(1-hydroxypropan-2-yl)-1H-1,2,4-triazol-5(4H)-one | Drug Info |
| BNOS --- Hepatocyte NOS | 2-((3-(1H-imidazol-1-yl)-1,2,4-thiadiazol-5-yl)(3-(benzo[d][1,3]dioxol-5-ylmethylamino)propyl)amino)-N-methylacetamide | Drug Info |
| BNOS --- Hepatocyte NOS | 4-(((3-chlorophenyl)(pyrimidin-4-yl)amino)methyl)-7,8-difluoroquinolin-2(1H)-one | Drug Info |
| BNOS --- Hepatocyte NOS | 4-methyl-6-propylpyridin-2-amine | Drug Info |
| BNOS --- Hepatocyte NOS | 2-pyridinamine | Drug Info |
| BNOS --- Hepatocyte NOS | 4-Methoxy-pyridin-2-ylamine | Drug Info |
| BNOS --- Hepatocyte NOS | 4-(((3-chlorophenyl)(pyridin-4-yl)amino)methyl)-7,8-difluoroquinolin-2(1H)-one | Drug Info |
| BNOS --- Hepatocyte NOS | N1-(3-(1H-imidazol-1-yl)-1,2,4-thiadiazol-5-yl)-N3-(benzo[d][1,3]dioxol-5-ylmethyl)-N1-(pyridin-3-ylmethyl)propane-1,3-diamine | Drug Info |
| BNOS --- Hepatocyte NOS | 2-(2-Amino-ethyl)-7-imino-azepane | Drug Info |
| CAI --- CAIX | 4,6-Dimethyl-2H-pyran-2-thione | Drug Info |
| 5HT1a --- SERT | 3-(4-(4-fluorophenyl)piperazin-1-yl)-1-phenylpropan-1-ol | Drug Info |
| 5HT1a --- SERT | 2-{1-[(S)-2-Hydroxy-3-(1H-indol-4-yloxy)-propyl]-piperidin-4-yl}-benzo[b]thiophen-7-ol | Drug Info |
| 5HT1a --- SERT | 6-{1-[2-(Isoquinolin-1-yloxy)-ethyl]-piperidin-4-yloxy}-4H-benzo[1,4]oxazin-3-one | Drug Info |
| 5HT1b --- SERT | (-)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate | Drug Info |
| 5LOX --- HRH1 | [4-((2S,5S)-5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-ylmethyl}-tetrahydro-furan-2-yl)-but-3-ynyl]-N-hydroxyurea | Drug Info |
| ADRA1A --- HRH1 | Methyl-(2,3,3a,8-tetrahydro-1-oxa-12b-aza-dibenzo[e,h]azulen-2-ylmethyl)-amine | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.