Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| BNOS --- Hepatocyte NOS | SID11111545 | Drug Info |
| BNOS --- Hepatocyte NOS | 6-butyl-2-(2-(4-methoxypyridin-2-yl)ethyl)-3H-imidazo[4,5-b]pyridine | Drug Info |
| BNOS --- Hepatocyte NOS | (E)-8-Propyl-3,4,5,6,7,8-hexahydro-azocin-2-ylamine | Drug Info |
| BNOS --- Hepatocyte NOS | CHEMBL59925 | Drug Info |
| BNOS --- Hepatocyte NOS | 4-((2-Cyclopentyl-1H-imidazo[4,5-b]pyrazin-1-yl)methyl)-7,8-difluoroquinolin-2(1H)-one | Drug Info |
| BNOS --- Hepatocyte NOS | Ng-METHYL-L-ARGININE ACETATE | Drug Info |
| BNOS --- Hepatocyte NOS | N-(3-Aminomethyl-phenyl)-thiophene-2-carboxamidine | Drug Info |
| CAI --- CAIX | potassium(E)-5-hydroxy-2-pentenoic acid | Drug Info |
| 5HT1a --- SERT | 1-phenyl-3-(4-(pyrimidin-2-yl)piperazin-1-yl)propan-1-ol | Drug Info |
| 5HT1a --- SERT | [2-(5-Fluoro-2-methoxy-phenoxy)-ethyl]-[2-(1H-indol-3-yl)-ethyl]-amine | Drug Info |
| 5HT1a --- SERT | (S)-1-(1H-Indol-4-yloxy)-3-[4-(4-isopropoxy-benzo[b]thiophen-2-yl)-piperidin-1-yl]-propan-2-ol | Drug Info |
| 5HT1b --- SERT | N-[3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]-N-methylamine | Drug Info |
| AChE --- NMDA | SID124882535 | Drug Info |
| ADRA1A --- HRH1 | N-((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-ylamino)cyclohexyl)-3-methylbenzamide | Drug Info |
| ADRA1A --- HRH1 | 7-[3-(4-Benzhydryl-piperidin-1-yl)-propyl]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione; compound with (E)-but-2-enedioic acid | Drug Info |
| ADRA1A --- HRH1 | 2,8-dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole | Drug Info |
| CABL --- Ckit | Sunitinib | Drug Info |
| CABL --- TEK | WYE-130600 | Drug Info |
| Aurora --- GSK | 4-[4-(3-Hydroxy-adamantan-1-ylamino)-5-nitro-pyrimidin-2-ylamino]-benzoic acid | Drug Info |
| AuroraA --- CDK4 | N-4-4-methylpiperazin-1-yl-phenyl-7-3-methylsulfonyl-phenyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine | Drug Info |
| AuroraA --- STK1 | PHA-680632 | Drug Info |
| AuroraA --- STK1 | 1-phenyl-3-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)urea | Drug Info |
| AuroraA --- STK1 | N-(3-fluorophenyl)-2-{2-[(7-{3-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]propoxy}-6-methoxyquinazolin-4-yl)amino]-1,3-thiazol-5-yl}acetamide | Drug Info |
| AuroraA --- STK1 | 2-[3-(4-{[(Phenylamino)carbonyl]amino}phenyl)-4-(1H-pyrrolo-[2,3-b]pyridin-4-yl)-1H-pyrazol-1-yl]acetamide | Drug Info |
| AuroraA --- STK1 | 1-(4-((5-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-ylamino)isothiazol-3-yl)methyl)piperazin-1-yl)ethanone | Drug Info |
| AuroraA --- STK1 | CHEMBL214849 | Drug Info |
| AuroraA --- STK1 | 1-(3-fluorophenyl)-3-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)urea | Drug Info |
| B-Raf --- VEGFR | 3,3-Dimethyl-6-(6-methyl-5-(2-(methylamino)quinazolin-6-yl)isoquinolin-1-ylamino)indolin-2-one | Drug Info |
| Beta PDGFR --- CABL | 1-(3-Chloro-phenyl)-3-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-urea | Drug Info |
| BNOS --- Hepatocyte NOS | N1-(3-(1H-imidazol-1-yl)-1,2,4-thiadiazol-5-yl)-N3-(benzo[d][1,3]dioxol-5-ylmethyl)-N1-(4-(dimethylamino)benzyl)propane-1,3-diamine | Drug Info |
| BNOS --- Hepatocyte NOS | (5S,6S)-[Octahydro-quinolin-(2E)-ylidene]amine | Drug Info |
| BNOS --- Hepatocyte NOS | 5-Ethyl-4-methyl-pyrrolidin-(2E)-ylideneamine; hydrochloride | Drug Info |
| BNOS --- Hepatocyte NOS | 4-chloro-2-(((1-isopentylpiperidin-4-yl)(methyl)amino)methyl)benzonitrile | Drug Info |
| BNOS --- Hepatocyte NOS | (3aS,9bR)-3a-Fluoro-7-(2-methylamino-ethyl)-2,3,3a,9b-tetrahydro-1H-cyclopenta[c]quinolin-4-ylamine | Drug Info |
| BNOS --- Hepatocyte NOS | (5-Imino-[1,4]thiazepan-3-yl)-methanol | Drug Info |
| BNOS --- Hepatocyte NOS | [1,4]Oxazepan-(3E)-ylideneamine | Drug Info |
| BNOS --- Hepatocyte NOS | CHEMBL1194759 | Drug Info |
| BNOS --- Hepatocyte NOS | 3-(2-Nitro-ethyl)-[1,4]oxazepan-(5Z)-ylideneamine | Drug Info |
| BNOS --- Hepatocyte NOS | 6-Methyl-piperidin-(2Z)-ylideneamine | Drug Info |
| CAI --- CAIX | sodium azide | Drug Info |
| 5HT1a --- SERT | [3-(5-Fluoro-1H-indol-2-yl)-propyl]-(2-phenoxy-ethyl)-amine | Drug Info |
| 5HT1a --- SERT | (S)-1-[(4S,6R)-4-(4,5-Dimethoxy-benzo[b]thiophen-2-yl)-2-methyl-piperidin-1-yl]-3-(1H-indol-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1a --- SERT | 2-methyl-5-(2-(4-((3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)methyl)piperidin-1-yl)ethoxy)quinoline-7-carbonitrile | Drug Info |
| 5HT1a --- SERT | [2-(5-Fluoro-benzofuran-7-yloxy)-ethyl]-[3-(5-fluoro-1H-indol-3-yl)-propyl]-amine | Drug Info |
| 5LOX --- HRH1 | 1-{4-[4-(3-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}propoxy)phenyl]but-3-yn-1-yl}-1-hydroxyurea | Drug Info |
| ADRA1A --- HRH1 | methyl 1-(3-(5-(ethylcarbamoyl)-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3-carboxamido)propyl)-4-phenylpiperidine-4-carboxylate | Drug Info |
| ADRA1A --- HRH1 | 2-(4-Dimethylamino-phenyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid {2-hydroxy-3-[4-(2-isopropoxy-phenyl)-piperazin-1-yl]-propyl}-amide | Drug Info |
| ADRA1A --- HRH1 | 4-{[4-(Ethyloxy)phenyl]methyl}-2-{[(2R)-1-methyl-2-pyrrolidinyl]methyl}-1(2H)-phthalazinone | Drug Info |
| CABL --- CD135 | (5-hydroxy-1H-indol-2-yl)(1H-indol-2-yl)methanone | Drug Info |
| CABL --- FGFR1 | PD-0173955 | Drug Info |
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