Multi-target agents
Target Pair | Drug Name | |
---|---|---|
Cathepsin K --- MEP | benzyl (S)-1-oxo-1-((3R,4R)-2-oxo-4-phenoxyazetidin-3-ylamino)-3-phenylpropan-2-ylcarbamate | Drug Info |
Cathepsin K --- MEP | (S)-N-((S)-1-(5-(furan-2-yl)-1,3,4-oxadiazol-2-yl)-1-oxopentan-2-yl)-4-methyl-2-(2,2,2-trifluoroethylamino)pentanamide | Drug Info |
Cathepsin K --- MEP | (R)-2-{3'-[2-(4-tert-butyl-piperazin-1-yl)-thiazol-4-yl]-biphenyl-3-yl}-4-methyl-pentanoic acid cyanomethyl-amide | Drug Info |
Cathepsin K --- MEP | N-((S)-3-cyclohexyl-1-((S)-1-(5-fluoroindolin-1-yl)propan-2-ylamino)-1-oxopropan-2-yl)morpholine-4-carboxamide | Drug Info |
Cathepsin K --- MEP | 2',3',4'-trifluoro-biphenyl-2-yloxy-acetaldehyde | Drug Info |
CCKBR --- CCKAR | N-tert-Butyl-2-{(3R,5R)-3-[3-(3-chloro-phenyl)-ureido]-7-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-acetamide | Drug Info |
CCKBR --- CCKAR | 3-(2-Amino-3-naphthalen-1-yl-propionylamino)-N-({[1-tert-butoxycarbonyl-2-(1H-indol-3-yl)-ethyl]-methyl-carbamoyl}-cyclohexyl-methyl)-succinamic acid | Drug Info |
CCKBR --- CCKAR | (S)-2-(2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-4-chlorobenzamido)-3-(4-chlorophenyl)-3-methylbutanoic acid | Drug Info |
CCKBR --- CCKAR | N-tert-Butyl-2-{(3R,5S,7R)-2-oxo-7-phenyl-5-o-tolyl-3-[3-(3-trifluoromethyl-phenyl)-ureido]-azepan-1-yl}-acetamide | Drug Info |
CCKBR --- CCKAR | N-tert-Butyl-2-((3R,5S)-5-cyclohexylmethyl-8-methyl-2-oxo-3-{3-[3-(1H-tetrazol-5-yl)-phenyl]-ureido}-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl)-acetamide | Drug Info |
CCKBR --- CCKAR | 2-[(3R,5S,7R)-2-Oxo-7-phenyl-5-o-tolyl-3-(3-m-tolyl-ureido)-azepan-1-yl]-N-o-tolyl-acetamide | Drug Info |
CCKBR --- CCKAR | 3-{5-tert-Butoxycarbonylamino-2-[2-tert-butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-pentanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid | Drug Info |
CCKBR --- CCKAR | CCK7 analogue | Drug Info |
CCKBR --- CCKAR | [2-(4-Benzoyl-piperidin-1-yl)-1-(1H-indol-3-ylmethyl)-1-methyl-2-oxo-ethyl]-carbamic acid adamantan-2-yl ester | Drug Info |
CCKBR --- CCKAR | 1H-Indole-2-carboxylic acid [5-(2-fluoro-phenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-amide | Drug Info |
CCKBR --- CCKAR | Tyr-D-Phe-Gly-Trp-Nle-Asp-Phe-NH2 | Drug Info |
CD135 --- Ckit | (4-(5-amino-1-(pyridin-2-yl)-1H-1,2,4-triazol-3-ylamino)phenyl)(morpholino)methanone | Drug Info |
CD221 --- JNK1 | 2-(2-(1-(2-(dimethylamino)ethyl)-5-methoxyindolin-6-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-6-fluorobenzamide | Drug Info |
CDK1 --- CDK2 | 4-((2-oxo-2,3-dihydropyrrolo[3,2-f]quinolin-1-ylidene)methylamino)benzenesulfonamide | Drug Info |
CDK1 --- CDK2 | 3-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-benzenesulfonamide | Drug Info |
CDK1 --- GSK3 | Thieno analogue of kenpaullone | Drug Info |
CDK1 --- GSK3 | 2-((E)-3-oxo-but-1-enyl)-9-trifluoromethyl-5,12-dihydro-7H-benzo[2,3]azepino[4,5-b]indol-6-one | Drug Info |
CDK1 --- GSK3 | (9-Bromo-6-oxo-6,7-dihydro-12H-benzo[2,3]azepino[4,5-b]indol-5-yl)-acetic acid methyl ester | Drug Info |
CDK1 --- VEGFR | 3-{4-[6-(3-Chloro-phenylamino)-pyrazin-2-yl]-pyridin-2-ylamino}-propan-1-ol | Drug Info |
CDK2 --- AKT | (S)-N1-(5-(isoquinolin-6-yl)-1,3,4-thiadiazol-2-yl)-3-(4-(trifluoromethyl)phenyl)propane-1,2-diamine | Drug Info |
CDK2 --- AuroraA | N,1,4,4-Tetramethyl-8-({3-[(4-methylpiperazin-1-yl)methyl]-phenyl}amino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
CDK2 --- AuroraA | N,1,4,4-Tetramethyl-8-({3-[(1-methylpiperidin-4-yl)oxy]phenyl}-amino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
CDK2 --- CDK1 | GW416981X | Drug Info |
CDK2 --- CDK1 | (Z)-4-(2-(5-methoxy-2-oxoindolin-3-ylidene)hydrazinyl)benzenesulfonamide | Drug Info |
CDK2 --- CDK1 | 4-(5-(diethylamino)-[1,2,4]triazolo[1,5-a]pyrimidin-7-ylamino)benzenesulfonamide | Drug Info |
CDK2 --- CDK1 | (3-Chloro-phenyl)-(6-cyclohexylmethoxy-9H-purin-2-yl)-amine | Drug Info |
CDK2 --- CDK1 | (6-Cyclohexylmethoxy-9H-purin-2-yl)-ethyl-amine | Drug Info |
CDK2 --- CDK1 | 4-(4-amino-6-(cyclohexylmethoxy)pyrimidin-2-ylamino)benzenesulfonamide | Drug Info |
CDK2 --- CDK4 | (4Z)-6-Bromo-4-({[(2-oxo-1,2-dihydropyridin-4-yl)methyl]amino}methylene) isoquinoline-1,3(2H,4H)-dione | Drug Info |
CDK2 --- CDK4 | 3,5-Dimethyl-4-[2-(4-methyl-3-nitro-phenylamino)-pyrimidin-4-yl]-1H-pyrrole-2-carbonitrile | Drug Info |
CDK2 --- CDK4 | CHEMBL515839 | Drug Info |
CDK2 --- CDK4 | (3,5-Dichloro-phenyl)-(4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-yl)-amine | Drug Info |
CDK2 --- CSrc | 3-(4-(4-(hydroxymethyl)thiazol-2-yl)pyrimidin-2-ylamino)-5-(trifluoromethyl)phenol | Drug Info |
CDK2 --- Cyclin E | 2-{(2-Hydroxy-ethyl)-[9-isopropyl-6-(4-thiophen-2-yl-benzylamino)-9H-purin-2-yl]-amino}-ethanol | Drug Info |
CDK2 --- Cyclin E | 5-(2-chlorophenyl)-7-nitro-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine | Drug Info |
CDK2 --- Cyclin E | N-[5-(Pyridin-3-ylmethylsulfanyl)-thiazol-2-yl]-acetamide | Drug Info |
CDK2 --- Cyclin E | N-[5-(2-tert-Butoxy-ethylsulfanyl)-thiazol-2-yl]-acetamide | Drug Info |
CDK2 --- Cyclin E | N-[5-(2-tert-Butyl-oxazol-5-ylmethylsulfanyl)-thiazol-2-yl]-2-phenyl-acetamide | Drug Info |
CDK2 --- Cyclin E | 5-Benzenesulfinyl-4-butoxy-1H-pyrazolo[3,4-b]pyridine | Drug Info |
CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((2-phenylthiazol-5-yl)methyl)-9H-purine-2,6-diamine hydrochloride | Drug Info |
CDK2 --- GSK3 | SID49815772 | Drug Info |
CAII --- CAI | N-(2-fluorobenzylidene)(4-sulfonamidephenyl)ethanamine | Drug Info |
CDK4 --- Cyclin E | 5-[5-(3-Morpholin-4-yl-ureido)-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-3-yl]-thiophene-2-carboxylic acid (2-dimethylamino-ethyl)-amide | Drug Info |
CAII --- CAI | N-[5-(methylsulfonyl)-1,3,4-thiadiazol-2-yl]sulfamide | Drug Info |
Ckit --- BRaf | 1-(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carbamoyl)phenylamino)methyl)pyridin-2-yl)-3-phenylurea | Drug Info |
Pagination
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