Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CDK2 --- Cyclin E | N-[5-(Pyridin-3-ylmethylsulfanyl)-thiazol-2-yl]-acetamide | Drug Info |
| CDK2 --- Cyclin E | N-[5-(2-tert-Butoxy-ethylsulfanyl)-thiazol-2-yl]-acetamide | Drug Info |
| CDK2 --- Cyclin E | N-[5-(2-tert-Butyl-oxazol-5-ylmethylsulfanyl)-thiazol-2-yl]-2-phenyl-acetamide | Drug Info |
| CDK2 --- Cyclin E | 5-Benzenesulfinyl-4-butoxy-1H-pyrazolo[3,4-b]pyridine | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((2-phenylthiazol-5-yl)methyl)-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- GSK3 | SID49815772 | Drug Info |
| CAII --- CAI | N-(2-fluorobenzylidene)(4-sulfonamidephenyl)ethanamine | Drug Info |
| CDK4 --- Cyclin E | 5-[5-(3-Morpholin-4-yl-ureido)-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-3-yl]-thiophene-2-carboxylic acid (2-dimethylamino-ethyl)-amide | Drug Info |
| CAII --- CAI | N-[5-(methylsulfonyl)-1,3,4-thiadiazol-2-yl]sulfamide | Drug Info |
| Ckit --- BRaf | 1-(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carbamoyl)phenylamino)methyl)pyridin-2-yl)-3-phenylurea | Drug Info |
| CAII --- CAI | 2-Amino-N-{[4-(3-sulfamoyl-phenylsulfamoyl)-phenylcarbamoyl]-methyl}-acetamide | Drug Info |
| COX2 --- 5LOX | 3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl)-1-(4-(methylsulfonyl)phenyl)-5-phenyl-1H-pyrazole | Drug Info |
| CAII --- CAI | (S)-4-Methyl-2-[3-(4-sulfamoyl-phenyl)-thioureido]-pentanoic acid methylcarbamoylmethyl with resin | Drug Info |
| COX2 --- 5LOX | 3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)phenoxymethyl]-1-(4-methylphenyl)-5-phenyl-1H-pyrazole | Drug Info |
| CAII --- CAI | 2-(4-Sulfamoyl-benzoylamino)-succinamic acid | Drug Info |
| COX2 --- 5LOX | 2,6-Dimethyl-4-(2-thiophen-2-yl-vinyl)-phenol | Drug Info |
| CAII --- CAI | Aminobenzoate Sodium | Drug Info |
| CSrc --- CABL | N-(5-(4-bromobenzylthio)-1,3,4-thiadiazol-2-yl)-4-fluorobenzamide | Drug Info |
| CAII --- CAI | 2-(N-Methyl-guanidino)-N-[4-(4-sulfamoyl-phenylsulfamoyl)-phenyl]-acetamide | Drug Info |
| CSrc --- CABL | 1-(2-chloro-2-phenylethyl)-N,N-dimethyl-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-6-amine | Drug Info |
| CAII --- CAI | (R)-4-((8S,10S,12S,14R,15R,17S)-10,13-Dimethyl-3,7,12-trioxo-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid (2-sulfamoyl-benzothiazol-6-yl)-amide | Drug Info |
| CSrc --- CABL | 1-(2-bromo-2-phenylethyl)-6-(methylthio)-4-(pyrrolidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine | Drug Info |
| CAII --- CAI | 2-[(1E)-{[2-(4-sulfamoylphenyl)ethyl]imino}methyl]phenyl N-[(4-methylbenzene)sulfonyl]carbamate | Drug Info |
| CSrc --- CABL | (E)-3-(2-(Purin-9-yl)vinyl)-4-methyl-N-(4-(trifluoromethyl)pyridin-2-yl)benzamide | Drug Info |
| CAII --- CAI | 3-Bromo-4-(5,7-dioxo-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-benzenesulfonamide | Drug Info |
| CSrc --- CABL | N-(5-(3-chlorobenzylthio)-1,3,4-thiadiazol-2-yl)-4-fluorobenzamide | Drug Info |
| CAII --- CAI | 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-Heptadecafluoro-octane-1-sulfonic acid 2-sulfamoyl-benzothiazol-6-yl ester | Drug Info |
| CSrc --- Ckit | 3-(2-aminoquinazolin-6-yl)-1-(3-methoxyphenyl)-4-methylpyridin-2(1H)-one | Drug Info |
| CAII --- CAI | (1R,2R,5R)-4-((1R,5S,8S,10R,11S,12S)-3,12-Dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid (2,3-dichloro-4,6-disulfamoyl-phenyl)-amide | Drug Info |
| DHFR --- TYMS | 2-Amino-6-ethyl-5-(pyridin-4-ylsulfanyl)thieno[2,3-d]pyrimidin-4(3H)-one | Drug Info |
| CAII --- CAI | 1-(3-(4-bromophenyl)-5-sulfamoyl-1H-indole-2-carboxamido)-2,4,6-trimethylpyridinium perchlorate | Drug Info |
| DHFR --- TYMS | 2-Amino-6-ethyl-5-[(4-nitrophenyl)sulfanyl]thieno[2,3-d]pyrimidin-4(3H)-one | Drug Info |
| CAII --- CAI | 3-Chloro-4-(3-pentafluorophenyl-ureido)-benzenesulfonamide | Drug Info |
| EGFR --- HER2 | 3-(3,4-dihydroxyphenyl)-2-(4-fluorobenzoyl)acrylonitrile | Drug Info |
| CAII --- CAI | 2,6-Dimethyl-4-phenyl-1-(2-sulfamoyl-benzothiazol-6-yloxycarbonylmethyl)-pyridinium; perchlorate | Drug Info |
| EGFR3 --- CABL | (5,6-Dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-phenyl-amine | Drug Info |
| CAII --- CAI | N,N-dialkylthio-carbonylsulfenylamino derivative | Drug Info |
| EGFR3 --- CSrc | 3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-one | Drug Info |
| CAII --- CAI | N-hydroxy-4-methoxybenzamide | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-5-(5-morpholinopent-1-ynyl)pyrimidin-4-amine | Drug Info |
| CAII --- CAI | 2-(N-Methyl-guanidino)-N-(5-sulfamoyl-[1,3,4]thiadiazol-2-yl)-acetamide | Drug Info |
| EGFR3 --- HER2 | 4-(Bis(2-chloroethyl)amino)-N-(4-fluorophenyl)benzamide | Drug Info |
| CAII --- CAI | 4-Methyl-5-[4-(nonafluorobutane-1-sulfonylamino)-benzenesulfonylimino]-4,5-dihydro-[1,3,4]thiadiazole-2-sulfonic acid amide | Drug Info |
| EGFR3 --- HER2 | 2-(5-(4-Fluorophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one | Drug Info |
| CAII --- CAI | 2,6-Dimethyl-4-phenyl-1-{[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-methyl}-pyridinium; perchlorate | Drug Info |
| EGFR3 --- HER2 | 1,4-Dihydroxy-5-(2-(2-aminoethylamino)ethylamino)-8-(2-(2-hydroxyethylamino)ethylamino)anthracene-9,10-dione | Drug Info |
| CAII --- CAI | {{2-[2-(2-{Carboxymethyl-[N'-(4-sulfamoyl-phenyl)-hydrazinocarbonylmethyl]-amino}-ethoxy)-ethoxy]-ethyl}-[N'-(4-sulfamoyl-phenyl)-hydrazinocarbonylmethyl]-amino}-acetic acid | Drug Info |
| EGFR3 --- HER2 | 4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-3-methyl-N-(2-morpholinoethyl)-1H-pyrrolo[3,2-d]pyridazine-2-carboxamide | Drug Info |
| CAII --- CAI | {(2-{Carboxymethyl-[(2-iodo-4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-ethyl)-[(2-iodo-4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-acetic acid | Drug Info |
| EGFR3 --- HER2 | 4-Benzylcarbamoyl-butyric acid 4-((E)-2-nitro-vinyl)-phenyl ester | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.