Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CCKBR --- CCKAR | (S)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-[(S)-2-((S)-3-1H-indol-3-yl-2-isopropoxycarbonylamino-propionylamino)-6-(3-o-tolyl-ureido)-hexanoylamino]-N-methyl-succinamic acid | Drug Info |
| CCKBR --- CCKAR | H-Tyr-D-Ala-Gly-Phe-NH-NH-(NMe)Phe-Asp-Lys(Cpac)-Trp-Ac | Drug Info |
| CCKBR --- CCKAR | N-tert-Butyl-2-[(3R,5S,7R)-5-(2-ethyl-phenyl)-2-oxo-7-phenyl-3-(3-m-tolyl-ureido)-azepan-1-yl]-acetamide | Drug Info |
| CCKBR --- CCKAR | N-{1-[1-[({2-[2-tert-Butoxycarbonylamino-3-(4-sulfooxy-phenyl)-propionylamino]-hexanoylamino}-methyl)-carbamoyl]-2-(1H-indol-3-yl)-ethylcarbamoyl]-pentyl}-3-(3-phenyl-propionylamino)-succinamic acid | Drug Info |
| CCKBR --- CCKAR | 1-[(S)-2-(4-Benzoyl-piperidin-1-yl)-1-benzylsulfanylmethyl-2-oxo-ethyl]-3-m-tolyl-urea | Drug Info |
| CCKBR --- CCKAR | 1-[(S)-2-(4-Benzoyl-piperidin-1-yl)-2-oxo-1-phenylmethanesulfinylmethyl-ethyl]-3-m-tolyl-urea | Drug Info |
| CCKBR --- CCKAR | N-tert-Butyl-2-[(3R,5S,7R)-2-oxo-5-phenyl-7-m-tolyl-3-(3-m-tolyl-ureido)-azepan-1-yl]-acetamide | Drug Info |
| CCKBR --- CCKAR | (R)-4-{[(Isopropyl-phenyl-carbamoyl)-methyl]-phenyl-carbamoyl}-4-(3-phenyl-ureido)-butyric acid | Drug Info |
| CCKBR --- CCKAR | Boc-Tyr(So3-)-Met-Gly-Trp-Nle-Asp-psi(CH2NH)-Phe-NH2 | Drug Info |
| CCKBR --- CCKAR | N-(1-Carbamoyl-2-phenyl-ethyl)-3-{[(2R,5S)-2-(1H-indol-3-ylmethyl)-2-methyl-3,13-dioxo-1,4diaza-cyclotridecane-5-carbonyl]-amino}-succinamic acid | Drug Info |
| CCKBR --- CCKAR | 3-{6-(3-Benzyl-ureido)-2-[2-tert-butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid | Drug Info |
| CD135 --- Ckit | N-(4-(5-amino-1-(pyridin-2-yl)-1H-1,2,4-triazol-3-ylamino)phenyl)acetamide | Drug Info |
| CD221 --- STK1 | SID137275914 | Drug Info |
| CDK1 --- CDK2 | 4-(2-(4-chloro-5-methoxy-2-oxoindolin-3-ylidene)hydrazinyl)benzenesulfonamide | Drug Info |
| CDK1 --- CDK4 | 6-Benzylamino-2-[(1R,2RS)-1-ethyl-2-hydroxypropylamino]-9-isopropylpurine | Drug Info |
| CDK1 --- GSK3 | 7-Cyclopropylmethyl-6-(4-methoxy-phenyl)-5H-pyrrolo[2,3-b]pyrazine | Drug Info |
| CDK1 --- GSK3 | 3-(6-Oxo-9-trifluoromethyl-5,6,7,12-tetrahydro-benzo[2,3]azepino[4,5-b]indol-2-yl)-propionitrile | Drug Info |
| CDK1 --- HER2 | N-methyl(5-(3-(5-(trifluoromethoxy)-1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl)pyridin-3-yl)methanamine | Drug Info |
| CDK2 --- AKT | (2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl)((S)-3-aminopyrrolidin-1-yl)methanone | Drug Info |
| CDK2 --- AuroraA | N-cyclopropyl-1-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | 8-{[3-(Dimethylamino)phenyl]amino}-N,1,4,4-tetramethyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- CD221 | CHEMBL1809194 | Drug Info |
| CDK2 --- CDK1 | 4-[6-Amino-5-(2,6-difluoro-benzoyl)-pyridin-2-ylamino]-N,N-dimethyl-benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | (Z)-4-(2-(2-oxo-4-phenoxyindolin-3-ylidene)hydrazinyl)benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | SID124349847 | Drug Info |
| CDK2 --- CDK1 | N-(2-{2-[2-(2-Methoxy-ethoxy)-ethoxy]-ethoxy}-ethyl)-4-[(7-oxo-6,7-dihydro-thiazolo[5,4-e]indol-8-ylidenemethyl)-amino]-benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | 6-Cyclohexylmethoxy-N*2*-(4-methoxy-phenyl)-5-nitroso-pyrimidine-2,4-diamine | Drug Info |
| CDK2 --- CDK1 | GW300660X | Drug Info |
| CDK2 --- CDK4 | 4-[2-(3-Hydroxy-phenylamino)-pyrimidin-4-yl]-3,5-dimethyl-1H-pyrrole-2-carbonitrile | Drug Info |
| CDK2 --- CDK4 | TCMDC-138697 | Drug Info |
| CDK2 --- CDK4 | CHEMBL317629 | Drug Info |
| CDK2 --- CDK4 | CHEMBL478409 | Drug Info |
| CDK2 --- Cyclin E | 2-[9-Isopropyl-6-(4-methoxy-benzylamino)-9H-purin-2-ylamino]-ethanol | Drug Info |
| CDK2 --- Cyclin E | 6-Benzyl-3-methylsulfanyl-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
| CDK2 --- Cyclin E | 2-[9-Isopropyl-6-(4-methoxy-benzylamino)-9H-purin-2-ylamino]-3-phenyl-propan-1-ol | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((5-(4-methylthiazol-2-yl)thiophen-2-yl)methyl)-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | 3-Ethyl-6-(2-methoxy-benzyl)-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
| CDK2 --- Cyclin E | 4-((3,5-Diamino-1H-pyrazol-4-yl)diazenyl)phenol | Drug Info |
| CDK2 --- Cyclin E | 5-(2-chlorophenyl)-7-nitro-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine-3-carboxamide | Drug Info |
| CDK2 --- GSK3 | 3-[2-(3-Trifluoromethyl-phenylamino)-pyrimidin-4-yl]-pyrazolo[1,5-b]pyridazin-6-ol | Drug Info |
| CAII --- CAI | (Carboxymethyl-{[2-(5-sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-ethylcarbamoyl]-methyl}-amino)-acetic acid | Drug Info |
| CDK4 --- Cyclin E | ethyl 5-(5-{[(2,2-dimethylhydrazino)carbonyl]amino}-4-oxo-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophene-2-carboxylate | Drug Info |
| CAII --- CAI | N-(5-Chloro-2,4-disulfamoyl-phenyl)-2-methylamino-acetamide | Drug Info |
| Chk --- VEGFR | 3-(1H-indol-2-yl)quinolin-2(1H)-one | Drug Info |
| CAII --- CAI | 1-(3-(2-chlorophenyl)-5-sulfamoyl-1H-indole-2-carboxamido)-2,4,6-trimethylpyridinium perchlorate | Drug Info |
| Ckit --- BRaf | 4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carbamoyl)phenylamino)methyl)-N-cyclopropylpicolinamide | Drug Info |
| CAII --- CAI | ({[2-(4-Sulfamoyl-phenyl)-ethylcarbamoyl]-methyl}-amino)-acetic acid | Drug Info |
| COX2 --- 5LOX | 2,6-Diethyl-4-(2-pyridin-3-yl-vinyl)-phenol | Drug Info |
| CAII --- CAI | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-Heptadecafluoro-nonanoic acid (3-sulfamoyl-phenyl)-amide | Drug Info |
| COX2 --- 5LOX | 2,6-Dimethyl-4-(2-pyridin-2-yl-vinyl)-phenol | Drug Info |
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