Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CAII --- CAI | 4-(2-((1H-pyrrol-2-yl)methyleneamino)ethyl)benzenesulfonamide | Drug Info |
| CAII --- CAI | 2,6-Diisopropyl-1-[(3-methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-2-ylidenecarbamoyl)-methyl]-4-phenyl-pyridinium; perchlorate | Drug Info |
| CAII --- CAI | 4-((6R,7S,8S,10R,11S,12S,14S,15R)-3,12-Di(R)-hydroxy-7-hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid 4-sulfamoyl-benzyl ester | Drug Info |
| CAII --- CAI | 4-{[1-(1H-Imidazol-2-yl)-meth-(Z)-ylidene]-amino}-benzenesulfonamide | Drug Info |
| CAII --- CAI | 2-Propyl-pentanoic acid (2-chloro-4-sulfamoyl-phenyl)-amide | Drug Info |
| CAII --- CAI | 4-(4-(2-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-1-yl)benzenesulfonamide | Drug Info |
| CAII --- CAI | 3-{[(4-tert-butylphenyl)sulfonyl]amino}benzenesulfonamide | Drug Info |
| CAII --- CAIX | 1-(3,4-dichlorophenyl)-3-hydroxyurea | Drug Info |
| CAIX --- CAXII | tert-Butyl 4-methyl-2-oxo-2H-chromen-7-ylcarbamate | Drug Info |
| CALM2 --- Cathepsin B | (1-{1-Benzyl-2-oxo-2-[(pyridin-2-ylmethyl)-carbamoyl]-ethylcarbamoyl}-3-methyl-butyl)-carbamic acid benzyl ester | Drug Info |
| CALM2 --- Cathepsin B | (S)-3-(4-iodophenylsulfonyl)-N-((R,S)-1-oxo-3-phenylpropan-2-yl)thiazolidine-4-carboxamide | Drug Info |
| CALM2 --- Cathepsin B | benzyl 2-(((S)-1-oxo-3-phenylpropan-2-yl)carbamoyl)-3-methylbutanoate | Drug Info |
| Cathepsin K --- Cathepsin B | (S)-1-(5,6-dichloro-1H-benzo[d]imidazol-1-yl)-3,3-dimethylbutan-2-yl (S)-3-oxo-4-(pyridine-2-sulfonamido)butan-2-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | (S)-N-(1-(2-(4-methoxyphenylamino)ethylamino)-4-methyl-1-oxopentan-2-yl)-3-methylbenzamide | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid (1S,3S,5R)-3,5-dimethyl-cyclohexyl ester | Drug Info |
| Cathepsin K --- MEP | N-((S)-3-(7,7-dimethylbicyclo[2.2.1]heptan-1-yl)-1-((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)-1-oxopropan-2-yl)morpholine-4-carboxamide | Drug Info |
| Cathepsin K --- MEP | benzyl (S)-1-oxo-1-((3R,4R)-2-oxo-4-phenoxyazetidin-3-ylamino)-3-phenylpropan-2-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | (S)-N-((S)-1-(5-(furan-2-yl)-1,3,4-oxadiazol-2-yl)-1-oxopentan-2-yl)-4-methyl-2-(2,2,2-trifluoroethylamino)pentanamide | Drug Info |
| Cathepsin K --- MEP | (R)-2-{3'-[2-(4-tert-butyl-piperazin-1-yl)-thiazol-4-yl]-biphenyl-3-yl}-4-methyl-pentanoic acid cyanomethyl-amide | Drug Info |
| Cathepsin K --- MEP | N-((S)-3-cyclohexyl-1-((S)-1-(5-fluoroindolin-1-yl)propan-2-ylamino)-1-oxopropan-2-yl)morpholine-4-carboxamide | Drug Info |
| Cathepsin K --- MEP | 2',3',4'-trifluoro-biphenyl-2-yloxy-acetaldehyde | Drug Info |
| CCKBR --- CCKAR | N-tert-Butyl-2-{(3R,5R)-3-[3-(3-chloro-phenyl)-ureido]-7-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-acetamide | Drug Info |
| CCKBR --- CCKAR | 3-(2-Amino-3-naphthalen-1-yl-propionylamino)-N-({[1-tert-butoxycarbonyl-2-(1H-indol-3-yl)-ethyl]-methyl-carbamoyl}-cyclohexyl-methyl)-succinamic acid | Drug Info |
| CCKBR --- CCKAR | (S)-2-(2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-4-chlorobenzamido)-3-(4-chlorophenyl)-3-methylbutanoic acid | Drug Info |
| CCKBR --- CCKAR | N-tert-Butyl-2-{(3R,5S,7R)-2-oxo-7-phenyl-5-o-tolyl-3-[3-(3-trifluoromethyl-phenyl)-ureido]-azepan-1-yl}-acetamide | Drug Info |
| CCKBR --- CCKAR | N-tert-Butyl-2-((3R,5S)-5-cyclohexylmethyl-8-methyl-2-oxo-3-{3-[3-(1H-tetrazol-5-yl)-phenyl]-ureido}-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl)-acetamide | Drug Info |
| CCKBR --- CCKAR | 2-[(3R,5S,7R)-2-Oxo-7-phenyl-5-o-tolyl-3-(3-m-tolyl-ureido)-azepan-1-yl]-N-o-tolyl-acetamide | Drug Info |
| CCKBR --- CCKAR | 3-{5-tert-Butoxycarbonylamino-2-[2-tert-butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-pentanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid | Drug Info |
| CCKBR --- CCKAR | CCK7 analogue | Drug Info |
| CCKBR --- CCKAR | [2-(4-Benzoyl-piperidin-1-yl)-1-(1H-indol-3-ylmethyl)-1-methyl-2-oxo-ethyl]-carbamic acid adamantan-2-yl ester | Drug Info |
| CCKBR --- CCKAR | 1H-Indole-2-carboxylic acid [5-(2-fluoro-phenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-amide | Drug Info |
| CCKBR --- CCKAR | Tyr-D-Phe-Gly-Trp-Nle-Asp-Phe-NH2 | Drug Info |
| CD135 --- Ckit | (4-(5-amino-1-(pyridin-2-yl)-1H-1,2,4-triazol-3-ylamino)phenyl)(morpholino)methanone | Drug Info |
| CD221 --- JNK1 | 2-(2-(1-(2-(dimethylamino)ethyl)-5-methoxyindolin-6-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-6-fluorobenzamide | Drug Info |
| CDK1 --- CDK2 | 4-((2-oxo-2,3-dihydropyrrolo[3,2-f]quinolin-1-ylidene)methylamino)benzenesulfonamide | Drug Info |
| CDK1 --- CDK2 | 3-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-benzenesulfonamide | Drug Info |
| CDK1 --- GSK3 | Thieno analogue of kenpaullone | Drug Info |
| CDK1 --- GSK3 | 2-((E)-3-oxo-but-1-enyl)-9-trifluoromethyl-5,12-dihydro-7H-benzo[2,3]azepino[4,5-b]indol-6-one | Drug Info |
| CDK1 --- GSK3 | (9-Bromo-6-oxo-6,7-dihydro-12H-benzo[2,3]azepino[4,5-b]indol-5-yl)-acetic acid methyl ester | Drug Info |
| CDK1 --- VEGFR | 3-{4-[6-(3-Chloro-phenylamino)-pyrazin-2-yl]-pyridin-2-ylamino}-propan-1-ol | Drug Info |
| CDK2 --- AKT | (S)-N1-(5-(isoquinolin-6-yl)-1,3,4-thiadiazol-2-yl)-3-(4-(trifluoromethyl)phenyl)propane-1,2-diamine | Drug Info |
| CDK2 --- AuroraA | N,1,4,4-Tetramethyl-8-{[4-(morpholin-4-ylmethyl)phenyl]-amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- CD135 | (16E)-14-Methyl-5,7,14,20,26-pentaazatetracyclo[19.3.1.1-(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene-19-one | Drug Info |
| CDK2 --- CDK1 | (3S,5S)-N-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-yl)-5-methylpiperidine-3-carboxamide | Drug Info |
| CDK2 --- CDK1 | 2-(3-chloro-4-hydroxy-phenyl)-8-(1,1-dioxo-1lambda*6*-isothiazolidin-2-yl)-3-hydroxy-6-methyl-chromen-4-one | Drug Info |
| CDK2 --- CDK1 | SID174007074 | Drug Info |
| CDK2 --- CDK1 | (Z)-4-(1-(5-chloro-2-oxoindolin-3-ylidene)ethylamino)benzenesulfonamide | Drug Info |
| CDK2 --- CDK1 | (3S,4S)-1-(3-(2-aminopyrimidin-4-yl)-4-hydroxyphenyl)pyrrolidine-3,4-diol | Drug Info |
| CDK2 --- CDK1 | 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione | Drug Info |
| CDK2 --- CDK4 | 4-(4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-ylamino)benzoic acid | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.