Multi-target agents
Target Pair | Drug Name | |
---|---|---|
CDK1 --- VEGFR | 5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1H-indol-6-yl)pyrimidin-2-amine | Drug Info |
CDK2 --- AKT | (S)-3-(2-chlorophenyl)-N1-(5-(3-methyl-1H-indazol-5-yl)-1,3,4-thiadiazol-2-yl)propane-1,2-diamine | Drug Info |
CDK2 --- AuroraA | 1-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylic acid | Drug Info |
CDK2 --- AuroraA | 8-[(3-Methoxyphenyl)amino]-1-methyl-4,5-dihydro-1H-pyrazolo-[4,3-h]quinazoline-3-carboxamide | Drug Info |
CDK2 --- CDK1 | 2-oxo-3-[1-(4-sulfamoyl-phenylamino)-meth-(Z)-ylidene]-2,3-dihydro-1H-indole-5-carboxylic acid methyl ester | Drug Info |
CDK2 --- CDK1 | CHEMBL451462 | Drug Info |
CDK2 --- CDK1 | 4-[5-(3-Methoxy-phenyl)-2H-pyrazol-3-ylamino]-benzenesulfonamide | Drug Info |
CDK2 --- CDK1 | 4-[6-Amino-5-(2,6-difluoro-benzoyl)-pyridin-2-ylamino]-benzenesulfonamide | Drug Info |
CDK2 --- CDK1 | 2-[4-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-phenyl]-acetamide | Drug Info |
CDK2 --- CDK1 | 2-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-ethanol | Drug Info |
CDK2 --- CDK1 | (Z)-4-(2-(4-(4-hydroxyphenethyl)-2-oxoindolin-3-ylidene)hydrazinyl)benzenesulfonamide | Drug Info |
CDK2 --- CDK4 | GW781673X | Drug Info |
CDK2 --- CDK4 | (3-Methoxy-5-trifluoromethyl-phenyl)-(4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-yl)-amine | Drug Info |
CDK2 --- CDK4 | N-(5-(2-(cyclohexyloxy)-5-methylpyrimidin-4-yl)thiazol-2-yl)pyridin-2-amine | Drug Info |
CDK2 --- Cmet | 2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-2-methylbenzoyl)piperazin-1-yl)ethanone | Drug Info |
CDK2 --- Cyclin E | N-(3-tert-Butyl-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl)-acetamide | Drug Info |
CDK2 --- Cyclin E | N6-(biphenyl-4-ylmethyl)-N2-(trans-4-(ethylamino)cyclohexyl)-9-isopropyl-9H-purine-2,6-diamine hydrochloride | Drug Info |
CDK2 --- Cyclin E | (2,6-Bis-trifluoromethyl-quinazolin-4-yl)-tert-butyl-amine | Drug Info |
CDK2 --- Cyclin E | N*6*-Biphenyl-4-ylmethyl-9-isopropyl-N*2*,N*2*-bis-(2-methoxy-ethyl)-9H-purine-2,6-diamine | Drug Info |
CDK2 --- Cyclin E | 3-Ethyl-6-(2-hydroxy-benzyl)-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
CDK2 --- Cyclin E | 3-Ethyl-6-(3-methyl-benzyl)-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
CDK2 --- Cyclin E | N-[5-(4-Ethyl-oxazol-2-ylmethylsulfanyl)-thiazol-2-yl]-acetamide | Drug Info |
CDK2 --- GSK3 | N-(6-(furan-2-yl)-1H-indazol-3-yl)cyclopropanecarboxamide | Drug Info |
CAII --- CAI | 6-(Nonafluorobutane-1-sulfonylamino)-benzothiazole-2-sulfonic acid amide | Drug Info |
CDK4 --- Cyclin E | 1-Morpholin-4-yl-3-{4-oxo-3-[5-(piperidine-1-carbonyl)-thiophen-2-yl]-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-urea | Drug Info |
CAII --- CAI | 6-[2-(4-Sulfamoyl-phenyl)-ethoxycarbamoyl]-pyridine-2-carboxylic acid | Drug Info |
Ckit --- BRaf | 4-((5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carbamoyl)thiazol-4-ylamino)methyl)-N-methylpicolinamide | Drug Info |
CAII --- CAI | (3aS,3bR,7aS,8aR)-N-(aminosulfonyl)-2,2,5,5-tetramethyltetrahydro-8aH-[1,3]dioxolo[4,5]furo[3,2-d][1,3]dioxine-8a-carboxamide | Drug Info |
COX2 --- 5LOX | 3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)phenoxymethyl]-1,5-diphenyl-1H-pyrazole | Drug Info |
CAII --- CAI | ([2-(Carboxymethyl-{[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-methyl}-amino)-ethyl]-{[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-methyl}-amino)-acetic acid; compound with Zn complex | Drug Info |
COX2 --- 5LOX | 1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-hexan-1-one | Drug Info |
CAII --- CAI | (S)-2-(4-Chloro-3-sulfamoyl-benzoylamino)-3-methyl-butyric acid | Drug Info |
COX2 --- 5LOX | (7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-thiophen-2-yl-methanone | Drug Info |
CAII --- CAI | [Carboxymethyl-(4-sulfamoyl-benzyloxycarbonylmethyl)-amino]-acetic acid | Drug Info |
CSrc --- CABL | N-(5-(3-chlorobenzylthio)-1,3,4-thiadiazol-2-yl)-4-chlorobenzamide | Drug Info |
CSrc --- CABL | 1-(2-bromo-2-phenylethyl)-N-butyl-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
CAII --- CAI | 6-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2Z)-ylidenecarbamoyl]-pyridine-2-carboxylic acid | Drug Info |
CSrc --- CABL | tert-butyl 3-(4-(6-(2,6-dichlorophenyl)-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-ylamino)phenylamino)-3-oxopropylcarbamate | Drug Info |
CAII --- CAI | [(S)-2-(4-Chloro-3-sulfamoyl-benzoylamino)-3-(3H-imidazol-4-yl)-propionylamino]-acetic acid | Drug Info |
CSrc --- CABL | 1-[2-Chloro-2-(4-fluorophenyl)ethyl]-N-(pyridin-2-ylmethyl)-1Hpyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
CAII --- CAI | 4-amino-N-(3-sulfamoylphenyl)benzenesulfonamide | Drug Info |
CSrc --- CABL | N-(4-(dipropylphosphoryl)phenyl)-2-isopropyl-9-styryl-9H-purin-6-amine | Drug Info |
CAII --- CAI | 2,6-Diethyl-4-phenyl-1-{[4-(3-sulfamoyl-phenylsulfamoyl)-phenylcarbamoyl]-methyl}-pyridinium; perchlorate | Drug Info |
CSrc --- CABL | N-(5-(4-nitrobenzylthio)-1,3,4-thiadiazol-2-yl)-4-chlorobenzamide | Drug Info |
CAII --- CAI | SID24794411 | Drug Info |
CSrc --- Ckit | 3-(2-aminoquinazolin-6-yl)-1-(4-methoxyphenyl)-4-methylpyridin-2(1H)-one | Drug Info |
CAII --- CAI | 4-{1-[4-(aminosulfonyl)phenyl]-1H-1,2,3-triazol-4-yl}benzenesulfonamide | Drug Info |
DHFR --- TYMS | CHEMBL3303081 | Drug Info |
CAII --- CAI | (1R,2R)-4-((8S,9S,12R,14R,17S)-3-(R)-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid (2-sulfamoyl-benzothiazol-6-yl)-amide | Drug Info |
DHFR --- TYMS | N-{4-[(2-amino-6-methyl-4-oxo-3,4-dihydro-5 H-pyrrolo[3,2-d]pyrimidin-5-yl)methyl]benzoyl}-l-glutamic acid | Drug Info |
Pagination
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