Multi-target agents
Target Pair | Drug Name | |
---|---|---|
EGFR3 --- HER2 | 4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)-6-aminopyrimidine-5-carbaldehyde O-2-methoxyethyl oxime | Drug Info |
CAII --- CAI | {{2-[2-(2-{Carboxymethyl-[(4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-ethoxy)-ethoxy]-ethyl}-[(4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-acetic acid; compound with Zn complex | Drug Info |
EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-5-((5-(pyrrolidin-1-ylmethyl)thiazol-2-yl)ethynyl)pyrimidin-4-amine | Drug Info |
CAII --- CAI | 3-Chloro-4-[(7-chloro-2-oxo-2H-chromen-4-ylmethyl)-amino]-benzenesulfonamide | Drug Info |
CAII --- CAI | 4-(((1R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methylsulfonamido)benzenesulfonamide | Drug Info |
CAII --- CAI | [Carboxymethyl-(2-{carboxymethyl-[2-(carboxymethyl-{[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-methyl}-amino)-ethyl]-amino}-ethyl)-amino]-acetic acid | Drug Info |
CAII --- CAI | (sulfamoylamino)methylbenzene | Drug Info |
CAII --- CAI | (S)-2-[(S)-2-(4-Chloro-3-sulfamoyl-benzoylamino)-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionic acid | Drug Info |
CAII --- CAI | N-(2-Amino-acetyl)-4-hydroxymethyl-benzenesulfonamide | Drug Info |
CAII --- CAI | 4-phenylacetamidomethyl-benzenesulfonamide | Drug Info |
CAII --- CAIX | 2-Hydrazinocarbonyl-benzenesulfonamide | Drug Info |
CAII --- CAIX | 1-(2-fluoro-4-{[(4-sulfamoylphenyl)methyl]sulfamoyl}phenyl)-3-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl}thiourea | Drug Info |
CAIX --- CAXII | N1-(naphthalen-1-yl)ethane-1,2-diamine | Drug Info |
CALM2 --- Cathepsin B | 3-(2-Diphenylacetylamino-4-methyl-pentanoylamino)-2-oxo-pentanoic acid (pyridin-2-ylmethyl)-amide | Drug Info |
CALM2 --- Cathepsin B | [(S)-1-((S)-1-Benzyl-2-oxo-2-phenethylcarbamoyl-ethylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester | Drug Info |
CALM2 --- Cathepsin B | CHEMBL304784 | Drug Info |
Cathepsin K --- Cathepsin B | (R)-N-(1-cyanocyclopropyl)-3-(methylsulfinyl)-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)propanamide | Drug Info |
Cathepsin K --- MEP | 9-Cyclopentyl-6-[2-(3-imidazol-1-yl-propoxy)-phenylamino]-9H-purine-2-carbonitrile | Drug Info |
Cathepsin K --- MEP | N-((S)-1-((R)-2-(benzyloxy)-1-cyanoethylamino)-4-methyl-1-oxopentan-2-yl)-1-methyl-1H-indole-2-carboxamide | Drug Info |
Cathepsin K --- MEP | [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid (S)-indan-1-yl ester | Drug Info |
Cathepsin K --- MEP | N-{(S)-1-[2-(4-Isobutoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-4-methoxy-benzamide | Drug Info |
Cathepsin K --- MEP | (S)-N-(3-cyclohexyl-1-oxo-1-(2-(4-(trifluoromethoxy)phenylamino)ethylamino)propan-2-yl)furan-2-carboxamide | Drug Info |
Cathepsin K --- MEP | benzyl (S)-1-((R)-2-tert-butoxy-1-cyanoethylamino)-4-methyl-1-oxopentan-2-ylcarbamate | Drug Info |
Cathepsin K --- MEP | [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl ester | Drug Info |
Cathepsin K --- MEP | [(S)-1-((S)-1-Benzyl-2-phenylamino-ethylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester | Drug Info |
CCKBR --- CCKAR | (R)Quinoline-3-carboxylic acid [1-dipentylcarbamoyl-2-(5-hydroxy-1H-indol-3-yl)-ethyl]-amide | Drug Info |
CCKBR --- CCKAR | Quinoline-3-carboxylic acid [1-dipentylcarbamoyl-2-(5-fluoro-1H-indol-3-yl)-ethyl]-amide | Drug Info |
CCKBR --- CCKAR | H-Tyr-D-Phe-Glu-Trp-N-MeNle-Asp-Phe-NH2 | Drug Info |
CCKBR --- CCKAR | 3-{5-Amino-2-[2-tert-butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-pentanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid | Drug Info |
CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(2,3-dichloro-phenyl)-ureido]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid | Drug Info |
CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(4-chloro-phenyl)-propionylamino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid; hydrate | Drug Info |
CCKBR --- CCKAR | (S)-3-(3-bromo-4-fluorophenyl)-2-(4-chloro-2-(quinoxaline-5-sulfonamido)benzamido)propanoic acid | Drug Info |
CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(2,4-dichloro-phenyl)-ureido]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid | Drug Info |
CCKBR --- CCKAR | 3-{3-[(3R,5R)-1-(tert-Butylcarbamoyl-methyl)-8-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl]-ureido}-benzoic acid methyl ester | Drug Info |
CCKBR --- CCKAR | 3-{6-[(6-Acetoxy-naphthalene-2-carbonyl)-amino]-2-[2-tert-butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-N-methyl-succinamic acid; hydrate | Drug Info |
CD135 --- Ckit | 4-(5-amino-1-(pyridin-2-yl)-1H-1,2,4-triazol-3-ylamino)-N-(2-morpholinoethyl)benzamide | Drug Info |
CD221 --- JNK1 | 2-(2-(1-acetyl-6-methoxy-1,2,3,4-tetrahydroquinolin-7-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-6-fluorobenzamide | Drug Info |
CDK1 --- CDK2 | 2-oxo-3-[(4-sulfamoyl-phenyl)-hydrazono]-2,3-dihydro-1H-indole-5-carboxylic acid dimethylamide | Drug Info |
CDK1 --- CDK2 | (6-Cyclohexylmethoxy-9H-purin-2-yl)-(4-methanesulfonyl-phenyl)-amine | Drug Info |
CDK1 --- CDK4 | 2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-chromen-4-one | Drug Info |
CDK1 --- GSK3 | 2-Iodo-9-trifluoromethyl-5,12-dihydro-7H-benzo[2,3]azepino[4,5-b]indol-6-one | Drug Info |
CDK1 --- GSK3 | 7-Benzyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazine | Drug Info |
CDK1 --- VEGFR | 5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(2,4-dimethylthiazol-5-yl)pyrimidin-2-amine | Drug Info |
CDK2 --- AKT | (S)-N1-(5-(3-phenyl-1H-indazol-5-yl)-1,3,4-thiadiazol-2-yl)-3-(3-(trifluoromethyl)phenyl)propane-1,2-diamine | Drug Info |
CDK2 --- AuroraA | 8-[(2-Aminophenyl)amino]-1-methyl-4,5-dihydro-1H-pyrazolo-[4,3-h]quinazoline-3-carboxamide | Drug Info |
CDK2 --- AuroraA | N,1,4,4-Tetramethyl-8-[(4-morpholin-4-ylphenyl)amino]-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
CDK2 --- CDK1 | 3-(6-Amino-9-isopropyl-9H-purin-2-ylamino)-propan-1-ol | Drug Info |
CDK2 --- CDK1 | N-(2-Hydroxy-ethyl)-C-{4-[(7-oxo-6,7-dihydro-thiazolo[5,4-e]indol-8-ylidenemethyl)-amino]-phenyl}-methanesulfonamide | Drug Info |
CDK2 --- CDK1 | (Z)-4-((6-(hydroxymethyl)-2-oxoindolin-3-ylidene)methylamino)benzenesulfonamide | Drug Info |
CDK2 --- CDK1 | GW290597X | Drug Info |
Pagination
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