Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CAII --- CAI | 2,6-Diisopropyl-4-phenyl-1-(2-sulfamoyl-benzothiazol-6-yloxycarbonylmethyl)-pyridinium; perchlorate | Drug Info |
| EGFR3 --- HER2 | 4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)-6-aminopyrimidine-5-carbaldehyde O-benzyl oxime | Drug Info |
| CAII --- CAI | 4,5-Dichloro-6-[(7-chloro-2-oxo-2H-chromen-4-ylmethyl)-amino]-benzene-1,3-disulfonic acid diamide | Drug Info |
| EGFR3 --- HER2 | {4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl}-carbamic acid cis-4-amino-4-methylcyclohexyl ester | Drug Info |
| CAII --- CAI | Sulfamic acid propyl ester | Drug Info |
| EGFR3 --- HER2 | 2-(4-Hydroxy-3-methoxy-5-phenylsulfanylmethyl-benzylidene)-malononitrile | Drug Info |
| CAII --- CAI | [(S)-4-Methyl-2-(4-sulfamoyl-benzoylamino)-pentanoylamino]-acetic acid | Drug Info |
| EGFR3 --- HER2 | 4-(3-bromo-2-methylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile | Drug Info |
| CAII --- CAI | 4-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-ylidenesulfamoyl]-benzoic acid 2-dimethylamino-1-methyl-ethyl ester | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| CAII --- CAI | 4-(2-(3-nitrobenzylideneamino)ethyl)benzenesulfonamide | Drug Info |
| CAII --- CAI | {(2-{2-[2-(Bis-carboxymethyl-amino)-ethoxy]-ethoxy}-ethyl)-[(2-bromo-4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-acetic acid; compound with Zn complex | Drug Info |
| CAII --- CAI | 4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesulfonic acid | Drug Info |
| CAII --- CAI | N-(2-chloro-4-sulfamoylphenyl)-2-phenylacetamide | Drug Info |
| CAII --- CAI | 2-[(1E)-{[2-(4-sulfamoylphenyl)ethyl]imino}methyl]phenyl N-[(4-chlorobenzene)sulfonyl]carbamate | Drug Info |
| CAII --- CAI | (S)-3-Methyl-2-[3-(4-sulfamoyl-phenyl)-thioureido]-butyric acid | Drug Info |
| CAII --- CAI | 4-Chloro-N-(5-mercapto-[1,3,4]thiadiazol-2-yl)-3-sulfamoyl-benzamide | Drug Info |
| CAII --- CAIX | 4-Amino-3-bromo-5-iodo-benzenesulfonamide | Drug Info |
| CAII --- CAXII | Resorcinol | Drug Info |
| CAIX --- CAXII | SID29218043 | Drug Info |
| CALM2 --- Cathepsin B | (S)-3-(4-chlorophenylsulfonyl)-N-((R,S)-1-oxo-3-phenylpropan-2-yl)thiazolidine-4-carboxamide | Drug Info |
| CALM2 --- Cathepsin B | {3-Methyl-1-[1-(3-morpholin-4-yl-propylaminooxalyl)-butylcarbamoyl]-butyl}-carbamic acid benzyl ester | Drug Info |
| CALM2 --- Cathepsin B | 5-Amino-N-cyclopropyl-3-(4-isopropylphenyl)-4-oxo-3,4-dihydrothieno[3,4-d]pyridazine-1-carboxamide | Drug Info |
| Cathepsin K --- Cathepsin B | [(S)-2-Pyridin-3-yl-1-((5S,6R)-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-ethyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | 2-(cyclohexylmethyl)-N-(4-(methylsulfonyl)-1-(4-(trifluoromethoxy)phenylamino)butan-2-yl)-4-morpholino-4-oxobutanamide | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-cyclohexylamino-pyrimidine-5-carboxylic acid [2-(4-pyrrolin-1-ylphenyl)-ethyl]-amide | Drug Info |
| Cathepsin K --- MEP | 1H-Indole-2-carboxylic acid {(S)-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-amide | Drug Info |
| Cathepsin K --- MEP | (S)-4-morpholino-4-oxo-2-phenyl-N-((S)-4-phenyl-1-(4-(trifluoromethoxy)phenylamino)butan-2-yl)butanamide | Drug Info |
| Cathepsin K --- MEP | (R)-4-methyl-2-[3'-(2-piperazin-1-ylmethyl-thiazol-4-yl)-biphenyl-3-yl]-pentanoic acid cyanomethyl-amide | Drug Info |
| Cathepsin K --- MEP | N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]phenylcarbamoyl}-leucyl-glycine-nitrile | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid bicyclo[2.2.1]hept-2-yl ester | Drug Info |
| Cathepsin K --- MEP | (S)-N-(3-(3-chlorophenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)cycloheptanecarboxamide | Drug Info |
| CCKBR --- CCKAR | N-tert-Butyl-2-{(3S,5R)-3-[3-(3-chloro-phenyl)-ureido]-5-cyclohexyl-2-oxo-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-acetamide | Drug Info |
| CCKBR --- CCKAR | N-(2-Oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-4-propyl-benzamide | Drug Info |
| CCKBR --- CCKAR | N-tert-Butyl-2-{(3R,5R)-8-methyl-2-oxo-5-phenyl-3-[3-(3-trifluoromethanesulfonylaminocarbonyl-phenyl)-ureido]-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-acetamide | Drug Info |
| CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[(5-hydroxy-quinoline-3-carbonyl)-amino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid; hydrate | Drug Info |
| CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(4-chloro-phenyl)-acryloylamino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-N-methyl-succinamic acid; hydrate | Drug Info |
| CCKBR --- CCKAR | 2-(4-Chloro-phenyl)-N-[5-(2-fluoro-phenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-acetamide: 0.4H2O | Drug Info |
| CCKBR --- CCKAR | CCK7 analogue | Drug Info |
| CCKBR --- CCKAR | (R)-3-(1H-Indol-3-yl)-N,N-dipentyl-2-(3-p-tolyl-ureido)-propionamide | Drug Info |
| CCKBR --- CCKAR | N-tert-Butyl-2-[(3R,5R)-2-oxo-5-phenyl-3-(3-o-tolyl-ureido)-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl]-acetamide | Drug Info |
| CCKBR --- CCKAR | 3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-(3-o-tolyl-ureido)-hexanoylamino]-N-(1-carbamoyl-2-phenyl-ethyl)-N-methyl-succinamic acid | Drug Info |
| CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[(6-sulfo-naphthalene-2-carbonyl)-amino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid.NH4OH; hydrate | Drug Info |
| CD221 --- JNK1 | 2-(2-(5-(3-(dimethylamino)propyl)-2-methoxyphenylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-6-fluorobenzamide | Drug Info |
| CDK1 --- AuroraA | N-(4-(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylamino)phenyl)-N-(2-hydroxyethyl)methanesulfonamide | Drug Info |
| CDK1 --- CDK2 | 2-oxo-3-[(4-sulfamoyl-phenyl)-hydrazono]-2,3-dihydro-1H-indole-5-carboxylic acid amide | Drug Info |
| CDK1 --- CDK4 | (5-Piperazin-1-yl-pyridin-2-yl)-[4-(3-trifluoromethyl-1H-pyrazol-4-yl)-pyrimidin-2-yl]-amine | Drug Info |
| CDK1 --- GSK3 | (E)-3-(6-Oxo-9-trifluoromethyl-5,6,7,12-tetrahydro-benzo[2,3]azepino[4,5-b]indol-2-yl)-acrylic acid methyl ester | Drug Info |
| CDK1 --- GSK3 | 7-Butyl-6-(4-chloro-phenyl)-5H-pyrrolo[2,3-b]pyrazine | Drug Info |
| CDK1 --- VEGFR | N-(3-chlorophenyl)-6-(5-{[3-(piperidin-1-yl)propyl]amino}pyridin-3-yl)pyrazin-2-amine | Drug Info |
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