Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| PR --- mRNA of AR | SID3714042 | Drug Info |
| Erbeta --- ER | 3-(3-fluoro-4-hydroxyphenyl)benzo[d]isoxazol-6-ol | Drug Info |
| JNK3 --- MAPK | 2-Hydroxy-N-[2-(6-naphthalen-1-yl-5-pyridin-4-yl-pyridazin-3-ylamino)-1-((S)-phenylmethyl)-ethyl]-acetamide | Drug Info |
| PR --- mRNA of AR | (-)-(S)-3-tert-butyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate | Drug Info |
| Erbeta --- ER | 2-(3-Hydroxy-phenyl)-1-[4-(4-methyl-piperazin-1-yl)-phenyl]-1,2,3,4-tetrahydro-isoquinolin-6-ol | Drug Info |
| MEP --- Cathepsin B | 1-((3-fluorophenyl)(p-tolyl)methylene)thiosemicarbazide | Drug Info |
| PR --- mRNA of AR | (+)-4-(1-benzyl-4,4-dimethyl-2-oxopyrrolidin-3-yloxy)-2-(trifluoromethyl)benzonitrile | Drug Info |
| Erbeta --- ER | 5-ethyl-7-hydroxy-3-(4-hydroxyphenyl)-3H-quinazoline-4-thione | Drug Info |
| MEP --- Cathepsin B | SID90419368 | Drug Info |
| PR --- mRNA of AR | 5-Bromo-2-(2,2-dimethyl-5-methylene-cyclopentylmethyl)-4-methoxy-phenol | Drug Info |
| Erbeta --- ER | (S)-2,3-Bis(4-hydroxyphenyl)propanenitrile | Drug Info |
| MEP --- Cathepsin B | (S)-N-((S)-1-cyano-2-phenylethyl)-3-cyclopropyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)propanamide | Drug Info |
| PR --- mRNA of AR | 1,8,8,9-Tetramethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one | Drug Info |
| Erbeta --- ER | 3-(6-hydroxynaphthalen-2-yl)benzo[d]isoxazol-5-ol | Drug Info |
| MEP --- Cathepsin B | (S)-3-Methyl-2-(naphthalene-2-sulfonylamino)-pentanoic acid [(R)-1-formyl-2-(1H-indol-3-yl)-ethyl]-amide | Drug Info |
| PR --- mRNA of AR | 9-(3-Iodo-phenylamino)-6-methyl-4-oxo-6,7-dihydro-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid | Drug Info |
| Erbeta --- ER | [2-(4-Hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanone; hydrochloride | Drug Info |
| Met --- VEGFR | N-(3-fluoro-4-(2-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-2-oxo-3-phenylimidazolidine-1-carboxamide | Drug Info |
| PR --- mRNA of AR | {2-[9-Fluoro-2,2,4-trimethyl-1,2-dihydro-6-oxa-1-aza-chrysen-(5Z)-ylidenemethyl]-phenyl}-dimethyl-amine | Drug Info |
| Erbeta --- ER | [6-Hydroxy-2-(4-hydroxy-phenyl)-3,4-dihydro-2H-quinolin-1-yl]-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanone | Drug Info |
| Met --- VEGFR | 4-(4-(7-(2-fluoro-4-(2-oxo-3-phenylimidazolidine-1-carboxamido)phenoxy)thieno[3,2-b]pyridin-2-yl)benzyl)-N-methylpiperazine-1-carboxamide | Drug Info |
| PR --- mRNA of AR | 15-methyl-N-(1,3,4-thiadiazol-2-yl)tetracyclo[6.6.2.0^{2,7}.0^{9,14}]hexadeca-2,4,6,9(14),10,12-hexaene-15-carboxamide | Drug Info |
| Erbeta --- ER | (4-{4-[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophene-3-carbonyl]-phenyl}-piperazin-1-yl)-(4-nitro-phenyl)-methanone | Drug Info |
| Met --- VEGFR | N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-3-phenyl-2-thioxoimidazolidine-1-carboxamide | Drug Info |
| Renin --- Cathepsin D | (S)-2-amino-4-(3-(cyclopropylethynyl)phenyl)-4-(4-(difluoromethoxy)-3-methylphenyl)-1-methyl-1H-imidazol-5(4H)-one | Drug Info |
| Erbeta --- ER | 1-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-2-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-isoquinolin-6-ol | Drug Info |
| MMP1 --- MMP3 | (R)-2-((S)-4-(4-hydroxyphenyl)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pentan-2-ylamino)-1-oxobutan-2-ylamino)propanoic acid | Drug Info |
| S5AR --- SRD5A2 | N-Phenyl-N-((4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinolin-7-yl)-isobutyramide | Drug Info |
| Erbeta --- ER | [4-(2-Piperidin-1-yl-ethoxy)-phenyl]-[5,6,7-trimethoxy-2-(4-methoxy-phenyl)-benzo[b]thiophen-3-yl]-methanone; hydrochloride | Drug Info |
| MMP1 --- MMP3 | (S)-N-(3,4-Dimethoxy-benzyl)-3-phenyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide | Drug Info |
| S5AR --- SRD5A2 | (4aR,6aS,7S)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (2-chloro-6-trifluoromethyl-phenyl)-amide | Drug Info |
| Erbeta --- ER | 2-hydroxy-4,7-dimethoxyphenanthrene | Drug Info |
| MMP1 --- MMP3 | (S)-2-[(R)-2-((R)-1-Hydroxy-1-hydroxycarbamoyl-ethyl)-5-phenyl-pentanoylamino]-3-phenyl-propionic acid | Drug Info |
| S5AR --- SRD5A2 | (4aR,6aS)-7-(3,4-Dihydro-2H-quinoline-1-carbonyl)-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-indeno[5,4-f]quinolin-2-one | Drug Info |
| Erbeta --- ER | (2S,3R)-2-{4-[2-((R)-3-Fluoro-pyrrolidin-1-yl)-ethoxy]-phenyl}-3-(4-hydroxy-phenyl)-2,3-dihydro-benzo[1,4]oxathiin-6-ol | Drug Info |
| MMP1 --- MMP9 | 1H-Benzotriazole-5-carboxylic acid [(R)-1-((S)-1-carbamoyl-2-pyridin-3-yl-ethylcarbamoyl)-2-mercapto-ethyl]-amide | Drug Info |
| S5AR --- SRD5A2 | (4aR,6aR)-7-(1,5-Dimethyl-hexyl)-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-indeno[5,4-f]quinolin-2-one | Drug Info |
| Erbeta --- ER | 4-bromo-2-(3-fluoro-4-hydroxyphenyl)-7-vinylbenzo[d]oxazol-5-ol | Drug Info |
| MMP13 --- MMP1 | 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(propane-1-sulfonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide | Drug Info |
| S5AR --- SRD5A2 | 7-chloro-4a-methyl-3,4,4a,9-tetrahydrophenanthren-2-ylphosphonous acid | Drug Info |
| Erbeta --- ER | 3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid | Drug Info |
| MMP13 --- MMP1 | 1-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-cyclohexanecarboxylic acid hydroxyamide | Drug Info |
| S5AR --- SRD5A2 | (8S,9S,10R,13S,14S,17S)-17-(diisopropylcarbamoyl)-10,13-dimethyl-8,9,10,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3-carboxylic acid | Drug Info |
| Erbeta --- ER | 2-Benzyl-4-(4-hydroxy-phenyl)-1,2,3,4-tetrahydro-isoquinolin-7-ol | Drug Info |
| MMP13 --- MMP1 | 3-Hydroxy-4-(4-p-tolyloxy-benzenesulfonyl)-tetrahydro-pyran-3-carboxylic acid hydroxyamide | Drug Info |
| S5AR --- SRD5A2 | 3-(17-Diisopropylcarbamoyl-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl)-propionic acid | Drug Info |
| Erbeta --- ER | [2-(4-{1-[4-(2-Diisopropylamino-ethoxy)-phenyl]-3-methyl-but-1-enyl}-phenoxy)-ethyl]-diisopropyl-amine | Drug Info |
| MMP13 --- MMP1 | 4-(2-Amino-acetyl)-1-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide | Drug Info |
| S5AR --- SRD5A2 | 4-Methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]quinoline-8-carboxylic acid p-tolyl ester | Drug Info |
| Erbeta --- ER | (2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-7-ol | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.