Target Pair Drug Name
Ftase --- FPTase (R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propylamino)-3,3-dimethyl-butyryl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-4-methanesulfonyl-butyric acid Drug Info
HER2 --- MMP-2 (2S,3S)-N-hydroxy-5-(N-methylisobutyramido)-2-(4-phenyl-1,2,3,6-tetrahydropyridine-1-carbonyl)piperidine-3-carboxamide Drug Info
Ftase --- FPTase (+)4-(2-{4-[1-butyl-4-chloro-(12R)-3,6,7,12-tetrahydropyrido[2',3':4,5]cyclohepta[e]indol-12-yl]hexahydro-1-pyridinyl}-2-oxoethyl)-1-pyridiniumolate Drug Info
Renin --- Cathepsin D (R)-2-amino-4-(4-(difluoromethoxy)phenyl)-1-methyl-4-(3-(pent-1-ynyl)phenyl)-1H-imidazol-5(4H)-one Drug Info
Ftase --- FPTase [(S)-4-((S)-2-Amino-2-mercapto-ethyl)-3-butyl-piperazin-1-yl]-naphthalen-1-yl-methanone Drug Info
Renin --- Cathepsin D (R)-2-amino-4-(4-(difluoromethoxy)phenyl)-4-(3-(4-methoxybut-1-ynyl)phenyl)-1-methyl-1H-imidazol-5(4H)-one Drug Info
Ftase --- FPTase 1-(((2R,3R)-3-(2,4-dichlorobenzyloxy)-5-fluoro-2,3-dihydrobenzo[b]thiophen-2-yl)methyl)-1H-imidazole Drug Info
EGFR3 --- HER2 N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(5-((2-(methylsulfonyl)ethylamino)methyl)furan-3-yl)thieno[3,2-d]pyrimidin-4-amine Drug Info
Renin --- Cathepsin D (S)-2-amino-4-(3-(cyclopropylethynyl)phenyl)-4-(4-(difluoromethoxy)-3-methylphenyl)-1-methyl-1H-imidazol-5(4H)-one Drug Info
Ftase --- FPTase 1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidine-1-sulfonylmethyl]-7,7-dimethyl-bicyclo[2.2.1]heptan-2-ol Drug Info
EGFR3 --- HER2 N-(4-(3-chloro-4-fluorophenylamino)-3-cyano-7-(trifluoromethoxy)quinolin-6-yl)-4-(dimethylamino)but-2-enamide Drug Info
Renin --- Cathepsin D 2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-pent-4-enoic acid ((1S,2R,3S)-1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexyl)-amide Drug Info
Ftase --- FPTase N-(4-bromophenethyl)-N-((4-(4-cyanobenzyl)-4H-1,2,4-triazol-3-yl)methyl)benzo[d][1,3]dioxole-5-carboxamide Drug Info
EGFR3 --- HER2 (E)-2-Cyano-3-[4-hydroxy-3-methoxy-5-(naphthalen-1-ylsulfanylmethyl)-phenyl]-acrylamide Drug Info
Renin --- Cathepsin D 2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-pent-4-enoic acid [1-cyclohexylmethyl-3,3-difluoro-3-(2-morpholin-4-yl-ethylcarbamoyl)-2-oxo-propyl]-amide Drug Info
Ftase --- FPTase (S)-2-((S)-2-{[(S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methyl-pentyl]-methyl-amino}-3-methyl-pentanoylamino)-4-methylsulfanyl-butyric acid Drug Info
EGFR3 --- HER2 2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3-yloxy)ethanol Drug Info
Renin --- Cathepsin D (R)-2-amino-4-(4-(difluoromethoxy)phenyl)-4-(4-fluoro-3-(3-fluoropropoxy)phenyl)-1-methyl-1H-imidazol-5(4H)-one Drug Info
Ftase --- FPTase [1-(3H-Imidazol-4-ylmethyl)-4-naphthalen-1-yl-1H-pyrrol-3-yl]-phenyl-methanone Drug Info
EGFR3 --- HER2 N-[4-(4-Benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-3-(1H-imidazol-4-yl)-acrylamide Drug Info
mTOR --- AKT N-(6-(3-(4-Methoxyphenylsulfonamido)phenyl)benzo[d]thiazol-2-yl)acetamide Drug Info
Ftase --- FPTase 4-({[4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyano-piperidine-1-carboximidoyl]-amino}-methyl)-piperidine-1-carboxylic acid amide Drug Info
EGFR3 --- HER2 1-(5-Bromo-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylurea Drug Info
mTOR --- AKT N-(6-(6-Chloro-5-(3-chlorophenylsulfonamido)pyridin-3-yl)benzo[d]thiazol-2-yl)acetamide Drug Info
Ftase --- FPTase 1-[4-(8-Chloro-3-ethylamino-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-pyridin-4-yl-ethanone Drug Info
EGFR3 --- HER2 SID506629 Drug Info
mTOR --- AKT (2R,3R)-3-[6-(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]-pyrimidine-5-carbonyl)pyrazin-2-ylamino]-2-(4-fluorophenyl)-pyrrolidine-1-carbaldehyde Drug Info
Ftase --- FPTase 3-(3-(1H-imidazol-1-yl)propyl)-1-(3-bromobenzyl)-5-methyl-5-(naphthalen-1-yl)imidazolidine-2,4-dione Drug Info
EGFR3 --- HER2 4-(4-bromo-3-methylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile Drug Info
mTOR --- AKT N-(5-(6-Chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)-1H-benzo[d]imidazol-2-yl)acetamide Drug Info
Ftase --- FPTase Biphenyl-2-yl-[1-(3H-imidazol-4-ylmethyl)-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-methanone Drug Info
EGFR3 --- HER2 5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-methoxyphenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine Drug Info
mTOR --- AKT N-(6-(2-(N-Ethyl-4-methoxyphenylsulfonamido)pyrimidin-4-yl)benzo[d]thiazol-2-yl)acetamide Drug Info
Ftase --- FPTase 4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1,2-dicarboxylic acid 1-cyclohexylamide 2-[(3-imidazol-1-yl-propyl)-amide] 1-cyclohexylamide 2-{[2-(1H-imidazol-4-yl)-ethyl]-amide} Drug Info
EGFR3 --- HER2 4-Dimethylamino-but-2-enoic acid [4-(1-benzenesulfonyl-1H-indol-5-ylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide Drug Info
mTOR --- PI3K delta 1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)urea Drug Info
Ftase --- FPTase (S)-2-[5-((R)-2-Amino-3-mercapto-propionylamino)-2-(4-methoxy-benzyl)-pentanoylamino]-4-methylsulfanyl-butyric acid Drug Info
EGFR3 --- HER2 N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(5-((2-(methylsulfonyl)ethylamino)methyl)furan-2-yl)thieno[2,3-d]pyrimidin-4-amine Drug Info
mTOR --- PI3K gamma 5-(9-(1-(4-methylbenzyl)piperidin-4-yl)-6-morpholino-9H-purin-2-yl)pyridin-3-ol Drug Info
Ftase --- FPTase 4-{2-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidine-1-carbothioic acid methylamide Drug Info
EGFR3 --- HER2 1-(3,5-Dibromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylthiourea Drug Info
mTOR --- PI3K gamma 4,6-dihydroxy-2-((5-methoxy-2-phenyl-1H-indol-3-yl)methylene)benzofuran-3(2H)-one Drug Info
Ftase --- FPTase 4-(5-{[1-(2-Hydroxy-pyridine-3-carbonyl)-pyrrolidin-3-ylamino]-methyl}-imidazol-1-ylmethyl)-benzonitrile Drug Info
EGFR3 --- HER2 1-(5-Chloro-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea Drug Info
mTOR --- PI3K gamma 1-(4-(2-(3-(hydroxymethyl)phenyl)-6-morpholino-9H-purin-9-yl)piperidin-1-yl)ethanone Drug Info
Ftase --- FPTase 6-(3-Chloro-phenyl)-8-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]-1,2-dihydro-pyrrolo[3,2,1-ij]quinolin-4-one Drug Info
EGFR3 --- HER2 4-Dimethylamino-but-2-enoic acid [4-(4-benzylamino-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide Drug Info
mTOR --- PI3K gamma (3-(6-morpholino-9-(1-(4-(pyridin-4-yl)benzyl)piperidin-4-yl)-9H-purin-2-yl)phenyl)methanol Drug Info
Ftase --- FPTase 2-(1-Acetyl-piperidin-4-yl)-1-[4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-ethanone Drug Info
EGFR3 --- HER2 Pentanedioic acid 3-methoxy-phenyl ester 4-((E)-2-nitro-vinyl)-phenyl ester Drug Info

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