Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| PPAR gamma --- PPAR delta | methyl 2-(2-methyl-4-(3-(2-propyl-4-(trifluoromethyl)phenoxy)propoxy)phenoxy)acetate | Drug Info |
| HDAC1 --- HDAC2 | 7-Phenoxy-heptanoic acid hydroxyamide | Drug Info |
| Erbeta --- ER | 2,2,2-Trichloro-1-(6-hydroxy-3,4-dihydroisoquinolin-2(1H)-yl)ethanone | Drug Info |
| PPAR gamma --- PPAR delta | 2-(3-(5-methoxy-4-methyl-1H-indol-1-ylsulfonyl)benzamido)-5-methylbenzoic acid | Drug Info |
| HDAC1 --- HDAC2 | 4-(3-(4-(4-Chlorobenzyloxy)-3-methoxyphenyl)propanamido)-N-hydroxybenzamide | Drug Info |
| Erbeta --- ER | 4-{3-Ethyl-5-phenyl-4-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-furan-2-yl}-phenol | Drug Info |
| PPAR gamma --- PPAR delta | 2-(1-{3-[4-(4-Methoxy-benzoyl)-2-propyl-phenoxy]-propyl}-1H-indol-5-yloxy)-2-methyl-propionic acid | Drug Info |
| HDAC1 --- HDAC2 | 1H-Indole-6-carboxylic acid (5-hydroxycarbamoyl-pentyl)-amide | Drug Info |
| Erbeta --- ER | [6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(2-piperidin-1-yl-ethylamino)-phenyl]-methanone | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-(N-butyl-N-(4'-methoxy-2-methylbiphenyl-3-yl)sulfamoyl)-2,3-dimethylphenoxy)propanoic acid | Drug Info |
| HDAC1 --- HDAC4 | N-hydroxy-3-(4-(phenylsulfonamido)phenyl)acrylamide | Drug Info |
| Erbeta --- ER | 6-(3-hydroxyphenyl)naphthalen-1-ol | Drug Info |
| PPAR gamma --- PPAR delta | 3-{4-[2-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-ethoxy]-phenyl}-propionic acid | Drug Info |
| HER2 --- CD221 | 2-cyclohexyl-N-(3-(5-(2-(4-morpholinophenylamino)pyrimidin-4-yl)imidazo[2,1-b]thiazol-6-yl)phenyl)acetamide | Drug Info |
| Erbeta --- ER | (13R,14aS)-13-Methoxy-cryptopleurine | Drug Info |
| PPAR gamma --- PPAR delta | rac-2-(4-Methoxy-3-((4-(trifluoromethoxy)benzamido)methyl)benzyl)butanoic acid | Drug Info |
| IKKbeta --- JAK2 | (4-(4-(5-(4-hydroxybutyl)thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone | Drug Info |
| Erbeta --- ER | [4-(4-Cyclopentyl-piperazin-1-yl)-phenyl]-[6-hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-methanone | Drug Info |
| PPAR gamma --- PPAR delta | CHEMBL25710 | Drug Info |
| JNK1 --- JNK3 | 3-[6-(2-Chloro-phenylamino)-1H-indazol-3-yl]-N-(2-dimethylamino-ethyl)-benzamide | Drug Info |
| Erbeta --- ER | (R)-N-(4-(4-hydroxyphenyl)butan-2-yl)-2-(2-phenyl-6-(4-(piperidin-1-yl)butoxy)-1H-indol-3-yl)acetamide | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-((3-(4-isopropylphenyl)-1-methyl-1H-pyrazole-5-carboxamido)methyl)-2-methylphenoxy)-2-methylpropanoic acid | Drug Info |
| JNK1 --- JNK3 | methyl 5-(2-(isoquinolin-5-yl)acetamido)thiazole-4-carboxylate | Drug Info |
| Erbeta --- ER | Methanesulfonic acid 4-((11S,13S,17S)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-11-yl)-butyl ester | Drug Info |
| PPAR gamma --- PPAR delta | (E)-3-{2-Methyl-4-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-phenyl}-acrylic acid | Drug Info |
| JNK1 --- JNK3 | methyl 2-(2-(isoquinolin-5-yl)acetamido)-4-methylthiophene-3-carboxylate | Drug Info |
| Erbeta --- ER | 2-(2-phenyl-1H-indol-3-yl)-N-(4-phenylbutan-2-yl)acetamide | Drug Info |
| PPAR gamma --- PPAR delta | 5-chloro-2-(3-(5-hydroxy-3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)benzamido)benzoic acid | Drug Info |
| JNK1 --- JNK3 | methyl 3-(2-phenylacetamido)thiophene-2-carboxylate | Drug Info |
| Erbeta --- ER | 9a-benzyl-6-methyl-8,9,9a,10-tetrahydroindeno[2,1-e]indazol-7(3H)-one | Drug Info |
| PPAR gamma --- PPAR delta | 2-methyl-2-(2-methyl-4-(3-((2-phenoxy-4-(trifluoromethyl)benzamido)methyl)phenoxy)phenoxy)propanoic acid | Drug Info |
| JNK1 --- JNK3 | 2-(2-(3,4-dichlorophenoxy)-5-(trifluoromethyl)pyridin-4-ylamino)benzamide | Drug Info |
| Erbeta --- ER | 2-(3-Chloro-phenyl)-1-methyl-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-1,2,3,4-tetrahydro-isoquinolin-6-ol | Drug Info |
| PPAR gamma --- PPAR delta | 2-(2,3-dimethyl-4-(2-(pyridin-3-ylmethoxy)-4-((4-(trifluoromethyl)phenoxy)methyl)phenylthio)phenoxy)acetic acid | Drug Info |
| JNK1 --- JNK3 | N-(4-(methylsulfonyl)benzyl)-4-amino-6-ethoxy-5-vinylpicolinamide | Drug Info |
| Erbeta --- ER | (S)-9a-butyl-6-(trifluoromethyl)-8,9,9a,10-tetrahydroindeno[2,1-e]indazol-7(3H)-one | Drug Info |
| JNK1 --- JNK3 | N-(4-bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(5-oxo-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-4(5H)-yl)acetamide | Drug Info |
| Erbeta --- ER | 3-phenyl-4-[4-(2-tetrahydro-1H-1-pyrrolylethylsulfanyl)phenyl]-(3S,4R)-3,4-dihydro-2H-7-chromenol; Compound with Hydrochloric acid | Drug Info |
| JNK1 --- JNK3 | 4-(6-aminonaphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one | Drug Info |
| PPAR gamma --- PPAR delta | 2-{4-[2-(5,6,7,8-Tetrahydro-naphthalen-2-yloxy)-ethoxy]-benzyl}-malonic acid monomethyl ester | Drug Info |
| Erbeta --- ER | 4-(3-(4-hydroxyphenyl)-1H-indol-2-yl)phenol | Drug Info |
| JNK1 --- JNK3 | trans-4-(4-(1-benzyl-5-(dimethylamino)-1H-pyrazol-4-yl)pyrimidin-2-ylamino)cyclohexanol | Drug Info |
| PR --- mRNA of AR | (Z)-5-(2'-(3'-(E-methylbutenyl)thienylmethylidene))-1,2-dihydro-9-hydroxy-10-methoxy-2,2,4-trimethyl-5H-chromeno[3,4-f]-quinoline | Drug Info |
| Erbeta --- ER | 5-(4-dimethylamino-phenyl)-5,11-dihydro-chromeno[4,3-c]chromene-2,8-diol | Drug Info |
| MEP --- Cathepsin B | 4'-[1-(2-Methoxy-ethyl)-piperidin-4-yloxy]-biphenyl-4-carboxylic acid [1-(cyanomethyl-carbamoyl)-cyclohexyl]-amide | Drug Info |
| PR --- mRNA of AR | 5-(3,5-Dichloro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene | Drug Info |
| Erbeta --- ER | 4-[2-(4-{[2-(4-Chloro-phenoxy)-ethyl]-methyl-amino}-6-piperazin-1-yl-[1,3,5]triazin-2-ylamino)-ethyl]-phenol | Drug Info |
| MEP --- Cathepsin B | 9-(3-hydroxypropyl)-6-(3-(thiophen-3-yl)benzylamino)-9H-purine-2-carbonitrile | Drug Info |
| PR --- mRNA of AR | (Z)-5-(2'-(3'-methoxymethylthienylmethylidene))1,2-dihydro-9-hydroxy-10-methoxy-2,2,4-trimethyl-5H-chromeno[3,4-f]quinoline | Drug Info |
| Erbeta --- ER | 4-{6-Hydroxy-3-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-benzo[b]thiophen-2-yl}-benzonitrile | Drug Info |
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