Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| EGFR3 --- HER2 | CHEMBL258282 | Drug Info |
| TRIP5 --- mRNA of KIF11 | (S)-2-((S)-3-amino-4,4-difluorobutyl)-4-(2,5-difluorophenyl)-N,N-dimethyl-2-phenyl-2H-pyrrole-1(5H)-carboxamide | Drug Info |
| PKCA --- NPKCtheta | 3-(5-(4-(2-hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione | Drug Info |
| HDAC1 --- HD6 | N-hydroxy-3-(3-(1-phenyl-1H-benzo[d]imidazol-2-yl)phenyl)acrylamide | Drug Info |
| EGFR3 --- HER2 | SID85267487 | Drug Info |
| TRIP5 --- mRNA of KIF11 | 5-furanoyl-4-(3-hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-pyrimidine | Drug Info |
| PPAR gamma --- LXRalpha | 2-(5-((3-(8-(trifluoromethyl)quinolin-4-yl)phenyl)methylamino)naphthalen-1-yl)acetic acid | Drug Info |
| HDAC1 --- HD6 | Ethyl 2-oxo-2-(4-{[(1-phenyl-methanoyl)-amino]-methyl}-phenyl)-ethyl trithiocarbonate | Drug Info |
| EGFR3 --- HER2 | N4-(3-bromophenyl)-N6-methylquinazoline-4,6-diamine | Drug Info |
| TRIP5 --- mRNA of KIF11 | N-(3-Chloro-4-fluorobenzyl)-4-furan-2-methyl-1,4-dihydrobenzo[4,5]imidazo[1,2-a]pyrimidine-3-carboxamide | Drug Info |
| PPAR gamma --- PPAR delta | 5-methyl-2-(3-(6-methyl-1H-indol-1-ylsulfonyl)benzamido)benzoic acid | Drug Info |
| HDAC1 --- HD6 | N-hydroxy-3-(3-(1-methyl-1H-benzo[d]imidazol-2-yl)phenyl)acrylamide | Drug Info |
| EGFR3 --- MCSF | (6,7-Dimethyl-quinazolin-4-yl)-methyl-m-tolyl-amine; hydrochloride | Drug Info |
| TRIP5 --- mRNA of KIF11 | SID4253157 | Drug Info |
| PPAR gamma --- PPAR delta | (R)-3-{(S)-4-[(E)-5-(4-{5-[4-(2-Carboxy-2-ethoxy-ethyl)-phenoxy]-3-methyl-pent-3-en-1-ynyl}-phenyl)-3-methyl-pent-2-en-4-ynyloxy]-phenyl}-2-ethoxy-propionic acid | Drug Info |
| HDAC1 --- HDAC2 | N-hydroxy-7-(5-(4-methoxyphenyl)oxazol-2-yl)heptanamide | Drug Info |
| Erbeta --- ER | 4-[1-(1-Methyl-butyl)-1,7a-dihydro-pyrrolo[2,1,5-cd]indolizin-2-yl]-phenol | Drug Info |
| TRIP5 --- mRNA of KIF11 | (S)-4-(2,5-difluorophenyl)-N-(2-hydroxyethyl)-2-(3-hydroxyphenyl)-N-methyl-2H-pyrrole-1(5H)-carboxamide | Drug Info |
| PPAR gamma --- PPAR delta | 3-(1-((2-(3,5-dimethoxyphenyl)-5-methyloxazol-4-yl)methyl)-1H-indol-5-yl)-2-ethoxypropanoic acid | Drug Info |
| HDAC1 --- HDAC2 | 6-Methoxy-1H-indole-2-carboxylic acid (6-hydroxycarbamoyl-hexyl)-amide | Drug Info |
| Erbeta --- ER | 4-[4-(2-hexahydro-1-pyridinylethoxy)phenyl]-3-phenyl-(3S,4R)-3,4-dihydro-2H-7-chromenol | Drug Info |
| TRIP5 --- mRNA of KIF11 | 9-(trifluoromethyl)-3,4,5,11-tetrahydroazepino[2,3-b]carbazol-2(1H)-one | Drug Info |
| PPAR gamma --- PPAR delta | (S)-3-{4-[3,3-Bis-(4-furan-2-yl-phenyl)-allyloxy]-phenyl}-2-ethoxy-propionic acid | Drug Info |
| HDAC1 --- HDAC2 | 4-(3-(3,4-Dimethoxyphenyl)propanamido)-N-hydroxybenzamide | Drug Info |
| Erbeta --- ER | (2S,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-chroman-4-one | Drug Info |
| TRIP5 --- mRNA of KIF11 | SID14743632 | Drug Info |
| PPAR gamma --- PPAR delta | 4-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-propoxy]-phenyl}-butyric acid | Drug Info |
| HDAC1 --- HDAC2 | Thailandepsin B | Drug Info |
| Erbeta --- ER | 4-hydroxy-N-(4-hydroxyphenyl)-N-(3,3,3-trifluoropropyl)benzenesulfonamide | Drug Info |
| TRIP5 --- mRNA of KIF11 | N-(4'-t-butyl-4-biphenylyl)urea | Drug Info |
| PPAR gamma --- PPAR delta | 3-{2-Methyl-4-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-phenyl}-propionic acid | Drug Info |
| HDAC1 --- HDAC4 | (R)-N2-hydroxy-N5-(1-phenylethyl)thiophene-2,5-dicarboxamide | Drug Info |
| Erbeta --- ER | (3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol | Drug Info |
| TRIP5 --- mRNA of KIF11 | 2-Phenyl-3-methyl-6-(4-methylpiperazin-1-yl)-1,4-dihydroquinoline-4-one | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-((2-(3-fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methylselanyl)-2-methylphenoxy)-2-methylpropanoic acid | Drug Info |
| HER2 --- CD221 | trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)cyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-chlorophenyl)-7-chlorobenzo[d]oxazol-2-amine | Drug Info |
| Erbeta --- ER | [5-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanone | Drug Info |
| TRIP5 --- mRNA of KIF11 | N-[3-(methylamino)-4'-(trifluoromethyl)-4-biphenylyl]sulfamide | Drug Info |
| PPAR gamma --- PPAR delta | {4-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-phenyl}-acetic acid | Drug Info |
| HER2 --- MMP-2 | (2S,3S)-N-hydroxy-5-(N-methylisobutyramido)-2-(4-phenyl-1,2,3,6-tetrahydropyridine-1-carbonyl)piperidine-3-carboxamide | Drug Info |
| Erbeta --- ER | 1-(4-bromophenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one | Drug Info |
| Lck --- VEGFR | 4-methyl-N-(2-(3-methyl-2-oxoimidazolidin-1-yl)-5-(trifluoromethyl)phenyl)-3-(2-(methylamino)quinazolin-6-yl)benzamide | Drug Info |
| PPAR gamma --- PPAR delta | 2-{5-[5-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)pentyloxy]-1H-indol-1-yl}ethanoic acid | Drug Info |
| JNK1 --- JNK3 | 3-Morpholino-5-(2-(4-(3-(pyridin-2-yl)-1H-1,2,4-triazol-1-yl)-phenylamino)pyrimidin-4-yl)benzonitrile | Drug Info |
| Erbeta --- ER | 1-(4-{4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino}-6-[2-(4-hydroxy-phenyl)-ethylamino]-[1,3,5]triazin-2-yl}-piperazin-1-yl)-pentan-3-one | Drug Info |
| Src --- VEGFR | (2-Chloro-5-ethoxy-phenyl)-[6-methoxy-7-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-amine | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-(2-(4-hydroxybut-2-ynyloxy)-4-((4-(trifluoromethyl)phenoxy)methyl)phenylthio)-5,6,7,8-tetrahydronaphthalen-1-yloxy)acetic acid | Drug Info |
| JNK1 --- JNK3 | methyl 4-ethyl-2-(2-(4-methoxyphenyl)acetamido)thiophene-3-carboxylate | Drug Info |
| Erbeta --- ER | 9a-butyl-7-hydroxy-3-oxo-2,3,9,9a-tetrahydro-1H-fluorene-4-carbonitrile | Drug Info |
| VEGFR1 --- FGFR1 | methyl 3-(5-(4-(piperidin-1-yl)piperidin-1-yl)-1H-benzo[d]imidazol-2-yl)-1H-indazole-5-carboxylate | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.