Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CAII --- CAI | Hydrochlorothiazide | Drug Info |
| DHFR --- TYMS | 2-{4-[(4-Hydroxy-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid | Drug Info |
| CAII --- CAI | N-(2-Diethylamino-ethyl)-3-(5-sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-benzamide | Drug Info |
| EGFR --- HER2 | (E)-3-(3,4-Dihydroxy-phenyl)-2-(2,4,6-trimethyl-benzoyl)-acrylonitrile | Drug Info |
| CAII --- CAI | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-Heptadecafluoro-nonanoic acid 2-sulfamoyl-benzothiazol-6-yl ester | Drug Info |
| EGFR3 --- Beta PDGFR | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexanol | Drug Info |
| CAII --- CAI | (Carboxymethyl-{[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-methyl}-amino)-acetic acid | Drug Info |
| EGFR3 --- CSrc | (3-Chloro-phenyl)-[3-(3-nitro-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-amine | Drug Info |
| CAII --- CAI | 4-Methyl-5-(nonafluorobutane-1-sulfonylimino)-4,5-dihydro-[1,3,4]thiadiazole-2-sulfonic acid amide | Drug Info |
| EGFR3 --- HER2 | (E)-4-[3-Chloro-4-(3-fluorobenzyloxy)anilino]-6-[3-(3,4-dimethoxycinnamamido)phenoxy]pyrimidine | Drug Info |
| CAII --- CAI | N-(2-bromo-4-sulfamoylphenyl)-2-phenylacetamide | Drug Info |
| EGFR3 --- HER2 | N-[4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl]-2-propynamide | Drug Info |
| CAII --- CAI | 4-{3-[2-(1H-Imidazol-4-yl)-ethyl]-thioureido}-benzenesulfonamide | Drug Info |
| EGFR3 --- HER2 | (4-Benzyloxy-phenyl)-{6-[2-(2-methanesulfonyl-ethylamino)-thiazol-4-yl]-quinazolin-4-yl}-amine | Drug Info |
| CAII --- CAI | Ethyl-((4S,6S)-6-methyl-7,7-dioxo-2-sulfamoyl-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-4-yl)-carbamic acid 2,3-bis-nitrooxy-propyl ester | Drug Info |
| EGFR3 --- HER2 | 4-Azetidin-1-yl-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| CAII --- CAI | 2,6-Dimethyl-4-phenyl-1-[2-(4-sulfamoyl-phenyl)-ethoxycarbonylmethyl]-pyridinium; perchlorate | Drug Info |
| EGFR3 --- HER2 | 2-(2-(4-Nitrobenzylidene)hydrazinyl)thiazol-4(5H)-one | Drug Info |
| CAII --- CAI | 2-Amino-N-[2-(4-sulfamoyl-phenyl)-ethyl]-acetamide | Drug Info |
| EGFR3 --- HER2 | 7-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ylthio)-N-hydroxyheptanamide | Drug Info |
| CAII --- CAI | 4-(2-(((1S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methylsulfonamido)ethyl)benzene sulfonamide | Drug Info |
| EGFR3 --- HER2 | N-(4-(3-chloro-4-fluorophenylamino)-3-cyano-7-methoxyquinolin-6-yl)-4-(diethylamino)pent-2-enamide | Drug Info |
| CAII --- CAI | 1-(3,4-Dichloro-phenyl)-3-(5-mercapto-[1,3,4]thiadiazol-2-yl)-urea | Drug Info |
| CAII --- CAI | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-Heptadecafluoro-nonanoic acid (2-sulfamoyl-phenyl)-amide | Drug Info |
| CAII --- CAI | [(2-{2-[2-(Bis-carboxymethyl-amino)-ethoxy]-ethoxy}-ethyl)-(2-sulfamoyl-benzothiazol-6-yloxycarbonylmethyl)-amino]-acetic acid | Drug Info |
| CAII --- CAI | ((2-Hydroxy-phenyl)-{2-[(2-hydroxy-phenyl)-(4-sulfamoyl-benzyloxycarbonylmethyl)-amino]-ethyl}-amino)-acetic acid | Drug Info |
| CAII --- CAI | N,N-dialkylthio-carbonylsulfenylamino derivative | Drug Info |
| CAII --- CAI | 2-Amino-N-[4-(3-sulfamoyl-phenylsulfamoyl)-phenyl]-acetamide | Drug Info |
| CAII --- CAI | 2-Methylamino-N-(5-sulfamoyl-[1,3,4]thiadiazol-2-yl)-acetamide | Drug Info |
| CAII --- CAI | 3-(2-Amino-acetylamino)-N-(5-sulfamoyl-[1,3,4]thiadiazol-2-yl)-propionamide | Drug Info |
| CAII --- CAIX | Sulfamic acid octadecyl ester | Drug Info |
| CAIX --- CAXII | (E)-7-(2-Butenyloxy)coumarin | Drug Info |
| CALM2 --- Cathepsin B | 3-acetyl-2-(4-tert-butylphenylamino)-8-chloro-6-nitroquinolin-4(1H)-one | Drug Info |
| CALM2 --- Cathepsin B | (R)-1-(2-nitrophenylsulfonyl)-N-((R,S)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide | Drug Info |
| CALM2 --- Cathepsin B | {1-[1-(5-Hydroxy-pentylaminooxalyl)-propylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- Cathepsin B | [3-Methyl-1-(3-{4-methyl-2-[(quinoline-7-carbonyl)-amino]-pentanoylamino}-4-oxo-pyrrolidin-1-ylmethyl)-butyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | 7-(2-cyclohexylethyl)-6-((pyridin-2-yloxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | [(S)-5-[(Morpholine-4-carbonyl)-amino]-1-((R)-1-phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-(4-fluoro-benzyl)-cyclobutylmethyl ester | Drug Info |
| Cathepsin K --- MEP | 4-Methyl-2-(4'-morpholin-2-yl-biphenyl-3-yl)-pentanoic acid cyanomethyl-amide | Drug Info |
| Cathepsin K --- MEP | 4-Methyl-2-(3-pyridin-4-yl-phenyl)-pentanoic acid cyanomethyl-(2,2,2-trifluoro-acetoxy)-amide | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-cyclohexylamino-pyrimidine-5-carboxylic acid [2-(3-methoxyphenyl)-ethyl]-amide | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-(2,2-dimethyl-propylamino)-pyrimidine-5-carboxylic acid [2-(3-methoxy-phenyl)-ethyl]-amide | Drug Info |
| Cathepsin K --- MEP | N-(tert-butoxycarbonyl)-phenylalanyl-glycine-nitrile | Drug Info |
| Cathepsin K --- MEP | N-[1-(2S-Ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-3-fluoro-4-methanesulfonylamino-benzamide | Drug Info |
| CCKBR --- CCKAR | {1-[5-(2-Fluoro-phenyl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester | Drug Info |
| CCKBR --- CCKAR | (S)-4-Bromo-N-[5-(2-fluoro-phenyl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-benzamide | Drug Info |
| CCKBR --- CCKAR | N-(1-Carbamoyl-2-phenyl-ethyl)-3-{[(3R,13R)-3-(1H-indol-3-ylmethyl)-3-methyl-2,5,7-trioxo-1,4,8triaza-cyclotridecane-13-carbonyl]-amino}-succinamic acid | Drug Info |
| CCKBR --- CCKAR | Phenyl-carbamic acid (R)-3-(4-benzoyl-piperidin-1-yl)-3-oxo-2-(3-m-tolyl-ureido)-propyl ester | Drug Info |
| CCKBR --- CCKAR | (S)-3-{(S)-2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[(E)-3-(4-hydroxy-phenyl)-acryloylamino]-hexanoylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-N-methyl-succinamic acid | Drug Info |
| CCKBR --- CCKAR | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(3-sulfooxy-phenyl)-propionylamino]-hexanoylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid; NH40H.hydrate | Drug Info |
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