Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CAII --- CAI | 4-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-ylidenesulfamoyl]-benzoic acid 2-hydroxy-ethyl ester | Drug Info |
| CSrc --- CABL | 9-(2,6-dimethylstyryl)-N-(4-(dimethylphosphoryl)phenyl)-2-methoxy-9H-purin-6-amine | Drug Info |
| CAII --- CAI | {(2-{Carboxymethyl-[2-(4-sulfamoyl-phenyl)-ethoxycarbonylmethyl]-amino}-ethyl)-[2-(4-sulfamoyl-phenyl)-ethoxycarbonylmethyl]-amino}-acetic acid | Drug Info |
| CSrc --- CABL | N-(5-(benzylthio)-1,3,4-thiadiazol-2-yl)-4-fluorobenzamide | Drug Info |
| CAII --- CAI | 2-phenyl-N-(4-sulfamoylphenethyl)acetamide | Drug Info |
| CSrc --- CABL | 4-(2,4-Dichloro-5-methoxy-phenylamino)-6-methoxy-7-(1-methyl-piperidin-4-yloxy)-quinoline-3-carbonitrile | Drug Info |
| CAII --- CAI | {4-Methyl-2-[3-(4-sulfamoyl-phenyl)-thioureido]-pentanoylamino}-acetic acid | Drug Info |
| CSrc --- CD135 | 4-(5-(6-oxo-1,6-dihydropyridin-3-yl)oxazol-2-ylamino)benzenesulfonamide | Drug Info |
| CAII --- CAI | 4-[4-(1,1,2,2,3,3,4,4,4-nonafluorobutylsulfonamido)phenylsulfonamido]-1-benzenesulfonamide | Drug Info |
| CSrc --- FGFR1 | 4-[3-(2,6-Dichloro-phenyl)-1-methyl-2-oxo-1,2-dihydro-[1,6]naphthyridin-7-ylamino]-N,N-diethyl-benzamide | Drug Info |
| CAII --- CAI | sodium 4-chlorobenzoate | Drug Info |
| DHFR --- TYMS | 2-Amino-5-[(4-bromophenyl)sulfanyl]-6-ethylthieno[2,3-d]pyrimidin-4(3H)-one | Drug Info |
| CAII --- CAI | {3-(1H-Imidazol-4-yl)-2-[3-(4-sulfamoyl-phenyl)-thioureido]-propionylamino}-acetic acid | Drug Info |
| EGFR --- HER2 | 3-(3,4-dihydroxyphenyl)-2-(thiophene-2-carbonyl)acrylonitrile | Drug Info |
| CAII --- CAI | sodium 4-(chloromethyl)benzoate | Drug Info |
| EGFR --- Src | 3-{2-[3-(2-Methoxycarbonyl-ethyl)-1H-indol-2-yldisulfanyl]-1H-indol-3-yl}-propionic acid methyl ester | Drug Info |
| CAII --- CAI | 4-((6R,7S,8S,10R,11S,12S,14S,15R)-3,12-Di(R)-hydroxy-7-hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid [2-(5-sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-ethyl]-amide | Drug Info |
| EGFR3 --- CSrc | 4-{2-[3-(4-carboxybenzylcarbamoyl)-1-methyl-1H-2-indolyldisulfanyl]-1-methyl-1H-3-indolylcarboxamidomethyl}benzoic acid1.5 H2O | Drug Info |
| CAII --- CAI | 2-Amino-N-[(5-chloro-2,4-disulfamoyl-phenylcarbamoyl)-methyl]-acetamide | Drug Info |
| EGFR3 --- HER2 | 1-(5-Bromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylthiourea | Drug Info |
| CAII --- CAI | 5-(2-thienylacetamido)-1,3,4-thiadiazole-2-sulfonamide | Drug Info |
| EGFR3 --- HER2 | 2-[5-(2,2-Dicyano-vinyl)-2-hydroxy-3-methoxy-benzylsulfanyl]-benzoic acid anion | Drug Info |
| CAII --- CAI | 2,4,6-Trimethyl-1-(4-sulfamoyl-benzyloxycarbonylmethyl)-pyridinium; perchlorate | Drug Info |
| EGFR3 --- HER2 | N-[4-(4-Benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-2-morpholin-4-ylmethyl-acrylamide | Drug Info |
| CAII --- CAI | 2,6-Diisopropyl-4-phenyl-1-(2-sulfamoyl-benzothiazol-6-yloxycarbonylmethyl)-pyridinium; perchlorate | Drug Info |
| EGFR3 --- HER2 | 4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)-6-aminopyrimidine-5-carbaldehyde O-benzyl oxime | Drug Info |
| CAII --- CAI | 4,5-Dichloro-6-[(7-chloro-2-oxo-2H-chromen-4-ylmethyl)-amino]-benzene-1,3-disulfonic acid diamide | Drug Info |
| EGFR3 --- HER2 | {4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl}-carbamic acid cis-4-amino-4-methylcyclohexyl ester | Drug Info |
| CAII --- CAI | Sulfamic acid propyl ester | Drug Info |
| EGFR3 --- HER2 | 2-(4-Hydroxy-3-methoxy-5-phenylsulfanylmethyl-benzylidene)-malononitrile | Drug Info |
| CAII --- CAI | [(S)-4-Methyl-2-(4-sulfamoyl-benzoylamino)-pentanoylamino]-acetic acid | Drug Info |
| EGFR3 --- HER2 | 4-(3-bromo-2-methylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile | Drug Info |
| CAII --- CAI | 4-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-ylidenesulfamoyl]-benzoic acid 2-dimethylamino-1-methyl-ethyl ester | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| CAII --- CAI | 4-(2-(3-nitrobenzylideneamino)ethyl)benzenesulfonamide | Drug Info |
| CAII --- CAI | {(2-{2-[2-(Bis-carboxymethyl-amino)-ethoxy]-ethoxy}-ethyl)-[(2-bromo-4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-acetic acid; compound with Zn complex | Drug Info |
| CAII --- CAI | 4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesulfonic acid | Drug Info |
| CAII --- CAI | N-(2-chloro-4-sulfamoylphenyl)-2-phenylacetamide | Drug Info |
| CAII --- CAI | 2-[(1E)-{[2-(4-sulfamoylphenyl)ethyl]imino}methyl]phenyl N-[(4-chlorobenzene)sulfonyl]carbamate | Drug Info |
| CAII --- CAI | (S)-3-Methyl-2-[3-(4-sulfamoyl-phenyl)-thioureido]-butyric acid | Drug Info |
| CAII --- CAI | 4-Chloro-N-(5-mercapto-[1,3,4]thiadiazol-2-yl)-3-sulfamoyl-benzamide | Drug Info |
| CAII --- CAIX | 4-Amino-3-bromo-5-iodo-benzenesulfonamide | Drug Info |
| CAII --- CAXII | Resorcinol | Drug Info |
| CAIX --- CAXII | SID29218043 | Drug Info |
| CALM2 --- Cathepsin B | (S)-3-(4-chlorophenylsulfonyl)-N-((R,S)-1-oxo-3-phenylpropan-2-yl)thiazolidine-4-carboxamide | Drug Info |
| CALM2 --- Cathepsin B | {3-Methyl-1-[1-(3-morpholin-4-yl-propylaminooxalyl)-butylcarbamoyl]-butyl}-carbamic acid benzyl ester | Drug Info |
| CALM2 --- Cathepsin B | 5-Amino-N-cyclopropyl-3-(4-isopropylphenyl)-4-oxo-3,4-dihydrothieno[3,4-d]pyridazine-1-carboxamide | Drug Info |
| Cathepsin K --- Cathepsin B | [(S)-2-Pyridin-3-yl-1-((5S,6R)-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-ethyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | 2-(cyclohexylmethyl)-N-(4-(methylsulfonyl)-1-(4-(trifluoromethoxy)phenylamino)butan-2-yl)-4-morpholino-4-oxobutanamide | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-cyclohexylamino-pyrimidine-5-carboxylic acid [2-(4-pyrrolin-1-ylphenyl)-ethyl]-amide | Drug Info |
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