Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CAII --- CAI | 3-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-benzoic acid 2-dimethylamino-1-methyl-ethyl ester | Drug Info |
| CSrc --- CABL | N-(3-bromophenyl)-1-(2-chloro-2-(4-fluorophenyl)ethyl)-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| CAII --- CAI | 4-(4-(4-fluoro-3-methylphenyl)-1H-1,2,3-triazol-1-yl)benzenesulfonamide | Drug Info |
| CSrc --- CABL | (E)-3-(2-(6-(cyclopropylamino)-9H-purin-9-yl)vinyl)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)-phenyl)benzamide | Drug Info |
| CAII --- CAI | [Carboxymethyl-(2-{carboxymethyl-[2-(carboxymethyl-{[2-(5-sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-ethylcarbamoyl]-methyl}-amino)-ethyl]-amino}-ethyl)-amino]-acetic acid | Drug Info |
| CSrc --- CABL | N-Benzyl-1-(2-chloro-2-phenylethyl)-6-(methylsulfonyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| CAII --- CAI | (sulfamoylamino)benzene | Drug Info |
| CSrc --- CABL | 9-(2,6-dimethylstyryl)-N-(4-(dimethylphosphoryl)phenyl)-2-(2-methoxyethoxy)-9H-purin-6-amine | Drug Info |
| CAII --- CAI | 2-Amino-N-[(2-iodo-4-sulfamoyl-phenylcarbamoyl)-methyl]-acetamide | Drug Info |
| CSrc --- CDK4 | Granulatimide | Drug Info |
| CAII --- CAI | N-(2-chloro-4-sulfamoylphenyl)-2-(thiophen-2-yl)acetamide | Drug Info |
| DHFR --- TYMS | 2-Amino-5-[(4-fluorophenyl)sulfanyl]-6-methylthieno[2,3-d]pyrimidin-4(3H)-one | Drug Info |
| CAII --- CAI | 1-naphthalene boronic acid | Drug Info |
| DHFR --- TYMS | N-[4-[(2,4-Diamino-5-propyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)sulfanyl]benzoyl]-L-glutamic Acid | Drug Info |
| CAII --- CAI | 1-[(2,4-Disulfamoyl-5-trifluoromethyl-phenylcarbamoyl)-methyl]-2,4,6-trimethyl-pyridinium; perchlorate | Drug Info |
| EGFR --- HER2 | (E)-2-Cyano-3-(3,4-dihydroxy-phenyl)-N-(2,6-dimethyl-phenyl)-acrylamide | Drug Info |
| CAII --- CAI | 2-Propyl-pentanoic acid 2-(4-sulfamoyl-phenyl)-ethyl ester | Drug Info |
| EGFR3 --- Beta PDGFR | SID855715 | Drug Info |
| CAII --- CAI | 3-[({4-[(aminocarbonyl)amino]phenyl}sulfonyl)amino]benzenesulfonamide | Drug Info |
| EGFR3 --- CSrc | {2-[3-(Furan-2-carbonyl)-1-methyl-1H-indol-2-yldisulfanyl]-1-methyl-1H-indol-3-yl}-furan-2-yl-methanone | Drug Info |
| CAII --- CAI | 2,6-Dimethyl-4-phenyl-1-[(2-sulfamoyl-benzothiazol-6-ylcarbamoyl)-methyl]-pyridinium; perchlorate | Drug Info |
| EGFR3 --- HER2 | 3-(3-Benzylsulfanylmethyl-4-hydroxy-5-methoxy-phenyl)-2-(3,4-dihydroxy-benzoyl)-acrylonitrile | Drug Info |
| CAII --- CAI | (R)-4-((8S,10S,12S,14R,15R,17S)-10,13-Dimethyl-3,7,12-trioxo-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid (2-iodo-4-sulfamoyl-phenyl)-amide | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(3-chloro-4-(pyridin-2-yloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| CAII --- CAI | 6-(2-Hydroxy-ethoxy)-benzothiazole-2-sulfonic acid (2-amino-acetyl)-amide | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(2-methoxy-benzyloxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide | Drug Info |
| CAII --- CAI | SID528890 | Drug Info |
| EGFR3 --- HER2 | (R)-7-(4-(1-(4-Chlorophenyl)ethylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide | Drug Info |
| CAII --- CAI | (R)-4-((8S,10S,12S,14R,15R,17S)-10,13-Dimethyl-3,7,12-trioxo-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid (2-fluoro-4-sulfamoyl-phenyl)-amide | Drug Info |
| EGFR3 --- HER2 | 4-(3-chloro-4-hydroxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile | Drug Info |
| CAII --- CAI | 6-Nitrooxy-hexanoic acid ethyl-((4S,6S)-6-methyl-7,7-dioxo-2-sulfamoyl-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-4-yl)-amide | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(3-cyano-benzyloxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide | Drug Info |
| CAII --- CAI | N-2-naphthylsulfamide | Drug Info |
| EGFR3 --- HER2 | 4-[3-Chloro-4-(3-fluorobenzyloxy)anilino]-6-[3-(2,4,5-trifluorophenylacetamido)phenoxy]pyrimidine | Drug Info |
| CAII --- CAI | N-(2-Diethylamino-ethyl)-4-[3-methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-ylidenesulfamoyl]-benzamide | Drug Info |
| CAII --- CAI | {[2-(Bis-carboxymethyl-amino)-ethyl]-[(3-methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-2-ylidenecarbamoyl)-methyl]-amino}-acetic acid | Drug Info |
| CAII --- CAI | Furan-2-carboxylic acid [3-methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-ylidene]-amide | Drug Info |
| CAII --- CAI | N-cyclohexylsulfamide | Drug Info |
| CAII --- CAI | 4-Methyl-5-trifluoromethanesulfonylimino-4,5-dihydro-[1,3,4]thiadiazole-2-sulfonic acid amide | Drug Info |
| CAII --- CAI | {{2-[2-(2-{Carboxymethyl-[(5-sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-methyl]-amino}-ethoxy)-ethoxy]-ethyl}-[(5-sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-methyl]-amino}-acetic acid; compound with Zn complex | Drug Info |
| CAII --- CAI | {(2-{2-[2-(Bis-carboxymethyl-amino)-ethoxy]-ethoxy}-ethyl)-[(2-fluoro-4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-acetic acid | Drug Info |
| CAII --- CAI | [{2-[[(2-Fluoro-4-sulfamoyl-phenylcarbamoyl)-methyl]-(2-hydroxy-phenyl)-amino]-ethyl}-(2-hydroxy-phenyl)-amino]-acetic acid | Drug Info |
| CAII --- CAIX | 2-Isopropyl-4,6-diphenyl-1-[2-(4-sulfamoyl-phenyl)-ethyl]-pyridinium; perchlorate | Drug Info |
| CAIX --- CAXII | ethyl 7-methoxy-2-oxo-2H-chromene-3-carboxylate | Drug Info |
| CALM2 --- Cathepsin B | (1-{1-Benzyl-2-oxo-2-[(quinolin-2-ylmethyl)-carbamoyl]-ethylcarbamoyl}-3-methyl-butyl)-carbamic acid benzyl ester | Drug Info |
| CALM2 --- Cathepsin B | N-(1-Carbamoyl-2-phenyl-ethyl)-2-[2-(4-diethylaminomethyl-phenyl)-vinyl]-benzamide | Drug Info |
| CALM2 --- Cathepsin B | (S)-4-Methyl-2-[2-(naphthalene-2-sulfonyl)-ethyl]-pentanoic acid ((S)-1-formyl-3-methyl-butyl)-amide | Drug Info |
| Cathepsin K --- Cathepsin B | [(S)-1-((5S,6S)-7-Oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-2-phenyl-propyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid (S)-(1,2,3,4-tetrahydro-naphthalen-1-yl) ester | Drug Info |
| Cathepsin K --- MEP | 6-[4-(4-Acetyl-piperazin-1-yl)-phenoxymethyl]-7-(2-cyclopentyl-ethyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.