Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CAII --- CAI | piperidine-1-sulfonamide | Drug Info |
| CSrc --- CABL | 4-amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine | Drug Info |
| CAII --- CAI | (S)-3-Phenyl-2-[3-(4-sulfamoyl-phenyl)-thioureido]-propionic acid methylcarbamoylmethyl with resin | Drug Info |
| CSrc --- CABL | 1-[2-Chloro-2-(4-chlorophenyl)ethyl]-N-(pyridin-2-ylmethyl)-1Hpyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| CAII --- CAI | 2(R)-2-(2,3,6-tribromo-4,5-dihydroxybenzyl)cyclohexanone | Drug Info |
| CSrc --- FGFR1 | 3-(4-Chloro-phenyl)-1-oxo-1H-indene-2-carboxylic acid amide | Drug Info |
| CAII --- CAI | (2S,3R)-3-Methyl-2-(4-sulfamoyl-benzoylamino)-pentanoic acid | Drug Info |
| DHFR --- TYMS | 4-{4-[4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)-ethynyl-amino]-benzoylamino}-4-carboxy-butyrylamino)-4-carboxy-butyrylamino]-4-carboxy-butyrylamino}-4-carboxy-butyric acid anion | Drug Info |
| CAII --- CAI | N,N-dialkylthio-carbonylsulfenylamino derivative | Drug Info |
| DHFR --- TYMS | 2-Amino-5-[(2,5-dimethoxyphenyl)sulfanyl]-6-ethylthieno[2,3-d]pyrimidin-4(3H)-one | Drug Info |
| CAII --- CAI | SID144209571 | Drug Info |
| EGFR --- PDGFR | 6-(2,6-dichlorophenyl)-2-(dimethylamino)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one | Drug Info |
| CAII --- CAI | biphenyl-4-ylboronic acid | Drug Info |
| EGFR3 --- CSrc | ({2-[3-(Carboxymethyl-carbamoyl)-1-methyl-1H-indol-2-yldisulfanyl]-1-methyl-1H-indole-3-carbonyl}-amino)-acetic acid | Drug Info |
| CAII --- CAI | Ethyl1-(3-((4-hydroxyphenyl)diazenyl)phenyl)-5-phenyl-3-(5-sulfamoyl-1,3,4-thiadiazol-2-ylcarbamoyl)-1H-pyrazole-4-carboxylate | Drug Info |
| EGFR3 --- HER2 | (S)-N-(2-hydroxyethyl)-N-methyl-2-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-5-yloxy)propanamide | Drug Info |
| CAII --- CAI | 3-Bromo-4-(heptadecafluorooctane-1-sulfonylamino)-benzenesulfonamide | Drug Info |
| EGFR3 --- HER2 | 3-[3-(Benzothiazol-2-ylsulfanylmethyl)-4,5-dihydroxy-phenyl]-2-cyano-acrylamide | Drug Info |
| CAII --- CAI | SID526204 | Drug Info |
| EGFR3 --- HER2 | N-[1-(3-Fluoro-benzyl)-1H-indazol-5-yl]-5-[piperidin-1-yliminomethyl]-pyrimidine-4,6-diamine | Drug Info |
| CAII --- CAI | 2-Amino-N-[3-methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2Z)-ylidene]-acetamide | Drug Info |
| EGFR3 --- HER2 | 4-(3'-bromoanilino)-6,7-dimethoxyquinazoline hydrochloride | Drug Info |
| CAII --- CAI | 2,4,6-Trimethyl-1-{[4-(3-sulfamoyl-phenylsulfamoyl)-phenylcarbamoyl]-methyl}-pyridinium; perchlorate | Drug Info |
| EGFR3 --- HER2 | TCMDC-138467 | Drug Info |
| CAII --- CAI | 2,3,5,6-Tetrafluoro-N-(4-sulfamoyl-phenyl)-benzenesulfonamide | Drug Info |
| EGFR3 --- HER2 | (E)-3-[3-(1H-Benzoimidazol-2-ylsulfanylmethyl)-4-hydroxy-5-methoxy-phenyl]-2-cyano-acrylamide | Drug Info |
| CAII --- CAI | {{2-[2-(2-{Carboxymethyl-[(4-sulfamoyl-benzylcarbamoyl)-methyl]-amino}-ethoxy)-ethoxy]-ethyl}-[(4-sulfamoyl-benzylcarbamoyl)-methyl]-amino}-acetic acid | Drug Info |
| EGFR3 --- HER2 | 2-(2-(4-Chlorobenzylidene)hydrazinyl)thiazol-4(5H)-one | Drug Info |
| CAII --- CAI | [(S)-3-(3H-Imidazol-4-yl)-2-(4-sulfamoyl-benzoylamino)-propionylamino]-acetic acid | Drug Info |
| EGFR3 --- HER2 | 4-[(3-chlorophenyl)amino]-6-(methylamino)quinazoline | Drug Info |
| CAII --- CAI | 5-(Heptadecafluorooctane-1-sulfonylimino)-4-methyl-4,5-dihydro-[1,3,4]thiadiazole-2-sulfonic acid amide | Drug Info |
| CAII --- CAI | {{2-[Carboxymethyl-(2-{carboxymethyl-[(5-chloro-2,4-disulfamoyl-phenylcarbamoyl)-methyl]-amino}-ethyl)-amino]-ethyl}-[(5-chloro-2,4-disulfamoyl-phenylcarbamoyl)-methyl]-amino}-acetic acid | Drug Info |
| CAII --- CAI | N-(2,3-Dichloro-4,6-disulfamoyl-phenyl)-2-(N-methyl-guanidino)-acetamide | Drug Info |
| CAII --- CAI | 3-(1H-Imidazol-4-yl)-2-{3-[3-(4-sulfamoyl-phenyl)-thioureido]-propionylamino}-propionic acid | Drug Info |
| CAII --- CAI | {{2-[2-(2-{Carboxymethyl-[(4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-ethoxy)-ethoxy]-ethyl}-[(4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-acetic acid | Drug Info |
| CAII --- CAI | 6-Pentafluorobenzenesulfonylamino-benzothiazole-2-sulfonic acid amide | Drug Info |
| CAII --- CAI | (S)-2-[3-(4-Sulfamoyl-phenyl)-thioureido]-succinamic acid methylcarbamoylmethyl with resin | Drug Info |
| CAII --- CAI | 6-(2-Sulfamoyl-benzothiazol-6-ylcarbamoyl)-pyridine-2-carboxylic acid | Drug Info |
| CAII --- CAIX | 4-(bis(4-methylpiperidin-1-yl)amino)-N-(4-sulfamoylphenyl)butanamide | Drug Info |
| CAIX --- CAXII | 2'-(2-oxo-2H-chromen-7-yloxy)ethyl4''-methylbenzenesulfonate | Drug Info |
| CALM2 --- Cathepsin B | (R)-1-(naphthalen-1-ylsulfonyl)-N-((R,S)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide | Drug Info |
| CALM2 --- Cathepsin B | (R)-1-(4-methoxyphenylsulfonyl)-N-((R,S)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide | Drug Info |
| CALM2 --- Cathepsin B | [1-(1-Benzylaminooxalyl-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- Cathepsin B | (R)-N-(1-cyano-cyclopropyl)-3-methanesulfonyl-2-[(S)-2,2,2-trifluoro-1-(4'-fluoro-biphenyl-4-yl)-ethylamino]-propionamide | Drug Info |
| Cathepsin K --- MEP | N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]benzoyl}-leucyl-glycine-nitrile | Drug Info |
| Cathepsin K --- MEP | N-((S)-1-((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)-3-(1-methylcyclohexyl)-1-oxopropan-2-yl)furan-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | [1-(3-Methoxy-1-methyl-2-oxo-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | 2-(cyclohexylmethyl)-4-morpholino-4-oxo-N-(1-(4-(trifluoromethoxy)phenylamino)propan-2-yl)butanamide | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-cyclohexylamino-pyrimidine-5-carboxylic acid [2-(3-methoxyphenyl)-ethyl]-amide | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-(2,2-dimethyl-propylamino)-pyrimidine-5-carboxylic acid [2-(3-methoxy-phenyl)-ethyl]-amide | Drug Info |
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